SCOPUS 정보 검색 플랫폼

Journal of Molecular Catalysis B: Enzymatic

Volumn 64, Issue 3-4, 2010, Pages 120-122

The role of polymorphic cytochrome P450 enzymes in drug design, development and drug interactions with a special emphasis on phenotyping

(1) Arinç, Emel a

a MIDDLE EAST TECHNICAL UNIVERSITY (Turkey)

Author keywords

Cytochrome P450; Drug design; Metabolism; Pharmacogenetis; Phenotyping

Indexed keywords

CYTOCHROME P450; DRUG DESIGN; DRUG METABOLISMS; GENETIC POLYMORPHISMS; PHENOTYPING; POLYMORPHIC CYTOCHROME; THERAPEUTIC FAILURE;

DESIGN; METABOLISM;

DRUG INTERACTIONS;

ANASTROZOLE; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 2A6; CYTOCHROME P450 2B6; CYTOCHROME P450 2C8; CYTOCHROME P450 2D6; CYTOCHROME P450 2E1; CYTOCHROME P450 3A4; DRUG METABOLITE; DRUG METABOLIZING ENZYME; ENDOXIFEN; FADROZOLE; KETOCONAZOLE; LANOSTEROL; LETROZOLE; PAROXETINE; POLYCHLORINATED BIPHENYL DERIVATIVE; POLYCYCLIC AROMATIC HYDROCARBON; TAMOXIFEN; UNCLASSIFIED DRUG;

BREAST CANCER; BREAST TUMOR; CARCINOGENICITY; CHEMICAL CARCINOGENESIS; COMPETITIVE INHIBITION; DRUG ANTAGONISM; DRUG BLOOD LEVEL; DRUG DESIGN; DRUG EFFICACY; DRUG METABOLISM; DRUG TARGETING; ENZYME POLYMORPHISM; ETHNIC DIFFERENCE; GENE DELETION; GENE MUTATION; HUMAN; MYCOSIS; PHARMACOGENETICS; PHENOTYPE; PRODUCT DEVELOPMENT; PROSTATE CANCER; REVIEW;

EID: 77951977439 PISSN: 13811177 EISSN: None Source Type: Journal
DOI: 10.1016/j.molcatb.2009.03.020 Document Type: Review

Times cited : (13)

References (23)

1
- 0027399930
- Ari{dotless}nç E., and Sen A. Comp. Biochem. Physiol. 104B (1993) 133-139
- (1993) Comp. Biochem. Physiol. , vol.104 B , pp. 133-139
- Arinç, E.¹ Sen, A.²

2
- 77951978480
- Lu A.Y.H., Ari{dotless}nç E., Schenkman J.B., and Hodgson E. (Eds), Springer-Verlag, Heidelberg
- In: Lu A.Y.H., Ari{dotless}nç E., Schenkman J.B., and Hodgson E. (Eds). Molecular Aspects of Oxidative Drug Metabolizing Enzymes: Their Significance in Environmental Toxicology, Chemical Carcinogenesis and Health (1995), Springer-Verlag, Heidelberg 503-513
- (1995) Molecular Aspects of Oxidative Drug Metabolizing Enzymes: Their Significance in Environmental Toxicology, Chemical Carcinogenesis and Health , pp. 503-513

3
- 24344479624
- Manders J.B., and Gradishar W.J. Breast Cancer 12 (2005) 62-72
- (2005) Breast Cancer , vol.12 , pp. 62-72
- Manders, J.B.¹ Gradishar, W.J.²

4
- 77951978543
- Vanden Bossche H., Marichal P., Willenses G., Janssen P.A.J., Ari{dotless}nç E., Schenkman J.B., and Hodgson E. (Eds), Plenum Press, New York
- In: Vanden Bossche H., Marichal P., Willenses G., Janssen P.A.J., Ari{dotless}nç E., Schenkman J.B., and Hodgson E. (Eds). Molecular and Applied Aspects of Oxidative Drug Metabolizing Enzymes (1989), Plenum Press, New York 345-363
- (1989) Molecular and Applied Aspects of Oxidative Drug Metabolizing Enzymes , pp. 345-363

5
- 33644664657
- Ingelman-Sundberg M., and Rodriguez-Antona C. Phil. Trans. R. Soc. 360 (2005) 1563-1570
- (2005) Phil. Trans. R. Soc. , vol.360 , pp. 1563-1570
- Ingelman-Sundberg, M.¹ Rodriguez-Antona, C.²

6
- 0017116574
- Ari{dotless}nç E., and Philpot R.M. J. Biol. Chem. 251 (1976) 3213-3220
- (1976) J. Biol. Chem. , vol.251 , pp. 3213-3220
- Arinç, E.¹ Philpot, R.M.²

7
- 0025012272
- Adali O., and Ari{dotless}nç E. Int. J. Biochem. 22 (1990) 1433-1444
- (1990) Int. J. Biochem. , vol.22 , pp. 1433-1444
- Adali, O.¹ Arinç, E.²

8
- 0001594033
- Ari{dotless}nç E., Schenkman J.B., and Greim H. (Eds), Springer-Verlag, Heidelberg
- In: Ari{dotless}nç E., Schenkman J.B., and Greim H. (Eds). Handbook of Experimental Pharmacology Cytochrome P450 vol. 105 (1993), Springer-Verlag, Heidelberg 373-386
- (1993) Handbook of Experimental Pharmacology Cytochrome P450 , vol.105 , pp. 373-386

9
- 0032793249
- Ingelman-Sundberg M., Oscarson M., and McLellan R.A. Trends Pharmacol. Sci. 20 (1999) 342-349
- (1999) Trends Pharmacol. Sci. , vol.20 , pp. 342-349
- Ingelman-Sundberg, M.¹ Oscarson, M.² McLellan, R.A.³

10
- 0034583282
- Ari{dotless}nç E., Şen A., and Bozcaarmutlu B. Pure Appl. Chem. 72 (2000) 985-994
- (2000) Pure Appl. Chem. , vol.72 , pp. 985-994
- Arinç, E.¹ Şen, A.² Bozcaarmutlu, B.³

11
- 23944434253
- Ari{dotless}nç E., Arslan S., and Adali O. Arch. Toxicol. 79 (2005) 427-433
- (2005) Arch. Toxicol. , vol.79 , pp. 427-433
- Arinç, E.¹ Arslan, S.² Adali, O.³

12
- 77951974693
- Ionnides C. Drug Metab. Rev. 25 (1993) 483-501
- (1993) Drug Metab. Rev. , vol.25 , pp. 483-501
- Ionnides, C.¹

13
- 77951976322
- Yang C.S., Hong J.Y., Ari{dotless}nç E., Schenkman J.B., and Hodgson E. (Eds), Springer-Verlag, Heidelberg
- In: Yang C.S., Hong J.Y., Ari{dotless}nç E., Schenkman J.B., and Hodgson E. (Eds). Molecular Aspects of Oxidative Drug Metabolizing Enzymes: Their Significance in Environmental Toxicology, Chemical Carcinogenesis and Health (1995), Springer-Verlag, Heidelberg 181-192
- (1995) Molecular Aspects of Oxidative Drug Metabolizing Enzymes: Their Significance in Environmental Toxicology, Chemical Carcinogenesis and Health , pp. 181-192

14
- 34547897290
- Ulusoy G., Ari{dotless}nç E., and Adali O. Arch. Toxicol. 81 (2007) 711-718
- (2007) Arch. Toxicol. , vol.81 , pp. 711-718
- Ulusoy, G.¹ Arinç, E.² Adali, O.³

15
- 19944434201
- Jin Y., Desta Z., Stearns V., Ward B., Ho H., Kyung-Hoon L., Skaar T., Storniolo A.M., Lang L., Araba A., Blanchard R., Nugyen A., Ullmer L., Hayden J., Lemler S., Weinshilboum R.M., Rae J.M., Hayes D.F., and Flockhard D.A. J. Natl. Cancer Inst. 97 (2005) 30-39
- (2005) J. Natl. Cancer Inst. , vol.97 , pp. 30-39
- Jin, Y.¹ Desta, Z.² Stearns, V.³ Ward, B.⁴ Ho, H.⁵ Kyung-Hoon, L.⁶ Skaar, T.⁷ Storniolo, A.M.⁸ Lang, L.⁹ Araba, A.¹⁰ Blanchard, R.¹¹ Nugyen, A.¹² Ullmer, L.¹³ Hayden, J.¹⁴ Lemler, S.¹⁵ Weinshilboum, R.M.¹⁶ Rae, J.M.¹⁷ Hayes, D.F.¹⁸ Flockhard, D.A.¹⁹

16
- 36849092797
- Desta Z., and Flockhart D.A. J. Clin. Pharmacol. 25 (2007) 5147-5149
- (2007) J. Clin. Pharmacol. , vol.25 , pp. 5147-5149
- Desta, Z.¹ Flockhart, D.A.²

17
- 0032819729
- Aynacioglu A.S., Brockmoller J., Bauer S., Sache C., Guzelbey P., Ongen Z., Nacak M., and Roots I. Br. J. Clin. Pharmacol. 48 (1999) 409-415
- (1999) Br. J. Clin. Pharmacol. , vol.48 , pp. 409-415
- Aynacioglu, A.S.¹ Brockmoller, J.² Bauer, S.³ Sache, C.⁴ Guzelbey, P.⁵ Ongen, Z.⁶ Nacak, M.⁷ Roots, I.⁸

18
- 0032772078
- Aynacioglu A.S., Sachse C., Bozkurt A., Kortunay S., Nacak M., Schroder T., Kayaalp S.O., Roots I., and Brockmoller J. Clin. Pharmacol. Ther. 66 (1999) 185-192
- (1999) Clin. Pharmacol. Ther. , vol.66 , pp. 185-192
- Aynacioglu, A.S.¹ Sachse, C.² Bozkurt, A.³ Kortunay, S.⁴ Nacak, M.⁵ Schroder, T.⁶ Kayaalp, S.O.⁷ Roots, I.⁸ Brockmoller, J.⁹

19
- 34249820794
- Koseler A., Ilkol Y.O., and Ulus I.H. Pharmacology 79 (2007) 203-206
- (2007) Pharmacology , vol.79 , pp. 203-206
- Koseler, A.¹ Ilkol, Y.O.² Ulus, I.H.³

20
- 37049014486
- Ulusoy G., Adali O., Tümer T.B., Şahin G., Gozdaşoglu S., and Ari{dotless}nç E. Oncology 72 (2007) 125-131
- (2007) Oncology , vol.72 , pp. 125-131
- Ulusoy, G.¹ Adali, O.² Tümer, T.B.³ Şahin, G.⁴ Gozdaşoglu, S.⁵ Arinç, E.⁶

21
- 34848878127
- Tümer T.B., Ulusoy G., Adali O., Şahin G., Gozdaşoglu S., and Ari{dotless}nç E. Am. J. Hematol. 82 (2007) 906-910
- (2007) Am. J. Hematol. , vol.82 , pp. 906-910
- Tümer, T.B.¹ Ulusoy, G.² Adali, O.³ Şahin, G.⁴ Gozdaşoglu, S.⁵ Arinç, E.⁶

22
- 0038048075
- Ari{dotless}nç E., Bozcaarmutlu A., and Biochem J. Mol. Toxicol. 17 (2003) 169-176
- (2003) Mol. Toxicol. , vol.17 , pp. 169-176
- Arinç, E.¹ Bozcaarmutlu, A.² Biochem, J.³

23
- 33845929539
- Akutsu T., Kobayashi K., Sakurada K., Ikegaya H., Furihata T., and Chiba K. Drug Metab. Dispos. 35 (2007) 72-78
- (2007) Drug Metab. Dispos. , vol.35 , pp. 72-78
- Akutsu, T.¹ Kobayashi, K.² Sakurada, K.³ Ikegaya, H.⁴ Furihata, T.⁵ Chiba, K.⁶

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.