Vectorial transport of nucleoside analogs from the apical to the basolateral membrane in double-transfected cells expressing the human concentrative nucleoside transporter hCNT3 and the export pump ABCC4

Drug Metabolism and Disposition

Volumn 38, Issue 7, 2010, Pages 1054-1063

  Rius, Maria ^a   Keller, Daniela ^a   Brom, Manuela ^a   Hummel Eisenbeiss, Johanna ^a   Lyko, Frank ^a   Keppler, Dietrich ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; ABC TRANSPORTER; ABC TRANSPORTER C4; AZACITIDINE; HUMAN CONCENTRATIVE NUCLEOSIDE TRANSPORTER 3; NITROBENZYLTHIOINOSINE; NUCLEOSIDE ANALOG; NUCLEOSIDE TRANSPORTER; UNCLASSIFIED DRUG; URIDINE; [2 14 C]CYTIDINE; [5 3 H]URIDINE; [6 3H]5 FLUORO 5' DEOXYURIDINE; ABCC4 PROTEIN, HUMAN; CARRIER PROTEIN; CIF NUCLEOSIDE TRANSPORTER; MULTIDRUG RESISTANCE PROTEIN; NUCLEOSIDE;

ANIMAL CELL; ANIMAL MODEL; APICAL MEMBRANE; ARTICLE; BASOLATERAL MEMBRANE; CELL TRANSPORT; CONTROLLED STUDY; DOG; DRUG TRANSPORT; GENETIC TRANSFECTION; HUMAN; HUMAN TISSUE; KIDNEY CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PANCREAS ADENOCARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; ANIMAL; BIOSYNTHESIS; ENZYME SPECIFICITY; GENETICS; METABOLISM; PANCREAS; PANCREAS TUMOR; TRANSFORMED CELL LINE; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; AZACITIDINE; BIOLOGICAL TRANSPORT; CELL LINE, TRANSFORMED; DOGS; HUMANS; MEMBRANE TRANSPORT PROTEINS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; NUCLEOSIDES; PANCREAS; PANCREATIC NEOPLASMS; SUBSTRATE SPECIFICITY; TRANSFECTION;

EID: 77952171136     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.110.032664     Document Type: Article

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