Hdm2 and Nitric Oxide Radicals Contribute to the P53-Dependent Radioadaptive Response

International Journal of Radiation Oncology Biology Physics

Volumn 71, Issue 2, 2008, Pages 550-558

  Takahashi, Akihisa ^a   Matsumoto, Hideki ^b   Ohnishi, Takeo ^a  

^a NARA MEDICAL UNIVERSITY   (Japan)

^b UNIVERSITY OF FUKUI   (Japan)

Author keywords

Hdm2; NO; p53; Radioadaptive response; Radiobiology

Indexed keywords

CELLS; ENZYME INHIBITION; FREE RADICALS; NITROGEN OXIDES;

RADIOADAPTIVE RESPONSE; RADIOBIOLOGY;

MATERIALS SCIENCE;

2 (4 CARBOXYPHENYL) 4,4,5,5 TETRAMETHYLIMIDAZOLINE 1 OXYL 3 OXIDE; 5,5' (2,5 FURANIDIYL)BIS 2 THIOPHENEMETHANOL; AMINOGUANIDINE; INDUCIBLE NITRIC OXIDE SYNTHASE; ISOSORBIDE DINITRATE; METHANOL DERIVATIVE; NITRIC OXIDE; NUTLIN 3; PROTEIN MDM2; PROTEIN P53;

ARTICLE; CELL SURVIVAL; CHROMOSOME ABERRATION; CONTROLLED STUDY; DICENTRIC CHROMOSOME; ENZYME ACTIVATION; GENE MUTATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; RADIATION DOSE; RADIOSENSITIVITY; SCORING SYSTEM; TREATMENT RESPONSE; WESTERN BLOTTING; WILD TYPE;

CELL LINE, TUMOR; CELL SURVIVAL; CHROMOSOME ABERRATIONS; CYCLIC N-OXIDES; FREE RADICAL SCAVENGERS; GENES, P53; GUANIDINES; HUMANS; IMIDAZOLES; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PIPERAZINES; PROTO-ONCOGENE PROTEINS C-MDM2; RADIATION TOLERANCE; TIME FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 43049165775     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2008.02.001     Document Type: Article

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