Polymorphisms and functional differences in aryl hydrocarbon receptors (AhR) in Japanese field mice, Apodemus speciosus

Environmental Toxicology and Pharmacology

Volumn 29, Issue 3, 2010, Pages 280-289

  Ishiniwa, Hiroko ^a   Sogawa, Kazuhiro ^b   Yasumoto, Ken ichi ^b   Sekijima, Tsuneo ^a  

^a NIIGATA UNIVERSITY   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

Author keywords

Apodemus speciosus; Aryl hydrocarbon receptor; Dioxin; DNA polymorphism; Gene environment interaction; Genetic variation; Japanese field mouse

Indexed keywords

AMINO ACID; ARGININE; AROMATIC HYDROCARBON RECEPTOR; BETA ACTIN; CYTOCHROME P450 1A1; DIOXIN; DNA; GLUTAMINE;

ALLELE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL STRAIN COS7; CONTROLLED STUDY; DNA SEQUENCE; GENE MUTATION; GENETIC POLYMORPHISM; GENETIC TRANSFECTION; HELA CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOBLOTTING; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSITIVITY ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; TOXICITY;

APODEMUS SPECIOSUS; MUS;

EID: 77951974198     PISSN: 13826689     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.etap.2010.03.006     Document Type: Article

References (55)

1. Baba T., Mimura J., Nakamura N., Harada N., Yamamoto M., Morohashi K., Fujii-Kuriyama Y. Intrinsic function of the aryl hydrocarbon (dioxin) receptor as a key factor in female reproduction. Mol. Cell. Biol. 2005, 25:10040-10051.
2. Bello S.M., Franks D.G., Stegeman J.J., Hahn M.E. Acquired resistance to Ah receptor agonists in a population of Atlantic Killifish (Fundulus heteroclitus) inhabiting a marine superfund site: in vivo and in vitro studies on the inducibility of xenobiotic metabolizing enzymes. Toxicol. Sci. 2001, 60:77-91.
3. Bromham L., Rambaut A., Harvey P.H. Determinants of rate variation in mammalian DNA sequence evolution. J. Mol. Evol. 1996, 43:610-621.
4. Choi J.S., Kim I.W., Hwang S.Y., Shin B.J., Kim S.K. Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on testicular spermatogenesis-related panels and serum sex hormone levels in rats. BJU Int. 2008, 101:250-255.
5. Cummings C.J., Zoghbi H.Y. Trinucleotide repeats: mechanisms and pathophysiology. Annu. Rev. Genomics Hum. Genet. 2000, 1:281-328.
6. DDBJ, 2010. http://www.ddbj.nig.ac.jp/index-e.html.
7. Ema M., Sogawa K., Watanabe N., Chujoh Y., Matsushita N., Gotoh O., Funae Y., Fujii-Kuriyama Y. cDNA cloning and structure of mouse putative Ah receptor. Biochem. Biophys. Res. Commun. 1992, 184:246-253.
8. Ema M., Ohe N., Suzuki M., Mimura J., Sogawa K., Ikawa S., Fujii-Kuriyama Y. Dioxin binding activities of polymorphic forms of mouse and human arylhydrocarbon receptors. J. Biol. Chem. 1994, 269:27337-27343.
9. Enan E., Overstreet J.W., Matsumura F., VandeVoort C.A., Lasley B.L. Gender differences in the mechanism of dioxin toxicity in rodents and in nonhuman primates. Reprod. Toxicol. 1996, 10:401-411.
10. Fukunaga B.N., Hankinson O. Identification of a novel domain in the aryl hydrocarbon receptor required for DNA binding. J. Biol. Chem. 1996, 271:3743-3749.
11. Fukuzawa N.H., Ohsako S., Wu Q., Sakaue M., Fujii-Kuriyama Y., Baba T., Tohyama C. Testicular cytochrome P450scc and LHR as possible targets of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the mouse. Mol. Cell. Endochrinol. 2004, 221:87-96.
12. Giwercman A., Rylander L., Rignell-Hydbom A., Jönsson B.A.G., Pedersen H.S., Ludwicki J.K., Lesovoy V., Zvyezday V., Spano M., Manicardi G.C., Bizzaro D., Bonefeld-Jørgensen E.C., Toft G., Bonde J.P., Giwercman C., Tiido T., Giwercman Y.L. Androgen receptor gene CAG repeat length as a modifier of the association between persistent organohalogen pollutant exposure markers and semen characteristics. Pharmacogenet. Genomics 2007, 17:391-401. INUENDO.
13. Graham F.L., van der Eb A.J. A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology 1973, 52:456-467.
14. Hahn M.E. Aryl hydrocarbon receptors: diversity and evolution. Chem. Biol. Interact. 2002, 141:131-160.
15. Hahn M.E., Karchner S.I., Franks D.G., Merson R.R. Aryl hydrocarbon receptor polymorphisms and dioxin resistance in Atlantic killifish (Fundulus heteroclitus). Pharmacogenetics 2004, 14:131-143.
16. Harper P.A., Wong J.M.Y., Lam M.S.M., Okey A.B. Polymorphisms in the human AH receptor. Chem. Biol. Interact. 2002, 141:161-187.
17. Hikida T., Murakami O. Age determination of the Japanese wood mouse, Apodemus speciosus. Jpn. J. Ecol. 1980, 30:109-116. (in Japanese).
18. 2 progeny. Toxicol. Appl. Pharmacol. 2005, 206:351-355.
19. Ishihara K., Warita K., Tanida T., Sugawara T., Kitagawa H., Hoshi N. Does paternal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) affect the sex ratio of offspring?. J. Vet. Med. Sci. 2007, 69:347-352.
20. Karchner S.I., Franks D.G., Kennedy S.W., Hahn M.E. The molecular basis for differential dioxin sensitivity in birds: role of the aryl hydrocarbon receptor. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:6252-6257.
21. Kim D.W., Gazourian L., Quadri S.A., Romieu-Mourez R., Sherr D.H., Sonenshein G.E. The RelA NF-κB subunit and the aryl hydrocarbon receptor (AhR) cooperate to transactivate the c-myc promoter in mammary cells. Oncogene 2000, 19:5498-5506.
22. Kleeman J.M., Olson J.R., Peterson R.E. Species differences in 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity and biotransformation in fish. Fundam. Appl. Toxicol. 1988, 10:206-213.
23. Ko H.P., Okino S.T., Ma Q., Whitlock J.P. Transactivation domains facilitate promoter occupancy for the dioxin-inducible CYP1A1 gene in vivo. Mol. Cell. Biol. 1997, 17:3497-3507.
24. Kumar M.B., Ramadoss P., Reen R.K., Vanden-Heuvel J.P., Perdew G.H. The Q-rich subdomain of the human Ah receptor transactivation domain is required for dioxin-mediated transcriptional activity. J. Biol. Chem. 2001, 276:42302-42310.
25. Kyoya T., Obara Y., Nakata A. Chromosomal aberrations in Japanese grass voles in and around an illegal dumpsite at the Aomori-Iwate prefectural boundary. Zool. Sci. 2008, 25:307-312.
26. Latchoumycandane C., Chitra K.C., Mathur P.P. Induction of oxidative stress in rat epididymal sperm after exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Arch. Toxicol. 2002, 76:113-118.
27. Li W.H., Ellsworth D.L., Krushkal J., Chang B.H.J., Hewett-Emmett D. Rates of nucleotide substitution in primates and rodents and the generation-time effect hypothesis. Mol. Phylogenet. Evol. 1996, 5:182-187.
28. Matsumura F. On the significance of the role of cellular stress response reactions in the toxic actions of dioxin. Biochem. Pharmacol. 2003, 66:527-540.
29. Matsumura F. The significance of the nongenomic pathway in mediating inflammatory signaling of the dioxin-activated Ah receptor to cause toxic effects. Biochem. Pharmacol. 2009, 77:608-626.
30. Matsushita N., Sogawa K., Ema M., Yoshida A., Fujii-Kuriyama Y. A factor binding to the xenobiotic responsive element (XRE) of P-4501A1 gene consists of at least two helix-loop-helix proteins, Ah receptor and Arnt. J. Biol. Chem. 1993, 268:21002-21006.
31. Mimura J., Ema M., Sogawa K., Fujii-Kuriyama Y. Identification of a novel mechanism of regulation of Ah (dioxin) receptor function. Genes Dev. 1999, 13:20-25.
32. Mizushima S., Nagata S. pEF-BOS, a powerful mammalian expression vector. Nucleic Acids Res. 1990, 18:5322.
33. Morel Y., Barouki R. Down-regulation of cytochrome P450 1A1 gene promoter by oxidative stress. J. Biol. Chem. 1998, 273:26969-26976.
34. Murata M., Iseki N., Masunaga S., Nakanishi J. Estimation of effects of dioxins and dioxin-like PCBs on wildlife population-a case study on common cormorant. Chemosphere 2003, 53:337-345.
35. Newton C.R. Mutational analysis: known mutations. PCR 2: A Practical Approach 1995, 219-254. Oxford University Press Inc., New York. M.J. McPherson, B.D. Hames, G.R. Taylor (Eds.).
36. Oh H.S., Mori T. Growth, development and reproduction in captive of the large Japanese field mouse, Apodemus speciosus (Rodentia, Muridae). J. Fac. Agric. Kyusyu Univ. 1998, 43:397-408.
37. Ohtake F., Takeyama K., Matsumoto T., Kitagawa H., Yamamoto Y., Nohara K., Tohyama C., Krust A., Mimura J., Chambon P., Yanagisawa J., Fujii-Kuriyama Y., Kato S. Modulation of oestrogen receptor signalling by association with the activated dioxin receptor. Nature 2003, 423:545-550.
38. Ohtake F., Baba A., Takada I., Okada M., Iwasaki K., Miki H., Takahashi S., Kouzmenko A., Nohara K., Chiba T., Fujii-Kuriyama Y., Kato S. Dioxin receptor is a ligand-dependent E3 ubiquitin ligase. Nature 2007, 446:562-566.
39. Ovando B.J., Vezina C.M., McGarrigle B.P., Olson J.R. Hepatic gene downregulation following acute and subchronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol. Sci. 2006, 94:428-438.
40. Pohjanvirta R., Tuomisto J. Short-term toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in laboratory animals: effects, mechanisms, and animal models. Pharmacol. Rev. 1994, 46:483-549.
41. Pohjanvirta R., Unkila M., Tuomisto J. Comparative acute lethality of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), 1,2,3,7,8-pentachlorodibenzo-p-dioxin and 1,2,3,4,7,8-hexachlorodibenzo-p-dioxin in the most TCDD-susceptible and the most TCDD-resistant rat strain. Pharmacol. Toxicol. 1993, 73:52-56.
42. Pohjanvirta R., Wong J.M.Y., Li W., Harper P.A., Tuomisto J., Okey A.B. Point mutation in intron sequence causes altered carboxyl-terminal structure in the aryl hydrocarbon receptor of the most 2,3,7,8-tetrachlorodibenzo-p-dioxin-resistant rat strain. Mol. Pharmacol. 1998, 54:86-93.
43. Poland A., Knutson J.C. 2,3,7,8-tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: examination of the mechanism of toxicity. Annu. Rev. Pharmacol. Toxicol. 1982, 22:517-554.
44. Puga A., Xia Y., Elferink C. Role of the aryl hydrocarbon receptor in cell cycle regulation. Chem. Biol. Interact. 2002, 141:117-130.
45. Rowlands J.C., McEwan I.J., Gustafsson J.A. Trans-activation by the human aryl hydrocarbon receptor and aryl hydrocarbon receptor nuclear translocator proteins: direct interactions with basal transcription factors. Mol. Pharmacol. 1996, 50:538-548.
46. Sambrook J., Fritsch E.F., Maniatis T. Molecular Cloning: A Laboratory Manual 1989, Cold Spring Harbor Laboratory Press, New York. second ed.
47. Senft A.P., Dalton T.P., Nebert D.W., Genter M.B., Puga A., Hutchinson R.J., Kerzee J.K., Uno S., Shertzer H.G. Mitochondrial reactive oxygen production is dependent on the aromatic hydrocarbon receptor. Free Radic. Biol. Med. 2002, 33:1268-1278.
48. Silkworth J.B., Carlson E.A., McCulloch C., Illouz K., Goodwin S., Sutter T.R. Toxicogenomic analysis of gender, chemical, and dose effects in livers of TCDD- or aroclor 1254-exposed rats using a multifactor linear model. Toxicol. Sci. 2008, 102:291-309.
49. Slezak B.P., Hatch G.E., DeVito M.J., Diliberto J.J., Slade R., Crissman K., Hassoun E., Birnbaum L.S. Oxidative stress in female B6C3F1 mice following acute and subchronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Toxicol. Sci. 2000, 54:390-398.
50. Sogawa K., Fujii-Kuriyama Y. Ah receptor, a novel ligand-activated transcription factor. J. Biochem. 1997, 122:1075-1079.
51. Sun W., Zhang J., Hankinson O. A mutation in the aryl hydrocarbon receptor (AHR) in a cultured mammalian cell line identifies a novel region of AHR that affects DNA binding. J. Biol. Chem. 1997, 272:31845-31854.
52. Takahata S., Sogawa K., Kobayashi A., Ema M., Mimura J., Ozaki N., Fujii-Kuriyama Y. Transcriptionally active heterodimer formation of an Arnt-like PAS protein, Arnt3, with HIF-1a, HLF, and clock. Biochem. Biophys. Res. Commun. 1998, 248:789-794.
53. Takahata S., Ozaki T., Mimura J., Kikuchi Y., Sogawa K., Fujii-Kuriyama Y. Transactivation mechanisms of mouse clock transcription factors, mClock and mArnt3. Genes Cells 2000, 5:739-747.
54. Thomas R.S., Penn S.G., Holden K., Bradfield C.A., Rank D.R. Sequence variation and phylogenetic history of the mouse Ahr gene. Pharmacogenetics 2002, 12:151-163.
55. Yasuda M., Yamada F., Kawaji N., Okochi I., Yamazaki K., Nakajima M., Ishizuka T., Takasuga T., Kumar K.S. Concentration of POPs in wildlife from central Japan. Abstracts of 12th Symposium on Environmental Chemistry 2003, 448-449. (in Japanese).