Oxidative stress in female B6C3F1 mice following acute and subchronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)

Toxicological Sciences

Volumn 54, Issue 2, 2000, Pages 390-398

  Slezak, B P ^a   Hatch, G E ^b   DeVito, M J ^b,d   Diliberto, J J ^b   Slade, R ^b   Crissman, K ^b   Hassoun, E ^c   Birnbaum, L S ^b  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^c UNIVERSITY OF TOLEDO   (United States)

^d U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Oxidative stress; Reactive oxygen species (ROS); TCDD

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; CYTOCHROME C; GLUTATHIONE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; KIDNEY; LIVER; LONG TERM EXPOSURE; METABOLISM; MOUSE; NONHUMAN; OXIDATIVE STRESS; REDUCTION; SPLEEN;

ANIMALIA;

EID: 0034111051     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/54.2.390     Document Type: Article

References (41)

1. Alsharif, N. Z., Lawson, T., and Stohs, S. J. (1994a). Oxidative stress induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin is mediated by the aryl hydrocarbon (Ah) receptor complex. Toxicology 92, 39-51.
2. Alsharif, N. Z., Schlueter, W. J., and Stohs, S. J. (1994b). Stimulation of NADPH-dependent reactive oxygen species formation and DNA damage by 2,3,7,8-tetrachlorodibenzo-p-dioxin in rat peritoneal lavage cells. Arch. Environ. Contam. Toxicol. 26, 392-397.
3. Anderson, M. E. (1985). Determination of glutathione and glutathione disulfide in biological samples. Methods Enzym. 113, 548-555.
4. Anundi, I., Hogberg, J., and Stead, A. H. (1979). Glutathione depletion in isolated hepatocytes: its relations to lipid peroxidation and cell damage. Acta Pharmacol. Toxicol. (Copenh.) 45, 45-51.
5. Ashida, H., Enan, E., and Matsumura, F. (1996). Protective action of dehydroascorbic acid on the Ah receptor-dependent and receptor-independent induction of lipid peroxidation in adipose tissue of male guinea pig caused by TCDD administration. J. Biochem. Toxicol. 11, 269-278.
6. Babior, B. M., Kipner, R. S., and Curnutte, J. T. (1973). Biological defense mechanisms. The production by leukocytes of superoxide, a potential bactericidal agent. J. Clin. Invest., 52, 741-744.
7. Birnbaum, L. S. (1994). The mechanism of dioxin toxicity: relationship to risk assessment. Environ. Health Perspect. 102, 157-167.
8. Bondy, S. C., and Naderi, S. (1994). Contribution of hepatic cytochrome P450 systems to the generation of reactive oxygen species. Biochem. Pharmacol. 48, 155-159.
9. Bradford, M. M. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
10. Comporti, M., Maellaro, E., Del Bello, B., and Casini, A. F. (1991). Glutathione depletion: Its effects on other antioxidant systems and hepatocellular damage. Xenobiotica 21, 1067-1076.
11. DeVito, M. J., Birnbaum, L. S., Farland, W. H., and Gasiewicz., T. A. (1995). Comparisons of estimated human body burdens of dioxinlike chemicals and TCDD body burdens in experimentally exposed animals. Environ. Health Perspect. 103, 820-831.
12. Diliberto, J. J., Akubue, P. I., Luebke, R. W., and Birnbaum, L. S. (1995). Dose-response relationships of tissue distribution and induction of CYP1A1 and Cyp1A2 enzymatic activities following acute exposure to 2,3,7,8-tetrachlordibenzo-p-dioxin in mice. Toxicol. Appl. Pharmacol. 130, 197-208.
13. Ghio, A. J., Kennedy, T. P., Crissman, K. M., Richards, J. H., and Hatch, G. E. (1998). Depletion of iron and ascorbate in rodents diminishes lung injury after silica. Exp. Lung Res. 24, 219-232.
14. Ghio, A. J., Kennedy, T. P., Hatch, G. E., and Tepper, J. S. (1991). Reduction of neutrophil influx diminishes lung injury and mortality following phosgene inhalation. J. Appl. Physiol. 71, 657-665.
15. Guengerich, F. P., and Liebler, D. C. (1985). Enzymatic activation of chemicals to toxic metabolites. Crit. Rev. Toxicol. 14, 259-307.
16. Hassan, M. Q., Stohs, S. J., and Murray, W. (1983). Comparative ability to TCDD to induce lipid peroxidation in rats, guinea pigs, and syrian golden hamsters. Bull. Environ. Contam. Toxicol. 31, 649-657.
17. Hassan, M. Q., Stohs, S. J., Murray, W. J., and Birt, D. F. (1985). Dietary selenium, glutathione peroxidase activity, and toxicity of 2,3,7,8-tetrachlordibenzo-p-dioxin. J. Toxicol. Environ. Health 15, 405-415.
18. Hassoun, E. A., Bagchi, D., and Stohs, S. J. (1996). TCDD, endrin, and lindane induced increases in lipid metabolites in maternal sera and amniotic fluids of pregnant C57BL/6J and DBA/2J mice. Res. Comm. Mol. Pathol. Pharmacol. 94, 157-169.
19. Hassoun, E. A., Wilt, S. C., DeVito, M. J., Van Birgelen, A., Alsharif, N. Z., Birnbaum, L. S., and Stohs, S. J. (1998). Induction of oxidative stress in brain tissues of mice after subchronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol. Sci. 42, 23-27.
20. Hurst, C. H., Abbott, B. D., DeVito, M. J., and Birnbaum, L. S. (1998). 2,3,7,8-tetrachlorodibenzo-p-dioxin in pregnant Long Evans rats: disposition to maternal and embryo/fetal tissues. Toxicol. Sci. 45, 129-136.
21. Ingelman-Sundberg, M., and Johansson, I. (1984). Mechanisms of hydroxyl radical formation and ethanol oxidation by ethanol-inducible and other forms of rabbit liver microsomal cytochrome P-450. J. Biol. Chem. 259, 6447-6458.
22. Jackson, J. A., Birnbaum, L. S., and Diliberto, J. J. (1998). Effects of age, sex and pharmacologic agents on the biliary elimination of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in F344 rats. Drug Metab. Dispos. 26, 714-719.
23. Kuthan, H., and Ullrich, V. (1982). Oxidase and oxygenase function of the microsomal cytochrome P450 monooxygenase system. Eur. J. Biochem. 126, 583-588.
24. Mitchell, J. R., and Jollows, D. J. (1975). Progress in hepatology. Metabolic activation of drugs to toxic substances. Gastroenterology 68, 392-410.
25. Morehouse, L. A., and Aust, S. D. (1988). Generation of superoxide by the microsomal mixed-function oxidase system. Basic Life Sci. 49, 517-521.
26. Muhammadpour, H., Murray, W. J., and Stohs, S. J. (1988). 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced lipid peroxidation in genetically responsive and non-responsive mice. Arch. Environ. Contam. Toxicol. 16, 645-650.
27. Narasimhan, T. R., Craig, A., Arellano, L., Harper, N., Howie, L., Menache, M., Birnbaum, L., and Safe, S. (1994). Relative sensitivities of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced Cyp1a-1 and Cyp1a-2 gene expression and immunotoxicity in female B6C3F1 mice. Fundam. Appl. Toxicol. 23, 598-607.
28. Nebert, D. W., Puga, A., and Vasiliou, V. (1993). Role of the Ah receptor and the dioxin-inducible [Ah] gene battery in toxicity, cancer, and signal transduction. Ann. N.Y. Acad. Sci. 685, 624-640.
29. Park, J. Y., Shigenaga, M. K., and Ames, B. N. (1996). Induction of cytochrome P4501A1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin or indolo(3,2-b)-carbazole is associated with oxidative DNA damage. Proc. Natl. Acad. Sci. 93, 2322-2327.
30. Poulos, T. L., and Raag, R. (1992). Cytochrome P450cam: crystallography, oxygen activation, and electron transfer. FASEB J. 6, 674-679.
31. Safe, S. H. (1994). Polychlorinated biphenyls (PCBs): environmental impact, biochemical and toxic responses, and implications for risk assessment. Crit. Rev. Toxicol. 24, 87-149.
32. Santostefano, M. J., Wang, X., Richardson, V. M., Ross, D. G., DeVito, M. J., and Birnbaum, L. S. (1998). A pharmacodynamic analysis of TCDD-induced cytochrome P-450 gene expression in multiple tissues: dose- and time-dependent effects. Toxicol. Appl. Pharmacol. 151, 294-310.
33. Shertzer, H. G., Nebert, D. W., Puga, A., Ary, M., Sonntag, D., Dixon, K., Robinson, L. J., Cianciolo, E., and Dalton, T. P. (1998). Dioxin causes a sustained oxidative stress response in the mouse. Biochem. Biophys. Res. Commun. 253, 44-48.
34. Smith, A. G., Clothier, B., Robinson, S., Scullion, M. J., Carthew, P., Edwards, R., Luo, J., Lim, C. K., and Toledano, M. (1998). Interaction between iron metabolism and 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice with variants of the Ahr gene: A hepatic oxidative mechanism. Mol. Pharmacol. 53, 52-61.
35. Stohs, S. J. (1990). Oxidative stress induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Free Radic. Biol. Med. 9, 79-90.
36. Stohs, S. J., Hassan, M. Q., and Murray, W. J. (1984a). Induction of lipid peroxidation and inhibition of glutathione peroxidase by TCDD. Branbury Report, Branbury Center, Cold Spring Harbor Laboratory 18, 241-253.
37. Stohs, S. J., Hassan, M. Q., and Murray, W. J. (1984b). Effects of BHA, d-α-tocopherol and retinol acetate on TCDD-mediated changes in lipid peroxidation, glutathione peroxidase activity and survival. Xenobiotica 14, 533-537.
38. Tritscher, A. M., Goldstein, J. A., Portier, C. J., McCoy, Z., Clark, G. C., and Lucier, G. W. (1992). Dose-response relationships for chronic exposure to 2,3,7,8-tetrachlordibenzo-p-dioxin in a rat tumor promotion model: Quantification and immunolocalization of CYP1A1 and CYP1A2 in the liver. Cancer Res. 52, 3436-3442.
39. Tritscher, A. M., Seacat, A. M., Yager, J. D., Groopman, J. D., Miller, B. D., Bell, D., Sutter, T. R., and Lucier, G. W. (1996). Increased oxidative DNA damage in livers of 2,3,7,8-tetrachlorodibenzo-p-dioxin treated intact but not ovariectomized rats. Cancer Lett. 98, 219-225.
40. Viluksela, M., Stahl, B. U., and Rozman, K. K. (1995). Tissue-specific effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the activity of phosphoenolpyruvate carboxykinase (PEPCK) in rats. Toxicol. Appl. Pharmacol. 135, 308-315.
41. Walker, N. J., Portier, C. J., Lax, S. F., Crofts, F. G., Li, Y., Lucier, G. W., and Sutter, T. R. (1999). Characterization of the dose-response of CYP1B1, CYP1A1, and CYP1A2 in the liver of female Sprague-Dawley rats following chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol. Appl. Pharmacol. 154, 279-286.