Enantioselective syntheses and cytotoxicity of N,O-nucleosides

Journal of Medicinal Chemistry

Volumn 46, Issue 17, 2003, Pages 3696-3702

  Chiacchio, Ugo ^a   Corsaro, Antonino ^a   Iannazzo, Daniela ^b   Piperno, Anna ^b   Pistarà, Venerando ^a   Rescifina, Antonio ^a   Romeo, Roberto ^b   Valveri, Vincenza ^b   Mastino, Antonio ^b   Romeo, Giovanni ^b  

^a UNIVERSITY OF CATANIA   (Italy)

^b UNIVERSITY OF MESSINA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

4' AZA 2',3' DIDEOXYNUCLEOSIDE DERIVATIVE; 5 FLUORO 1 ISOXAZOLIDIN 5 YL 1H PYRIMIDINE 2,4 DIONE; FAS ANTIGEN; N,O NUCLEOSIDE DERIVATIVE; NITRONE; NUCLEOSIDE DERIVATIVE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL ASSAY; CELL DEATH; CHEMICAL REACTION; CHIRALITY; CONCENTRATION RESPONSE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CYCLOADDITION; CYTOPATHOGENIC EFFECT; DRUG DESIGN; DRUG EFFICACY; DRUG MECHANISM; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; ENANTIOSELECTIVITY; ENZYME ACTIVITY; ENZYME ASSAY; HUMAN; HUMAN CELL; LYMPHOID CELL; MONOCYTE; REACTION ANALYSIS; TECHNIQUE;

ANTIGENS, CD95; ANTINEOPLASTIC AGENTS; ANTIVIRAL AGENTS; APOPTOSIS; CASPASE 3; CASPASE 8; CASPASE 9; CASPASES; CELL LINE; DIDEOXYNUCLEOSIDES; HUMANS; ISOXAZOLES; LYMPHOID TISSUE; MOLECULAR CONFORMATION; MONOCYTES; QUANTUM THEORY; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED; URIDINE;

EID: 0042231987     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0308186     Document Type: Article

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