Synthesis of C-4′Truncated Phosphonated Carbocyclic 2′-Oxa-3′-azanucleosides as Antiviral Agents

Journal of Organic Chemistry

Volumn 75, Issue 9, 2010, Pages 2798-2805

  Piperno, Anna ^a   Giofrè, Salvatore V ^a   Iannazzo, Daniela ^a   Romeo, Roberto ^a   Romeo, Giovanni ^a   Chiacchio, Ugo ^b   Rescifina, Antonio ^b   Piotrowska, Dorota G ^c  

^a UNIVERSITY OF MESSINA   (Italy)

^b UNIVERSITY OF CATANIA   (Italy)

^c MEDICAL UNIVERSITY OF LODZ   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

ANOMERS; ANTIVIRAL AGENTS; BIOLOGICAL ASSAYS; DFT CALCULATION; DIPOLAR CYCLOADDITIONS; GOOD YIELD; HIGH YIELD; NANOMOLAR RANGE; NITRONES; NUCLEOBASES; QUANTUM MECHANICAL; TENOFOVIR; TWO-STEP PROCEDURE; VINYL ACETATES;

BIOMOLECULES; CYCLOADDITION; ONCOGENIC VIRUSES; QUANTUM THEORY; SULFUR COMPOUNDS;

SYNTHESIS (CHEMICAL);

ANTIVIRUS AGENT; NITRONE; NUCLEIC ACID BASE; NUCLEOSIDE DERIVATIVE; RNA DIRECTED DNA POLYMERASE; TENOFOVIR; VINYL ACETATE; ZIDOVUDINE;

ARTICLE; BIOASSAY; CHEMICAL REACTION; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYCLOADDITION; DENSITY FUNCTIONAL THEORY; DRUG SYNTHESIS; ENZYME INHIBITION; NONHUMAN; QUANTUM MECHANICS; RETROVIRUS; THEORY;

ACIDS, CARBOCYCLIC; AZA COMPOUNDS; CELL LINE; CYCLIZATION; HUMANS; MOLECULAR STRUCTURE; NITROGEN OXIDES; NUCLEOSIDES; PHOSPHONIC ACIDS; QUANTUM THEORY; RETROVIRIDAE; REVERSE TRANSCRIPTASE INHIBITORS; VINYL COMPOUNDS;

EID: 77951832717     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo902485m     Document Type: Article

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