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Volumn 37, Issue 3, 2010, Pages 1191-1195

High Mobility Group Box 1: A potential therapeutic target for systemic lupus erythematosus

Author keywords

Autoantibodies; Autoimmune; HMGB1; Nucleosomes; Systemic lupus erythematosus; Therapeutic target

Indexed keywords

ADVANCED GLYCATION END PRODUCT; HIGH MOBILITY GROUP B1 PROTEIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY IA 4; PROTEIN ANTIBODY; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG; DNA;

EID: 77951733201     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-009-9485-7     Document Type: Review
Times cited : (23)

References (44)
  • 1
    • 47149116300 scopus 로고    scopus 로고
    • Type 17 T-helper cells might be a promising therapeutic target for systemic lupus erythematosus
    • Pan HF, Ye DQ, Li XP (2008) Type 17 T-helper cells might be a promising therapeutic target for systemic lupus erythematosus. Nat Clin Pract Rheumatol 4:352-353
    • (2008) Nat Clin Pract Rheumatol , vol.4 , pp. 352-353
    • Pan, H.F.1    Ye, D.Q.2    Li, X.P.3
  • 2
    • 45649083400 scopus 로고    scopus 로고
    • Radix astragali: A promising new treatment option for systemic lupus erythematosus
    • doi:10.1016/j.mehy.2008. 03.011
    • Pan HF, Fang XH, Li WX et al (2008) Radix astragali: A promising new treatment option for systemic lupus erythematosus. Med Hypotheses 71:311-312. doi:10.1016/j.mehy.2008. 03.011
    • (2008) Med Hypotheses , vol.71 , pp. 311-312
    • Pan, H.F.1    Fang, X.H.2    Li, W.X.3
  • 3
    • 33744945033 scopus 로고    scopus 로고
    • Mechanisms of disease: The complement system and the pathogenesis of systemic lupus erythematosus
    • doi:10.1038/ncprheum0191
    • Cook HT, BottoM(2006) Mechanisms of disease: The complement system and the pathogenesis of systemic lupus erythematosus. Nat Clin Pract Rheumatol 2:330-337. doi:10.1038/ncprheum0191
    • (2006) Nat Clin Pract Rheumatol , vol.2 , pp. 330-337
    • Cook, H.T.1    Botto, M.2
  • 4
    • 41149168670 scopus 로고    scopus 로고
    • High mobility group box 1 in the pathogenesis of inflammatory and autoimmune diseases
    • Voll RE, Urbonaviciute V, Herrmann M et al (2008) High mobility group box 1 in the pathogenesis of inflammatory and autoimmune diseases. Isr Med Assoc J 10:26-28
    • (2008) Isr Med Assoc J , vol.10 , pp. 26-28
    • Voll, R.E.1    Urbonaviciute, V.2    Herrmann, M.3
  • 5
    • 42449084910 scopus 로고    scopus 로고
    • Expression of high mobility group protein 1 in the sera of patients and mice with systemic lupus erythematosus
    • doi:10.1136/ ard. 2007.074484
    • Jiang W, Pisetsky DS (2008) Expression of high mobility group protein 1 in the sera of patients and mice with systemic lupus erythematosus. Ann Rheum Dis 67:727-728. doi:10.1136/ ard.2007.074484
    • (2008) Ann Rheum Dis , vol.67 , pp. 727-728
    • Jiang, W.1    Pisetsky, D.S.2
  • 6
    • 54049128417 scopus 로고    scopus 로고
    • Pathogenic anti-DNA antibodies modulate gene expression in mesangial cells: Involvement of HMGB1 in anti-DNA antibody-induced renal injury
    • doi:10.1016/j.imlet.2008.08.007
    • Qing X, Pitashny M, Thomas DB et al (2008) Pathogenic anti-DNA antibodies modulate gene expression in mesangial cells: Involvement of HMGB1 in anti-DNA antibody-induced renal injury. Immunol Lett 121:61-73. doi:10.1016/j.imlet.2008. 08.007
    • (2008) Immunol Lett , vol.121 , pp. 61-73
    • Qing, X.1    Pitashny, M.2    Thomas, D.B.3
  • 7
    • 0015857760 scopus 로고
    • A new group of chromatin-associated proteins with a high content of acidic and basic amino acids
    • doi:10.1111/j.1432-1033.1973.tb03026.x
    • Goodwin GH, Sanders C, Johns EW (1973) A new group of chromatin-associated proteins with a high content of acidic and basic amino acids. Eur J Biochem 38:14-19. doi:10.1111/j.1432-1033.1973.tb03026.x
    • (1973) Eur J Biochem , vol.38 , pp. 14-19
    • Goodwin, G.H.1    Sanders, C.2    Johns, E.W.3
  • 8
    • 0030586235 scopus 로고    scopus 로고
    • The active gene that encodes human high mobility group 1 protein (HMG1) contains introns and maps to chromosome 13
    • doi:10.1006/geno.1996.0369
    • Ferrari S, Finelli P, Rocchi M et al (1996) The active gene that encodes human high mobility group 1 protein (HMG1) contains introns and maps to chromosome 13. Genomics 35:367-371. doi:10.1006/geno.1996.0369
    • (1996) Genomics , vol.35 , pp. 367-371
    • Ferrari, S.1    Finelli, P.2    Rocchi, M.3
  • 9
    • 0027411094 scopus 로고
    • A retropseudogene for non-histone chromosomal protein HMG-1
    • Stros M, Dixon GH (1993) A retropseudogene for non-histone chromosomal protein HMG-1. Biochim Biophys Acta 1172:231-235
    • (1993) Biochim Biophys Acta , vol.1172 , pp. 231-235
    • Stros, M.1    Dixon, G.H.2
  • 10
    • 0024590341 scopus 로고
    • A human placental cDNA clone that encodes nonhistone chromosomal protein HMG-1
    • doi:10.1093/nar/ 17.3.1197
    • Wen L, Huang JK, Johnson BH et al (1989) A human placental cDNA clone that encodes nonhistone chromosomal protein HMG-1. Nucleic Acids Res 17:1197-1214. doi:10.1093/nar/ 17.3.1197
    • (1989) Nucleic Acids Res , vol.17 , pp. 1197-1214
    • Wen, L.1    Huang, J.K.2    Johnson, B.H.3
  • 11
    • 0019335486 scopus 로고
    • The primary structures of non-histone chromosomal proteins HMG 1 and 2
    • doi:10.1016/0014-5793(80)80453-4
    • Walker JM, Gooderham K, Hastings JR et al (1980) The primary structures of non-histone chromosomal proteins HMG 1 and 2. FEBS Lett 122:264-270. doi:10.1016/0014-5793(80)80453-4
    • (1980) FEBS Lett , vol.122 , pp. 264-270
    • Walker, J.M.1    Gooderham, K.2    Hastings, J.R.3
  • 12
    • 0023651437 scopus 로고
    • Nucleotide sequence of rat liver HMG1 cDNA
    • doi:10.1093/ nar/15.21.9077
    • Paonessa G, Frank R, Cortese R (1987) Nucleotide sequence of rat liver HMG1 cDNA. Nucleic Acids Res 15:9077. doi:10.1093/ nar/15.21.9077
    • (1987) Nucleic Acids Res , vol.15 , pp. 9077
    • Paonessa, G.1    Frank, R.2    Cortese, R.3
  • 13
    • 0026770702 scopus 로고
    • Nucleotide sequence of a mouse cDNA encoding the nonhistone chromosomal high mobility group protein-1 (HMG1)
    • doi:10.1093/nar/20.13.3516
    • Yotov WV, St-Arnaud R (1992) Nucleotide sequence of a mouse cDNA encoding the nonhistone chromosomal high mobility group protein-1 (HMG1). Nucleic Acids Res 20:3516. doi:10.1093/nar/20.13.3516
    • (1992) Nucleic Acids Res , vol.20 , pp. 3516
    • Yotov, W.V.1    St-Arnaud, R.2
  • 14
    • 1542285224 scopus 로고    scopus 로고
    • Amphoterin as an extracellular regulator of cell motility: From discovery to disease
    • doi:10.1111/j.1365-2796.2003.01301.x
    • Huttunen HJ, Rauvala H (2004) Amphoterin as an extracellular regulator of cell motility: From discovery to disease. J Intern Med 255:351-366. doi:10.1111/j.1365-2796.2003.01301.x
    • (2004) J Intern Med , vol.255 , pp. 351-366
    • Huttunen, H.J.1    Rauvala, H.2
  • 15
    • 41049117932 scopus 로고    scopus 로고
    • Convergence and amplification of toll-like receptor (TLR) and receptor for advanced glycation end products (RAGE) signaling pathways via high mobility group B1 (HMGB1)
    • doi:10.1007/s10456-008-9093-5
    • van Beijnum JR, Buurman WA, Griffioen AW (2008) Convergence and amplification of toll-like receptor (TLR) and receptor for advanced glycation end products (RAGE) signaling pathways via high mobility group B1 (HMGB1). Angiogenesis 11:91-99. doi:10.1007/s10456-008-9093-5
    • (2008) Angiogenesis , vol.11 , pp. 91-99
    • Van Beijnum, J.R.1    Buurman, W.A.2    Griffioen, A.W.3
  • 16
    • 22144447819 scopus 로고    scopus 로고
    • The cytokine activity of HMGB1
    • doi:10.1189/jlb.1104648
    • Yang H, Wang H, Czura CJ et al (2005) The cytokine activity of HMGB1. J Leukoc Biol 78:1-8. doi:10.1189/jlb.1104648
    • (2005) J Leukoc Biol , vol.78 , pp. 1-8
    • Yang, H.1    Wang, H.2    Czura, C.J.3
  • 17
    • 0024469223 scopus 로고
    • Tissue specificity of nucleo-cytoplasmic distribution of HMG1 and HMG2 proteins and their probable functions
    • doi:10.1111/j.1432-1033.1989.tb15116.x
    • Mosevitsky MI, Novitskaya VA, Iogannsen MG et al (1989) Tissue specificity of nucleo-cytoplasmic distribution of HMG1 and HMG2 proteins and their probable functions. Eur J Biochem 185:303-310. doi:10.1111/j.1432-1033. 1989.tb15116.x
    • (1989) Eur J Biochem , vol.185 , pp. 303-310
    • Mosevitsky, M.I.1    Novitskaya, V.A.2    Iogannsen, M.G.3
  • 18
    • 17144376810 scopus 로고    scopus 로고
    • High-mobility group box 1 protein (HMGB1): Nuclear weapon in the immune arsenal
    • doi:10.1038/nri1594
    • Lotze MT, Tracey KJ (2005) High-mobility group box 1 protein (HMGB1): Nuclear weapon in the immune arsenal. Nat Rev Immunol 5:331-342. doi:10.1038/nri1594
    • (2005) Nat Rev Immunol , vol.5 , pp. 331-342
    • Lotze, M.T.1    Tracey, K.J.2
  • 19
    • 0142137129 scopus 로고    scopus 로고
    • Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion
    • doi:10.1093/emboj/cdg516
    • Bonaldi T, Talamo F, Scaffidi P et al (2003) Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion. EMBO J 22:5551-5560. doi:10.1093/emboj/cdg516
    • (2003) EMBO J , vol.22 , pp. 5551-5560
    • Bonaldi, T.1    Talamo, F.2    Scaffidi, P.3
  • 20
    • 0033538467 scopus 로고    scopus 로고
    • HMG-1 as a late mediator of endotoxin lethality in mice
    • doi:10.1126/science.285.5425.248
    • Wang H, Bloom O, Zhang M et al (1999) HMG-1 as a late mediator of endotoxin lethality in mice. Science 285:248-251. doi:10.1126/science.285.5425. 248
    • (1999) Science , vol.285 , pp. 248-251
    • Wang, H.1    Bloom, O.2    Zhang, M.3
  • 21
    • 33845333359 scopus 로고    scopus 로고
    • The extracellular release of HMGB1 during apoptotic cell death
    • doi:10.1152/ajpcell.00616.2005
    • Bell CW, Jiang W, Reich CF et al (2006) The extracellular release of HMGB1 during apoptotic cell death. Am J Physiol Cell Physiol 291:C1318-C1325. doi:10.1152/ajpcell.00616.2005
    • (2006) Am J Physiol Cell Physiol , vol.291
    • Bell, C.W.1    Jiang, W.2    Reich, C.F.3
  • 22
    • 34248229237 scopus 로고    scopus 로고
    • The relationship between apoptosis and HMGB1 release from murine macrophages stimulated with LPS or poly (I:C)
    • Jiang W, Bell CW, Pisetsky DS (2007) The relationship between apoptosis and HMGB1 release from murine macrophages stimulated with LPS or poly (I:C). J Immunol 178:6495-6503
    • (2007) J Immunol , vol.178 , pp. 6495-6503
    • Jiang, W.1    Bell, C.W.2    Pisetsky, D.S.3
  • 23
    • 0037038819 scopus 로고    scopus 로고
    • Receptor for advanced glycation endproducts: A multiligand receptor magnifying cell stress in diverse pathologic settings
    • doi:10.1016/S0169-409X(02)00160-6
    • Stern D, Yan SD, Yan SF et al (2002) Receptor for advanced glycation endproducts: A multiligand receptor magnifying cell stress in diverse pathologic settings. Adv Drug Deliv Rev 54:1615-1625. doi:10.1016/S0169-409X(02)00160-6
    • (2002) Adv Drug Deliv Rev , vol.54 , pp. 1615-1625
    • Stern, D.1    Yan, S.D.2    Yan, S.F.3
  • 24
    • 0035316744 scopus 로고    scopus 로고
    • HMG-1 rediscovered as a cytokine
    • doi:10.1097/00024382-200115040-00001
    • Yang H, Wang H, Tracey KJ (2001) HMG-1 rediscovered as a cytokine. Shock 15:247-253. doi:10.1097/00024382-200115040-00001
    • (2001) Shock , vol.15 , pp. 247-253
    • Yang, H.1    Wang, H.2    Tracey, K.J.3
  • 25
    • 0035891570 scopus 로고    scopus 로고
    • HMGB1 as a late mediator of lethal systemic inflammation
    • Wang H, Yang H, Czura CJ et al (2001) HMGB1 as a late mediator of lethal systemic inflammation. Am J Respir Crit Care Med 164:1768-1773
    • (2001) Am J Respir Crit Care Med , vol.164 , pp. 1768-1773
    • Wang, H.1    Yang, H.2    Czura, C.J.3
  • 26
    • 0036957367 scopus 로고    scopus 로고
    • HMGB1 as a cytokine and therapeutic target
    • doi:10.1179/096805102125001091
    • Yang H, Wang H, Czura CJ et al (2002) HMGB1 as a cytokine and therapeutic target. J Endotoxin Res 8:469-472. doi:10.1179/ 096805102125001091
    • (2002) J Endotoxin Res , vol.8 , pp. 469-472
    • Yang, H.1    Wang, H.2    Czura, C.J.3
  • 27
    • 55549128746 scopus 로고    scopus 로고
    • Highmobility group box protein 1 (HMGB1): An alarmin mediating the pathogenesis of rheumatic disease
    • doi:10.1186/ar2440
    • Pisetsky DS, Erlandsson-Harris H, Andersson U (2008) Highmobility group box protein 1 (HMGB1): An alarmin mediating the pathogenesis of rheumatic disease. Arthritis Res Ther 10:209. doi:10.1186/ar2440
    • (2008) Arthritis Res Ther , vol.10 , pp. 209
    • Pisetsky, D.S.1    Erlandsson-Harris, H.2    Andersson, U.3
  • 28
    • 70349982431 scopus 로고    scopus 로고
    • HMGB1 mediates endogenous TLR2 activation and brain tumor regression
    • doi:10.1371/journal.pmed.1000010
    • Curtin JF, Liu N, Candolfi M et al (2009) HMGB1 mediates endogenous TLR2 activation and brain tumor regression. PLoS Med 6:e10. doi:10.1371/journal.pmed. 1000010
    • (2009) PLoS Med , vol.6
    • Curtin, J.F.1    Liu, N.2    Candolfi, M.3
  • 29
    • 33747751590 scopus 로고    scopus 로고
    • Alarmin(g) news about danger: Workshop on innate danger signals and HMGB1
    • Harris HE, Raucci A (2006) Alarmin(g) news about danger: Workshop on innate danger signals and HMGB1. EMBO Rep 7:774-778
    • (2006) EMBO Rep , vol.7 , pp. 774-778
    • Harris, H.E.1    Raucci, A.2
  • 30
    • 0038681182 scopus 로고    scopus 로고
    • Successful treatment of collagen-induced arthritis in mice and rats by targeting extracellular high mobility group box chromosomal protein 1 activity
    • doi:10.1002/art.11161
    • Kokkola R, Li J, Sundberg E et al (2003) Successful treatment of collagen-induced arthritis in mice and rats by targeting extracellular high mobility group box chromosomal protein 1 activity. Arthritis Rheum 48:2052-2058. doi:10.1002/art.11161
    • (2003) Arthritis Rheum , vol.48 , pp. 2052-2058
    • Kokkola, R.1    Li, J.2    Sundberg, E.3
  • 31
    • 0037386810 scopus 로고    scopus 로고
    • High mobility group box chromosomal protein 1 plays a role in the pathogenesis of rheumatoid arthritis as a novel cytokine
    • doi:10.1002/art.10859
    • Taniguchi N, Kawahara K, Yone K et al (2003) High mobility group box chromosomal protein 1 plays a role in the pathogenesis of rheumatoid arthritis as a novel cytokine. Arthritis Rheum 48:971-981. doi:10.1002/art.10859
    • (2003) Arthritis Rheum , vol.48 , pp. 971-981
    • Taniguchi, N.1    Kawahara, K.2    Yone, K.3
  • 32
    • 33845880868 scopus 로고    scopus 로고
    • Factors masking HMGB1 in human serum and plasma
    • doi:10.1189/jlb.0306196
    • Urbonaviciute V, Furnrohr BG, Weber C et al (2007) Factors masking HMGB1 in human serum and plasma. J Leukoc Biol 81:67-74. doi:10.1189/jlb.0306196
    • (2007) J Leukoc Biol , vol.81 , pp. 67-74
    • Urbonaviciute, V.1    Furnrohr, B.G.2    Weber, C.3
  • 33
    • 59649126956 scopus 로고    scopus 로고
    • Induction of inflammatory and immune responses by HMGB1-nucleosome complexes: Implications for the pathogenesis of SLE
    • doi:10.1084/jem.20081165
    • Urbonaviciute V, Fürnrohr BG, Meister S et al (2008) Induction of inflammatory and immune responses by HMGB1-nucleosome complexes: Implications for the pathogenesis of SLE. J Exp Med. doi:10.1084/jem.20081165
    • (2008) J Exp Med
    • Urbonaviciute, V.1    Fürnrohr, B.G.2    Meister, S.3
  • 34
    • 0037062934 scopus 로고    scopus 로고
    • Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
    • doi:10.1038/nature00858
    • Scaffidi P, Misteli T, Bianchi ME (2002) Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature 418:191-195. doi:10.1038/nature00858
    • (2002) Nature , vol.418 , pp. 191-195
    • Scaffidi, P.1    Misteli, T.2    Bianchi, M.E.3
  • 35
    • 0028138369 scopus 로고
    • Antibodies to high mobility group proteins in systemic sclerosis
    • Ayer LM, Senecal JL, Martin L et al (1994) Antibodies to high mobility group proteins in systemic sclerosis. J Rheumatol 21:2071-2075
    • (1994) J Rheumatol , vol.21 , pp. 2071-2075
    • Ayer, L.M.1    Senecal, J.L.2    Martin, L.3
  • 36
    • 0033782379 scopus 로고    scopus 로고
    • Relationship between sex and antibodies to high mobility group proteins 1 and 2 in juvenile idiopathic arthritis
    • Rosenberg AM, Cordeiro DM (2000) Relationship between sex and antibodies to high mobility group proteins 1 and 2 in juvenile idiopathic arthritis. J Rheumatol 27:2489-2493
    • (2000) J Rheumatol , vol.27 , pp. 2489-2493
    • Rosenberg, A.M.1    Cordeiro, D.M.2
  • 37
    • 0031887801 scopus 로고    scopus 로고
    • Prevalence and characterization of perinuclear anti-neutrophil cytoplasmic antibodies (P-ANCA) directed against HMG1 and HMG2 in ulcerative colitis (UC)
    • doi:10.1046/j.1365-2249.1998.00491.x
    • Sobajima J, Ozaki S, Uesugi H et al (1998) Prevalence and characterization of perinuclear anti-neutrophil cytoplasmic antibodies (P-ANCA) directed against HMG1 and HMG2 in ulcerative colitis (UC). Clin Exp Immunol 111:402-407. doi:10.1046/j.1365-2249.1998.00491.x
    • (1998) Clin Exp Immunol , vol.111 , pp. 402-407
    • Sobajima, J.1    Ozaki, S.2    Uesugi, H.3
  • 38
    • 0036137522 scopus 로고    scopus 로고
    • High prevalence of autoantibodies against the nuclear high mobility group (HMG) protein SSRP1 in sera from patients with systemic lupus erythematosus, but not other rheumatic diseases
    • Santoro P, De Andrea M, Migliaretti G et al (2002) High prevalence of autoantibodies against the nuclear high mobility group (HMG) protein SSRP1 in sera from patients with systemic lupus erythematosus, but not other rheumatic diseases. J Rheumatol 29:90-93
    • (2002) J Rheumatol , vol.29 , pp. 90-93
    • Santoro, P.1    De Andrea, M.2    Migliaretti, G.3
  • 39
    • 3142769084 scopus 로고    scopus 로고
    • Prevalence of autoantibodies against structure specific recognition protein 1 in systemic lupus erythematosus
    • doi:10.1191/ 0961203304lu1049oa
    • Fineschi S, Borghi MO, Riboldi P et al (2004) Prevalence of autoantibodies against structure specific recognition protein 1 in systemic lupus erythematosus. Lupus 13:463-468. doi:10.1191/ 0961203304lu1049oa
    • (2004) Lupus , vol.13 , pp. 463-468
    • Fineschi, S.1    Borghi, M.O.2    Riboldi, P.3
  • 40
    • 0031898556 scopus 로고    scopus 로고
    • Prevalence and characterization of novel pANCA, antibodies to the high mobility group non-histone chromosomal proteins HMG1 and HMG2, in systemic rheumatic diseases
    • Uesugi H, Ozaki S, Sobajima J et al (1998) Prevalence and characterization of novel pANCA, antibodies to the high mobility group non-histone chromosomal proteins HMG1 and HMG2, in systemic rheumatic diseases. J Rheumatol 25:703-709
    • (1998) J Rheumatol , vol.25 , pp. 703-709
    • Uesugi, H.1    Ozaki, S.2    Sobajima, J.3
  • 41
    • 34247236200 scopus 로고    scopus 로고
    • Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE
    • doi:10.1038/ni1457
    • Tian J, Avalos AM, Mao SY et al (2007) Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE. Nat Immunol 8:487-496. doi:10.1038/ni1457
    • (2007) Nat Immunol , vol.8 , pp. 487-496
    • Tian, J.1    Avalos, A.M.2    Mao, S.Y.3
  • 42
    • 9144241208 scopus 로고    scopus 로고
    • Reversing established sepsis with antagonists of endogenous high-mobility group box 1
    • doi:10.1073/pnas.2434651100
    • Yang H, Ochani M, Li J et al (2004) Reversing established sepsis with antagonists of endogenous high-mobility group box 1. Proc Natl Acad Sci USA 101:296-301. doi:10.1073/pnas.2434651100
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 296-301
    • Yang, H.1    Ochani, M.2    Li, J.3
  • 43
    • 0037125985 scopus 로고    scopus 로고
    • Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation
    • doi:10.1073/pnas.192222999
    • Ulloa L, Ochani M, Yang H et al (2002) Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation. Proc Natl Acad Sci USA 99:12351-12356. doi:10.1073/pnas.192222999
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 12351-12356
    • Ulloa, L.1    Ochani, M.2    Yang, H.3
  • 44
    • 77950682073 scopus 로고    scopus 로고
    • Antagonizing HMGB1 inhibits proteinuria in a murine model of lupus-like disease
    • Mao SY, Xu Y, Zhang J et al (2007) Antagonizing HMGB1 inhibits proteinuria in a murine model of lupus-like disease. J Immunol 178:131.24
    • (2007) J Immunol , vol.178 , Issue.131 , pp. 24
    • Mao, S.Y.1    Xu, Y.2    Zhang, J.3


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