A novel category of anti-hypertensive drugs for treating salt-sensitive hypertension on the basis of a new development concept

Pharmaceuticals

Volumn 3, Issue 1, 2010, Pages 59-109

  Katori, Makoto ^a   Majima, Masataka ^a  

^a KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

ATP sensitive potassium channel; Poststatin ebelactone B; Renal kallikrein; Salt sensitive hypertension

Indexed keywords

ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL BLOCKER; ANTIHYPERTENSIVE AGENT; BRADYKININ B2 RECEPTOR; BRADYKININ RECEPTOR; CAPTOPRIL; CARBOXYPEPTIDASE Y LIKE EXOPEPTIDASE; CHLORIDE ION; DILTIAZEM; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; EBELACTONE B; EXOPEPTIDASE; FUROSEMIDE; GLIBENCLAMIDE; HYDROCHLOROTHIAZIDE; KALLIKREIN; KALLIKREIN INHIBITOR; KININ; KININASE; LOW MOLECULAR WEIGHT KININOGEN; MEMBRANE METALLOENDOPEPTIDASE; N (1 ADAMANTYL) N' CYCLOHEXYL 4 MORPHOLINECARBOXAMIDINE; PLASMA KALLIKREIN; POTASSIUM; POTASSIUM CHANNEL BLOCKING AGENT; PROSTSTATIN; SODIUM; SODIUM CHLORIDE; TISSUE KALLIKREIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANGIOGENESIS; CELL MEMBRANE DEPOLARIZATION; DAHL SALT SENSITIVE RAT; DISEASE MODEL; DIURESIS; DRUG MECHANISM; DRUG SELECTIVITY; ERYTHROCYTE; GENE THERAPY; HEART MUSCLE ISCHEMIA; HENLE LOOP; HUMAN; HYPERTENSION; INTIMA; ISCHEMIC PRECONDITIONING; KALLIKREIN KININ SYSTEM; KALLIKREIN URINE LEVEL; KIDNEY BLOOD FLOW; KIDNEY COLLECTING TUBULE; KIDNEY CORTEX; KIDNEY MEDULLA; KIDNEY TUBULE ABSORPTION; KIDNEY TUBULE CELL; MEAN ARTERIAL PRESSURE; MOUSE STRAIN; NATRIURESIS; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PATHOPHYSIOLOGY; POTASSIUM CURRENT; POTASSIUM TRANSPORT; REPERFUSION; REVIEW; SALT INTAKE; SALT SENSITIVE HYPERTENSION; SODIUM ABSORPTION; SODIUM EXCRETION; SODIUM INTAKE; SPONTANEOUSLY HYPERTENSIVE RAT; SYMPATHETIC NERVE; SYSTOLIC BLOOD PRESSURE; VASCULAR SMOOTH MUSCLE; VASOCONSTRICTION; VASODILATATION;

EID: 77951929280     PISSN: None     EISSN: 14248247     Source Type: Journal    
DOI: 10.3390/ph3010059     Document Type: Review

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