Solid-state surface acidity and pH-stability profiles of amorphous quinapril hydrochloride and silicate formulations

Journal of Pharmaceutical Sciences

Volumn 99, Issue 6, 2010, Pages 2786-2799

  Hailu, Shumet A ^a   Bogner, Robin H ^b  

^a MILLENNIUM PHARMACEUTICALS INC   (United States)

^b UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

Acidity function; Aerosil; Amorphous; Chemical stability; Cogrinding; Equivalent pH; Milling; Neusilin; pH grade of silicates; pH stability profile; Quinapril hydrochloride; Silicates; Stability; Surface acidity; Surface pH

Indexed keywords

QUINAPRIL; SILICATE;

ACIDITY; ARTICLE; DRUG FORMULATION; DRUG STABILITY; PH; SOLID STATE;

EID: 77951598480     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.22051     Document Type: Article

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