메뉴 건너뛰기




Volumn 25, Issue 5, 2010, Pages 1435-1443

N-acetylcysteine attenuates glycerol-induced acute kidney injury by regulating MAPKs and Bcl-2 family proteins

Author keywords

Acute kidney injury; Bcl 2 family proteins; MAPKs; N acetylcysteine; Rhabdomyolysis

Indexed keywords

ACETYLCYSTEINE; CREATININE; GLUTATHIONE; GLYCEROL; HEME OXYGENASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; STRESS ACTIVATED PROTEIN KINASE;

EID: 77951669082     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfp659     Document Type: Article
Times cited : (94)

References (52)
  • 2
    • 0023710476 scopus 로고
    • Factors predictive of acute renal failure in rhabdomyoly-sis
    • Ward MM. Factors predictive of acute renal failure in rhabdomyoly-sis. Arch Intern Med 1988; 148: 1553-1557
    • (1988) Arch Intern Med , vol.148 , pp. 1553-1557
    • Ward, M.M.1
  • 3
    • 12444254008 scopus 로고    scopus 로고
    • Acute renal failure and rhabdomyolysis
    • Polderman KH. Acute renal failure and rhabdomyolysis. Int J Artif Organs 2004; 27: 1030-1033
    • (2004) Int J Artif Organs , vol.27 , pp. 1030-1033
    • Polderman, K.H.1
  • 4
    • 15844385432 scopus 로고    scopus 로고
    • Bench-to-bedside review: Rhabdomyolysis - An overview for clinicians
    • DOI 10.1186/cc2978
    • Huerta-Alardín AL, Varon J, Marik PE. Bench-to-bedside review: rhabdomyolysis-an overview for clinicians. Crit Care 2005; 9: 158-169 (Pubitemid 40425441)
    • (2005) Critical Care , vol.9 , Issue.2 , pp. 158-169
    • Huerta-Alardin, A.L.1    Varon, J.2    Marik, P.E.3
  • 5
    • 0026755754 scopus 로고
    • Induction of heme oxyge-nase is a rapid, protective response in rhabdomyolysis in the rat
    • Nath KA, Balla G, Vercellotti GM, et al. Induction of heme oxyge-nase is a rapid, protective response in rhabdomyolysis in the rat. J Clin Invest 1992; 90: 267-270
    • (1992) J Clin Invest , vol.90 , pp. 267-270
    • Nath, K.A.1    Balla, G.2    Vercellotti, G.M.3
  • 6
    • 0023755521 scopus 로고
    • Hemoglobin-and myoglobin-induced acute renal failure in rats: Role of iron in nephrotoxicity
    • Paller MS. Hemoglobin-and myoglobin-induced acute renal failure in rats: role of iron in nephrotoxicity. Am J Physiol 1988; 255: 539-544
    • (1988) Am J Physiol , vol.255 , pp. 539-544
    • Paller, M.S.1
  • 7
    • 0042829085 scopus 로고    scopus 로고
    • Catechin, a natural antioxidant protects against rhabdomyolysis-induced myoglobinuric acute renal failure
    • DOI 10.1016/S1043-6618(03)00207-X
    • Chander V, Singh D, Chopra K. Catechin, a natural antioxidant protects against rhabdomyolysis-induced myoglobinuric acute renal failure. Pharmacol Res 2003; 48: 503-509 (Pubitemid 37101209)
    • (2003) Pharmacological Research , vol.48 , Issue.5 , pp. 503-509
    • Chander, V.1    Singh, D.2    Chopra, K.3
  • 9
    • 10844290692 scopus 로고    scopus 로고
    • Reversal of experimental myoglobinuric acute renal failure in rats by quercetin, a bioflavonoid
    • DOI 10.1159/000081074
    • Singh D, Chopra K. Reversal of experimental myoglobinuric acute renal failure in rats by quercetin, a bioflavonoid. Pharmacology 2005; 73: 49-56 (Pubitemid 39664221)
    • (2005) Pharmacology , vol.73 , Issue.1 , pp. 49-56
    • Chander, V.1    Singh, D.2    Chopra, K.3
  • 11
    • 49649120171 scopus 로고    scopus 로고
    • Experimental myoglobinuric acute renal failure: The effect of vitamin C
    • Ustundag S, Yalcin O, Sen S, et al. Experimental myoglobinuric acute renal failure: the effect of vitamin C. Ren Fail 2008; 30: 727-735
    • (2008) Ren Fail , vol.30 , pp. 727-735
    • Ustundag, S.1    Yalcin, O.2    Sen, S.3
  • 13
    • 46849115807 scopus 로고    scopus 로고
    • The molecular mechanisms of the attenuation of cisplatin-induced acute renal failure by N-acetylcysteine in rats
    • DOI 10.1093/ndt/gfn090
    • Luo J, Tsuji T, Yasuda H, et al. The molecular mechanisms of the attenuation of cisplatin-induced acute renal failure by N-acetylcys-teine in rats. Nephrol Dial Transplant 2008; 23: 2198-2205 (Pubitemid 351957613)
    • (2008) Nephrology Dialysis Transplantation , vol.23 , Issue.7 , pp. 2198-2205
    • Luo, J.1    Tsuji, T.2    Yasuda, H.3    Sun, Y.4    Fujigaki, Y.5    Hishida, A.6
  • 14
    • 0242585010 scopus 로고    scopus 로고
    • Protective effect of aqueous garlic extract against oxidative organ damage in a rat model of thermal injury
    • DOI 10.1016/S0024-3205(03)00236-4
    • Sehirli AO, Sener G, Satiroglu H, et al. Protective effect of N-acetyl-cysteine on renal ischemia/reperfusion injury in the rat. J Nephrol 2003; 16: 75-80 (Pubitemid 36515137)
    • (2003) Life Sciences , vol.73 , Issue.1 , pp. 81-91
    • Sener, G.1    Satiroglu, H.2    Sehirli, A.O.3    Kacmaz, A.4
  • 15
    • 33646181085 scopus 로고    scopus 로고
    • N-acetylcysteine attenuates kidney injury in rats subjected to renal ischaemia-reperfusion
    • Nitescu N, Ricksten SE, Marcussen N, et al. N-acetylcysteine attenuates kidney injury in rats subjected to renal ischaemia-reperfusion. Nephrol Dial Transplant 2006; 21: 1240-1247
    • (2006) Nephrol Dial Transplant , vol.21 , pp. 1240-1247
    • Nitescu, N.1    Ricksten, S.E.2    Marcussen, N.3
  • 18
    • 0036440185 scopus 로고    scopus 로고
    • Effects of N-acetylcysteine on myoglobinuric-acute renal failure in rats
    • DOI 10.1081/JDI-120015676
    • Fernández-Fúnez A, Polo FJ, Broseta L, et al. Effects of N-acetylcys-teine on myoglobinuric-acute renal failure in rats. Ren Fail 2002; 24: 725-733 (Pubitemid 35404065)
    • (2002) Renal Failure , vol.24 , Issue.6 , pp. 725-733
    • Fernandez-Funez, A.1    Polo, F.J.2    Broseta, L.3    Valer, J.4    Zafrilla, L.5
  • 19
    • 0032743421 scopus 로고
    • Inhibition of apoptosis induced by ischemia-reperfusion prevents inflammation
    • Daemen MA, van't Veer C, Denecker G, et al. Inhibition of apoptosis induced by ischemia-reperfusion prevents inflammation. J Clin Invest 1991; 104: 541-549
    • (1991) J Clin Invest , vol.104 , pp. 541-549
    • Daemen, M.A.1    Van'T Veer, C.2    Denecker, G.3
  • 20
    • 0035180186 scopus 로고    scopus 로고
    • Guanosine supplementation reduces apoptosis and protects renal function in the setting of ischemic injury
    • DOI 10.1172/JCI200113018
    • Kelly KJ, Plotkin Z, Dagher PC. Guanosine supplementation reduces apoptosis and protects renal function in the setting of ischemic injury. J Clin Invest 2001; 108: 1291-1298 (Pubitemid 33107756)
    • (2001) Journal of Clinical Investigation , vol.108 , Issue.9 , pp. 1291-1298
    • Kelly, K.J.1    Plotkin, Z.2    Dagher, P.C.3
  • 22
    • 0028880006 scopus 로고
    • Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
    • Xia Z, Dickens M, Raingeaud J, et al. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 1995; 270: 1326-1331
    • (1995) Science , vol.270 , pp. 1326-1331
    • Xia, Z.1    Dickens, M.2    Raingeaud, J.3
  • 23
    • 0034644522 scopus 로고    scopus 로고
    • Signal transduction by the JNK group of MAP kinases
    • Davis RJ. Signal transduction by the JNK group of MAP kinases. Cell 2000; 103: 239-252
    • (2000) Cell , vol.103 , pp. 239-252
    • Davis, R.J.1
  • 25
    • 0035083846 scopus 로고    scopus 로고
    • Role of apoptosis of renal tubular cells in acute renal failure: Therapeutic implications
    • DOI 10.1023/A:1009680229931
    • Rana A, Sathyanarayana P, Lieberthal W. Role of apoptosis of renal tubular cells in acute renal failure: therapeutic implications. Apoptosis 2001; 6: 83-102 (Pubitemid 32233957)
    • (2001) Apoptosis , vol.6 , Issue.1-2 , pp. 83-102
    • Rana, A.1    Sathyanarayana, P.2    Lieberthal, W.3
  • 29
    • 17444433735 scopus 로고    scopus 로고
    • The repetitive activation of extracellular signal-regulated kinase is required for renal regeneration in rat
    • DOI 10.1016/S0024-3205(98)00215-X, PII S002432059800215X
    • Yano T, Yano Y, Yuasa M, et al. The repetitive activation of extracellular signal-regulated kinase is required for renal regeneration in rat. Life Sci 1998; 62: 2341-2347 (Pubitemid 28273163)
    • (1998) Life Sciences , vol.62 , Issue.25 , pp. 2341-2347
    • Yano, T.1    Yano, Y.2    Yuasa, M.3    Horikawa, S.4    Ozasa, H.5    Okada, S.6    Otani, S.7    Hagiwara, K.8
  • 30
    • 34848890388 scopus 로고    scopus 로고
    • Lipoic acid and N-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts
    • Mini-Forum "Mitochondria in Alzheimer Disease"
    • Moreira PI, Harris PL, Zhu X, et al. Lipoic acid and N-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts. J Alzheimers Dis 2007; 12: 195-206 (Pubitemid 47509369)
    • (2007) Journal of Alzheimer's Disease , vol.12 , Issue.2 , pp. 195-206
    • Moreira, P.I.1    Harris, P.L.R.2    Zhu, X.3    Santos, M.S.4    Oliveira, C.R.5    Smith, M.A.6    Perry, G.7
  • 31
    • 33750484015 scopus 로고    scopus 로고
    • Antioxidant and anti-inflammatory efficacy of NAC in the treatment of COPD: Discordant in vitro and in vivo dose-effects: A review
    • Sadowska AM, Manuel-Y-Keenoy B, De Backer WA. Antioxidant and anti-inflammatory efficacy of NAC in the treatment of COPD: discordant in vitro and in vivo dose-effects: a review. Pulm Pharmacol Ther 2007; 20: 9-22
    • (2007) Pulm Pharmacol Ther , vol.20 , pp. 9-22
    • Sadowska, A.M.1    Manuel-Y-Keenoy, B.2    De Backer, W.A.3
  • 33
    • 0033847184 scopus 로고    scopus 로고
    • The indispensability of heme oxygenase-1 in protecting against acute heme protein-induced toxic-ity in vivo
    • Nath KA, Haggard JJ, Croatt AJ, et al. The indispensability of heme oxygenase-1 in protecting against acute heme protein-induced toxic-ity in vivo. Am J Pathol 2000; 156: 1527-1535
    • (2000) Am J Pathol , vol.156 , pp. 1527-1535
    • Nath, K.A.1    Haggard, J.J.2    Croatt, A.J.3
  • 35
    • 43749101881 scopus 로고    scopus 로고
    • Effect of N-acetylcys-teine route of administration on chemoprotection against cisplatin-in-duced toxicity in rat models
    • Dickey DT, Muldoon LL, Doolittle ND, et al. Effect of N-acetylcys-teine route of administration on chemoprotection against cisplatin-in-duced toxicity in rat models. Cancer Chemother Pharmacol 2008; 62: 235-241
    • (2008) Cancer Chemother Pharmacol , vol.62 , pp. 235-241
    • Dickey, D.T.1    Muldoon, L.L.2    Doolittle, N.D.3
  • 36
    • 0028864695 scopus 로고
    • N-acetylcysteine-promoted survival of PC12 cells is glutathione- independent but transcription-dependent
    • Yan CY, Ferrari G, Greene LA. N-acetylcysteine-promoted survival of PC12 cells is glutathione-independent but transcription-dependent. J Biol Chem 1995; 270: 26827-26832
    • (1995) J Biol Chem , vol.270 , pp. 26827-26832
    • Yan, C.Y.1    Ferrari, G.2    Greene, L.A.3
  • 37
    • 0344878874 scopus 로고    scopus 로고
    • Prevention of PC12 cell death by N-acetylcysteine requires activation of the Ras pathway
    • Yan CY, Greene LA. Prevention of PC12 cell death by N-acetylcysteine requires activation of the Ras pathway. J Neurosci 1998; 18: 4042-4049
    • (1998) J Neurosci , vol.18 , pp. 4042-4049
    • Yan, C.Y.1    Greene, L.A.2
  • 38
    • 0028916027 scopus 로고
    • N-acetylcysteine (D-and L-Stereo-isomers) prevents apoptotic cell death of neuronal cells
    • Ferrari G, Yan CYI, Greene LA. N-acetylcysteine (D-and L-Stereo-isomers) prevents apoptotic cell death of neuronal cells. J Neurosci 1995; 15: 2857-2865
    • (1995) J Neurosci , vol.15 , pp. 2857-2865
    • Ferrari, G.1    Yan, C.Y.I.2    Greene, L.A.3
  • 39
    • 0030945822 scopus 로고    scopus 로고
    • Renal stress response and acute renal failure
    • Safirstein R. Renal stress response and acute renal failure. Adv Renal Replace Ther 1997; 4: 38-42 (Pubitemid 27198004)
    • (1997) Advances in Renal Replacement Therapy , vol.4 , Issue.2 SUPPL. 1 , pp. 38-42
    • Safirstein, R.1
  • 41
    • 0037044748 scopus 로고    scopus 로고
    • + transport, and cisplatin-induced apoptosis in renal cells
    • DOI 10.1074/jbc.M206373200
    • Nowak G. Protein kinase C-alpha and ERK1/2 mediate mitochondrial dysfunction, decreases in active Na transport, and cisplatin-induced apoptosis in renal cells. J Biol Chem 2002; 277: 43377-43388 (Pubitemid 35285726)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.45 , pp. 43377-43388
    • Nowak, G.1
  • 43
    • 0037174934 scopus 로고    scopus 로고
    • JNK phosphorylation and activation of bad couples the stress-activated signaling pathway to the cell death machinery
    • DOI 10.1074/jbc.M206113200
    • Donovan N, Becker EB, Konishi Y, et al. JNK phosphorylation and activation of BAD couples the stress-activated signaling pathway to the cell death machinery. J Biol Chem 2002; 277: 40944-40949 (Pubitemid 35215682)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.43 , pp. 40944-40949
    • Donovan, N.1    Becker, E.B.E.2    Konishi, Y.3    Bonni, A.4
  • 45
    • 57049134600 scopus 로고    scopus 로고
    • C-jun N-terminal kinase regulates the interaction between 14-3-3 and Bad in ethanol-induced cell death
    • Han JY, Jeong EY, Kim YS, et al. C-jun N-terminal kinase regulates the interaction between 14-3-3 and Bad in ethanol-induced cell death. J Neurosci Res 2008; 86: 3221-3229
    • (2008) J Neurosci Res , vol.86 , pp. 3221-3229
    • Han, J.Y.1    Jeong, E.Y.2    Kim, Y.S.3
  • 46
    • 20844440200 scopus 로고    scopus 로고
    • P38 MAP kinase inhibition ameliorates cisplatin nephrotoxicity in mice
    • DOI 10.1152/ajprenal.00401.2004
    • Ramesh G, Reeves WB. p38 MAP kinase inhibition ameliorates cisplatin nephrotoxicity in mice. Am J Physiol Renal Physiol 2005; 289: 166-174 (Pubitemid 40863584)
    • (2005) American Journal of Physiology - Renal Physiology , vol.289 , Issue.1-58
    • Ramesh, G.1    Reeves, W.B.2
  • 47
    • 33750092536 scopus 로고    scopus 로고
    • Influence of SB203580 on cell apoptosis and P38MAPK in renal ischemia/reperfusion injury
    • Li R, Ding T, Liu X, et al. Influence of SB203580 on cell apoptosis and P38MAPK in renal ischemia/reperfusion injury. J Huazhong Univ Sci Technolog Med Sci 2006; 26: 50-52
    • (2006) J Huazhong Univ Sci Technolog Med Sci , vol.26 , pp. 50-52
    • Li, R.1    Ding, T.2    Liu, X.3
  • 48
    • 33745071527 scopus 로고    scopus 로고
    • Increased expression of p38 mitogen-activated protein kinase is related to the acute renal lesions induced by gentamicin
    • Volpini RA, Balbi AP, Costa RS, et al. Increased expression of p38 mitogen-activated protein kinase is related to the acute renal lesions induced by gentamicin. Braz J Med Biol Res 2006; 39: 817-823
    • (2006) Braz J Med Biol Res , vol.39 , pp. 817-823
    • Volpini, R.A.1    Balbi, A.P.2    Costa, R.S.3
  • 49
    • 0035501242 scopus 로고    scopus 로고
    • Cisplatin-induced apoptosis by translocation of endogenous Bax in mouse collecting duct cells
    • Lee RH, Song JM, Park MY, et al. Cisplatin-induced apoptosis by translocation of endogenous Bax in mouse collecting duct cells. Bio-chem Pharmacol 2001; 62: 1013-1023
    • (2001) Bio-chem Pharmacol , vol.62 , pp. 1013-1023
    • Lee, R.H.1    Song, J.M.2    Park, M.Y.3
  • 51
    • 33644661790 scopus 로고    scopus 로고
    • Bid deficiency ameliorates ischemic renal failure and delays animal death in C57BL/6 mice
    • Wei Q, Yin X, Wang M, et al. Bid deficiency ameliorates ischemic renal failure and delays animal death in C57BL/6 mice. Am J Physiol Renal Physiol 2006; 290: F35-F42
    • (2006) Am J Physiol Renal Physiol , vol.290
    • Wei, Q.1    Yin, X.2    Wang, M.3
  • 52
    • 38949146336 scopus 로고    scopus 로고
    • Protective role of the inhibitor of apoptosis protein, survivin, in toxin-induced acute renal failure
    • DOI 10.1096/fj.07-8882com
    • Kindt N, Menzebach A, Van de Wouwer M, et al. Protective role of the inhibitor of apoptosis protein, survivin, in toxin-induced acute renal failure. FASEB J 2008; 22: 510-521 (Pubitemid 351225587)
    • (2008) FASEB Journal , vol.22 , Issue.2 , pp. 510-521
    • Kindt, N.1    Menzebach, A.2    Van De Wouwer, M.3    Betz, I.4    De Vriese, A.5    Conway, E.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.