Effects of gadolinium chloride and glycine on hepatic and pancreatic tissue damage in alcoholic pancreatitis

Pancreas

Volumn 39, Issue 4, 2010, Pages 502-509

  Schneider, Lutz ^a   Hackert, Thilo ^a   Longerich, Thomas ^a   Hartwig, Werner ^a   Fritz, Stefan ^a   Krych, Ralf ^a   Fortunato, Franco ^a   Gebhard, Martha Maria ^a   Werner, Jens ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Acute pancreatitis; Alcohol; Kupffer cell

Indexed keywords

ALCOHOL; GADOLINIUM CHLORIDE; GLYCINE;

ACUTE HEMORRHAGIC PANCREATITIS; ALCOHOLIC PANCREATITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIET; EXPOSURE; FEEDING; KUPFFER CELL; LIVER; LIVER CIRCULATION; LIVER INJURY; MACROPHAGE; MALE; MICROCIRCULATION; MORPHOLOGY; NONHUMAN; PANCREAS; PANCREAS INJURY; PRIORITY JOURNAL; RAT;

ANALYSIS OF VARIANCE; ANIMALS; ETHANOL; GADOLINIUM; GLYCINE; GLYCINE AGENTS; LIVER; LIVER CIRCULATION; LIVER DISEASES; MALE; PANCREAS; PANCREATITIS, ACUTE NECROTIZING; PANCREATITIS, ALCOHOLIC; RATS; RATS, WISTAR;

EID: 77951757009     PISSN: 08853177     EISSN: None     Source Type: Journal    
DOI: 10.1097/MPA.0b013e3181bd6470     Document Type: Article

References (41)

1. Werner J, Feuerbach S, Uhl W, et al. Management of acute pancreatitis: from surgery to interventional intensive care. Gut. 2005;54:426-436.
2. Klar E, Werner J. New pathophysiologic knowledge about acute pancreatitis. Chirurg. 2000;71:253-264.
3. Buchler MW, Gloor B, Muller CA, et al. Acute necrotizing pancreatitis: treatment strategy according to the status of infection. Ann Surg. 2000;232:619-626.
4. Tenner S, Sica G, Hughes M, et al. Relationship of necrosis to organ failure in severe acute pancreatitis. Gastroenterology. 1997;113: 899-903.
5. Lankisch PG, Assmus C, Pflichthofer D, et al. Which etiology causes the most severe acute pancreatitis? Int J Pancreatol. 1999;26:55-57.
6. Lankisch PG, Pflichthofer D, Lehnick D. Acute pancreatitis: which patient is most at risk? Pancreas. 1999;19:321-324.
7. Singh M, Simsek H. Ethanol and the pancreas. Current status. Gastroenterology. 1990;98:1051-1062.
8. Schneider L, Pietschmann M, Hartwig W, et al. Alcohol pretreatment increases hepatic and pulmonary injury in experimental pancreatitis. Pancreatology. 2009;9(3):258-266.
9. Closa D, Sabater L, Fernandez-Cruz L, et al. Activation of alveolar macrophages in lung injury associated with experimental acute pancreatitis is mediated by the liver. Ann Surg. 1999;229:230-236.
10. Gross V, Leser HG, Heinisch A, et al. Inflammatory mediators and cytokinesVnew aspects of the pathophysiology and assessment of severity of acute pancreatitis? Hepatogastroenterology. 1993;40: 522-530.
11. Johnson CD. Platelet-activating factor and platelet-activating factor antagonists in acute pancreatitis. Dig Surg. 1999;16:93-101.
12. Klar E, Schratt W, Foitzik T, et al. Impact of microcirculatory flow pattern changes on the development of acute edematous and necrotizing pancreatitis in rabbit pancreas. Dig Dis Sci. 1994;39:2639-2644.
13. Werner J, Z'Graggen K, Fernandez-del Castillo C, et al. Specific therapy for local and systemic complications of acute pancreatitis with monoclonal antibodies against ICAM-1. Ann Surg. 1999;229: 834-840; discussion 841-842.
14. Gloor B, Blinman TA, Rigberg DA, et al. Kupffer cell blockade reduces hepatic and systemic cytokine levels and lung injury in hemorrhagic pancreatitis in rats. Pancreas. 2000;21:414-420.
15. Ikejima K, Iimuro Y, Forman DT, et al. A diet containing glycine improves survival in endotoxin shock in the rat. Am J Physiol. 1996;271:G97YG103. (Pubitemid 26299731)
16. Lemasters JJ, Thurman RG. Reperfusion injury after liver preservation for transplantation. Annu Rev Pharmacol Toxicol. 1997;37:327-338.
17. Zhong Z, Jones S, Thurman RG. Glycine minimizes reperfusion injury in a low-flow, reflow liver perfusion model in the rat. Am J Physiol. 1996;270:G332YG338.
18. Schemmer P, Bradford BU, Rose ML, et al. Intravenous glycine improves survival in rat liver transplantation. Am J Physiol. 1999;276: G924YG932.
19. Jahnke C, Mehrabi A, Golling M, et al. Evaluation of microperfusion disturbances in the transplanted liver after Kupffer cell destruction using GdCl3: an experimental porcine study. Transplant Proc. 2006;38:1588-1595.
20. Jorgensen PF, Gotzinger P, Scholz T, et al. The role of Kupffer cell inhibition in porcine endotoxemia. Shock. 2001;16:466-472.
21. Kleiner DE, Brunt EM, Van Natta M, et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology. 2005;41:1313-1321.
22. Schmidt J, Rattner DW, Lewandrowski K, et al. A better model of acute pancreatitis for evaluating therapy. Ann Surg. 1992;215:44-56.
23. Schemmer P, Liang R, Kincius M, et al. Taurine improves graft survival after experimental liver transplantation. Liver Transpl. 2005;11:950-959.
24. Granger DN, Benoit JN, Suzuki M, et al. Leukocyte adherence to venular endothelium during ischemia-reperfusion. Am J Physiol. 1989;257:G683YG688.
25. Massberg S, Enders G, Leiderer R, et al. Platelet-endothelial cell interactions during ischemia/reperfusion: the role of P-selectin. Blood. 1998;92:507-515.
26. Horie Y, Kato S, Ohki E, et al. Role of endothelin in endotoxin-induced hepatic microvascular dysfunction in rats fed chronically with ethanol. J Gastroenterol Hepatol. 2001;16:916-922.
27. Ohki E, Kato S, Horie Y, et al. Chronic ethanol consumption enhances endotoxin induced hepatic sinusoidal leukocyte adhesion. Alcohol Clin Exp Res. 1996;20:350AY355A.
28. Bauer I, Bauer M, Pannen BH, et al. Chronic ethanol consumption exacerbates liver injury following hemorrhagic shock: role of sinusoidal perfusion failure. Shock. 1995;4:324-331.
29. Bauer M, Paquette NC, Zhang JX, et al. Chronic ethanol consumption increases hepatic sinusoidal contractile response to endothelin-1 in the rat. Hepatology. 1995;22:1565-1576.
30. de la MHP, Lieber CS, DeCarli LM, et al. Models of alcoholic liver disease in rodents: a critical evaluation. Alcohol Clin Exp Res. 2001;25:254SY261S.
31. Karaa A, Kamoun WS, Clemens MG. Chronic ethanol sensitizes the liver to endotoxin via effects on endothelial nitric oxide synthase regulation. Shock. 2005;24:447-454.
32. Enomoto N, Ikejima K, Bradford B, et al. Alcohol causes both tolerance and sensitization of rat Kupffer cells via mechanisms dependent on endotoxin. Gastroenterology. 1998;115:443-451.
33. Mathurin P, Deng QG, Keshavarzian A, et al. Exacerbation of alcoholic liver injury by enteral endotoxin in rats. Hepatology. 2000;32: 1008-1017.
34. Murr MM, Yang J, Fier A, et al. Regulation of Kupffer cell TNF gene expression during experimental acute pancreatitis: the role of p38-MAPK, ERK1/2, SAPK/JNK, and NF-kappaB. J Gastrointest Surg. 2003;7:20-25.
35. Giakoustidis DE, Iliadis S, Tsantilas D, et al. Blockade of Kupffer cells by gadolinium chloride reduces lipid peroxidation and protects liver from ischemia/reperfusion injury. Hepatogastroenterology. 2003;50:1587-1592.
36. Schauer RJ, Bilzer M, Kalmuk S, et al. Microcirculatory failure after rat liver transplantation is related to Kupffer cell-derived oxidant stress but not involved in early graft dysfunction. Transplantation. 2001;72: 1692-1699.
37. Croner RS, Kulu Y, Hoerer E, et al. Intravenous glycine after cecal ligation and puncture has no effect on impaired hepatic microperfusion, leukocyte adhesion, and mortality in septic rats. Microvasc Res. 2005;69:71-78.
38. Luntz SP, Unnebrink K, Seibert-Grafe M, et al. HEGPOL: randomized, placebo controlled, multicenter, double-blind clinical trial to investigate hepatoprotective effects of glycine in the postoperative phase of liver transplantation [ISRCTN69350312]. BMC Surg. 2005;5:18.
39. Rentsch M, Puellmann K, Sirek S, et al. Benefit of Kupffer cell modulation with glycine versus Kupffer cell depletion after liver transplantation in the rat: effects on postischemic reperfusion injury, apoptotic cell death graft regeneration and survival. Transpl Int. 2005;18:1079-1089.
40. Hardonk MJ, Dijkhuis FW, Hulstaert CE, et al. Heterogeneity of rat liver and spleen macrophages in gadolinium chlorideYinduced elimination and repopulation. J Leukoc Biol. 1992;52:296-302.
41. den Butter G, Lindell SL, Sumimoto R, et al. Effect of glycine in dog and rat liver transplantation. Transplantation. 1993;56:817-822.