메뉴 건너뛰기




Volumn 23, Issue 9, 2008, Pages 1373-1377

Monitoring 6-thioguanine nucleotide concentrations in Japanese patients with inflammatory bowel disease

Author keywords

6 mercaptopurine; Azathioprine; Thiopurine S methyl transferase

Indexed keywords

AZATHIOPRINE; MERCAPTOPURINE; MESALAZINE; THIOPURINE METHYLTRANSFERASE; TIOGUANINE;

EID: 49849105012     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2008.05419.x     Document Type: Article
Times cited : (30)

References (27)
  • 1
    • 0025330168 scopus 로고
    • The therapeutic efficacy of 6-mercaptopurine in refractory ulcerative colitis
    • Adler DJ, Korelitz BI. The therapeutic efficacy of 6-mercaptopurine in refractory ulcerative colitis. Am. J. Gastroenterol. 1990 85 : 717 22.
    • (1990) Am. J. Gastroenterol. , vol.85 , pp. 717-722
    • Adler, D.J.1    Korelitz, B.I.2
  • 3
    • 33644500497 scopus 로고    scopus 로고
    • Novel pathophysiological concepts of inflammatory bowel disease
    • Hibi T, Ogata H. Novel pathophysiological concepts of inflammatory bowel disease. J. Gastroenterol. 2006 41 : 10 16.
    • (2006) J. Gastroenterol. , vol.41 , pp. 10-16
    • Hibi, T.1    Ogata, H.2
  • 4
  • 5
    • 33745513801 scopus 로고    scopus 로고
    • Pharmacokinetics of 6-thioguanine in patients with inflammatory bowel disease
    • Derijks LJ, Gilissen LP, Engels LG et al. Pharmacokinetics of 6-thioguanine in patients with inflammatory bowel disease. Ther. Drug Monit. 2006 28 : 45 50.
    • (2006) Ther. Drug Monit. , vol.28 , pp. 45-50
    • Derijks, L.J.1    Gilissen, L.P.2    Engels, L.G.3
  • 6
    • 37249032702 scopus 로고    scopus 로고
    • IMPDH activity in thiopurine-treated patients with inflammatory bowel disease - Relation to TPMT activity and metabolite concentrations
    • Haglund S, Taipalensuu J, Peterson C, Almer S. IMPDH activity in thiopurine-treated patients with inflammatory bowel disease - relation to TPMT activity and metabolite concentrations. Br. J. Clin. Pharmacol. 2007 65 : 69 77.
    • (2007) Br. J. Clin. Pharmacol. , vol.65 , pp. 69-77
    • Haglund, S.1    Taipalensuu, J.2    Peterson, C.3    Almer, S.4
  • 7
    • 33646011261 scopus 로고    scopus 로고
    • Association of 6-thioguanine nucleotide levels and inflammatory bowel disease activity: A meta-analysis
    • Osterman MT, Kundu R, Lichtenstein GR, Lewis JD. Association of 6-thioguanine nucleotide levels and inflammatory bowel disease activity: a meta-analysis. Gastroenterology 2006 130 : 1047 53.
    • (2006) Gastroenterology , vol.130 , pp. 1047-1053
    • Osterman, M.T.1    Kundu, R.2    Lichtenstein, G.R.3    Lewis, J.D.4
  • 8
    • 0242464926 scopus 로고    scopus 로고
    • CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes
    • Tiede I, Fritz G, Strand S et al. CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes. J. Clin. Invest. 2003 111 : 1133 45.
    • (2003) J. Clin. Invest. , vol.111 , pp. 1133-1145
    • Tiede, I.1    Fritz, G.2    Strand, S.3
  • 9
    • 0034093057 scopus 로고    scopus 로고
    • Genotypic analysis of thiopurine S-methyltransferase in patients with Crohn's disease and severe myelosuppression during azathioprine therapy
    • Colombel JF, Ferrari N, Debuysere H et al. Genotypic analysis of thiopurine S-methyltransferase in patients with Crohn's disease and severe myelosuppression during azathioprine therapy. Gastroenterology 2000 118 : 1025 30.
    • (2000) Gastroenterology , vol.118 , pp. 1025-1030
    • Colombel, J.F.1    Ferrari, N.2    Debuysere, H.3
  • 10
    • 0042830383 scopus 로고    scopus 로고
    • Thiopurine S-methyltransferase (TPMT) genotype does not predict adverse drug reactions to thiopurine drugs in patients with inflammatory bowel disease
    • Gearry RB, Barclay ML, Burt MJ et al. Thiopurine S-methyltransferase (TPMT) genotype does not predict adverse drug reactions to thiopurine drugs in patients with inflammatory bowel disease. Aliment. Pharmacol. Ther. 2003 18 : 395 400.
    • (2003) Aliment. Pharmacol. Ther. , vol.18 , pp. 395-400
    • Gearry, R.B.1    Barclay, M.L.2    Burt, M.J.3
  • 11
    • 0035037703 scopus 로고    scopus 로고
    • Rational dosing of azathioprine and 6-mercaptopurine
    • Sandborn WJ. Rational dosing of azathioprine and 6-mercaptopurine. Gut 2001 48 : 591 2.
    • (2001) Gut , vol.48 , pp. 591-592
    • Sandborn, W.J.1
  • 12
    • 0141521863 scopus 로고    scopus 로고
    • Low-dose azathioprine is effective and safe for maintenance of remission in patients with ulcerative colitis
    • Hibi T, Naganuma M, Kitahora T, Kinjyo F, Shimoyama T. Low-dose azathioprine is effective and safe for maintenance of remission in patients with ulcerative colitis. J. Gastroenterol. 2003 38 : 740 6.
    • (2003) J. Gastroenterol. , vol.38 , pp. 740-746
    • Hibi, T.1    Naganuma, M.2    Kitahora, T.3    Kinjyo, F.4    Shimoyama, T.5
  • 13
    • 0024587677 scopus 로고
    • Coated mesalazine (5-aminosalicylic acid) versus sulphasalazine in the treatment of active ulcerative colitis: A randomised trial
    • Rachmilewitz D. Coated mesalazine (5-aminosalicylic acid) versus sulphasalazine in the treatment of active ulcerative colitis: a randomised trial. BMJ 1989 298 : 82 6.
    • (1989) BMJ , vol.298 , pp. 82-86
    • Rachmilewitz, D.1
  • 14
    • 0017227303 scopus 로고
    • Development of a Crohn's disease activity index. National Cooperative Crohn's Disease Study
    • Jr.
    • Best WR, Becktel JM, Singleton JW, Kern F Jr. Development of a Crohn's disease activity index. National Cooperative Crohn's Disease Study. Gastroenterology 1976 70 : 439 44.
    • (1976) Gastroenterology , vol.70 , pp. 439-444
    • Best, W.R.1    Becktel, J.M.2    Singleton, J.W.3    Kern, F.4
  • 16
    • 0030934850 scopus 로고    scopus 로고
    • Molecular diagnosis of thiopurine S-methyltransferase deficiency: Genetic basis for azathioprine and mercaptopurine intolerance
    • Yates CR, Krynetski EY, Loennechen T et al. Molecular diagnosis of thiopurine S-methyltransferase deficiency: genetic basis for azathioprine and mercaptopurine intolerance. Ann. Intern. Med. 1997 126 : 608 14.
    • (1997) Ann. Intern. Med. , vol.126 , pp. 608-614
    • Yates, C.R.1    Krynetski, E.Y.2    Loennechen, T.3
  • 17
    • 0037256180 scopus 로고    scopus 로고
    • Introduction and overview: Recent advances in the immunotherapy of inflammatory bowel disease
    • Hibi T, Inoue N, Ogata H, Naganuma M. Introduction and overview: recent advances in the immunotherapy of inflammatory bowel disease. J. Gastroenterol. 2003 38 (Suppl. 15 36 42.
    • (2003) J. Gastroenterol. , vol.3815 , pp. 36-42
    • Hibi, T.1    Inoue, N.2    Ogata, H.3    Naganuma, M.4
  • 18
    • 4344587708 scopus 로고    scopus 로고
    • Therapeutic drug monitoring in patients with inflammatory bowel disease and established azathioprine therapy
    • Gilissen LP, Derijks LJ, Bos LP, Bus PJ, Hooymans PM, Engels LG. Therapeutic drug monitoring in patients with inflammatory bowel disease and established azathioprine therapy. Clin. Drug Invest. 2004 24 : 479 86.
    • (2004) Clin. Drug Invest. , vol.24 , pp. 479-486
    • Gilissen, L.P.1    Derijks, L.J.2    Bos, L.P.3    Bus, P.J.4    Hooymans, P.M.5    Engels, L.G.6
  • 19
    • 4544294487 scopus 로고    scopus 로고
    • The utility of 6-thioguanine metabolite levels in managing patients with inflammatory bowel disease
    • Goldenberg BA, Rawsthorne P, Bernstein CN. The utility of 6-thioguanine metabolite levels in managing patients with inflammatory bowel disease. Am. J. Gastroenterol. 2004 99 : 1744 8.
    • (2004) Am. J. Gastroenterol. , vol.99 , pp. 1744-1748
    • Goldenberg, B.A.1    Rawsthorne, P.2    Bernstein, C.N.3
  • 20
    • 0035037706 scopus 로고    scopus 로고
    • Utilisation of erythrocyte 6-thioguanine metabolite levels to optimise azathioprine therapy in patients with inflammatory bowel disease
    • Cuffari C, Hunt S, Bayless T. Utilisation of erythrocyte 6-thioguanine metabolite levels to optimise azathioprine therapy in patients with inflammatory bowel disease. Gut 2001 48 : 642 6.
    • (2001) Gut , vol.48 , pp. 642-646
    • Cuffari, C.1    Hunt, S.2    Bayless, T.3
  • 21
    • 3242732900 scopus 로고    scopus 로고
    • Clinical significance of azathioprine active metabolite concentrations in inflammatory bowel disease
    • Wright S, Sanders DS, Lobo AJ, Lennard L. Clinical significance of azathioprine active metabolite concentrations in inflammatory bowel disease. Gut 2004 53 : 1123 8.
    • (2004) Gut , vol.53 , pp. 1123-1128
    • Wright, S.1    Sanders, D.S.2    Lobo, A.J.3    Lennard, L.4
  • 22
    • 0034067784 scopus 로고    scopus 로고
    • Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease
    • Dubinsky MC, Lamothe S, Yang HY et al. Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease. Gastroenterology 2000 118 : 705 13.
    • (2000) Gastroenterology , vol.118 , pp. 705-713
    • Dubinsky, M.C.1    Lamothe, S.2    Yang, H.Y.3
  • 23
    • 0035186469 scopus 로고    scopus 로고
    • 6-mercaptopurine metabolite levels in children with inflammatory bowel disease
    • Gupta P, Gokhale R, Kirschner BS. 6-mercaptopurine metabolite levels in children with inflammatory bowel disease. J. Pediatr. Gastroenterol. Nutr. 2001 33 : 450 4.
    • (2001) J. Pediatr. Gastroenterol. Nutr. , vol.33 , pp. 450-454
    • Gupta, P.1    Gokhale, R.2    Kirschner, B.S.3
  • 24
    • 27744461917 scopus 로고    scopus 로고
    • Azathioprine and 6-mercaptopurine pharmacogenetics and metabolite monitoring in inflammatory bowel disease
    • Gearry RB, Barclay ML. Azathioprine and 6-mercaptopurine pharmacogenetics and metabolite monitoring in inflammatory bowel disease. J. Gastroenterol. Hepatol. 2005 20 : 1149 57.
    • (2005) J. Gastroenterol. Hepatol. , vol.20 , pp. 1149-1157
    • Gearry, R.B.1    Barclay, M.L.2
  • 25
    • 2542596944 scopus 로고    scopus 로고
    • Frequency distribution of thiopurine S-methyltransferase activity in red blood cells of a healthy Japanese population
    • Kubota T, Nishida A, Takeuchi K et al. Frequency distribution of thiopurine S-methyltransferase activity in red blood cells of a healthy Japanese population. Ther. Drug Monit. 2004 26 : 319 21.
    • (2004) Ther. Drug Monit. , vol.26 , pp. 319-321
    • Kubota, T.1    Nishida, A.2    Takeuchi, K.3
  • 27
    • 34247094129 scopus 로고    scopus 로고
    • Three novel single nucleotide polymorphisms of the human thiopurine S-methyltransferase gene in Japanese individuals
    • Sasaki T, Goto E, Konno Y, Hiratsuka M, Mizugaki M. Three novel single nucleotide polymorphisms of the human thiopurine S-methyltransferase gene in Japanese individuals. Drug Metab. Pharmacokinet. 2006 21 : 332 6.
    • (2006) Drug Metab. Pharmacokinet. , vol.21 , pp. 332-336
    • Sasaki, T.1    Goto, E.2    Konno, Y.3    Hiratsuka, M.4    Mizugaki, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.