Chronic ethanol consumption enhances endotoxin induced hepatic sinusoidal leukocyte adhesion

Alcoholism: Clinical and Experimental Research

Volumn 20, Issue 9 SUPPL., 1996, Pages

  Ohki, E ^a   Kato, S ^a   Horie, Y ^a   Mizukami, T ^a   Tamai, H ^a   Yokoyama, H ^a   Ito, D ^a   Fukuda, M ^a   Suzuki, H ^a   Kurose, I ^a   Ishii, H ^a  

^a KEIO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; ENDOTOXIN; TUMOR NECROSIS FACTOR ALPHA;

ALCOHOL CONSUMPTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CELL ADHESION; CHRONIC DISEASE; CONFERENCE PAPER; DIETARY INTAKE; ENERGY EXPENDITURE; FLUOROGRAPHY; LEUKOCYTE ADHERENCE; LIVER DISEASE; LIVER SINUSOID; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BLOOD FLOW VELOCITY; CAPILLARY PERMEABILITY; ENDOTHELIUM, VASCULAR; LEUKOCYTE ADHERENCE INHIBITION TEST; LEUKOCYTES; LIPOPOLYSACCHARIDES; LIVER; LIVER CIRRHOSIS, ALCOHOLIC; MALE; MICROSCOPY, FLUORESCENCE; PORTAL PRESSURE; RATS; RATS, WISTAR; TUMOR NECROSIS FACTOR-ALPHA; VENULES;

EID: 0030460189     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1530-0277.1996.tb01171.x     Document Type: Conference Paper

References (18)

1. Bode C, Kugler V, Bode JC: Endotoxemia in patients with alcoholic and non-alcoholic cirrhosis and in subjects with no evidence of chronic liver disease following acute alcohol excess. J Hepatol 4:8-14, 1987
2. Fukui H, Brauner B, Bode JC, Bode C: Plasma endotoxin concentrations in patients with alcoholic and non-alcoholic liver disease: Reevaluation with an improved chromogenic assay. J Hepatol 12:162-169, 1991
3. Adachi Y, Moore LE, Bradford BU, Gao W, Thurman RG: Antibiotics prevent liver injury in rats following long-term exposure to ethanol. Gastroenterology 108:218-224, 1995
4. Bradfold BU, Misra UK, Thurman RG: Kupffer cells are required for the swift increase in alcohol metabolism. Res Commun Subst Abuse 14:1-6, 1993
5. Spitzer JA, Nelson KM, Fish RE: Time course of changes in glycogenesis from various precursors in chronically endotoxinemic rats. Metabolism 34:842-849, 1985
6. Arai M, Nakano S, Okuno F, Hirano Y, Sujita K, Kobayashi T, Ishii H, Tsuchiya M: Endotoxin-induced hypercoagulabity: Possible aggravating factor of alcoholic liver disease. Hepatology 9(6):846-851, 1989
7. Kato M, Torisu M: Potential role of Kupffer cells in initiating liver injury during endotoxemia. J Exp Pathol 4:141-161, 1989
8. Hansen J, Cherwitz DL, Allen JI: The role of tumor necrosing factor-α in acute endotoxin-induced hepatotoxity in ethanol-fed rats. Hepatology 20:461-474, 1994
9. Doi F, Goya T, Torisu M: Potential role of hepatic macrophages in neutrophil-mediated liver injury in rats with sepsis. Hepatology 17:1086-1094, 1993
10. Hamamatu H: Quantitative analysis of erythrocyte velocity in rat liver after acute ethanol administration. Jpn J Alcohol Stud Drug Depend 28(6):467-482, 1993
11. Horie Y, Kato S, Hamamatsu H, Kurose I, Ishii H: Effect of lipopolysaccharides on erythrocyte velocity in rat liver, (submitted)
12. Lieber CS, Decarli LM: Animal models of ethanol dependence and liver injury in rats and baboons. Fed Proc 35:1232-1236, 1976
13. Zimmerhackl B, Parekh N, Brinkhaus H, Steinhausen M: The use of fluorescent labeled erythrocytes for intravital investigation of flow and local hematocrit in glomerular capillaries in the rat. Int J Microcirc Clin Exp 2:119-129, 1983
14. Morisaki T, Goya T, Toh H, Nishihara K: The anti Mac-1 monoclonal antibody inhibits neutrophil sequestration in lung and liver in septic murine model. Clin Immunol Immunopathol 61:365-375, 1991
15. Mackay CR, Imhof BA: Cell adhesion in the immune system. Immunol Today 14:99-102, 1993
16. Kurose I, Anderson DC, Miyasaka M, Tamatani T, Paulson CJ, Todd RF, Russche JR, Granger DM: Molecular determinants of reperfusion induced leukocyte adhesion and vascular protein leakage. Circ Res 74:336-343, 1994
17. Adams DH, Burra P, Hubscer SG, Elias E, Newman W: Endothelial activation and circulating vascular adhesion molecules in alcoholic liver disease. Hepatology 19:588-594, 1994
18. Fukui H, Kitano H, Morimura M, Kikuchi E, Matumoto M, Tujita S, Kinoshita K, Mtsumoto M, Okamoto Y, Tadasu T: Metabolic fate of endotoxin and blood tumor necrosing factor levels in rats with acute and chronic alcohol loading. Alcohol Alcohol 28:65-70, 1993