Biphasic Effects of Nitric Oxide Radicals on Radiation-Induced Lethality and Chromosome Aberrations in Human Lung Cancer Cells Carrying Different p53 Gene Status

International Journal of Radiation Oncology Biology Physics

Volumn 77, Issue 2, 2010, Pages 559-565

  Su, Xiaoming ^a,b   Takahashi, Akihisa ^b   Guo, Guozhen ^a   Mori, Eiichiro ^b   Okamoto, Noritomo ^b   Ohnishi, Ken ^b   Iwasaki, Toshiyasu ^c   Ohnishi, Takeo ^b  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b NARA MEDICAL UNIVERSITY   (Japan)

^c CENTRAL RESEARCH INSTITUTE OF ELECTRIC POWER INDUSTRY   (Japan)

Author keywords

Apoptosis; Chromosome aberration; NO; p53; Radiosensitivity

Indexed keywords

APOPTOSIS; BIPHASIC EFFECTS; CELL KILLING; CELL LINES; CELL SURVIVAL; CHROMOSOME ABERRATION; CONCENTRATION RANGES; CULTURE MEDIUM; DEOXYURIDINE; END-LABELING; HIGH CONCENTRATION; HOECHST; HUMAN LUNG; HUMAN LUNG CANCER CELL LINE; HUMAN LUNG CANCER CELLS; ISOSORBIDE; NO DONOR; P53 GENE; PARENTAL CELLS; RADIATION-INDUCED; RADIO-SENSITIZATION; RADIORESISTANCE; STAINING ASSAYS; TRIPHOSPHATE; WILD TYPES; X-IRRADIATION;

ABERRATIONS; BIOLOGICAL ORGANS; CELL DEATH; CHROMOSOMES; CONCENTRATION (PROCESS); IRRADIATION; NITRIC OXIDE; NUCLEIC ACIDS; RADIATION EFFECTS; RADIOTHERAPY;

CELL CULTURE;

2 (4 CARBOXYPHENYL) 4,4,5,5 TETRAMETHYLIMIDAZOLINE 1 OXYL 3 OXIDE; ISOSORBIDE DINITRATE; NITRIC OXIDE; PROTEIN P53; RADICAL;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER RESISTANCE; CELL SURVIVAL; CHROMOSOME ABERRATION; CONTROLLED STUDY; GENE CONSTRUCT; GENETIC TRANSFECTION; HETEROZYGOTE; HUMAN; HUMAN CELL; LUNG CANCER; PRIORITY JOURNAL; RADIOSENSITIVITY; RADIOSENSITIZATION; WILD TYPE;

APOPTOSIS; BENZOATES; CELL LINE, TUMOR; CELL SURVIVAL; CHROMOSOME ABERRATIONS; CHROMOSOME BANDING; GENES, P53; HUMANS; IMIDAZOLES; IN SITU NICK-END LABELING; ISOSORBIDE DINITRATE; LUNG NEOPLASMS; NITRIC OXIDE; NITRIC OXIDE DONORS; RADIATION TOLERANCE; TUMOR STEM CELL ASSAY;

EID: 77951880022     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2009.12.059     Document Type: Article

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