Loss of Matrix Metalloproteinase-13 Attenuates Murine Radiation-Induced Pulmonary Fibrosis

International Journal of Radiation Oncology Biology Physics

Volumn 77, Issue 2, 2010, Pages 582-590

  Flechsig, Paul ^a   Hartenstein, Bettina ^b   Teurich, Sybille ^b   Dadrich, Monika ^a   Hauser, Kai ^a   Abdollahi, Amir ^a   Gröne, Hermann Josef ^a   Angel, Peter ^b   Huber, Peter E ^b  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Ionizing radiation; MMP13; Pulmonary fibrosis; Volume computed tomography

Indexed keywords

C57BL/6 MICE; CLINICAL OUTCOME; COMPUTED TOMOGRAPHY; EXTRACELLULAR MATRICES; GOOD CORRELATIONS; KNOCKOUT MICE; LUNG FIBROSIS; MATRIX METALLOPROTEINASES; POTENTIAL DRUG; PULMONARY FIBROSIS; QUANTITATIVE RESULT; RADIATION-INDUCED; THORACIC IRRADIATIONS; WILD TYPES;

BLOOD VESSELS; COMPUTERIZED TOMOGRAPHY; ENZYME ACTIVITY; ENZYME INHIBITION; HISTOLOGY; IONIZING RADIATION; IRRADIATION; MAGNETIC RESONANCE IMAGING; PATHOLOGY; RADIATION SHIELDING; RADIOACTIVITY; RESONANCE;

BIOLOGICAL ORGANS;

COLLAGENASE 3;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER RADIOTHERAPY; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DISEASE RESISTANCE; HISTOPATHOLOGY; INFLAMMATION; KNOCKOUT MOUSE; LUNG FIBROSIS; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; SURVIVAL RATE; WILD TYPE;

ANIMALS; LONGEVITY; LUNG; MAGNETIC RESONANCE IMAGING; MATRIX METALLOPROTEINASE 13; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PULMONARY FIBROSIS; RADIATION PNEUMONITIS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 77951842942     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2009.12.043     Document Type: Article

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