p53-independent thermosensitization by mitomycin C in human non-small-cell lung cancer cells

International Journal of Radiation Oncology Biology Physics

Volumn 59, Issue 3, 2004, Pages 852-860

  Jin, Zhao Hui ^a   Matsumoto, Hideki ^a   Hayashi, Sachiko ^a   Hatashita, Masanori ^a   Ohtsubo, Toshio ^a   Shioura, Hiroki ^a   Kitai, Ryuhei ^a   Kano, Eiichi ^a  

^a UNIVERSITY OF FUKUI   (Japan)

Author keywords

Apoptosis; Human lung cancer; Hyperthermia; Mitomycin C; p53

Indexed keywords

ASSAYS; CELLS; GENES; PATIENT TREATMENT; TUMORS;

HYPERTHERMIA; THERMOSENSITIZATION;

ONCOLOGY;

ANTINEOPLASTIC AGENT; HEAT SHOCK PROTEIN 72; MITOMYCIN C; MUTANT PROTEIN; NEOMYCIN; PROTEIN P53;

APOPTOSIS; ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL FRACTIONATION; CELL KILLING; COLONY FORMING UNIT; CONTROLLED STUDY; DRUG EFFECT; GENE MUTATION; GENETIC TRANSFECTION; HEAT SENSITIVITY; HUMAN; HUMAN CELL; HYPERTHERMIA; LUNG NON SMALL CELL CANCER; MITOSIS INHIBITION; PRIORITY JOURNAL; PROTEIN FUNCTION; WILD TYPE;

ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; CARCINOMA, NON-SMALL-CELL LUNG; CELL CYCLE; CELL LINE, TUMOR; COMBINED MODALITY THERAPY; DRUG RESISTANCE, NEOPLASM; GENES, P53; HEAT-SHOCK PROTEINS; HSP72 HEAT-SHOCK PROTEINS; HUMANS; HYPERTHERMIA, INDUCED; LUNG NEOPLASMS; MITOMYCIN; NEOMYCIN; TRANSFECTION; TUMOR STEM CELL ASSAY;

EID: 2942558527     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2004.01.033     Document Type: Article

References (42)

1. Kastan M.B., Onyekwere O., Sidransky D., et al. Participation of p53 protein in the cellular response to DNA damage. Cancer Res. 51:1991;6304-6311
2. Matsumoto H., Wang X., Ohnishi T. Binding between wild-type p53 and hsp72 accumulated after UV and γ-ray irradiation. Cancer Lett. 92:1995;127-133
3. Latonen L., Taya Y., Laiho M. UV-radiation induces dose-dependent regulation of p53 response and modulates p53-HDM2 interaction in human fibroblasts. Oncogene. 20:2001;6784-6793
4. Matsumoto H., Hayashi S., Hatashita M., et al. Nitric oxide is an initiator of intercellular signal transduction for stress response after hyperthermia in mutant p53 cells of human glioblastoma. Cancer Res. 59:1999;3239-3244
5. Blagosklonny M.V., El-Deiry W.S. Acute overexpression of wt p53 facilitates anticancer drug-induced death of cancer and normal cells. Int J Cancer. 75:1998;933-940
6. Matsumoto H., Shimura M., Omatsu T., et al. p53 proteins accumulated by heat stress associate with heat shock proteins HSP72/HSC73 in human glioblastoma cell lines. Cancer Lett. 87:1994;39-46
7. 1-phase checkpoint by low-oxygen conditions is independent of p53 status. Mol Cell Biol. 14:1994;6264-6277
8. Ohtsubo T., Wang X., Takahashi A., et al. p53-dependent induction of WAF1 by a low-pH culture condition in human glioblastoma cells. Cancer Res. 57:1997;3910-3913
9. Levine A.J. p53, the cellular gatekeeper for growth and division. Cell. 88:1997;323-331
10. Clarke A.R., Purdie C.A., Harrison D.J., et al. Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature. 362:1993;849-852
11. 2 delay. Cancer Res. 55:1995;1643-1648
12. Bristow R.G., Jang A., Peacock J., et al. Mutant p53 increases radioresistance in rat embryo fibroblasts simultaneously transfected with HPV16-E7 and/or activated H-ras. Oncogene. 9:1994;1527-1536
13. Hawkins D.S., Demers G.W., Galloway D.A. Inactivation of p53 enhances sensitivity to multiple chemotherapeutic agents. Cancer Res. 56:1996;892-898
14. Fan S., Smith M.L., Rivet D.J. 2nd, et al. Disruption of p53 function sensitizes breast cancer MCF-7 cells to cisplatin and pentoxifylline. Cancer Res. 55:1995;1649-1654
15. Biard D.S., Martin M., Rhun Y.L., et al. Concomitant p53 gene mutation and increased radiosensitivity in rat lung embryo epithelial cells during neoplastic development. Cancer Res. 54:1994;3361-3364
16. Slichenmyer W.J., Nelson W.G., Slebos R.J., et al. Loss of a p53-associated G1 checkpoint does not decrease cell survival following DNA damage. Cancer Res. 53:1993;4164-4168
17. Brachman D.G., Beckett M., Graves D., et al. p53 mutation does not correlate with radiosensitivity in 24 head and neck cancer cell lines. Cancer Res. 53:1993;3667-3669
18. Matsumoto H., Takahashi A., Wang X., et al. Transfection of p53-knockout mouse fibroblasts with wild-type p53 increases the thermosensitivity and stimulates apoptosis induced by heat stress. Int J Radiat Oncol Biol Phys. 38:1997;1089-1095
19. Ota I., Ohnishi K., Takahashi A., et al. Transfection with mutant p53 gene inhibits heat-induced apoptosis in a head and neck cell line of human squamous cell carcinoma. Int J Radiat Oncol Biol Phys. 47:2000;495-501
20. Bull J.M. An update on the anticancer effects of a combination of chemotherapy and hyperthermia. Cancer Res. 44:(Suppl.):1984;4853s-4856s
21. Issels R.D. Hyperthermia and thermochemotherapy. Cancer Treat Res. 67:1993;143-160
22. Urano M., Kuroda M., Nishimura Y. For the clinical application of thermochemotherapy given at mild temperatures. Int J Hyperthermia. 15:1999;79-107
23. Wallner K.E., Li G.C. Effect of drug exposure duration and sequencing on hyperthermic potentiation of mitomycin-C and cisplatin. Cancer Res. 47:1987;493-495
24. Ning S., Hahn G.M. Combination therapy Lonidamine, hyperthermia, and chemotherapy against the RIF-1 tumor in vivo. Cancer Res. 51:1991;5910-5914
25. Barlogie B., Corry P.M., Drewinko B. In vitro thermochemotherapy of human colon cancer cells with cis-dichlorodiammineplatinum(II) and mitomycin C. Cancer Res. 40:1980;1165-1168
26. Wallner K.E., Banda M., Li G.C. Hyperthermic enhancement of cell killing by mitomycin C in mitomycin C-resistant Chinese hamster ovary cells. Cancer Res. 47:1987;1308-1312
27. Rockwell S., Sartorelli A.C., Tomasz M., et al. Cellular pharmacology of quinone bioreductive alkylating agents. Cancer Metastasis Rev. 12:1993;165-176
28. Kano E., Furuya M., Nitta K., et al. Effects of anti-tumor drugs on thermotolerance development and thermosensitivity of thermotolerant cells. Kano E. Current research in hyperthermia oncology. 1988;109-125 Academic Press, London
29. Teicher B.A., Kowal C.D., Kennedy K.A., et al. Enhancement by hyperthermia of the in vitro cytotoxicity of mitomycin C toward hypoxic tumor cells. Cancer Res. 41:1981;1096-1099
30. Matsumoto H., Hayashi S., Jin Z.H., et al. Intercellular signaling mediated by nitric oxide in human glioblastoma cells. Methods Enzymol. 359:2002;280-286
31. Okamoto K., Shinoura N., Egawa N., et al. Adenovirus-mediated transfer of p53 augments hyperthermia-induced apoptosis in U251 glioma cells. Int J Radiat Oncol Biol Phys. 50:2001;525-531
32. Hahn G.M. Mechanisms of heat action. Hahn G.M. Hyperthermia and cancer. 1982;87-130 Plenum Press, New York
33. Harmon B.V., Corder A.M., Collins R.J., et al. Cell death induced in a murine mastocytoma by 42-47°C heating in vitro Evidence that the form of death changes from apoptosis to necrosis above a critical heat load. Int J Radiat Biol. 58:1990;845-858
34. Ohtsubo T., Igawa H., Saito T., et al. Enhancement of cell killing by induction of apoptosis after treatment with mild hyperthermia at 42°C and cisplatin. Radiat Res. 156:2001;103-109
35. Gorczyca W., Gong J., Ardelt B., et al. The cell cycle related differences in susceptibility of HL-60 cells to apoptosis induced by various antitumor agents. Cancer Res. 53:1993;3186-3192
36. Zhu W.G., Aramaki R., Cai Y., et al. Promotion of heat-induced apoptosis in FM3A cells by aprotease inhibitors. Biochem Biophys Res Commun. 225:1996;924-931
37. Debes A., Rommel F., Breise M., et al. In vitro test-system for chemo- and thermosensitivity An analysis of survival fractions and cell-cycle distributions in human Ewing's sarcomas as a model for tumors in pediatric oncology. Klin Pädiatr. 214:2002;223-229
38. 2-phase delays after irradiation and/or heat treatment as assessed by two-parameter flow cytometry. Radiat Res. 155:2001;50-56
39. Ohtsuka K., Utsumi K.R., Kaneda T., et al. Effect of ATP on the release of hsp 70 and hsp 40 from the nucleus in heat-shocked HeLa cells. Exp Cell Res. 209:1993;357-366
40. Matsumoto H., Hayashi S., Shioura H., et al. Suppression of heat-induced HSF activation by CDDP in human glioblastoma cells. Int J Radiat Oncol Biol Phys. 41:1998;915-920
41. Jin Z.H., Shioura H., Kano E., et al. Effects of combined treatment with 40°C hyperthermia and bleomycin on the accumulation of heat shock protein in murine L cells. Int J Oncol. 20:2002;137-142
42. Ohtsubo T., Kano E., Ueda K., et al. Enhancement of heat-induced heat shock protein (hsp)72 accumulation by doxorubicin (Dox) in vitro. Cancer Lett. 159:2000;49-55