In vivo transfer of antisense oligonucleotide against urinary kininase blunts deoxycorticosterone acetate-salt hypertension in rats

British Journal of Pharmacology

Volumn 131, Issue 4, 2000, Pages 820-826

  Hayashi, Izumi ^a   Majima, Masataka ^a   Fujita, Tomoe ^a   Okumura, Toshiaki ^a   Kumagai, Yuji ^a   Tomita, Naruya ^b   Morishita, Ryuichi ^b   Higaki, Jitsuo ^b   Ogiwara, Toshio ^b  

^a KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

Antisense oligodeoxyribonucleotide; Carboxypeptidase Y; DOCA salt hypertension; Kininase; Renal kallikrein kinin system

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CARBOXYPEPTIDASE C; DEOXYCORTICOSTERONE ACETATE; DIPEPTIDYL CARBOXYPEPTIDASE; EBELACTONE B; KININASE; LACTONE DERIVATIVE; LISINOPRIL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE MEASUREMENT; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; GENETIC TRANSFECTION; HYPERTENSION; KALLIKREIN KININ SYSTEM; MALE; NATRIURESIS; NONHUMAN; PRIORITY JOURNAL; RAT; SODIUM URINE LEVEL;

EID: 0035229868     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703634     Document Type: Article

References (34)

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