Low-dose erythropoietin inhibits oxidative stress and early vascular changes in the experimental diabetic retina

Diabetologia

Volumn 53, Issue 6, 2010, Pages 1227-1238

  Wang, Q ^a   Pfister, F ^a   Dorn Beineke, A ^a   Vom Hagen, F ^a   Lin, J ^a   Feng, Y ^a   Hammes, H P ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Diabetic retinopathy; Erythropoietin; Oxidative stress; Pericyte loss

Indexed keywords

3 NITROTYROSINE; 6 N CARBOXYMETHYLLYSINE; ADVANCED GLYCATION END PRODUCT; ANGIOPOIETIN 2; HEAT SHOCK PROTEIN 27; PROTEIN KINASE B; RECOMBINANT ERYTHROPOIETIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DIABETIC RETINOPATHY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG MEGADOSE; ENZYME ACTIVATION; LOW DRUG DOSE; MALE; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; PERICYTE; PRIMARY PREVENTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STREPTOZOCIN DIABETES;

ANALYSIS OF VARIANCE; ANGIOPOIETIN-2; ANIMALS; BLOOD GLUCOSE; BLOTTING, WESTERN; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC RETINOPATHY; ERYTHROPOIESIS; ERYTHROPOIETIN; FLUORESCENT ANTIBODY TECHNIQUE; MALE; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; RETINA; RETINAL VESSELS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 77952092884     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-010-1727-7     Document Type: Article

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