Mouse brain expression patterns of Spg7, Afg3l1, and Afg3l2 transcripts, encoding for the mitochondrial m-AAA protease

BMC Neuroscience

Volumn 11, Issue , 2010, Pages

  Sacco, Tiziana ^a   Boda, Enrica ^a   Hoxha, Eriola ^a   Pizzo, Riccardo ^a   Cagnoli, Claudia ^a   Brusco, Alfredo ^a   Tempia, Filippo ^a  

^a UNIVERSITY OF TURIN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; MITOCHONDRIAL PROTEIN; PARAPLEGIN; PROTEIN AFG3L1; PROTEIN AFG3L2; PROTEINASE; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATASE; AFG3L1 PROTEIN, MOUSE; AFG3L2 PROTEIN, MOUSE; M AAA PROTEASES; M-AAA PROTEASES; METALLOPROTEINASE; SPG7 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN STEM; CEREBELLUM; CEREBELLUM NUCLEUS; CORPUS STRIATUM; GENE EXPRESSION PROFILING; HIPPOCAMPUS; MITRAL CELL; MOTONEURON; MOUSE; NEOCORTEX; NONHUMAN; OLFACTORY BULB; PURKINJE CELL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THALAMUS; ANIMAL; BRAIN MAPPING; CYTOLOGY; ENERGY METABOLISM; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; HEREDITARY MOTOR SENSORY NEUROPATHY; METABOLISM; MITOCHONDRIAL MEMBRANE; NERVE CELL; SPINOCEREBELLAR DEGENERATION;

ADENOSINE TRIPHOSPHATASES; ANIMALS; BRAIN; BRAIN MAPPING; ENERGY METABOLISM; GENE EXPRESSION REGULATION, ENZYMOLOGIC; METALLOENDOPEPTIDASES; MICE; MITOCHONDRIAL MEMBRANES; NEURONS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPASTIC PARAPLEGIA, HEREDITARY; SPINOCEREBELLAR ATAXIAS;

EID: 77951604521     PISSN: None     EISSN: 14712202     Source Type: Journal    
DOI: 10.1186/1471-2202-11-55     Document Type: Article

References (19)

1. Arlt H, Tauer R, Feldmann H, Neupert W, Langer T. The YTA10-12 complex, an AAA protease with chaperone-like activity in the inner membrane of mitochondria. Cell 1996, 85:875-885. 10.1016/S0092-8674(00)81271-4, 8681382.
2. Arlt H, Steglich G, Perryman R, Guiard B, Neupert W, Langer T. The formation of respiratory chain complexes in mitochondria is under the proteolytic control of the m-AAA protease. EMBO J 1998, 17:4837-4847. 10.1093/emboj/17.16.4837, 1170813, 9707443.
3. Nolden M, Ehses S, Koppen M, Bernacchia A, Rugarli EI, Langer T. The m-AAA protease defective in hereditary spastic paraplegia controls ribosome assembly in mitochondria. Cell 2005, 123:277-289. 10.1016/j.cell.2005.08.003, 16239145.
4. Karlberg T, Berg S, Hammarström M, Sagemark J, Johansson I, Holmberg-Schiavone L, Schüler H. Crystal structure of the ATPase domain of the human AAA+ protein paraplegin/SPG7. PLoS One 2009, 4:e6975. 10.1371/journal.pone.0006975, 2734466, 19841671.
5. Ito K, Akiyama Y. Cellular functions, mechanism of action, and regulation of FtsH protease. Annu Rev Microbiol 2005, 211-231. 10.1146/annurev.micro.59.030804.121316, 15910274.
6. Casari G, De Fusco M, Ciarmatori S, Zeviani M, Mora M, Fernandez P, De Michele G, Filla A, Cocozza S, Marconi R, Dürr A, Fontaine B, Ballabio A. Spastic paraplegia and OXPHOS impairment caused by mutations in paraplegin, a nuclear-encoded mitochondrial metalloprotease. Cell 1998, 93:973-983. 10.1016/S0092-8674(00)81203-9, 9635427.
7. McDermott C, White K, Bushby K, Shaw P. Hereditary spastic paraparesis: a review of new developments. J Neurol Neurosurg Psychiatry 2000, 69:150-160. 10.1136/jnnp.69.2.150, 1737070, 10896685.
8. Di Bella D, Lazzaro F, Brusco A, Plumari M, Battaglia G, Pastore A, Finardi A, Cagnoli C, Tempia F, Frontali M, Veneziano L, Sacco T, Boda E, Brussino A, Bonn F, Castellotti B, Baratta S, Mariotti C, Gellera C, Fracasso V, Magri S, Langer T, Plevani P, Di Donato S, Muzi-Falconi M, Taroni F. Mutations in the mitochondrial protease gene AFG3L2 cause dominant hereditary ataxia SCA28. Nat Genet 2010, 42:313-331. 10.1038/ng.544, 20208537.
9. Ferreirinha F, Quattrini A, Pirozzi M, Valsecchi V, Dina G, Broccoli V, Auricchio A, Piemonte F, Tozzi G, Gaeta L, Casari G, Ballabio A, Rugarli EI. Axonal degeneration in paraplegin-deficient mice is associated with abnormal mitochondria and impairment of axonal transport. J Clin Invest 2004, 113:231-242. 311437, 14722615.
10. Maltecca F, Aghaie A, Schroeder DG, Cassina L, Taylor BA, Phillips SJ, Malaguti M, Previtali S, Guénet JL, Quattrini A, Cox GA, Casari G. The mitochondrial protease AFG3L2 is essential for axonal development. J Neurosci 2008, 28:2827-2836. 10.1523/JNEUROSCI.4677-07.2008, 18337413.
11. Martinelli P, La Mattina V, Bernacchia A, Magnoni R, Cerri F, Cox G, Quattrini A, Casari G, Rugarli EI. Genetic interaction between the m-AAA protease isoenzymes reveals novel roles in cerebellar degeneration. Hum Mol Genet 2009, 18:2001-2013. 10.1093/hmg/ddp124, 19289403.
12. Maltecca F, Magnoni R, Cerri F, Cox GA, Quattrini A, Casari G. Haploinsufficiency of AFG3L2, the gene responsible for spinocerebellar ataxia type 28, causes mitochondria-mediated Purkinje cell dark degeneration. J Neurosci 2009, 29:9244-9254. 10.1523/JNEUROSCI.1532-09.2009, 19625515.
13. Atorino L, Silvestri L, Koppen M, Cassina L, Ballabio A, Marconi R, Langer T, Casari G. Loss of m-AAA protease in mitochondria causes complex I deficiency and increased sensitivity to oxidative stress in hereditary spastic paraplegia. J Cell Biol 2003, 163:777-787. 10.1083/jcb.200304112, 2173682, 14623864.
14. Koppen M, Metodiev MD, Casari G, Rugarli EI, Langer T. Variable and tissue-specific subunit composition of mitochondrial m-AAA protease complexes linked to hereditary spastic paraplegia. Mol Cell Biol 2007, 27:758-767. 10.1128/MCB.01470-06, 1800790, 17101804.
15. Boda E, Pini A, Hoxha E, Parolisi R, Tempia F. Selection of reference genes for quantitative real time RT-PCR studies in mouse brain. J Mol Neurosci 2009, 37:238-253. 10.1007/s12031-008-9128-9, 18607772.
16. Pettus EH, Betarbet R, Cottrell B, Wallace DC, Madyastha V, Greenamyre JT. Immunocytochemical characterization of the mitochondrially encoded ND1 subunit of complex I (NADH: ubiquinone oxidoreductase) in rat brain. J Neurochem 2000, 75:383-392. 10.1046/j.1471-4159.2000.0750383.x, 10854284.
17. Mariotti C, Brusco A, Di Bella D, Cagnoli C, Seri M, Gellera C, Di Donato S, Taroni F. Spinocerebellar ataxia type 28: A novel autosomal dominant cerebellar ataxia characterized by slow progression and ophthalmoparesis. Cerebellum 2008, 7:184-188. 10.1007/s12311-008-0053-9, 18769991.
18. Paxinos G, Franklin KBJ. The Mouse Brain in Stereotaxic Coordinates 2001, Academic Press.
19. Bortone DS, Mitchell K, Manis PB. Developmental time course of potassium channel expression in the rat cochlear nucleus. Hearing Research 2006, 211:114-125. 10.1016/j.heares.2005.10.012, 16337757.