Reactive oxygen species produced by the knockdown of manganese-superoxide dismutase up-regulate hypoxia-inducible factor-1α expression in oral squamous cell carcinoma cells

Free Radical Biology and Medicine

Volumn 48, Issue 10, 2010, Pages 1321-1329

  Sasabe, Eri ^a   Yang, Zhu ^a   Ohno, Seiji ^a   Yamamoto, Tetsuya ^a  

^a KOCHI UNIVERSITY   (Japan)

Author keywords

Hypoxia inducible factor 1 ; Manganese superoxide dismutase; Oral squamous cell carcinoma; Reactive oxygen species

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; VON HIPPEL LINDAU PROTEIN;

ARTICLE; CANCER CELL; CELL HYPOXIA; CONTROLLED STUDY; GENE SILENCING; HUMAN; HUMAN CELL; INTERNAL RIBOSOME ENTRY SITE; MOUTH CARCINOMA; ORAL SQUAMOUS CELL CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; UBIQUITINATION; UPREGULATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CARCINOMA, SQUAMOUS CELL; CELL HYPOXIA; CELL LINE, TUMOR; EUKARYOTIC INITIATION FACTOR-4E; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MOUTH NEOPLASMS; PHOSPHOPROTEINS; PROTEIN BINDING; REACTIVE OXYGEN SPECIES; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE; TRANSCRIPTIONAL ACTIVATION; UBIQUITINATION; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;

MAMMALIA;

EID: 77951938912     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2010.02.013     Document Type: Article

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