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Volumn 29, Issue 2, 2010, Pages 153-160

Generation and characterization of four novel monoclonal antibodies against human programmed death-1 molecule

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G1; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 1F8; MONOCLONAL ANTIBODY 4B9; MONOCLONAL ANTIBODY 8F5; MONOCLONAL ANTIBODY 9H1; PROGRAMMED DEATH 1 RECEPTOR; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; LEUKOCYTE ANTIGEN; PDCD1 PROTEIN, HUMAN;

EID: 77952061452     PISSN: 15540014     EISSN: None     Source Type: Journal    
DOI: 10.1089/hyb.2009.0091     Document Type: Article
Times cited : (7)

References (35)
  • 1
    • 0033534678 scopus 로고    scopus 로고
    • From TCR engagement to T cell activation: A kinetic view of T cell behavior
    • Lanzavecchia A, Lezzi G, and Viola A: From TCR engagement to T cell activation: a kinetic view of T cell behavior. Cell 1999;96:1-4.
    • (1999) Cell. , vol.96 , pp. 1-4
    • Lanzavecchia, A.1    Lezzi, G.2    Viola, A.3
  • 8
    • 0026700235 scopus 로고
    • Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death
    • Ishida Y, Agata Y, Shibahara K, and Honjo T: Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. EMBO J 1992;11:3887-3895.
    • (1992) EMBO J. , vol.11 , pp. 3887-3895
    • Ishida, Y.1    Agata, Y.2    Shibahara, K.3    Honjo, T.4
  • 9
    • 3142688997 scopus 로고    scopus 로고
    • SHP-1 and SHP-2 associate with immunoreceptor tyrosinebased switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation
    • Chemnitz JM, Parry RV, Nichols KE, June CH, and Riley JL: SHP-1 and SHP-2 associate with immunoreceptor tyrosinebased switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation. J Immunol 2004;173:945-954.
    • (2004) J. Immunol. , vol.173 , pp. 945-954
    • Chemnitz, J.M.1    Parry, R.V.2    Nichols, K.E.3    June, C.H.4    Riley, J.L.5
  • 10
    • 0032736029 scopus 로고    scopus 로고
    • B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion
    • Dong H, Zhu G, Tamada K, and Chen L: B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion. Nat Med 1999;5:1365-1369.
    • (1999) Nat. Med. , vol.5 , pp. 1365-1369
    • Dong, H.1    Zhu, G.2    Tamada, K.3    Chen, L.4
  • 13
    • 0142149029 scopus 로고    scopus 로고
    • Absence of programmed death receptor 1 alters thymic development and enhances generation of CD4/CD8 double-negative TCR-transgenic T cells
    • Blank C, Brown I, Marks R, Nishimura H, Honjo T, and Gajewski TF: Absence of programmed death receptor 1 alters thymic development and enhances generation of CD4/CD8 double-negative TCR-transgenic T cells. J Immunol 2003;171:4574-4581.
    • (2003) J. Immunol. , vol.171 , pp. 4574-4581
    • Blank, C.1    Brown, I.2    Marks, R.3    Nishimura, H.4    Honjo, T.5    Gajewski, T.F.6
  • 15
    • 33644847590 scopus 로고    scopus 로고
    • Differential role of programmed death-ligand 1 and programmed death-ligand 2 in regulating the susceptibility and chronic progression of experimental autoimmune encephalomyelitis
    • Zhu B, Guleria I, Khosroshahi A, Chitnis T, Imitola J, Azuma M, Yagita H, Sayegh MH, and Khoury SJ: Differential role of programmed death-ligand 1 and programmed death-ligand 2 in regulating the susceptibility and chronic progression of experimental autoimmune encephalomyelitis. J Immunol 2006;176:3480-3489.
    • (2006) J. Immunol. , vol.176 , pp. 3480-3489
    • Zhu, B.1    Guleria, I.2    Khosroshahi, A.3    Chitnis, T.4    Imitola, J.5    Azuma, M.6    Yagita, H.7    Sayegh, M.H.8    Khoury, S.J.9
  • 16
    • 77952080272 scopus 로고    scopus 로고
    • Costimulatory pathways in multiple sclerosis: Distinctive expression of PD-1 and PD-L1 in patients with different patterns of disease
    • Trabattoni D, Saresella M, Pacei M, Marventano I, Mendozzi L, Rovaris M, Caputo D, Borelli M, and Clerici M: Costimulatory pathways in multiple sclerosis: distinctive expression of PD-1 and PD-L1 in patients with different patterns of disease. J Immunol 2009;183:4984-4993.
    • (2009) J. Immunol. , vol.183 , pp. 4984-4993
    • Trabattoni, D.1    Saresella, M.2    Pacei, M.3    Marventano, I.4    Mendozzi, L.5    Rovaris, M.6    Caputo, D.7    Borelli, M.8    Clerici, M.9
  • 19
    • 0037126021 scopus 로고    scopus 로고
    • Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade
    • Iwai Y, Ishida M, Tanaka Y, Okazaki T, Honjo T, and Minato N: Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade. Proc Natl Acad Sci USA 2002;99:12293-12297.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 12293-12297
    • Iwai, Y.1    Ishida, M.2    Tanaka, Y.3    Okazaki, T.4    Honjo, T.5    Minato, N.6
  • 20
    • 34848900497 scopus 로고    scopus 로고
    • Programmed death-1 blockade enhances expansion and functional capacity of human melanoma antigen-specific CTLs
    • Wong RM, Scotland RR, Lau RL, Wang C, Korman AJ, Kast WM, and Weber JS: Programmed death-1 blockade enhances expansion and functional capacity of human melanoma antigen-specific CTLs. Int Immunol 2007;19:1223-1234.
    • (2007) Int. Immunol. , vol.19 , pp. 1223-1234
    • Wong, R.M.1    Scotland, R.R.2    Lau, R.L.3    Wang, C.4    Korman, A.J.5    Kast, W.M.6    Weber, J.S.7
  • 23
    • 11244268818 scopus 로고    scopus 로고
    • Cord blood CD4 (+) CD25 (+)-derived T regulatory cell lines express FoxP3 protein and manifest potent suppressor function
    • Godfrey WR, Spoden DJ, Ge YG, Baker SR, Liu B, Levine BL, June CH, Blazar BR, and Porter SB: Cord blood CD4 (+) CD25 (+)-derived T regulatory cell lines express FoxP3 protein and manifest potent suppressor function. Blood 2005;105:750-758.
    • (2005) Blood , vol.105 , pp. 750-758
    • Godfrey, W.R.1    Spoden, D.J.2    Ge, Y.G.3    Baker, S.R.4    Liu, B.5    Levine, B.L.6    June, C.H.7    Blazar, B.R.8    Porter, S.B.9
  • 25
    • 49649114804 scopus 로고    scopus 로고
    • Phase I safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies
    • Berger R, Rotem-Yehudar R, Slama G, Landes S, Kneller A, Leiba M, Koren-Michowitz M, Shimoni A, and Nagler A: Phase I safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies. Clin Cancer Res 2008;14:3044-3051.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 3044-3051
    • Berger, R.1    Rotem-Yehudar, R.2    Slama, G.3    Landes, S.4    Kneller, A.5    Leiba, M.6    Koren-Michowitz, M.7    Shimoni, A.8    Nagler, A.9
  • 27
    • 68949124858 scopus 로고    scopus 로고
    • A novel agonist anti-human OX40L monoclonal antibody that stimulates T cell proliferation and enhances cytokine secretion
    • Wang Q, Chen Y, Xie F, Ge Y, Wang X, and Zhang X: A novel agonist anti-human OX40L monoclonal antibody that stimulates T cell proliferation and enhances cytokine secretion. Hybridoma 2009;28:269-276.
    • (2009) Hybridoma , vol.28 , pp. 269-276
    • Wang, Q.1    Chen, Y.2    Xie, F.3    Ge, Y.4    Wang, X.5    Zhang, X.6
  • 28
    • 17644389199 scopus 로고    scopus 로고
    • TNF/TNFR family members in costimulation of T cell responses
    • Watts TH: TNF/TNFR family members in costimulation of T cell responses. Annu Rev Immunol 2005;23:23-68.
    • (2005) Annu. Rev. Immunol. , vol.23 , pp. 23-68
    • Watts, T.H.1
  • 31
    • 70349561448 scopus 로고    scopus 로고
    • PD-1/PD-L1 interactions inhibit antitumor immune responses in a murine acute myeloid leukemia model
    • Zhang L, Gajewski TF, and Kline J: PD-1/PD-L1 interactions inhibit antitumor immune responses in a murine acute myeloid leukemia model. Blood 2009;114:1545-1552.
    • (2009) Blood , vol.114 , pp. 1545-1552
    • Zhang, L.1    Gajewski, T.F.2    Kline, J.3
  • 34
    • 34248185086 scopus 로고    scopus 로고
    • B7-H1 up-regulation on myeloid dendritic cells significantly suppresses T cell immune function in patients with chronic hepatitis B
    • Chen L, Zhang Z, Chen W, Zhang Z, Li Y, Shi M, Zhang J, Chen L, Wang S, and Wang FS: B7-H1 up-regulation on myeloid dendritic cells significantly suppresses T cell immune function in patients with chronic hepatitis B. J Immunol 2007;178:6634-6641.
    • (2007) J. Immunol. , vol.178 , pp. 6634-6641
    • Chen, L.1    Zhang, Z.2    Chen, W.3    Zhang, Z.4    Li, Y.5    Shi, M.6    Zhang, J.7    Chen, L.8    Wang, S.9    Wang, F.S.10
  • 35
    • 70449475132 scopus 로고    scopus 로고
    • Blocking PD-1 in cancer immunotherapy
    • Dotti G: Blocking PD-1 in cancer immunotherapy. Blood 2009;114:1457-1458.
    • (2009) Blood , vol.114 , pp. 1457-1458
    • Dotti, G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.