메뉴 건너뛰기




Volumn 17, Issue 3, 2010, Pages 187-201

Glioma diagnosis: Immunohistochemistry and beyond

Author keywords

1p 19q; Diagnosis; EGFR; Glial neoplasm (glioma); MGMT; PTEN (chromosome 10)

Indexed keywords

EPIDERMAL GROWTH FACTOR; ERLOTINIB; GEFITINIB; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; TEMOZOLOMIDE;

EID: 77951758886     PISSN: 10724109     EISSN: 15334031     Source Type: Journal    
DOI: 10.1097/PAP.0b013e3181d98cd9     Document Type: Review
Times cited : (47)

References (96)
  • 1
    • 77951719305 scopus 로고    scopus 로고
    • Central Brain Tumor Registry of the United States, 2009-2010
    • CBTRUS [http://www.cbtrus.org/reports/reports.html]. Central Brain Tumor Registry of the United States, 2009-2010.
  • 3
    • 50449092000 scopus 로고    scopus 로고
    • Diagnosis of glioma: Role of neuropathology
    • Brat DJ, Prayson RA, Ryken TC, et al. Diagnosis of glioma: role of neuropathology. J Neurooncol. 2008;89:287-311.
    • (2008) J Neurooncol , vol.89 , pp. 287-311
    • Brat, D.J.1    Prayson, R.A.2    Ryken, T.C.3
  • 5
    • 34250877865 scopus 로고    scopus 로고
    • Genetic pathways to primary and secondary glioblastoma
    • Ohgaki H, Kleihues P. Genetic pathways to primary and secondary glioblastoma. Am J Pathol 2007;170:1445-1453.
    • (2007) Am J Pathol , vol.170 , pp. 1445-1453
    • Ohgaki, H.1    Kleihues, P.2
  • 6
    • 48249125791 scopus 로고    scopus 로고
    • Malignant gliomas in adults
    • Wen PY, Kesari S. Malignant gliomas in adults. N Engl JMed. 2008;359:492-507.
    • (2008) N Engl JMed , vol.359 , pp. 492-507
    • Wen, P.Y.1    Kesari, S.2
  • 7
    • 33748533494 scopus 로고    scopus 로고
    • Correlation among pathology, genotype, and patient outcomes in glioblastoma
    • Homma T, Fukushima T, Vaccarella S, et al. Correlation among pathology, genotype, and patient outcomes in glioblastoma. J Neuropathol Exp Neurol. 2006;9:846-854.
    • (2006) J Neuropathol Exp Neurol , vol.9 , pp. 846-854
    • Homma, T.1    Fukushima, T.2    Vaccarella, S.3
  • 8
    • 73249150097 scopus 로고    scopus 로고
    • Giant cell glioblastoma: A glioblastoma subtype with distinct epidemiology and superior prognosis
    • Kozak KR, Moody JS. Giant cell glioblastoma: a glioblastoma subtype with distinct epidemiology and superior prognosis. Neurooncol. 2009;11:833-841.
    • (2009) Neurooncol , vol.11 , pp. 833-841
    • Kozak, K.R.1    Moody, J.S.2
  • 9
    • 0027602690 scopus 로고
    • Keratin intermediate filament expression in astrocytic neoplasms: Analysis by immunocytochemistry, western blot, and northern hybridization
    • Cosgrove MM, Rich KA, Kunin SA, et al. (1993) Keratin intermediate filament expression in astrocytic neoplasms: analysis by immunocytochemistry, western blot, and northern hybridization. Mod Pathol. 1993;6:342-347.
    • (1993) Mod Pathol , vol.6 , pp. 342-347
    • Cosgrove, M.M.1    Rich, K.A.2    Kunin, S.A.3
  • 10
    • 0032862110 scopus 로고    scopus 로고
    • Evaluation of epithelial and keratin markers in glioblastoma multiforme: An immunohistochemical study
    • Oh D, Prayson RA. Evaluation of epithelial and keratin markers in glioblastoma multiforme: an immunohistochemical study. Arch Pathol Lab Med. 1999;123:917-920.
    • (1999) Arch Pathol Lab Med , vol.123 , pp. 917-920
    • Oh, D.1    Prayson, R.A.2
  • 11
    • 0030729006 scopus 로고    scopus 로고
    • P53 mutations versus EGF receptor expression in giant cell glioblastomas
    • Peraud A, Watanabe K, Plate KH, et al. p53 mutations versus EGF receptor expression in giant cell glioblastomas. J Neuropathol Exp Neurol. 1997;56:1236-1241.
    • (1997) J Neuropathol Exp Neurol , vol.56 , pp. 1236-1241
    • Peraud, A.1    Watanabe, K.2    Plate, K.H.3
  • 12
    • 0030921607 scopus 로고    scopus 로고
    • Molecular genetic analysis of giant cell glioblastomas
    • Meyer-Puttlitz B, Hayashi Y, Waha A, et al. Molecular genetic analysis of giant cell glioblastomas. Am J Pathol. 1997;151: 853-857.
    • (1997) Am J Pathol , vol.151 , pp. 853-857
    • Meyer-Puttlitz, B.1    Hayashi, Y.2    Waha, A.3
  • 13
    • 0032988046 scopus 로고    scopus 로고
    • Genetic profile of the giant cell glioblastoma
    • Peraud A, Wantanabe K, Schwechheimer K, et al. Genetic profile of the giant cell glioblastoma. Lab Invest. 1999;79: 123-129.
    • (1999) Lab Invest , vol.79 , pp. 123-129
    • Peraud, A.1    Wantanabe, K.2    Schwechheimer, K.3
  • 14
    • 0034764277 scopus 로고    scopus 로고
    • Small cell architecture-a histological equivalent of EGFR amplification in glioblastoma multiforme?
    • Burger PC, Pearl DK, Aldape K, et al. Small cell architecture-a histological equivalent of EGFR amplification in glioblastoma multiforme? J Neuropathol Exp Neurol. 2001;60: 1099-1104.
    • (2001) J Neuropathol Exp Neurol , vol.60 , pp. 1099-1104
    • Burger, P.C.1    Pearl, D.K.2    Aldape, K.3
  • 15
    • 7644241538 scopus 로고    scopus 로고
    • Small cell astrocytoma: An aggressive variant that is clinicopathologically and genetically distinct from anaplastic oligodendroglioma
    • Perry A, Aldape KD, George DH, et al. Small cell astrocytoma: an aggressive variant that is clinicopathologically and genetically distinct from anaplastic oligodendroglioma. Cancer. 2004;101:2318-2326.
    • (2004) Cancer , vol.101 , pp. 2318-2326
    • Perry, A.1    Aldape, K.D.2    George, D.H.3
  • 16
    • 52949127312 scopus 로고    scopus 로고
    • An integrated genomic analysis of human glioblastoma multiforme
    • Parsons DW, Jones S, Zhang X, et al. An integrated genomic analysis of human glioblastoma multiforme. Science. 2008;321: 1807-1812.
    • (2008) Science , vol.321 , pp. 1807-1812
    • Parsons, D.W.1    Jones, S.2    Zhang, X.3
  • 17
    • 60849115270 scopus 로고    scopus 로고
    • IDH1 and IDH2 mutations in gliomas
    • Yan H, Parsons DW, Jin G, et al. IDH1 and IDH2 mutations in gliomas. N Engl J Med. 2009;360:765-773.
    • (2009) N Engl J Med , vol.360 , pp. 765-773
    • Yan, H.1    Parsons, D.W.2    Jin, G.3
  • 18
    • 56749156414 scopus 로고    scopus 로고
    • Analysis of the IDH1 codon 132 mutation in brain tumors
    • Balss J, Meyer J, Mueller W, et al. Analysis of the IDH1 codon 132 mutation in brain tumors. Acta Neuropathol. 2008;116: 597-602.
    • (2008) Acta Neuropathol , vol.116 , pp. 597-602
    • Balss, J.1    Meyer, J.2    Mueller, W.3
  • 19
    • 65349150503 scopus 로고    scopus 로고
    • IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas
    • Wantanabe T, Nobusawa S, Kleihues P, et al. IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas. Am J Pathol. 2009;174:1149-1153.
    • (2009) Am J Pathol , vol.174 , pp. 1149-1153
    • Wantanabe, T.1    Nobusawa, S.2    Kleihues, P.3
  • 20
    • 71549122009 scopus 로고    scopus 로고
    • Characterization of R132H mutation-specific IDH1 antibody binding in brain tumors
    • Capper D,Weibert S, Balss J, et al. Characterization of R132H mutation-specific IDH1 antibody binding in brain tumors. Brain Pathol. 2010;20:245-254.
    • (2010) Brain Pathol , vol.20 , pp. 245-254
    • Capper Dweibert, S.1    Balss, J.2
  • 21
    • 70449708940 scopus 로고    scopus 로고
    • A monoclonal antibody IMab-1 specifically recognizes IDH1R132H, the most common glioma-derived mutation
    • Kato Y, Jin G, Kuan C-T, et al. A monoclonal antibody IMab-1 specifically recognizes IDH1R132H, the most common glioma-derived mutation. Biochem Biophys Res Com. 2009;390: 547-551.
    • (2009) Biochem Biophys Res Com , vol.390 , pp. 547-551
    • Kato, Y.1    Jin, G.2    Kuan, C.-T.3
  • 22
    • 70249097408 scopus 로고    scopus 로고
    • Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas
    • Sanson M, Marie Y, Paris S, et al. Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas. J Clin Oncol. 2009;27:4150-4154.
    • (2009) J Clin Oncol , vol.27 , pp. 4150-4154
    • Sanson, M.1    Marie, Y.2    Paris, S.3
  • 23
    • 73349109131 scopus 로고    scopus 로고
    • Diagnostic use of IDH1/2 mutation analysis in routine clinical testing of formalin-fixed, paraffin-embedded glioma tissues
    • Horbinski C, Kofler J, Kelly LM, et al. Diagnostic use of IDH1/2 mutation analysis in routine clinical testing of formalin-fixed, paraffin-embedded glioma tissues. J Neuropathol Exp Neurol. 2009;68:1319-1325.
    • (2009) J Neuropathol Exp Neurol , vol.68 , pp. 1319-1325
    • Horbinski, C.1    Kofler, J.2    Kelly, L.M.3
  • 24
    • 52649172327 scopus 로고    scopus 로고
    • Frequent gains at chromosome 7q34 involving BRAF in pilocytic astrocytoma
    • Bar EE, Lin A, Tihan T, et al. Frequent gains at chromosome 7q34 involving BRAF in pilocytic astrocytoma. J Neuropathol Exp Neurol. 2008;67:878-887.
    • (2008) J Neuropathol Exp Neurol , vol.67 , pp. 878-887
    • Bar, E.E.1    Lin, A.2    Tihan, T.3
  • 25
    • 55349107544 scopus 로고    scopus 로고
    • Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas
    • Jones DTW, Kocialkowski S, Liu L, et al. Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas. Cancer Res. 2008;68: 8673-8677.
    • (2008) Cancer Res , vol.68 , pp. 8673-8677
    • Jones, D.T.W.1    Kocialkowski, S.2    Liu, L.3
  • 26
    • 0036020497 scopus 로고    scopus 로고
    • Immunohistochemical markers for prognosis of cerebral glioblastomas
    • DOI 10.1023/A:1016218117251
    • Korshunov A, Golanov A, Sycheva R. Immunohistochemical markers for prognosis of cerebral glioblastomas. J Neurooncol. 2002;58:217-236. (Pubitemid 34830634)
    • (2002) Journal of Neuro-Oncology , vol.58 , Issue.3 , pp. 217-236
    • Korshunov, A.1    Golanov, A.2    Sycheva, R.3
  • 27
    • 70350741355 scopus 로고    scopus 로고
    • Prognostic significance of molecular markers and extent of resection in primary glioblastoma patients
    • Felsberg J, Rapp M, Loeser S, et al. Prognostic significance of molecular markers and extent of resection in primary glioblastoma patients. Clin Cancer Res. 2009;15:6683-6693.
    • (2009) Clin Cancer Res , vol.15 , pp. 6683-6693
    • Felsberg, J.1    Rapp, M.2    Loeser, S.3
  • 28
    • 37549070721 scopus 로고    scopus 로고
    • Expression of cell cycle inhibitors p21, p27, p14 and p16 in gliomas. Correlation with classic prognostic factors and patients' outcome
    • Zolota V, Tsamandas AC, Aroukatos P, et al. Expression of cell cycle inhibitors p21, p27, p14 and p16 in gliomas. Correlation with classic prognostic factors and patients' outcome. Neuropathology. 2008;28:35-42.
    • (2008) Neuropathology , vol.28 , pp. 35-42
    • Zolota, V.1    Tsamandas, A.C.2    Aroukatos, P.3
  • 29
    • 34249091595 scopus 로고    scopus 로고
    • Wilms tumor 1 expression in malignant gliomas and correlation of +KTS isoforms with p53 status
    • Clark AJ, Dos Santos WG, McCready J, et al. Wilms tumor 1 expression in malignant gliomas and correlation of +KTS isoforms with p53 status. J Neurosurg. 2007;107: 586-592.
    • (2007) J Neurosurg , vol.107 , pp. 586-592
    • Clark, A.J.1    Dos Santos, W.G.2    McCready, J.3
  • 30
    • 44649105059 scopus 로고    scopus 로고
    • WT1 expression distinguishes astrocytic tumor cells from normal and reactive astrocytes
    • Schittenhelm J, Mittelbronn M, Nguyen TD, et al. WT1 expression distinguishes astrocytic tumor cells from normal and reactive astrocytes. Brain Pathol. 2008;18:344-353.
    • (2008) Brain Pathol , vol.18 , pp. 344-353
    • Schittenhelm, J.1    Mittelbronn, M.2    Nguyen, T.D.3
  • 31
    • 77951762778 scopus 로고    scopus 로고
    • WT1 does not reliably distinguish reactive from neoplastic astrocytes
    • Bourne TD, Elias WJ, Mandell JW, et al. WT1 does not reliably distinguish reactive from neoplastic astrocytes. J Neuropathol Exp Neurol. 2009;69:582.
    • (2009) J Neuropathol Exp Neurol , vol.69 , pp. 582
    • Bourne, T.D.1    Elias, W.J.2    Mandell, J.W.3
  • 32
    • 13344288692 scopus 로고
    • Detection of abnormal p53 protein in progressive multifocalleukoencephalopathy
    • Bruner JM, Hair LS. Detection of abnormal p53 protein in progressive multifocalleukoencephalopathy. J Neuropathol Exp Neurol. 1993;52:271.
    • (1993) J Neuropathol Exp Neurol , vol.52 , pp. 271
    • Bruner, J.M.1    Hair, L.S.2
  • 33
    • 84901955823 scopus 로고
    • An immunohistochemical study of p53 and proliferating cell nuclear antigen expression in progressive multifocal leukoencephalopathy
    • Lammie GA, Beckett A, Courtney R, et al. An immunohistochemical study of p53 and proliferating cell nuclear antigen expression in progressive multifocal leukoencephalopathy. Acta Neuropathol. 1994;88:465-471.
    • (1994) Acta Neuropathol , vol.88 , pp. 465-471
    • Lammie, G.A.1    Beckett, A.2    Courtney, R.3
  • 34
    • 0027943003 scopus 로고
    • P53 and proliferating cell nuclear antigen expression in JC virus-infected cells of progressive multifocal leukoencephalopathy
    • Ariza A, Mate JL, Fernandez-Vasalo A, et al. P53 and proliferating cell nuclear antigen expression in JC virus-infected cells of progressive multifocal leukoencephalopathy. Hum Pathol. 1994;25:1341-1345.
    • (1994) Hum Pathol , vol.25 , pp. 1341-1345
    • Ariza, A.1    Mate, J.L.2    Fernandez-Vasalo, A.3
  • 36
    • 0032522971 scopus 로고    scopus 로고
    • Mitosis identification in diffuse gliomas: Implications for tumor grading
    • Coons SW, Pearl DK. Mitosis identification in diffuse gliomas: implications for tumor grading. Cancer. 1998;82: 1550-1555.
    • (1998) Cancer , vol.82 , pp. 1550-1555
    • Coons, S.W.1    Pearl, D.K.2
  • 37
    • 23944503109 scopus 로고    scopus 로고
    • Techniques to assess the proliferative potential of brain tumors
    • Quinones-Hinojosa A, Sanai N, Smith JS, et al. Techniques to assess the proliferative potential of brain tumors. J Neurooncol. 2005;74:19-30.
    • (2005) J Neurooncol , vol.74 , pp. 19-30
    • Quinones-Hinojosa, A.1    Sanai, N.2    Smith, J.S.3
  • 38
    • 33750846321 scopus 로고    scopus 로고
    • The clinical value of Ki-67/MIB-1 labeling in human astrocytomas
    • Johannesen AL, Torp SH. The clinical value of Ki-67/MIB-1 labeling in human astrocytomas. Pathol Oncol Res. 2006;12: 143-147.
    • (2006) Pathol Oncol Res , vol.12 , pp. 143-147
    • Johannesen, A.L.1    Torp, S.H.2
  • 39
    • 0030756094 scopus 로고    scopus 로고
    • Use of MIB-1 (Ki-67) immunoreactivity in differentiating grade II and grade III gliomas
    • Hsu DW, Louis DN, Efird JT, et al. Use of MIB-1 (Ki-67) immunoreactivity in differentiating grade II and grade III gliomas. J Neuropathol Exp Neurol. 1997;56:857-865.
    • (1997) J Neuropathol Exp Neurol , vol.56 , pp. 857-865
    • Hsu, D.W.1    Louis, D.N.2    Efird, J.T.3
  • 40
    • 0027367487 scopus 로고
    • Regional heterogeneity in the proliferative activity of human gliomas as measured by the Ki-67 labeling index
    • Coons SW, Johnson PC. Regional heterogeneity in the proliferative activity of human gliomas as measured by the Ki-67 labeling index. J Neuropathol Exp Neurol. 1993;52: 609-618.
    • (1993) J Neuropathol Exp Neurol , vol.52 , pp. 609-618
    • Coons, S.W.1    Johnson, P.C.2
  • 41
    • 0030949269 scopus 로고    scopus 로고
    • An comparison of the predictive power for survival in gliomas provided by MIB-1, bromodeoxyuridine and proliferating cell nuclear antigen with histopathologic and clinical parameters
    • McKeever PE, Ross DA, Strawderman MS, et al. An comparison of the predictive power for survival in gliomas provided by MIB-1, bromodeoxyuridine and proliferating cell nuclear antigen with histopathologic and clinical parameters. J Neuropathol Exp Neurol. 1997;56:798-805.
    • (1997) J Neuropathol Exp Neurol , vol.56 , pp. 798-805
    • McKeever, P.E.1    Ross, D.A.2    Strawderman, M.S.3
  • 42
    • 31144449690 scopus 로고    scopus 로고
    • Role of MIB1 in predicting survival in patients with glioblastomas
    • Moskowitz SI, Jin T, Prayson RA. Role of MIB1 in predicting survival in patients with glioblastomas. J Neurooncol. 2006;76: 193-200.
    • (2006) J Neurooncol , vol.76 , pp. 193-200
    • Moskowitz, S.I.1    Jin, T.2    Prayson, R.A.3
  • 43
    • 0035889909 scopus 로고    scopus 로고
    • Interobserver variability associated with the MIB-1 labeling index: High levels suggest limited prognostic usefulness for patients with primary brain tumors
    • Marie D, Liu Y, Moore SA, et al. Interobserver variability associated with the MIB-1 labeling index: high levels suggest limited prognostic usefulness for patients with primary brain tumors. Cancer. 2001;92:2720-2726.
    • (2001) Cancer , vol.92 , pp. 2720-2726
    • Marie, D.1    Liu, Y.2    Moore, S.A.3
  • 44
    • 33745035049 scopus 로고    scopus 로고
    • Assessment and prognostic significance of mitotic marker phopho-histone H3 in low and intermediate-grade infiltrating astrocytomas
    • Colman H, Giannini C, Huang L, et al. Assessment and prognostic significance of mitotic marker phopho-histone H3 in low and intermediate-grade infiltrating astrocytomas. Am J Surg Pathol. 2006;30:657-664.
    • (2006) Am J Surg Pathol , vol.30 , pp. 657-664
    • Colman, H.1    Giannini, C.2    Huang, L.3
  • 45
    • 41649101243 scopus 로고    scopus 로고
    • Central nervous system tumors with ependymal features: A broadened spectrum of primarily ependymal differentiation?
    • Lehman NL. Central nervous system tumors with ependymal features: a broadened spectrum of primarily ependymal differentiation? J Neuropathol Exp Neurol. 2008;67:177-188.
    • (2008) J Neuropathol Exp Neurol , vol.67 , pp. 177-188
    • Lehman, N.L.1
  • 46
    • 0030924429 scopus 로고    scopus 로고
    • Clear cell ependymoma: A mimic of oligodendroglioma: Clinicaopathological and ultrastructural considerations
    • Min KW, Scheithauer BW. Clear cell ependymoma: a mimic of oligodendroglioma: clinicaopathological and ultrastructural considerations. Am J Surg Pathol. 1997;21:820-826.
    • (1997) Am J Surg Pathol , vol.21 , pp. 820-826
    • Min, K.W.1    Scheithauer, B.W.2
  • 47
    • 44849113930 scopus 로고    scopus 로고
    • Clear cell ependymoma: A mimicker of oligodendroglioma-report of three cases
    • Jain D, Sharma MC, Arora R, et al. Clear cell ependymoma: a mimicker of oligodendroglioma-report of three cases. Neuropathology. 2008;28:366-371.
    • (2008) Neuropathology , vol.28 , pp. 366-371
    • Jain, D.1    Sharma, M.C.2    Arora, R.3
  • 48
    • 42649088067 scopus 로고    scopus 로고
    • Ependymal tumors with sarcomatous change ("ependymosarcoma"): A clinicaopathologic and molecular cytogenetic study
    • Rodriguez FJ, Scheithauer BW, Perry A, et al. Ependymal tumors with sarcomatous change ("ependymosarcoma"): a clinicaopathologic and molecular cytogenetic study. Am J Surg Pathol. 2008;32:699-709.
    • (2008) Am J Surg Pathol , vol.32 , pp. 699-709
    • Rodriguez, F.J.1    Scheithauer, B.W.2    Perry, A.3
  • 49
    • 33947389567 scopus 로고    scopus 로고
    • Ependymomas with neuronal differentiation: A morphologic and immunohistochemical spectrum
    • Rodriguez FJ, Scheithauer BW, Robbins PD, et al. Ependymomas with neuronal differentiation: a morphologic and immunohistochemical spectrum. Acta Neuropathol. 2007;113: 313-324.
    • (2007) Acta Neuropathol , vol.113 , pp. 313-324
    • Rodriguez, F.J.1    Scheithauer, B.W.2    Robbins, P.D.3
  • 50
    • 0024365524 scopus 로고
    • Astroblastomas: A pathological study of 23 tumors, with post-operative follow-up in 13 patients
    • Bonnin JM, Rubinstein LJ. Astroblastomas: a pathological study of 23 tumors, with post-operative follow-up in 13 patients. Neurosurgery. 1989;25:6-13.
    • (1989) Neurosurgery , vol.25 , pp. 6-13
    • Bonnin, J.M.1    Rubinstein, L.J.2
  • 51
    • 0033920234 scopus 로고    scopus 로고
    • Astroblastoma: Clinicopathologic features and chromosomal abnormalities defined by comparative genomic hybridization
    • Brat DJ, Hirose Y, Cohen KJ, et al. Astroblastoma: clinicopathologic features and chromosomal abnormalities defined by comparative genomic hybridization. Brain Pathol. 2000;10: 342-352.
    • (2000) Brain Pathol , vol.10 , pp. 342-352
    • Brat, D.J.1    Hirose, Y.2    Cohen, K.J.3
  • 52
    • 34249775516 scopus 로고    scopus 로고
    • Astroblastoma. Case report, review of the literature, and analysis of treatment strategies
    • Mangano FT, Bradford AC, Mittler MA, et al. Astroblastoma. Case report, review of the literature, and analysis of treatment strategies. J Neurosurg Sci. 2007;51:21-27.
    • (2007) J Neurosurg Sci , vol.51 , pp. 21-27
    • Mangano, F.T.1    Bradford, A.C.2    Mittler, M.A.3
  • 53
    • 26444620153 scopus 로고    scopus 로고
    • Monomorphous angiocentric glioma: A distinctive epileptogenic neoplasm with features of infiltrating astrocytoma and ependymoma
    • Wang M, Tihan T, Rojiani AM, et al. Monomorphous angiocentric glioma: A distinctive epileptogenic neoplasm with features of infiltrating astrocytoma and ependymoma. J Neuropathol Exp Neurol. 2005;64:875-881.
    • (2005) J Neuropathol Exp Neurol , vol.64 , pp. 875-881
    • Wang, M.1    Tihan, T.2    Rojiani, A.M.3
  • 54
    • 27944441266 scopus 로고    scopus 로고
    • Angiocentric neuroepithelial tumor (ANET): A new epilepsyrelated clinicopathological entity with distinctive MRI
    • Lellouch-Tubiana A, Boddaert N, Bourgeois M, et al. Angiocentric neuroepithelial tumor (ANET): a new epilepsyrelated clinicopathological entity with distinctive MRI. Brain Pathol. 2005;15:281-286.
    • (2005) Brain Pathol , vol.15 , pp. 281-286
    • Lellouch-Tubiana, A.1    Boddaert, N.2    Bourgeois, M.3
  • 55
    • 34547130731 scopus 로고    scopus 로고
    • Angiocentric glioma: Report of clinico-pathologic and genetic findings in 8 cases
    • Preusser M, Hoischen A, Novak K, et al. Angiocentric glioma: Report of clinico-pathologic and genetic findings in 8 cases. Am J Surg Pathol. 2007;31:1709-1718.
    • (2007) Am J Surg Pathol , vol.31 , pp. 1709-1718
    • Preusser, M.1    Hoischen, A.2    Novak, K.3
  • 56
    • 0031891253 scopus 로고    scopus 로고
    • Third ventricular chordoid glioma: A distinct clinicopathologic entity
    • Brat DJ, Scheithauer BW, Staugaitis SM, et al. Third ventricular chordoid glioma: a distinct clinicopathologic entity. J Neuropathol Exp Neurol. 1998;57:283-290.
    • (1998) J Neuropathol Exp Neurol , vol.57 , pp. 283-290
    • Brat, D.J.1    Scheithauer, B.W.2    Staugaitis, S.M.3
  • 57
    • 33645798309 scopus 로고    scopus 로고
    • Origin of chordoid glioma of the third ventricle
    • Leeds NE, Lang FF, Ribalta T, et al. Origin of chordoid glioma of the third ventricle. Arch Pathol Lab Med. 2006;130: 460-464.
    • (2006) Arch Pathol Lab Med , vol.130 , pp. 460-464
    • Leeds, N.E.1    Lang, F.F.2    Ribalta, T.3
  • 58
    • 66949162590 scopus 로고    scopus 로고
    • Chordoid glioma: A case report and molecular characterization of five cases
    • Horbinski C, Dacic S, McLendon RE. Chordoid glioma: a case report and molecular characterization of five cases. Brain Pathol. 2009;19:439-448.
    • (2009) Brain Pathol , vol.19 , pp. 439-448
    • Horbinski, C.1    Dacic, S.2    McLendon, R.E.3
  • 59
    • 37649000645 scopus 로고    scopus 로고
    • Molecular diagnostic testing in malignant gliomas: A practical update on predictive markers
    • Yip S, Iafrate JA, Louis DN. Molecular diagnostic testing in malignant gliomas: a practical update on predictive markers. J Neuropathol Exp Neurol. 2008;67:1-15.
    • (2008) J Neuropathol Exp Neurol , vol.67 , pp. 1-15
    • Yip, S.1    Iafrate, J.A.2    Louis, D.N.3
  • 60
    • 47549101044 scopus 로고    scopus 로고
    • Molecular predictors in glioblastoma. Toward personalized therapy
    • Colman H, Aldape K. Molecular predictors in glioblastoma. Toward personalized therapy. Arch Neurol. 2008;65:877-883.
    • (2008) Arch Neurol , vol.65 , pp. 877-883
    • Colman, H.1    Aldape, K.2
  • 61
    • 70350449411 scopus 로고    scopus 로고
    • Advances in genetics of glioblastoma: Are we reaching a critical mass?
    • Purow B, Schiff D. Advances in genetics of glioblastoma: are we reaching a critical mass? Nature Rev Neurol. 2009;5: 419-426.
    • (2009) Nature Rev Neurol , vol.5 , pp. 419-426
    • Purow, B.1    Schiff, D.2
  • 62
    • 33846981845 scopus 로고    scopus 로고
    • Clinicopathologic aspects of 1p/19q loss and the diagnosis of oligodendroglioma
    • Aldape K, Burger PC, Perry A. Clinicopathologic aspects of 1p/19q loss and the diagnosis of oligodendroglioma. Arch Pathol Lab Med. 2007;131:242-251.
    • (2007) Arch Pathol Lab Med , vol.131 , pp. 242-251
    • Aldape, K.1    Burger, P.C.2    Perry, A.3
  • 63
    • 25144459392 scopus 로고    scopus 로고
    • The prognostic impact of histology and 1p/19q status in anaplastic oligodendroglial tumors
    • McDonald JM, See SJ, Tremont IW, et al. The prognostic impact of histology and 1p/19q status in anaplastic oligodendroglial tumors. Cancer. 2005;104:1468-1477.
    • (2005) Cancer , vol.104 , pp. 1468-1477
    • McDonald, J.M.1    See, S.J.2    Tremont, I.W.3
  • 64
    • 0038172954 scopus 로고    scopus 로고
    • Ancillary FISH analysis for 1p and 19q status: Preliminary observations in 287 gliomas and oligodendroglioma mimics
    • Perry A, Fuller CE, Banerjee R, et al. Ancillary FISH analysis for 1p and 19q status: preliminary observations in 287 gliomas and oligodendroglioma mimics. Front Biosci. 2003;8: a1-a9.
    • (2003) Front Biosci , vol.8
    • Perry, A.1    Fuller, C.E.2    Banerjee, R.3
  • 65
    • 0032494479 scopus 로고    scopus 로고
    • Specific genetic predictors of chemotherapeutic response and survival in patients with anaplastic oligodendrogliomas
    • Cairncross JG, Ueki K, Zlatescu MC, et al. Specific genetic predictors of chemotherapeutic response and survival in patients with anaplastic oligodendrogliomas. J Natl Cancer Inst. 1998;90:1473-1479.
    • (1998) J Natl Cancer Inst , vol.90 , pp. 1473-1479
    • Cairncross, J.G.1    Ueki, K.2    Zlatescu, M.C.3
  • 66
    • 33745575716 scopus 로고    scopus 로고
    • Phase III trial of chemotherapy plus radiotherapy compared with radiotherapy alone for pure and mixed anaplastic oligodendroglioma: Intergroup Radiation Therapy Oncology Group Trial 9402
    • Cairncross G, Berkey B, Shaw E. Phase III trial of chemotherapy plus radiotherapy compared with radiotherapy alone for pure and mixed anaplastic oligodendroglioma: Intergroup Radiation Therapy Oncology Group Trial 9402. J Clin Oncol. 2006;24:2707-2714.
    • (2006) J Clin Oncol , vol.24 , pp. 2707-2714
    • Cairncross, G.1    Berkey, B.2    Shaw, E.3
  • 67
    • 67349223524 scopus 로고    scopus 로고
    • Predictive factors for overall and progression-free survival, and dissemination in oligodendroglial tumors
    • Kanamori M, Kumabe T, Sonoda Y, et al. Predictive factors for overall and progression-free survival, and dissemination in oligodendroglial tumors. J Neurooncol. 2009;93:219-228.
    • (2009) J Neurooncol , vol.93 , pp. 219-228
    • Kanamori, M.1    Kumabe, T.2    Sonoda, Y.3
  • 68
    • 44649088238 scopus 로고    scopus 로고
    • Anaplastic oligodendroglial tumors: Refining the correlation among histopathology, 1p 19q deletion and clinical outcome in Intergroup Radiation Therapy Oncology Group Trial 9402
    • Gianinni C, Burger PC, Berkey BA, et al. Anaplastic oligodendroglial tumors: refining the correlation among histopathology, 1p 19q deletion and clinical outcome in Intergroup Radiation Therapy Oncology Group Trial 9402. Brain Pathol. 2008;18:360-369.
    • (2008) Brain Pathol , vol.18 , pp. 360-369
    • Gianinni, C.1    Burger, P.C.2    Berkey, B.A.3
  • 69
    • 33749471311 scopus 로고    scopus 로고
    • Identification of der(1;19)(q10;p10) in five oligodendrogliomas suggests mechanism of concurrent 1p and 19q Loss
    • Griffin CA, Burger P, Morsberger BA, et al. Identification of der(1;19)(q10;p10) in five oligodendrogliomas suggests mechanism of concurrent 1p and 19q Loss. J Neuropathol Exp Neurol. 2006;65:988-994.
    • (2006) J Neuropathol Exp Neurol , vol.65 , pp. 988-994
    • Griffin, C.A.1    Burger, P.2    Morsberger, B.A.3
  • 70
    • 33750563258 scopus 로고    scopus 로고
    • A t(1;19)(q10;p10) mediates the combined deletions of 1p and 19q and predicts a better prognosis of patients with oligodendroglioma
    • Jenkins RB, Blair H, Ballman KV, et al. A t(1;19)(q10;p10) mediates the combined deletions of 1p and 19q and predicts a better prognosis of patients with oligodendroglioma. Cancer Res. 2006;66:9852-9861.
    • (2006) Cancer Res , vol.66 , pp. 9852-9861
    • Jenkins, R.B.1    Blair, H.2    Ballman, K.V.3
  • 71
    • 18344389016 scopus 로고    scopus 로고
    • Losses of chromosomes 1p and 19q are rare in pediatric oligodendrogliomas
    • Kreiger PA, Okada Y, Simon S, et al. Losses of chromosomes 1p and 19q are rare in pediatric oligodendrogliomas. Acta Neuropathol. 2005;109:387-392.
    • (2005) Acta Neuropathol , vol.109 , pp. 387-392
    • Kreiger, P.A.1    Okada, Y.2    Simon, S.3
  • 72
    • 0037884872 scopus 로고    scopus 로고
    • Pediatric oligodendrogliomas: A study of molecular alterations on 1p and 19q using fluorescence in situ hybridization
    • Raghavan R, Balani J, Perry A, et al. Pediatric oligodendrogliomas: a study of molecular alterations on 1p and 19q using fluorescence in situ hybridization. J Neuropathol Exp Neurol. 2003;62:530-537.
    • (2003) J Neuropathol Exp Neurol , vol.62 , pp. 530-537
    • Raghavan, R.1    Balani, J.2    Perry, A.3
  • 73
    • 3242722352 scopus 로고    scopus 로고
    • Population-based study on incidence, survival rates, and genetic alterations of low-grade diffuse astrocytomas and oligodendrogliomas
    • Okamoto Y, DiPatre PL, Burkhard C, et al. Population-based study on incidence, survival rates, and genetic alterations of low-grade diffuse astrocytomas and oligodendrogliomas. Acta Neuropathol. 2004;108:49-56.
    • (2004) Acta Neuropathol , vol.108 , pp. 49-56
    • Okamoto, Y.1    Dipatre, P.L.2    Burkhard, C.3
  • 74
    • 20044372154 scopus 로고    scopus 로고
    • MGMT gene silencing and benefit from temozolomide in glioblastoma
    • Hegi ME, Diserens AC, Gorlia T, et al. MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl JMed. 2005;352:997-1003.
    • (2005) N Engl JMed , vol.352 , pp. 997-1003
    • Hegi, M.E.1    Diserens, A.C.2    Gorlia, T.3
  • 75
    • 51649117107 scopus 로고    scopus 로고
    • Correlation of O6-methylguanine methyltransferase (MGMT) promoter methylation with clinical outcomes in glioblastoma and clinical strategies to modulate MGMT activity
    • Hegi ME, Liu L, Herman JG, et al. Correlation of O6-methylguanine methyltransferase (MGMT) promoter methylation with clinical outcomes in glioblastoma and clinical strategies to modulate MGMT activity. J Clin Oncol. 2008;26: 4189-4199.
    • (2008) J Clin Oncol , vol.26 , pp. 4189-4199
    • Hegi, M.E.1    Liu, L.2    Herman, J.G.3
  • 76
    • 62449258056 scopus 로고    scopus 로고
    • Recurrence pattern after temozolomide concomitant with and adjuvant to radiotherapy in newly diagnosed patients with glioblastoma: Correlation with MGMT promoter methylation status
    • Brandes AA, Tosoni A, Franceschi E, et al., Recurrence pattern after temozolomide concomitant with and adjuvant to radiotherapy in newly diagnosed patients with glioblastoma: correlation with MGMT promoter methylation status. J Clin Oncol. 2009;27:1275-1279.
    • (2009) J Clin Oncol , vol.27 , pp. 1275-1279
    • Brandes, A.A.1    Tosoni, A.2    Franceschi, E.3
  • 77
    • 73349121355 scopus 로고    scopus 로고
    • MGMT promoter methylation is prognostic but not predictive for outcome to adjuvant PCV chemotherapy in anaplastic oligodendroglial tumors: A report from EORTC Brain Tumor Group Study 26951
    • Van den Bent MJ, Dubbink HJ, Sanson M, et al. MGMT promoter methylation is prognostic but not predictive for outcome to adjuvant PCV chemotherapy in anaplastic oligodendroglial tumors: a report from EORTC Brain Tumor Group Study 26951. J Clin Oncol. 2009;27:5881-5886.
    • (2009) J Clin Oncol , vol.27 , pp. 5881-5886
    • Van Den Bent, M.J.1    Dubbink, H.J.2    Sanson, M.3
  • 78
    • 75149166496 scopus 로고    scopus 로고
    • MGMT promoter methylation in malignant gliomas: Ready for personalized medicine?
    • Weller M, Stupp R, Reifenberger G, et al. MGMT promoter methylation in malignant gliomas: ready for personalized medicine? Nat Rev Neurol. 2010;6:39-51.
    • (2010) Nat Rev Neurol , vol.6 , pp. 39-51
    • Weller, M.1    Stupp, R.2    Reifenberger, G.3
  • 79
    • 37549037792 scopus 로고    scopus 로고
    • MGMT immunohistochemical expression and promoter methylation in human glioblastoma
    • Rodriguez FJ, Thibodeau SN, Jenkins RB, et al. MGMT immunohistochemical expression and promoter methylation in human glioblastoma. Appl Immunohistochem Mol Morphol. 2008;16:59-65.
    • (2008) Appl Immunohistochem Mol Morphol , vol.16 , pp. 59-65
    • Rodriguez, F.J.1    Thibodeau, S.N.2    Jenkins, R.B.3
  • 80
    • 51249098488 scopus 로고    scopus 로고
    • Anti-O6-methylguanine-methyltransferase (MGMT) immunohistochemistry in glioblastoma multiforme: Observer variability and lack of association with patient survival impede its use as clinical biomarker
    • Preusser M, Janzer RC, Felsberg J, et al. Anti-O6-methylguanine- methyltransferase (MGMT) immunohistochemistry in glioblastoma multiforme: observer variability and lack of association with patient survival impede its use as clinical biomarker. Brain Pathol. 2008;18:520-532.
    • (2008) Brain Pathol , vol.18 , pp. 520-532
    • Preusser, M.1    Janzer, R.C.2    Felsberg, J.3
  • 81
    • 49249118859 scopus 로고    scopus 로고
    • Careful exclusion of non-neoplastic brain components is required for an appropriate evaluation of O6-methylguanine-DNA methyltransferase (MGMT) status in glioma: Relationship between immunohistochemistry and methylation analysis
    • Sasai K, Nodagashira M, Nishihara H, et al. Careful exclusion of non-neoplastic brain components is required for an appropriate evaluation of O6-methylguanine-DNA methyltransferase (MGMT) status in glioma: relationship between immunohistochemistry and methylation analysis. Am J Surg Pathol. 2008;32:1220-1227.
    • (2008) Am J Surg Pathol , vol.32 , pp. 1220-1227
    • Sasai, K.1    Nodagashira, M.2    Nishihara, H.3
  • 82
    • 38649088636 scopus 로고    scopus 로고
    • Variation of O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation in serial samples in glioblastoma
    • Parkinson JF, Wheeler HR, Clarkson A, et al. Variation of O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation in serial samples in glioblastoma. J Neurooncol. 2008;87:71-78.
    • (2008) J Neurooncol , vol.87 , pp. 71-78
    • Parkinson, J.F.1    Wheeler, H.R.2    Clarkson, A.3
  • 83
    • 70449371831 scopus 로고    scopus 로고
    • Novel molecular stereotactic biopsy procedures reveal intratumoral homogeneity of loss of heterozygosity of 1p/19q and TP53 mutations in World Health Organization grade II gliomas
    • Thon N, Eigenbrod S, Grasbon-Frodl EM, et al. Novel molecular stereotactic biopsy procedures reveal intratumoral homogeneity of loss of heterozygosity of 1p/19q and TP53 mutations in World Health Organization grade II gliomas. J Neuropathol Exp Neurol. 2009;68:1219-1228.
    • (2009) J Neuropathol Exp Neurol , vol.68 , pp. 1219-1228
    • Thon, N.1    Eigenbrod, S.2    Grasbon-Frodl, E.M.3
  • 84
    • 20044366163 scopus 로고    scopus 로고
    • Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
    • Stupp R, Mason WP, van den Bent MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 2005;352:987-996.
    • (2005) N Engl J Med , vol.352 , pp. 987-996
    • Stupp, R.1    Mason, W.P.2    Van Den Bent, M.J.3
  • 85
    • 27744606737 scopus 로고    scopus 로고
    • Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors
    • Mellinghoff IK, Wang MY, Vivanco I, et al. Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors. N Engl J Med. 2005;353:2012-2024.
    • (2005) N Engl J Med , vol.353 , pp. 2012-2024
    • Mellinghoff, I.K.1    Wang, M.Y.2    Vivanco, I.3
  • 86
    • 34250189213 scopus 로고    scopus 로고
    • Epidermal growth factor receptor variant III status defines clinically distinct subtypes of glioblastoma
    • Pellowski CE, Ballman KV, Furth AF, et al. Epidermal growth factor receptor variant III status defines clinically distinct subtypes of glioblastoma. J Clin Oncol. 2007;25:2288-2294.
    • (2007) J Clin Oncol , vol.25 , pp. 2288-2294
    • Pellowski, C.E.1    Ballman, K.V.2    Furth, A.F.3
  • 87
    • 67650688162 scopus 로고    scopus 로고
    • The PEPvIII-KLH (CDX-110) vaccine in glioblastoma multiforme patients
    • Heimberger AB, Sampson JH. The PEPvIII-KLH (CDX-110) vaccine in glioblastoma multiforme patients. Expert Opin Biol Ther. 2009;9:1087-1098.
    • (2009) Expert Opin Biol Ther , vol.9 , pp. 1087-1098
    • Heimberger, A.B.1    Sampson, J.H.2
  • 88
    • 64849098267 scopus 로고    scopus 로고
    • Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha
    • Zhao S, Lin Y, Xu W, et al. Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha. Science. 2009;324:261-265.
    • (2009) Science , vol.324 , pp. 261-265
    • Zhao, S.1    Lin, Y.2    Xu, W.3
  • 89
    • 0037381008 scopus 로고    scopus 로고
    • Gene expression-based classification of malignant gliomas correlates better with survival than histological classification
    • Nutt CL, Mani DR, Betensky RA, et al. Gene expression-based classification of malignant gliomas correlates better with survival than histological classification. Cancer Res. 2003;63:1602-1607.
    • (2003) Cancer Res , vol.63 , pp. 1602-1607
    • Nutt, C.L.1    Mani, D.R.2    Betensky, R.A.3
  • 90
    • 20144376240 scopus 로고    scopus 로고
    • Gene expression profiling and genetic markers in glioblastoma survival
    • Rich JN, Hans C, Jones B, et al. Gene expression profiling and genetic markers in glioblastoma survival. Cancer Res. 2005;65: 4051-4058.
    • (2005) Cancer Res , vol.65 , pp. 4051-4058
    • Rich, J.N.1    Hans, C.2    Jones, B.3
  • 91
    • 4644313275 scopus 로고    scopus 로고
    • Gene expression profiling of gliomas strongly predicts survival
    • Freije WA, Castro-Vargas FE, Fang Z, et al. Gene expression profiling of gliomas strongly predicts survival. Cancer Res. 2004;64:6503-6510.
    • (2004) Cancer Res , vol.64 , pp. 6503-6510
    • Freije, W.A.1    Castro-Vargas, F.E.2    Fang, Z.3
  • 92
    • 33644820339 scopus 로고    scopus 로고
    • Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
    • Phillips HS, Kharbanda S, Chen R, et al. Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell. 2006;9:157-173.
    • (2006) Cancer Cell , vol.9 , pp. 157-173
    • Phillips, H.S.1    Kharbanda, S.2    Chen, R.3
  • 93
    • 75749115909 scopus 로고    scopus 로고
    • A multigene predictor of outcome in glioblastoma
    • Colman H, Zhang L, Sulman EP, et al. A multigene predictor of outcome in glioblastoma. Neuro-Oncology. 2010;12: 49-57.
    • (2010) Neuro-Oncology , vol.12 , pp. 49-57
    • Colman, H.1    Zhang, L.2    Sulman, E.P.3
  • 94
    • 73649123907 scopus 로고    scopus 로고
    • Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH-1, EGFR, and NF1
    • Verhaak RGW, Hoadley KA, Purdom E, et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH-1, EGFR, and NF1. Cancer Cell. 2010;17:98-110.
    • (2010) Cancer Cell , vol.17 , pp. 98-110
    • Verhaak, R.G.W.1    Hoadley, K.A.2    Purdom, E.3
  • 95
    • 33845317573 scopus 로고    scopus 로고
    • Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
    • Bao S, Wu Q, McLendon RE, et al. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature. 2006;444:756-760.
    • (2006) Nature , vol.444 , pp. 756-760
    • Bao, S.1    Wu, Q.2    McLendon, R.E.3
  • 96
    • 42949149114 scopus 로고    scopus 로고
    • Glioblastomaderived stem cell-enriched cultures from distinct subgroups according to molecular and phenotypic criteria
    • Gunther HS, Schmidt NO, Phillips HS, et al. Glioblastomaderived stem cell-enriched cultures from distinct subgroups according to molecular and phenotypic criteria. Oncogene. 2008;27: 2897-2909.
    • (2008) Oncogene , vol.27 , pp. 2897-2909
    • Gunther, H.S.1    Schmidt, N.O.2    Phillips, H.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.