-
1
-
-
67349237973
-
Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2
-
Ahmed S, Thomas G et al (2009) Newly discovered breast cancer susceptibility loci on 3p24 and 17q23. 2. Nat Genet 41(5): 585-590.
-
(2009)
Nat Genet
, vol.41
, Issue.5
, pp. 585-590
-
-
Ahmed, S.1
Thomas, G.2
-
2
-
-
8844278362
-
A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans
-
Bond GL, Hu W et al (2004) A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans. Cell 119(5): 591-602.
-
(2004)
Cell
, vol.119
, Issue.5
, pp. 591-602
-
-
Bond, G.L.1
Hu, W.2
-
3
-
-
55549117831
-
Evolution of the mammalian transcription factor binding repertoire via transposable elements
-
Bourque G, Leong B et al (2008) Evolution of the mammalian transcription factor binding repertoire via transposable elements. Genome Res 11: 1752-1762.
-
(2008)
Genome Res
, vol.11
, pp. 1752-1762
-
-
Bourque, G.1
Leong, B.2
-
4
-
-
10744226888
-
Unbiased mapping of transcription factor binding sites along human chromosomes 21 and 22 points to widespread regulation of noncoding RNAs
-
Cawley S, Bekiranov S et al (2004) Unbiased mapping of transcription factor binding sites along human chromosomes 21 and 22 points to widespread regulation of noncoding RNAs. Cell 116(4): 499-509.
-
(2004)
Cell
, vol.116
, Issue.4
, pp. 499-509
-
-
Cawley, S.1
Bekiranov, S.2
-
5
-
-
61849132987
-
Association of ESR1 gene tagging SNPs with breast cancer risk
-
Dunning AM, Healey CS et al (2009) Association of ESR1 gene tagging SNPs with breast cancer risk. Hum Mol Genet 18(6): 1131-1139.
-
(2009)
Hum Mol Genet
, vol.18
, Issue.6
, pp. 1131-1139
-
-
Dunning, A.M.1
Healey, C.S.2
-
6
-
-
34250006413
-
Genome-wide association study identifies novel breast cancer susceptibility loci
-
Easton DF, Pooley KA et al (2007) Genome-wide association study identifies novel breast cancer susceptibility loci. Nature 447(7148): 1087-1093.
-
(2007)
Nature
, vol.447
, Issue.7148
, pp. 1087-1093
-
-
Easton, D.F.1
Pooley, K.A.2
-
7
-
-
70449103609
-
An oestrogen-receptor-α-bound human chromatin interactome
-
in press
-
Fullwood MJ, Liu MH et al (2009). An oestrogen-receptor-α-bound human chromatin interactome. Nature (in press).
-
(2009)
Nature
-
-
Fullwood, M.J.1
Liu, M.H.2
-
8
-
-
38849111754
-
MDM2 promoter polymorphism SNP309 contributes to tumor susceptibility: Evidence from 21 case-control studies
-
Hu Z, Jin G et al (2007) MDM2 promoter polymorphism SNP309 contributes to tumor susceptibility: evidence from 21 case-control studies. Cancer Epidemiol Biomarkers Prev 16(12): 2717-2723.
-
(2007)
Cancer Epidemiol Biomarkers Prev
, vol.16
, Issue.12
, pp. 2717-2723
-
-
Hu, Z.1
Jin, G.2
-
9
-
-
0345167800
-
TSC2 mediates cellular energy response to control cell growth and survival
-
Inoki K, Zhu T et al (2003) TSC2 mediates cellular energy response to control cell growth and survival. Cell 115(5): 577-590.
-
(2003)
Cell
, vol.115
, Issue.5
, pp. 577-590
-
-
Inoki, K.1
Zhu, T.2
-
10
-
-
20844449238
-
AMP-activated protein kinase induces a p53-dependent metabolic checkpoint
-
Jones RG, Plas DR et al (2005) AMP-activated protein kinase induces a p53-dependent metabolic checkpoint. Mol Cell 18(3): 283-293.
-
(2005)
Mol Cell
, vol.18
, Issue.3
, pp. 283-293
-
-
Jones, R.G.1
Plas, D.R.2
-
11
-
-
0016669094
-
Evolution at two levels in humans and chimpanzees
-
King MC, Wilson AC (1975) Evolution at two levels in humans and chimpanzees. Science 188(4184): 107-116.
-
(1975)
Science
, vol.188
, Issue.4184
, pp. 107-116
-
-
King, M.C.1
Wilson, A.C.2
-
12
-
-
15044364239
-
Regulatory polymorphisms underlying complex disease traits
-
Knight JC (2005) Regulatory polymorphisms underlying complex disease traits. J Mol Med 83(2): 97-109.
-
(2005)
J Mol Med
, vol.83
, Issue.2
, pp. 97-109
-
-
Knight, J.C.1
-
13
-
-
33745840203
-
5′-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments
-
Laderoute KR, Amin K et al (2006) 5′-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments. Mol Cell Biol 26(14): 5336-5347.
-
(2006)
Mol Cell Biol
, vol.26
, Issue.14
, pp. 5336-5347
-
-
Laderoute, K.R.1
Amin, K.2
-
14
-
-
34147204571
-
A single-nucleotide polymorphism in a half-binding site creates p53 and estrogen receptor control of vascular endothelial growth factor receptor 1
-
Menendez D, Inga A et al (2007) A single-nucleotide polymorphism in a half-binding site creates p53 and estrogen receptor control of vascular endothelial growth factor receptor 1. Mol Cell Biol 27(7): 2590-2600.
-
(2007)
Mol Cell Biol
, vol.27
, Issue.7
, pp. 2590-2600
-
-
Menendez, D.1
Inga, A.2
-
15
-
-
26444546442
-
An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival
-
Miller LD, Smeds J et al (2005) An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival. Proc Natl Acad Sci USA 102(38): 13550-13555.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.38
, pp. 13550-13555
-
-
Miller, L.D.1
Smeds, J.2
-
16
-
-
0142157701
-
Li-Fraumeni and related syndromes: Correlation between tumor type, family structure, and TP53 genotype
-
Olivier M, Goldgar DE et al (2003) Li-Fraumeni and related syndromes: correlation between tumor type, family structure, and TP53 genotype. Cancer Res 63(20): 6643-6650.
-
(2003)
Cancer Res
, vol.63
, Issue.20
, pp. 6643-6650
-
-
Olivier, M.1
Goldgar, D.E.2
-
17
-
-
7444235907
-
Cis-acting regulatory variation in the human genome
-
Pastinen T, Hudson TJ (2004) Cis-acting regulatory variation in the human genome. Science 306(5696): 647-650.
-
(2004)
Science
, vol.306
, Issue.5696
, pp. 647-650
-
-
Pastinen, T.1
Hudson, T.J.2
-
18
-
-
33645117454
-
Polymorphisms in the p53 pathway
-
Pietsch EC, Humbey O et al (2006) Polymorphisms in the p53 pathway. Oncogene 25(11): 1602-1611.
-
(2006)
Oncogene
, vol.25
, Issue.11
, pp. 1602-1611
-
-
Pietsch, E.C.1
Humbey, O.2
-
19
-
-
33750619348
-
Glucose metabolism and cancer
-
Shaw RJ (2006) Glucose metabolism and cancer. Curr Opin Cell Biol 18(6): 598-608.
-
(2006)
Curr Opin Cell Biol
, vol.18
, Issue.6
, pp. 598-608
-
-
Shaw, R.J.1
-
20
-
-
1542618348
-
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress
-
Shaw RJ, Kosmatka M et al (2004) The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress. Proc Natl Acad Sci USA 101(10): 3329-3335.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.10
, pp. 3329-3335
-
-
Shaw, R.J.1
Kosmatka, M.2
-
21
-
-
33646162638
-
Elucidating cis- and trans-regulatory variation using genetical genomics
-
Sladek R, Hudson TJ (2006) Elucidating cis- and trans-regulatory variation using genetical genomics. Trends Genet 22(5): 245-250.
-
(2006)
Trends Genet
, vol.22
, Issue.5
, pp. 245-250
-
-
Sladek, R.1
Hudson, T.J.2
-
22
-
-
25444519182
-
Pharmacologic modulation of glycogen synthase kinase-3beta promotes p53-dependent apoptosis through a direct Bax-mediated mitochondrial pathway in colorectal cancer cells
-
Tan J, Zhuang L et al (2005) Pharmacologic modulation of glycogen synthase kinase-3beta promotes p53-dependent apoptosis through a direct Bax-mediated mitochondrial pathway in colorectal cancer cells. Cancer Res 65(19): 9012-9020.
-
(2005)
Cancer Res
, vol.65
, Issue.19
, pp. 9012-9020
-
-
Tan, J.1
Zhuang, L.2
-
23
-
-
0036674617
-
Live or let die: The cell's response to p53
-
Vousden KH, Lu X (2002) Live or let die: the cell's response to p53. Nat Rev Cancer 2(8): 594-604.
-
(2002)
Nat Rev Cancer
, vol.2
, Issue.8
, pp. 594-604
-
-
Vousden, K.H.1
Lu, X.2
-
24
-
-
30344478870
-
A global map of p53 transcription-factor binding sites in the human genome
-
Wei CL, Wu Q et al (2006) A global map of p53 transcription-factor binding sites in the human genome. Cell 124(1): 207-219.
-
(2006)
Cell
, vol.124
, Issue.1
, pp. 207-219
-
-
Wei, C.L.1
Wu, Q.2
-
25
-
-
0036024955
-
Identification of unknown target genes of human transcription factors using chromatin immunoprecipitation
-
Weinmann AS, Farnham PJ (2002) Identification of unknown target genes of human transcription factors using chromatin immunoprecipitation. Methods 26(1): 37-47.
-
(2002)
Methods
, vol.26
, Issue.1
, pp. 37-47
-
-
Weinmann, A.S.1
Farnham, P.J.2
-
26
-
-
0036024957
-
Characterizing transcription factor binding sites using formaldehyde crosslinking and immunoprecipitation
-
Wells J, Farnham PJ (2002) Characterizing transcription factor binding sites using formaldehyde crosslinking and immunoprecipitation. Methods 26(1): 48-56.
-
(2002)
Methods
, vol.26
, Issue.1
, pp. 48-56
-
-
Wells, J.1
Farnham, P.J.2
-
27
-
-
33847057226
-
The evolutionary significance of cis-regulatory mutations
-
Wray GA (2007) The evolutionary significance of cis-regulatory mutations. Nat Rev Genet 8(3): 206-216.
-
(2007)
Nat Rev Genet
, vol.8
, Issue.3
, pp. 206-216
-
-
Wray, G.A.1
|