Characterisation of a novel monomeric lectin (AML) from Astragalus membranaceus with anti-proliferative activity

Food Chemistry

Volumn 122, Issue 3, 2010, Pages 589-595

  Yan, Qiaojuan ^a   Zhu, Lifen ^a   Kumar, Narasimha ^a   Jiang, Zhengqiang ^a   Huang, Linhua ^a  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

Author keywords

Anti proliferative activity; Astragalus membranaceus; characterisation; Hemagglutinating activity; Lectin

Indexed keywords

ANTINEOPLASTIC AGENT; ASTRAGALUS MEMBRANACEUS EXTRACT; GALACTOSE; GLYCOPROTEIN; LECTIN; O NITROPHENYL BETA DEXTRO GALACTOPYRANOSIDE; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG ISOLATION; FRACTIONATION; HELA CELL; HUMAN; HUMAN CELL; MOLECULAR WEIGHT; PH; PLANT ROOT; PROTEIN STABILITY; TEMPERATURE SENSITIVITY;

ASTRAGALUS MEMBRANACEUS;

EID: 77951638810     PISSN: 03088146     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.foodchem.2010.03.015     Document Type: Article

References (31)

1. Absar N., Yeasmin T., Raza M.S., Sarkar S.K., and Arisaka F. Single step purification, characterization and N-terminal sequences of a mannose specific lectin from mulberry seeds. The Protein Journal 24 (2005) 369-377
2. Damico D.C.S., Freire M.G.M., Gomes V.M., Toyama M.H., Marangoni S., Novello J.C., et al. Isolation and characterization of a lectin from Annona muricata seeds. Journal of Protein Chemistry 22 (2003) 655-661
3. De Mejia E.G., and Prisecaru V.I. Lectins as bioactive proteins: a potential in cancer treatment. Critical Reviews in Food Science and Nutrition 45 (2005) 425-445
4. Dhuna V., Kamboj S.S., Kaur A., Saxena A.K., Bhide S.V., Shanmugavel M., et al. Characterization of a lectin from Gonatanthus pumilus D. Don having anti-proliferative effect against human cancer cell lines. Protein and Peptide Letters 14 1 (2007) 71-78
5. Dubois M., Gilles K.A., Hamilton J.K., Rebers P.A., and Smith F. Colorimetric method for determination of sugars and related substances. Analytical Chemistry 28 (1956) 350-356
6. Kaur N., Dhuna V., Kamboj S.S., Agrewala J.N., and Singh J. A novel antiproliferative and antifungal lectin from Amaranthus viridis Linn seeds. Protein and Peptide Letters 13 (2006) 897-905
7. Kaur A., Singh J., Kamboj S.S., Sexana A.K., Pandita R.M., and Shamnugavel M. Isolation of an N-acetyl-d-glucosamine specific lectin from the rhizomes of Arundo donax with antiproliferative activity. Phytochemistry 66 16 (2005) 1933-1940
8. Konozy E.H.E., Bernardes E.S., Rosa C., Faca V., Greene L.J., and Ward R.J. Isolation, purification and physicochemical characterization of a d-galactose-binding lectin from seeds of Erythrina speciosa. Archives of Biochemistry and Biophysics 410 (2003) 222-229
9. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 (1970) 680-685
10. Lin P., and Ng T.B. Preparation and biological properties of a melibiose binding lectin from Bauhinia variegata seeds. Journal of Agricultural and Food Chemistry 56 22 (2008) 10481-10486
11. Loris R., Hamelryck T., Bouckaert J., and Wyns L. Legume lectin structure. Biochimica et Biophysica Acta 1383 1 (1998) 9-36
12. Lowry O.H., Rosebrough N.J., Farr A.L., and Randall R.J. Protein measurement with the folin phenol reagent. Journal Biological Chemistry 193 (1951) 265-275
13. Luo Y.T., Xu X.C., Liu J.W., Li J., Sun Y.S., Liu Z., et al. A novel mannose binding tuber lectin from Typhonium divaricatum (L.) Decne (family Araceae) with antiviral activity against HSV-II and anti-proliferative effect on human cancer cell lines. Journal of Biochemistry and Molecular Biology 40 (2007) 358-367
14. Ma X.Q., Duan J.A., Zhu D.Y., Dong T.T.X., and Tsim K.W.K. Species identification of Radix Astragali (Huangqi) by DNA sequence of its 5S-rRNA spacer domain. Phytochemistry 54 (2000) 363-368
15. Machuka J.S., Okeola O.G., Van Damme Els J.M., Chrispeels M.J., Van Leuvend F., and Peumans W.J. Isolation and partial characterization of galactose-specific lectins from African yam beans, Sphenostyles stenocarpa Harms. Phytochemistry 51 (1999) 721-728
16. Oliveira J.T.A., Melo V.M.M., Câmara M.F.L., Vasconcelos I.M., Beltramini L.M., Machado O.L.T., et al. Purification and physicochemical characterization of a cotyledonary lectin from Leuetzelburgia auriculata. Phytochemistry 61 (2002) 301-310
17. Pando S.C., Macedo M.L., Freire M.G., Toyama M.H., Novello J.C., and Marangoni S. Biochemical characterization of a lectin from Delonix regia seeds. Journal of Protein Chemistry 21 4 (2002) 279-285
18. Park W.B., Han S.K., Lee M.H., and Han K.H. Isolation and characterization of lectins from stem and leaves of Korean mistletoe (Viscum album var. coloratum) by affinity chromatography. Archives of Pharmacal Research 20 4 (1997) 306-312
19. Peumans W.J., and Van Damme E.J.M. Plant lectins versatile proteins with important perspectives in biotechnology. Biotechnology and Genetic Engineering Reviews 15 (1998) 199-228
20. Shao B.M., Xu W., Dai H., Tu P.F., Li Z.J., and Gao X.M. A study on the immune receptors for polysaccharides from the roots of Astragalus membranaceus, a Chinese medicinal herb. Biochemical and Biophysical Research Communications 320 (2004) 1103-1111
21. Sharon N. Lectins: carbohydrate-specific reagents and biological recognition molecules. Journal of Biological Chemistry 282 (2007) 2753-2764
22. Sinclair S. Chinese herbs: a clinical review of Astragalus, Ligusticum, and Schizandrae. Alternative Medicine Review 3 5 (1998) 338-344
23. Singh J., Singh J., and Kamboj S.S. A novel mitogenic and antiproliferative lectin from a wild cobra lily, Arisaema flavum. Biochemical and Biophysical Research Communications 318 (2004) 1057-1065
24. Sinha S., Gupta G., Vijayan M., and Surolia A. Subunit assembly of plant lectins. Current Opinion in Structural Biology 17 5 (2007) 498-505
25. Sitohy M., Doheim M., and Badr H. Isolation and characterization of a lectin with antifungal activity from Egyptian Pisum sativum seeds. Food Chemistry 104 (2007) 971-979
26. Suseelan K.N., Bhagwath A., Pandey R., and Gopalkrishna T. Characterization of ConA, a lectin from Canavalia cathartica Thouars seeds. Food Chemistry 104 (2007) 528-535
27. Vaz A.F.M., Costa R.M.P.B., Melo A.M.M.A., Oliva M.L.V., Santana L.A., Silva-Lucca R.A., et al. Biocontrol of Fusarium species by a novel lectin with low ecotoxicity isolated from Sebastiania jacobinensis. Food Chemistry 119 4 (2010) 1507-1513
28. Wong J.H., Chan H.Y.E., and Ng T.B. A mannose/glucose-specific lectin from Chinese evergreen chinkapin (Castanopsis chinensis). Biochimica et Biophysica Acta 1780 9 (2008) 1017-1022
29. Yan Q.J., Jiang Z.Q., Yang S.Q., Deng W., and Han L.J. A novel homodimeric lectin from Astragalus mongholicus with antifungal activity. Archives of Biochemistry and Biophysics 442 (2005) 72-81
30. Yan Q.J., Li Y.X., Jiang Z.Q., Yan S., Zhu L.F., and Ding Z.F. Antiproliferation and apoptosis of human tumor cell lines by a lectin (AMML) of Astragalus mongholicus. Phytomedicine 16 (2009) 586-593
31. Zacharius R.M., Zell T.E., Morrison J.H., and Woodlock J.J. Glycoprotein staining following electrophoresis on acrylamide gels. Analytical Biochemistry 30 (1969) 148-152