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Volumn 82, Issue 10, 2007, Pages 906-910

The low frequency of defective TPMT alleles in Turkish population: A study on pediatric patients with acute lymphoblastic leukemia

Author keywords

[No Author keywords available]

Indexed keywords

MERCAPTOPURINE; THIOPURINE METHYLTRANSFERASE;

EID: 34848878127     PISSN: 03618609     EISSN: 10968652     Source Type: Journal    
DOI: 10.1002/ajh.20947     Document Type: Article
Times cited : (31)

References (35)
  • 1
    • 0030825783 scopus 로고    scopus 로고
    • Continuing (maintenance) therapy in lymphoblastic leukaemia: Lessons from MRC UKALL X. Medical Research Council Working Party in Childhood Leukaemia
    • Chessells JM, Harrison G, Lilleyman JS, et al. Continuing (maintenance) therapy in lymphoblastic leukaemia: Lessons from MRC UKALL X. Medical Research Council Working Party in Childhood Leukaemia. Br J Haematol 1997;98:945-951.
    • (1997) Br J Haematol , vol.98 , pp. 945-951
    • Chessells, J.M.1    Harrison, G.2    Lilleyman, J.S.3
  • 2
    • 0032545976 scopus 로고    scopus 로고
    • Conventional compared with individualized chemotherapy for childhood acute lymphoblastic leukemia
    • Evans WE, Relling MV, Rodman JH, et al. Conventional compared with individualized chemotherapy for childhood acute lymphoblastic leukemia. N Engl J Med 1998;338:499-505.
    • (1998) N Engl J Med , vol.338 , pp. 499-505
    • Evans, W.E.1    Relling, M.V.2    Rodman, J.H.3
  • 3
    • 0035056404 scopus 로고    scopus 로고
    • Thiopurine pharmacogenetics: Clinical and molecular studies of thiopurine methyltransferase
    • Weinshilboum R. Thiopurine pharmacogenetics: Clinical and molecular studies of thiopurine methyltransferase. Drug Metab Dispos 2001;29:601-605.
    • (2001) Drug Metab Dispos , vol.29 , pp. 601-605
    • Weinshilboum, R.1
  • 4
    • 0005454374 scopus 로고    scopus 로고
    • Genotypic and phenotypic analysis of the polymorphic thiopurine S-methyltransferase gene (TPMT) in a European population
    • Spire-Vayron de la Moureyre C, Debuysere H, Mastain B, Vinner E, Marez D, Lo Guidice JM, et al. Genotypic and phenotypic analysis of the polymorphic thiopurine S-methyltransferase gene (TPMT) in a European population. Br J Pharmacol 1998;125:879-887.
    • (1998) Br J Pharmacol , vol.125 , pp. 879-887
    • Spire-Vayron de la Moureyre, C.1    Debuysere, H.2    Mastain, B.3    Vinner, E.4    Marez, D.5    Lo Guidice, J.M.6
  • 5
    • 0020677815 scopus 로고
    • Assay of 6-thioguanine nucleotide, a major metabolite of azathioprine, 6-mercaptopurine and 6-thioguanine, in human red blood cells
    • Lennard L, Maddocks J. Assay of 6-thioguanine nucleotide, a major metabolite of azathioprine, 6-mercaptopurine and 6-thioguanine, in human red blood cells. J Pharm Pharmacol 1983;35:15-18.
    • (1983) J Pharm Pharmacol , vol.35 , pp. 15-18
    • Lennard, L.1    Maddocks, J.2
  • 6
    • 0018822866 scopus 로고
    • Mercaptopurine pharmacogenetics: Monogenic inheritance of erythrocyte thiopurine methyltransferase activity
    • Weinshilboum RM, Sladek SL. Mercaptopurine pharmacogenetics: Monogenic inheritance of erythrocyte thiopurine methyltransferase activity. Am J Hum Genet 1980;32:651-662.
    • (1980) Am J Hum Genet , vol.32 , pp. 651-662
    • Weinshilboum, R.M.1    Sladek, S.L.2
  • 8
    • 0033486029 scopus 로고    scopus 로고
    • Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus
    • Relling MV, Hancock ML, Rivera GK, et al. Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus. J Natl Cancer Inst 1999;91:2001-2008.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 2001-2008
    • Relling, M.V.1    Hancock, M.L.2    Rivera, G.K.3
  • 9
    • 2942532516 scopus 로고    scopus 로고
    • Translating pharmacogenetics and pharmacogenomics into drug development for clinical pediatrics and beyond
    • Leeder JS. Translating pharmacogenetics and pharmacogenomics into drug development for clinical pediatrics and beyond. Drug Discov Today 2004;9:567-573.
    • (2004) Drug Discov Today , vol.9 , pp. 567-573
    • Leeder, J.S.1
  • 10
    • 0030986251 scopus 로고    scopus 로고
    • Enhanced proteolysis of thiopurine S-methyltransferase (TPMT) encoded by mutant alleles in humans (TPMT*3A, TPMT*2): Mechanisms for the genetic polymorphism of TPMT activity
    • Tai HL, Krynetski EY, Schuetz EG, et al. Enhanced proteolysis of thiopurine S-methyltransferase (TPMT) encoded by mutant alleles in humans (TPMT*3A, TPMT*2): mechanisms for the genetic polymorphism of TPMT activity. Proc Natl Acad Sci USA 1997;94:6444-6449.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 6444-6449
    • Tai, H.L.1    Krynetski, E.Y.2    Schuetz, E.G.3
  • 11
    • 0030048791 scopus 로고    scopus 로고
    • Thiopurine methyltransferase pharmacogenetics: Human gene cloning and characterization of a common polymorphism
    • Szumlanski C, Otterness D, Her C, et al. Thiopurine methyltransferase pharmacogenetics: Human gene cloning and characterization of a common polymorphism. DNA Cell Biol 1996;15:17-30.
    • (1996) DNA Cell Biol , vol.15 , pp. 17-30
    • Szumlanski, C.1    Otterness, D.2    Her, C.3
  • 12
    • 0141564760 scopus 로고    scopus 로고
    • In vitro characterization of four novel non-functional variants of the thiopurine S-methyltransferase
    • Hamdan-Khalil R, Allorge D, Lo-Guidice JM, et al. In vitro characterization of four novel non-functional variants of the thiopurine S-methyltransferase. Biochem Biophys Res Commun 2003;309:1005-1010.
    • (2003) Biochem Biophys Res Commun , vol.309 , pp. 1005-1010
    • Hamdan-Khalil, R.1    Allorge, D.2    Lo-Guidice, J.M.3
  • 13
    • 11844274653 scopus 로고    scopus 로고
    • Identification and functional analysis of two rare allelic variants of the thiopurine S-methyltransferase gene, TPMT*6 and TPMT*19
    • Hamdan-Khalil R, Gala JL, Allorge D, et al. Identification and functional analysis of two rare allelic variants of the thiopurine S-methyltransferase gene, TPMT*6 and TPMT*19. Biochem Pharmacol 2005;69:525-529.
    • (2005) Biochem Pharmacol , vol.69 , pp. 525-529
    • Hamdan-Khalil, R.1    Gala, J.L.2    Allorge, D.3
  • 14
    • 33750581390 scopus 로고    scopus 로고
    • Three novel thiopurine S-methyltransferase allelic variants (TPMT*20, *21, *22) - Association with decreased enzyme function
    • Schaeffeler E, Eichelbaum M, Reinisch W, et al. Three novel thiopurine S-methyltransferase allelic variants (TPMT*20, *21, *22) - Association with decreased enzyme function. Hum Mutat 2006;27:976-983.
    • (2006) Hum Mutat , vol.27 , pp. 976-983
    • Schaeffeler, E.1    Eichelbaum, M.2    Reinisch, W.3
  • 15
    • 0030934850 scopus 로고    scopus 로고
    • Molecular diagnosis of thiopurine S-methyl transferase deficiency: Genetic basis for azathioprine and mercaptopurine intolerance
    • Yates CR, Krynetski EY, Loennechen T. Molecular diagnosis of thiopurine S-methyl transferase deficiency: Genetic basis for azathioprine and mercaptopurine intolerance. Ann Intern Med 1997;126:608-616.
    • (1997) Ann Intern Med , vol.126 , pp. 608-616
    • Yates, C.R.1    Krynetski, E.Y.2    Loennechen, T.3
  • 16
    • 0028861745 scopus 로고
    • A single point mutation leading to loss of catalytic activity in human thiopurine S-methyltransferase
    • Krynetski EY, Schuetz JD, Galpin AJ, et al. A single point mutation leading to loss of catalytic activity in human thiopurine S-methyltransferase. Proc Natl Acad Sci USA 1995;92:949-953.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 949-953
    • Krynetski, E.Y.1    Schuetz, J.D.2    Galpin, A.J.3
  • 17
    • 0031820555 scopus 로고    scopus 로고
    • Isolation of a human thiopurine S-methyltransferase (TPMT) complementary DNA with a single nucleotide transition A719G (TPMT*3C) and its association with loss of TPMT protein and catalytic activity in humans
    • Loennechen T, Yates CR, Fessing MY et al. Isolation of a human thiopurine S-methyltransferase (TPMT) complementary DNA with a single nucleotide transition A719G (TPMT*3C) and its association with loss of TPMT protein and catalytic activity in humans. Clin Pharmacol Ther 1998;64:46-51.
    • (1998) Clin Pharmacol Ther , vol.64 , pp. 46-51
    • Loennechen, T.1    Yates, C.R.2    Fessing, M.Y.3
  • 18
    • 0033027232 scopus 로고    scopus 로고
    • Analysis of thiopurine methyl-transferase variant alleles in childhood acute lymphoblastic leukaemia
    • McLeod HL, Coulthard S, Thomas AE, et al. Analysis of thiopurine methyl-transferase variant alleles in childhood acute lymphoblastic leukaemia. Br J Haematol 1999;105:696-700.
    • (1999) Br J Haematol , vol.105 , pp. 696-700
    • McLeod, H.L.1    Coulthard, S.2    Thomas, A.E.3
  • 19
    • 0032898097 scopus 로고    scopus 로고
    • Polymorphism of the thiopurine S-methyl-transferase gene in African-Americans
    • Hon YY, Fessing MY, Pui CH, et al. Polymorphism of the thiopurine S-methyl-transferase gene in African-Americans. Hum Mol Genet 1999;8:371-376.
    • (1999) Hum Mol Genet , vol.8 , pp. 371-376
    • Hon, Y.Y.1    Fessing, M.Y.2    Pui, C.H.3
  • 20
    • 0032898380 scopus 로고    scopus 로고
    • Thiopurine methyltransferase alleles in British and Ghanaian populations
    • Ameyaw MM, Collie-Duguid ES, Powrie RH, et al. Thiopurine methyltransferase alleles in British and Ghanaian populations. Hum Mol Genet 1999;8:367-370.
    • (1999) Hum Mol Genet , vol.8 , pp. 367-370
    • Ameyaw, M.M.1    Collie-Duguid, E.S.2    Powrie, R.H.3
  • 21
    • 0035036007 scopus 로고    scopus 로고
    • Genotype-phenotype correlation for thiopurine S-methyltransferase in healthy Italian subjects
    • Rossi AM, Bianchi M, Guarnieri C, et al. Genotype-phenotype correlation for thiopurine S-methyltransferase in healthy Italian subjects. Eur J Clin Pharmacol 2001;57:51-54.
    • (2001) Eur J Clin Pharmacol , vol.57 , pp. 51-54
    • Rossi, A.M.1    Bianchi, M.2    Guarnieri, C.3
  • 22
    • 0034646283 scopus 로고    scopus 로고
    • Genetic analysis of thiopurine methyltransferase polymorphism in a Japanese population
    • Hiratsuka M, Inoue T, Omori F, et al. Genetic analysis of thiopurine methyltransferase polymorphism in a Japanese population. Mutat Res 2000;448:91-95.
    • (2000) Mutat Res , vol.448 , pp. 91-95
    • Hiratsuka, M.1    Inoue, T.2    Omori, F.3
  • 23
    • 0036260109 scopus 로고    scopus 로고
    • Molecular analysis of thiopurine S-methyl-transferase alleles in South-east Asian populations
    • Chang JG, Lee LS, Chen CM, et al. Molecular analysis of thiopurine S-methyl-transferase alleles in South-east Asian populations. Pharmacogenetics 2002;12:191-195.
    • (2002) Pharmacogenetics , vol.12 , pp. 191-195
    • Chang, J.G.1    Lee, L.S.2    Chen, C.M.3
  • 24
    • 0036066914 scopus 로고    scopus 로고
    • Thiopurine methyltransferase polymorphisms in a multiracial Asian population and children with acute lymphoblastic leukemia
    • Kham SK, Tan PL, Tay AH, et al. Thiopurine methyltransferase polymorphisms in a multiracial Asian population and children with acute lymphoblastic leukemia. J Pediatr Hematol Oncol 2002;24:353-359.
    • (2002) J Pediatr Hematol Oncol , vol.24 , pp. 353-359
    • Kham, S.K.1    Tan, P.L.2    Tay, A.H.3
  • 26
    • 0141792487 scopus 로고    scopus 로고
    • Allelic variants of the thiopurine methyltransferase (TPMT) gene in the Colombian population
    • Isaza C, Henao J, Lopez AM, Cacabelos R. Allelic variants of the thiopurine methyltransferase (TPMT) gene in the Colombian population. Methods Find Exp Clin Pharmacol 2003;25:423-429.
    • (2003) Methods Find Exp Clin Pharmacol , vol.25 , pp. 423-429
    • Isaza, C.1    Henao, J.2    Lopez, A.M.3    Cacabelos, R.4
  • 27
    • 3843129809 scopus 로고    scopus 로고
    • Phenotyping and genotyping study of thiopurine S-methyltransferase in healthy Chinese children: A comparison of Han and Yao ethnic groups
    • Zhang JP, Guan YY, Wu JH, et al. Phenotyping and genotyping study of thiopurine S-methyltransferase in healthy Chinese children: A comparison of Han and Yao ethnic groups. Br J Clin Pharmacol 2004;58:163-168.
    • (2004) Br J Clin Pharmacol , vol.58 , pp. 163-168
    • Zhang, J.P.1    Guan, Y.Y.2    Wu, J.H.3
  • 28
    • 25144516544 scopus 로고    scopus 로고
    • Phenotyping and genotyping studies of thiopurine S-methyltransferase in Kazaks
    • Wei H, Zhou S, Li C, et al. Phenotyping and genotyping studies of thiopurine S-methyltransferase in Kazaks. Pharm Res 2005;22:1762-1766.
    • (2005) Pharm Res , vol.22 , pp. 1762-1766
    • Wei, H.1    Zhou, S.2    Li, C.3
  • 29
    • 0033434009 scopus 로고    scopus 로고
    • Ethnic differences in thiopurine methyltransferase pharmacogenetics: Evidence for allele specificity in Caucasian and Kenyan individuals
    • McLeod HL, Pritchard SC, Githang J, et al. Ethnic differences in thiopurine methyltransferase pharmacogenetics: Evidence for allele specificity in Caucasian and Kenyan individuals. Pharmacogenetics 1999;9:773-776.
    • (1999) Pharmacogenetics , vol.9 , pp. 773-776
    • McLeod, H.L.1    Pritchard, S.C.2    Githang, J.3
  • 30
    • 4444268912 scopus 로고    scopus 로고
    • Tracing the origin of the most common thiopurine methyltransferase (TPMT) variants: Preliminary data from the patterns of haplotypic association with two CA repeats
    • Alves S, Rocha J, Amorim A, Prata MJ. Tracing the origin of the most common thiopurine methyltransferase (TPMT) variants: Preliminary data from the patterns of haplotypic association with two CA repeats. Ann Hum Genet 2004;68:313-323.
    • (2004) Ann Hum Genet , vol.68 , pp. 313-323
    • Alves, S.1    Rocha, J.2    Amorim, A.3    Prata, M.J.4
  • 31
    • 2942522714 scopus 로고    scopus 로고
    • Polymorphisms of cytochrome P450 1A1, gluthatione S-transferases M1 and T1 in a Turkish population
    • Ada AO, Süzen SH, Iscan M. Polymorphisms of cytochrome P450 1A1, gluthatione S-transferases M1 and T1 in a Turkish population. Toxicol Lett 2004;151:311-315.
    • (2004) Toxicol Lett , vol.151 , pp. 311-315
    • Ada, A.O.1    Süzen, S.H.2    Iscan, M.3
  • 32
    • 0032819729 scopus 로고    scopus 로고
    • Frequency of cytochrome P4502C9 variants in a Turkish population and functional relevance for Phenytoin
    • Aynacioglu AS, Brockmoller J, Bauer S, et al. Frequency of cytochrome P4502C9 variants in a Turkish population and functional relevance for Phenytoin. Br J Clin Pharmacol 1999;48:409-415.
    • (1999) Br J Clin Pharmacol , vol.48 , pp. 409-415
    • Aynacioglu, A.S.1    Brockmoller, J.2    Bauer, S.3
  • 33
    • 34848905242 scopus 로고    scopus 로고
    • CYP2E1 genotyping in Turkish population: Determination of CYP2E17z.ast;5B, *6 and *7B alleles
    • Ulusoy G, Arinç E, Adali O. CYP2E1 genotyping in Turkish population: Determination of CYP2E17z.ast;5B, *6 and *7B alleles. Drug Metab Rev 2005;37:349.
    • (2005) Drug Metab Rev , vol.37 , pp. 349
    • Ulusoy, G.1    Arinç, E.2    Adali, O.3
  • 34
    • 0037969835 scopus 로고    scopus 로고
    • Characterization of MHTFR, GSTM1, GSTT1, GSTP1, and CYP1A1 Genotypes in childhood acute leukemia
    • Balta G, Yuksek N, Ozyurek E, et al. Characterization of MHTFR, GSTM1, GSTT1, GSTP1, and CYP1A1 Genotypes in childhood acute leukemia. Am J Hematol 2003;73:154-160.
    • (2003) Am J Hematol , vol.73 , pp. 154-160
    • Balta, G.1    Yuksek, N.2    Ozyurek, E.3
  • 35
    • 0027515695 scopus 로고
    • 2, EDTA, storage time, and temperature on DNA yield and quality
    • 2, EDTA, storage time, and temperature on DNA yield and quality. Biochem Genet 1993;31:321-328.
    • (1993) Biochem Genet , vol.31 , pp. 321-328
    • Lahiri, D.1    Schnabel, B.2


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