Synthesis and evaluation of benzoquinolinone derivatives as SARS-CoV 3CL protease inhibitors

Bulletin of the Korean Chemical Society

Volumn 31, Issue 1, 2010, Pages 87-91

  Ahn, Tae Young ^a,b   Kuo, Chih Jung ^c,d   Liu, Hun Ge ^c   Ha, Deok Chan ^b   Liang, Po Huang ^c,d   Jung, Young Sik ^a  

^a Korea Research Institute of Chemical Technology   (South Korea)

^b Korea University   (South Korea)

^c INSTITUTE OF BIOLOGICAL CHEMISTRY   (Taiwan)

^d ACADEMIA SINICA   (Taiwan)

Author keywords

3C protease; Benzoquinoline; Computer modeling; Coronavirus; Picornavirus

Indexed keywords

ANTIVIRALS; BENZOQUINOLINE; COMPUTER MODELING; CORONAVIRUSES; H-BONDS; HYDROPHOBIC INTERACTIONS; HYDROXYL GROUPS; PICORNAVIRUS; PROTEASE INHIBITOR; SEVERE ACUTE RESPIRATORY SYNDROME;

HYDROPHOBICITY; SYNTHESIS (CHEMICAL);

COMPUTER SIMULATION;

EID: 77951863779     PISSN: 02532964     EISSN: 12295949     Source Type: Journal    
DOI: 10.5012/bkcs.2010.31.01.087     Document Type: Article

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