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Volumn 45, Issue 5, 2010, Pages 608-614

Prediction of 6-thioguanine nucleotides levels in Japanese patients with inflammatory bowel diseases during long-term thiopurine administration

Author keywords

6 mercaptopurine; 6 thioguanine nucleotides; Azathioprine; Inflammatory bowel disease; Mean corpuscular volume

Indexed keywords

AZATHIOPRINE; HEMOGLOBIN; INFLIXIMAB; MERCAPTOPURINE; MESALAZINE; PREDNISOLONE; SALAZOSULFAPYRIDINE; THIOGUANOSINE;

EID: 77951673607     PISSN: 00365521     EISSN: 15027708     Source Type: Journal    
DOI: 10.3109/00365521003642559     Document Type: Article
Times cited : (10)

References (32)
  • 1
    • 0036278519 scopus 로고    scopus 로고
    • The efficacy of azathioprine for the treatment of inflammatory bowel disease: A 30 year review
    • DOI 10.1136/gut.50.4.485
    • Fraser AG, Orchard TR, Jewell DP. The efficacy of azathi-oprine for the treatment of inflammatory bowel disease: a 30 year review. Gut 2002;50:485-489 (Pubitemid 34638866)
    • (2002) Gut , vol.50 , Issue.4 , pp. 485-489
    • Fraser, A.G.1    Orchard, T.R.2    Jewell, D.P.3
  • 2
    • 0029923360 scopus 로고    scopus 로고
    • A review of immune modifier therapy for inflammatory bowel disease: Azathioprine, 6-mercaptopurine, cyclosporine, and methotrexate
    • Sandborn WJ. A review of immune modifier therapy for inflammatory bowel disease: azathioprine, 6-mercaptopurine, cyclosporine, and methotrexate. Am J Gastroenterol 1996;91:423-433 (Pubitemid 126733803)
    • (1996) American Journal of Gastroenterology , vol.91 , Issue.3 , pp. 423-433
    • Sandborn, W.J.1
  • 3
    • 29244457275 scopus 로고    scopus 로고
    • Randomised controlled trial of azathioprine and 5-aminosalicylic acid for treatment of steroid dependent ulcerative colitis
    • DOI 10.1136/gut.2005.068809
    • Ardizzone S, Maconi G, Russo A, Imbesi V, Colombo E, Bianchi Porro G. Randomised controlled trial of azathioprine and 5-aminosalicylic acid for treatment of steroid dependent ulcerative colitis. Gut 2006;55:47-53. (Pubitemid 41820634)
    • (2006) Gut , vol.55 , Issue.1 , pp. 47-53
    • Ardizzone, S.1    Maconi, G.2    Russo, A.3    Imbesi, V.4    Colombo, E.5    Porro, G.B.6
  • 6
    • 0027239758 scopus 로고
    • The pharmacology of azathioprine
    • Elion GB. The pharmacology of azathioprine. Ann NY Acad Sci 1993;685:400-407
    • (1993) Ann NY Acad Sci , vol.685 , pp. 400-407
    • Elion, G.B.1
  • 7
    • 0035037706 scopus 로고    scopus 로고
    • Utilisation of erythrocyte 6-thioguanine metabolite levels to optimise azathioprine therapy in patients with inflammatory bowel disease
    • DOI 10.1136/gut.48.5.642
    • Cuffari C, Hunt S, Bayless T. Utilisation of erythrocyte 6-thioguanine metabolite levels to optimise azathioprine therapy in patients with inflammatory bowel disease. Gut 2001;48:642-646 (Pubitemid 32378583)
    • (2001) Gut , vol.48 , Issue.5 , pp. 642-646
    • Cuffari, C.1    Hunt, S.2    Bayless, T.3
  • 8
    • 0034067784 scopus 로고    scopus 로고
    • Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease
    • Dubinsky MC, Lamothe S, Yang HY, Targan SR, Sinnett D, Théorêt Y, et al. Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease. Gastroenterology 2000;118:705-713 (Pubitemid 30171620)
    • (2000) Gastroenterology , vol.118 , Issue.4 , pp. 705-713
    • Dubinsky, M.C.1    Lamothe, S.2    Yang, H.Y.3    Targan, S.R.4    Sinnett, D.5    Theoret, Y.6    Seidman, E.G.7
  • 9
    • 33646011261 scopus 로고    scopus 로고
    • Association of 6-thioguanine nucleotide levels and inflammatory bowel disease activity: A meta-analysis
    • Osterman MT, Kundu R, Lichtenstein GR, Lewis JD. Association of 6-thioguanine nucleotide levels and inflammatory bowel disease activity: a meta-analysis. Gastroenterology 2006;130:1047-1053
    • (2006) Gastroenterology , vol.130 , pp. 1047-1053
    • Osterman, M.T.1    Kundu, R.2    Lichtenstein, G.R.3    Lewis, J.D.4
  • 10
    • 33644869450 scopus 로고    scopus 로고
    • American gastroenterological association institute technical review on corticosteroids, immunomodulators, and infliximab in inflammatory bowel disease
    • DOI 10.1053/j.gastro.2006.01.048, PII S0016508506000746
    • Lichtenstein GR, Abreu MT, Cohen R, Tremaine W; American Gastroenterological Association. American Gastro-enterological Association Institute technical reviewoncorticos-teroids, immunomodulators, and infliximab in inflammatory bowel disease. Gastroenterology 2006;130:940-987 (Pubitemid 43374543)
    • (2006) Gastroenterology , vol.130 , Issue.3 , pp. 940-987
    • Lichtenstein, G.R.1    Abreu, M.T.2    Cohen, R.3    Tremaine, W.4
  • 11
    • 0141521863 scopus 로고    scopus 로고
    • Low-dose azathioprine is effective and safe for maintenance of remission in patients with ulcerative colitis
    • DOI 10.1007/s00535-003-1139-2
    • Hibi T, Naganuma M, Kitahora T, Kinjyo F, Shimoyama T. Low-dose azathioprine is effective and safe for maintenance of remission in patients with ulcerative colitis. J Gastroenterol 2003;38:740-746 (Pubitemid 37161337)
    • (2003) Journal of Gastroenterology , vol.38 , Issue.8 , pp. 740-746
    • Hibi, T.1    Naganuma, M.2    Kitahora, T.3    Kinjyo, F.4    Shimoyama, T.5
  • 12
    • 49849105012 scopus 로고    scopus 로고
    • Monitoring 6-thioguanine nucleotide concentrations in Japanese patients with inflammatory bowel disease
    • Andoh A, Tsujikawa T, Ban H, Hashimoto T, Bamba S, Ogawa A, et al. Monitoring 6-thioguanine nucleotide concentrations in Japanese patients with inflammatory bowel disease. J Gastroenterol Hepatol 2008;23:1373-1377
    • (2008) J Gastroenterol Hepatol , vol.23 , pp. 1373-1377
    • Andoh, A.1    Tsujikawa, T.2    Ban, H.3    Hashimoto, T.4    Bamba, S.5    Ogawa, A.6
  • 13
    • 0034162598 scopus 로고    scopus 로고
    • Relationship between red cell mean corpuscular volume and 6-thioguanine nucleotides in patients treated with azathioprine
    • Decaux G, Prospert F, Horsmans Y, Desager JP. Relationship between red cell mean corpuscular volume and 6-thio-guanine nucleotides in patients treated with azathioprine. J Lab Clin Med 2000;135:256-262 (Pubitemid 30132348)
    • (2000) Journal of Laboratory and Clinical Medicine , vol.135 , Issue.3 , pp. 256-262
    • Decaux, G.1    Prospert, F.2    Horsmans, Y.3    Desager, J.P.4
  • 14
    • 2942515666 scopus 로고    scopus 로고
    • Red cell mean corpuscular volume (MCV) correlates with 6 thioguanine nucleotide (6TG) levels during azathioprine or 6-MP therapy for Crohn's disease (abstract)
    • Jobson B, Garza A, Sninsky A. Red cell mean corpuscular volume (MCV) correlates with 6 thioguanine nucleotide (6TG) levels during azathioprine or 6-MP therapy for Crohn's disease (abstract). Gastroenterology 2001; 120(Suppl 1):A4.
    • (2001) Gastroenterology , vol.120 , Issue.SUPPL. 1
    • Jobson, B.1    Garza, A.2    Sninsky, A.3
  • 15
  • 16
    • 0142026071 scopus 로고    scopus 로고
    • Erythrocyte mean corpuscular volume as a surrogate marker for 6-thioguanine nucleotide concentration monitoring in patients with inflammatory bowel disease treated with azathioprine or 6-mercaptopurine
    • Thomas CW Jr, Lowry PW, Franklin CL, Weaver AL, Myhre GM, Mays DC, et al. Erythrocyte mean corpuscular volume as a surrogate marker for 6-thioguanine nucleotide concentration monitoring in patients with inflammatory bowel disease treated with azathioprine or 6-mercaptopurine. Inflamm Bowel Dis 2003;9:237-245
    • (2003) Inflamm Bowel Dis , vol.9 , pp. 237-245
    • Thomas Jr, C.W.1    Lowry, P.W.2    Franklin, C.L.3    Weaver, A.L.4    Myhre, G.M.5    Mays, D.C.6
  • 20
    • 0035037703 scopus 로고    scopus 로고
    • Rational dosing of azathioprine and 6-mer-captopurine
    • Sandborn WJ. Rational dosing of azathioprine and 6-mer-captopurine. Gut 2001;48:591-592
    • (2001) Gut , vol.48 , pp. 591-592
    • Sandborn, W.J.1
  • 21
    • 0037253045 scopus 로고    scopus 로고
    • Systemic review: The pharma-cokinetic profiles of oral mesalazine formulations and mesa-lazine pro-drugs used in the management of ulcerative colitis
    • Sandborn WJ, Hanauer SB. Systemic review: the pharma-cokinetic profiles of oral mesalazine formulations and mesa-lazine pro-drugs used in the management of ulcerative colitis. Aliment Pharmacol Ther 2003;17:29-42.
    • (2003) Aliment Pharmacol Ther , vol.17 , pp. 29-42
    • Sandborn, W.J.1    Hanauer, S.B.2
  • 22
    • 0026465403 scopus 로고
    • High-performance liquid chro-matographic assay of the methyl and nucleotide metabolites of 6-mercaptopurine: Quantitation of red blood cell 6-thioguanine nucleotide, 6-thioinosinic acid and 6-methylmercaptopurine metabolites in a single sample
    • Lennard L, Singleton HJ. High-performance liquid chro-matographic assay of the methyl and nucleotide metabolites of 6-mercaptopurine: quantitation of red blood cell 6-thioguanine nucleotide, 6-thioinosinic acid and 6-methylmercaptopurine metabolites in a single sample. J Chromatogr 1992;583:83-90.
    • (1992) J Chromatogr , vol.583 , pp. 83-90
    • Lennard, L.1    Singleton, H.J.2
  • 23
    • 33645311528 scopus 로고    scopus 로고
    • The inconsistency of "optimal" cutpoints obtained using two criteria based on the receiver operating characteristic curve
    • Perkins NJ, Schisterman EF. The inconsistency of "optimal" cutpoints obtained using two criteria based on the receiver operating characteristic curve. Am J Epidemiol 2006;163: 670-675
    • (2006) Am J Epidemiol , vol.163 , pp. 670-675
    • Perkins, N.J.1    Schisterman, E.F.2
  • 24
    • 0016314753 scopus 로고
    • Observations on the incidence and cause of macrocytosis in patients on azathioprine therapy following renal transplantation
    • Wickramasinghe SN, Dodsworth H, Rault RM, Hulme B. Observations on the incidence and cause of macrocytosis in patients on azathioprine therapy following renal transplantation. Transplantation 1974;18:443-446
    • (1974) Transplantation , vol.18 , pp. 443-446
    • Wickramasinghe, S.N.1    Dodsworth, H.2    Rault, R.M.3    Hulme, B.4
  • 25
    • 0031680256 scopus 로고    scopus 로고
    • Safety of azathioprine and 6-mercaptopurine in pediatric patients with inflammatory bowel disease
    • DOI 10.1016/S0016-5085(98)70251-3
    • Kirschner BS. Safety of azathioprine and 6-mercaptopurine in pediatric patients with inflammatory bowel disease. Gastroenterology 1998;115:813-821 (Pubitemid 28452927)
    • (1998) Gastroenterology , vol.115 , Issue.4 , pp. 813-821
    • Kirschner, B.S.1
  • 26
    • 0016592444 scopus 로고
    • Erythroid toxicity of azathioprine. Macrocytosis and selective marrow hypoplasis
    • McGrath BP, Ibels LS, Raik E, Hargrave MJ. Erythroid toxicity of azathioprine. Macrocytosis and selective marrow hypoplasis. Q J Med 1975;44:57-63.
    • (1975) Q J Med , vol.44 , pp. 57-63
    • McGrath, B.P.1    Ibels, L.S.2    Raik, E.3    Hargrave, M.J.4
  • 28
    • 33845415085 scopus 로고    scopus 로고
    • Thiopurine methyltransferase (TPMT) activity and adverse effects of azathioprine in inflammatory bowel disease: Long-term follow-up study of 394 patients
    • DOI 10.1111/j.1572-0241.2006.00843.x
    • Gisbert JP, Niño P, Rodrigo L, Cara C, Guijarro LG. Thio-purine methyltransferase (TPMT) activity and adverse effects of azathioprine in inflammatory bowel disease: long-term follow-up study of 394 patients. Am J Gastroen-terol 2006;101:2769-2776 (Pubitemid 44902649)
    • (2006) American Journal of Gastroenterology , vol.101 , Issue.12 , pp. 2769-2776
    • Gisbert, J.P.1    Nino, P.2    Rodrigo, L.3    Cara, C.4    Guijarro, L.G.5
  • 29
    • 15944394455 scopus 로고    scopus 로고
    • Thiopurine methyltransferase (TPMT) heterozygosity and enzyme activity as predictive tests for the development of azathioprine-related adverse events
    • DOI 10.1016/j.jns.2005.01.003
    • Heckmann JM, Lambson EM, Little F, Owen EP. Thiopur-ine methyltransferase (TPMT) heterozygosity and enzyme activity as predictive tests for the development of azathioprine-related adverse events. J Neurol Sci 2005;231:71-80. (Pubitemid 40432029)
    • (2005) Journal of the Neurological Sciences , vol.231 , Issue.1-2 , pp. 71-80
    • Heckmann, J.M.1    Lambson, E.M.T.2    Little, F.3    Owen, E.P.4
  • 30
    • 68749111832 scopus 로고    scopus 로고
    • Adverse reactions to azathioprine cannot be predicted by thiopurine S-methyltransferase genotype in Japanese patients with inflammatory bowel disease
    • Takatsu N, Matsui T, Murakami Y, Ishihara H, Hisabe T, Nagahama T, et al. Adverse reactions to azathioprine cannot be predicted by thiopurine S-methyltransferase genotype in Japanese patients with inflammatory bowel disease. J Gastroenterol Hepatol 2009;24:1258-1264
    • (2009) J Gastroenterol Hepatol , vol.24 , pp. 1258-1264
    • Takatsu, N.1    Matsui, T.2    Murakami, Y.3    Ishihara, H.4    Hisabe, T.5    Nagahama, T.6
  • 31
    • 0034771188 scopus 로고    scopus 로고
    • Measurement of thiopur-ine methyltransferase activity and azathioprine metabolites in patients with inflammatory bowel disease
    • Lowry PW, Franklin CL, Weaver AL, Pike MG, Mays DC, Tremaine WJ, et al. Measurement of thiopur-ine methyltransferase activity and azathioprine metabolites in patients with inflammatory bowel disease. Gut 2001;49: 665-670
    • (2001) Gut , vol.49 , pp. 665-670
    • Lowry, P.W.1    Franklin, C.L.2    Weaver, A.L.3    Pike, M.G.4    Mays, D.C.5    Tremaine, W.J.6
  • 32
    • 4544294487 scopus 로고    scopus 로고
    • The utility of 6-thioguanine metabolite levels in managing patients with inflammatory bowel disease
    • DOI 10.1111/j.1572-0241.2004.30415.x
    • Goldenberg BA, Rawsthorne P, Bernstein CN. The utility of 6-thioguanine metabolite levels in managing patients with inflammatory bowel disease. Am J Gastroenterol 2004; 99:1744-1748 (Pubitemid 39237503)
    • (2004) American Journal of Gastroenterology , vol.99 , Issue.9 , pp. 1744-1748
    • Goldenberg, B.A.1    Rawsthorne, P.2    Bernstein, C.N.3


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