Role of genetic variation in the cannabinoid type 1 receptor gene (CNR1) in the pathophysiology of human obesity

Pharmacogenomics

Volumn 11, Issue 5, 2010, Pages 693-702

  Schleinitz, Dorit ^a   Carmienke, Solveig ^b   Böttcher, Yvonne ^b   Tnjes, Anke ^b   Berndt, Janin ^a   Klöting, Nora ^b   Enigk, Beate ^a   Müller, Ines ^a,b   Dietrich, Kerstin ^a   Breitfeld, Jana ^a   Scholz, Gerhard H ^c,d   Engeli, Stefan ^e   Stumvoll, Michael ^b   Blüher, Matthias ^b   Kovacs, Peter ^a  

^a UNIVERSITY HOSPITAL LEIPZIG   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

^c Chirurgische Abteilung   (Germany)

^d Institute for Preventive Medicine GmbH   (Germany)

^e HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

CNR1; Endocannabinoid system; Gene expression; Obesity; SNP

Indexed keywords

CANNABINOID 1 RECEPTOR; LEPTIN; MESSENGER RNA;

ADIPOSE TISSUE; ADULT; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; EXON; FEMALE; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; INSULIN SENSITIVITY; INTRON; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; OBESITY; ORAL GLUCOSE TOLERANCE TEST; PHENOTYPE; PROTEIN BLOOD LEVEL; RADIOIMMUNOASSAY; SINGLE NUCLEOTIDE POLYMORPHISM; SUBCUTANEOUS FAT;

ADIPOSE TISSUE; CASE-CONTROL STUDIES; ENDOCANNABINOIDS; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENE EXPRESSION; GENES; GENETIC VARIATION; GENOTYPE; GERMANY; HUMANS; INTRA-ABDOMINAL FAT; OBESITY; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, CANNABINOID; RNA, MESSENGER; SUBCUTANEOUS FAT;

EID: 77951604607     PISSN: 14622416     EISSN: 17448042     Source Type: Journal    
DOI: 10.2217/pgs.10.42     Document Type: Article

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