Solid state 13C NMR investigation of impact of annealing in lyophilized glasses

Journal of Pharmaceutical Sciences

Volumn 97, Issue 10, 2008, Pages 4336-4346

  Luthra, Suman A ^a   Pikal, Michael J ^a   Utz, Marcel ^a,b  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b University of Virginia   (United States)

Author keywords

Amorphous state; Annealing; Freeze drying lyophilization; Local dynamics; Molecular mobility; Solid state NMR spectroscopy; T1 relaxation time; T1 relaxation time

Indexed keywords

ASPARTAME; CARBOHYDRATE; GLASS; SUCROSE; TREHALOSE;

ARTICLE; CALORIMETRY; CARBON NUCLEAR MAGNETIC RESONANCE; CORRELATION ANALYSIS; FREEZE DRYING; HEATING; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SOLID STATE; CHEMISTRY; HEAT; METHODOLOGY;

ASPARTAME; FREEZE DRYING; GLASS; HOT TEMPERATURE; MAGNETIC RESONANCE SPECTROSCOPY; TREHALOSE;

EID: 55749099492     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21316     Document Type: Article

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