Synthesis and surface modification of highly fluorescent gold nanoclusters and their exploitation for cellular labeling

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

Volumn 7575, Issue , 2010, Pages

  Lin, Cheng An J ^a   Lee, Chih Hsien ^a   Hsieh, Jiun Tai ^a   Yu, Wan Chun ^a   Yang, Hong Zhi ^a   Li, Jimmy K ^d   Sperling, Ralph ^b   Wang, Hsueh Hsiao ^c   Yeh, Hung I ^c   Parak, Wolfgang J ^b   Chang, Walter H ^a  

^a CHUNG YUAN CHRISTIAN UNIVERSITY   (Taiwan)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

^c MACKAY MEMORIAL HOSPITAL   (Taiwan)

^d NATIONAL UNIVERSITY OF TAINAN   (Taiwan)

Author keywords

Bioconjugation; Biotinylation; Cell labeling; Fluorescent gold nanoclusters; Lipoic acid; Near infrared; PEGylation

Indexed keywords

BIO-CONJUGATION; BIOTINYLATIONS; CELL LABELING; GOLD NANOCLUSTER; LIPOIC ACIDS; NEAR INFRARED; PEGYLATION;

ACIDS; BLOOD VESSEL PROSTHESES; ENDOTHELIAL CELLS; FLUORESCENCE; GOLD; INFRARED DEVICES; LABELING; NANOCLUSTERS; SEMICONDUCTOR QUANTUM DOTS;

GOLD COMPOUNDS;

EID: 77951593751     PISSN: 16057422     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.841540     Document Type: Conference Paper

References (47)

1. Zheng, J., Zhang, C. W., and Dickson, R. M., "Highly fluorescent, water-soluble, size-tunable gold quantum dots," Phys. Rev. Lett., 93(7), 077402, (2004).
2. Bigioni, T. P., Whetten, R. L., and Dag, O., "Near-infrared luminescence from small gold nanocrystals," J. Phys. Chem. B, 104(30), 6983-6986, (2000).
3. Huang, T. and Murray, R. W., "Visible luminescence of water-soluble monolayer- protected gold clusters," J. Phys. Chem. B, 105(50), 12498-12502, (2001). (Pubitemid 35338300)
4. Peyser, L. A., Vinson, A. E., Bartko, A. P., and Dickson, R. M., "Photoactivated fluorescence from individual silver nanoclusters," Science, 291(5501), 103-106, (2001).
5. Zheng, J. and Dickson, R. M., "Individual water-soluble dendrimer-encapsulated silver nanodot fluorescence," J. Am. Chem. Soc., 124(47), 13982-13983, (2002). (Pubitemid 35386836)
6. Link, S., Beeby, A., FitzGerald, S., El-Sayed, M. A., Schaaff, T. G., and Whetten, R. L., "Visible to infrared luminescence from a 28-atom gold cluster," J. Phys. Chem. B, 106(13), 3410-3415, (2002). (Pubitemid 35290238)
7. Yang, Y. and Chen, S., "Surface Manipulation of the Electronic Energy of Subnanometer-Sized Gold Clusters: An Electrochemical and Spectroscopic Investigation," Nano Lett., 3(1), 75-79, (2003). (Pubitemid 37161857)
8. Zheng, J., Petty, J. T., and Dickson, R. M., "High quantum yield blue emission from water-soluble Au-8 nanodots," J. Am. Chem. Soc., 125(26), 7780-7781, (2003). (Pubitemid 36782137)
9. Negishi, Y., Takasugi, Y., Sato, S., Yao, H., Kimura, K., and Tsukuda, T., "Magic-numbered Au-n clusters protected by glutathione monolayers (n=18, 21, 25, 28, 32, 39): Isolation and spectroscopic characterization," J. Am. Chem. Soc., 126(21), 6518-6519, (2004). (Pubitemid 38697329)
10. Schaaff, T. G. and Whetten, R. L., "Giant gold-glutathione cluster compounds: Intense optical activity in metal-based transitions," J. Phys. Chem. B, 104(12), 2630-2641, (2000).
11. Garzon, I. L., Reyes-Nava, J. A., Rodriguez-Hernandez, J. I., Sigal, I., Beltran, M. R., and Michaelian, K., "Chirality in bare and passivated gold nanoclusters," Phys. Rev. B, 66(7), 073403, (2002).
12. Gautier, C. and Bürgi, T., "Chiral Inversion of Gold Nanoparticles," J. Am. Chem. Soc., 130(22), 7077-7084, (2008).
13. Roman-Velazquez, C. E., Noguez, C., and Garzon, I. L., "Circular Dichroism Simulated Spectra of Chiral Gold Nanoclusters: A Dipole Approximation," J. Phys. Chem. B, 107(44), 12035-12038, (2003).
14. Crespo, P., Litran, R., Rojas, T. C., Multigner, M., de la Fuente, J. M., Sanchez-Lopez, J. C., Garcia, M. A., Hernando, A., Penades, S., and Fernandez, A., "Permanent magnetism, magnetic anisotropy, and hysteresis of thiolcapped gold nanoparticles," Phys. Rev. Lett., 93(8), 087204, (2004).
15. Lee, T. H., Gonzalez, J. I., Zheng, J., and Dickson, R. M., "Single-molecule optoelectronics," Acc. Chem. Res., 38(7), 534-541, (2005).
16. Vosch, T., Antoku, Y., Hsiang, J. C., Richards, C. I., Gonzalez, J. I., and Dickson, R. M., "Strongly emissive individual DNA-encapsulated Ag nanoclusters as single-molecule fluorophores," Proc. Natl. Acad. Sci. U. S. A., 104(31), 12616-12621, (2007). (Pubitemid 47255203)
17. Huang, C. C., Yang, Z., Lee, K. H., and Chang, H. T., "Synthesis of highly fluorescent gold nanoparticles for sensing Mercury(II)," Angew. Chem., Int. Ed., 46(36), 6824-6828, (2007). (Pubitemid 47425796)
18. Triulzi, R. C., Micic, M., Giordani, S., Serry, M., Chiou, W. A., and Leblanc, R. M., "Immunoasssay based on the antibody-conjugated PAMAM-dendrimer-gold quantum dot complex," Chem. Commun., 48, 5068-5070, (2006). (Pubitemid 44866536)
19. Huang, C. C., Chiang, C. K., Lin, Z. H., Lee, K. H., and Chang, H. T., "Bioconjugated gold nanodots and nanoparticles for protein assays based on photoluminescence quenching," Anal. Chem., 80(5), 1497-1504, (2008).
20. Alivisatos, A. P., "Semiconductor Clusters, Nanocrystals, and Quantum Dots," Science, 271(16), 933-937, (1996).
21. Link, S. and El-Sayed, M. A., "Optical properties and ultrafast dynamics of metallic nanocrystals," Annu. Rev. Phys. Chem., 54, 331-366, (2003).
22. Alvarez, M. M., Khoury, J. T., Schaaff, T. G., Shafigullin, M. N., Vezmar, I., and Whetten, R. L., "Optical absorption spectra of nanocrystal gold molecules," J. Phys. Chem. B, 101(19), 3706-3712, (1997). (Pubitemid 127581121)
23. Schaaff, T. G., Shafigullin, M. N., Khoury, J. T., Vezmar, I., Whetten, R. L., Cullen, W. G., First, P. N., GutierrezWing, C., Ascensio, J., and JoseYacaman, M. J., "Isolation of smaller nanocrystal au molecules: Robust quantum effects in optical spectra," J. Phys. Chem. B, 101(40), 7885-7891, (1997). (Pubitemid 127576548)
24. Hostetler, M. J., Wingate, J. E., Zhong, C. J., Harris, J. E., Vachet, R. W., Clark, M. R., Londono, J. D., Green, S. J., Stokes, J. J., Wignall, G. D., Glish, G. L., Porter, M. D., Evans, N. D., and Murray, R. W., "Alkanethiolate gold cluster molecules with core diameters from 1.5 to 5.2 nm: Core and monolayer properties as a function of core size," Langmuir, 14(1), 17-30, (1998).
25. Apell, P., Monreal, R., and Lundqvist, S., "Photoluminescence of noble metals," Phys. Scr., 38, 174-179, (1988).
26. Chen, S., Ingram, R. S., Hostetler, M. J., Pietron, J. J., Murray, R. W., Schaaff, T. G., Khoury, J. T., Alvarez, M. M., and Whetten, R. L., "Gold nanoelectrodes of varied size: transition to molecule-like charging," Science, 280(5372), 2098-2101, (1998). (Pubitemid 28366198)
27. Lee, D., Donkers, R. L., Wang, G. L., Harper, A. S., and Murray, R. W., "Electrochemistry and optical absorbance and luminescence of molecule-like Au-38 nanoparticles," J. Am. Chem. Soc., 126(19), 6193-6199, (2004). (Pubitemid 38637987)
28. Lin, Z. Y., Kanters, R. P. F., and Mingos, D. M. P., "Closed-Shell Electronic Requirements for Condensed Clusters of the Group-11 Elements," Inorg. Chem., 30(1), 91-95, (1991).
29. Bruchez, M., Jr., Moronne, M., Gin, P., Weiss, S., and Alivisatos, A. P., "Semiconductor nanocrystals as fluorescent biological labels," Small, 281(5385), 2013-2016, (1998).
30. Chan, W. C. and Nie, S., "Quantum dot bioconjugates for ultrasensitive nonisotopic detection," Small, 281(5385), 2016-2018, (1998).
31. Smith, A. M., Dave, S., Nie, S. M., True, L., and Gao, X. H., "Multicolor quantum dots for molecular diagnostics of cancer," Expert. Rev. Mol. Diagn., 6(2), 231-244, (2006). (Pubitemid 44167151)
32. Alivisatos, A., Gu, W., and Larabell, C., "Quantum Dots as Cellular Probes," Annu. Rev. Biomed. Eng., 7, 55-76, (2005).
33. Michalet, X., Pinaud, F. F., Bentolila, L. A., Tsay, J. M., Doose, S., Li, J. J., Sundaresan, G., Wu, A. M., Gambhir, S. S., and Weiss, S., "Quantum dots for live cells, in vivo imaging, and diagnostics," Science, 307(5709), 538-544, (2005). (Pubitemid 40165671)
34. Hardman, R., "A toxicologic review of quantum dots: toxicity depends on physicochemical and environmental factors," Environ. Health Perspect., 114(2), 165-172, (2006). (Pubitemid 43193634)
35. Diez, I., Pusa, M., Kulmala, S., Jiang, H., Walther, A., Goldmann, A. S., Muller, A. H. E., Ikkala, O., and Ras, R. H. A., "Color Tunability and Electrochemiluminescence of Silver Nanoclusters," Angew. Chem., Int. Ed., 48(12), 2122-2125, (2009).
36. Richards, C. I., Choi, S., Hsiang, J. C., Antoku, Y., Vosch, T., Bongiorno, A., Tzeng, Y. L., and Dickson, R. M., "Oligonucleotide- stabilized Ag nanocluster fluorophores," J. Am. Chem. Soc., 130(15), 5038-5039, (2008).
37. Xie, J. P., Zheng, Y. G., and Ying, J. Y., "Protein-Directed Synthesis of Highly Fluorescent Gold Nanoclusters," J. Am. Chem. Soc., 131(3), 888-889, (2009).
38. Shang, L. and Dong, S. J., "Facile preparation of water-soluble fluorescent silver nanoclusters using a polyelectrolyte template," Chem. Commun., 9, 1088-1090, (2008). (Pubitemid 351311319)
39. Lin, C.-A. J., Yang, T. Y., Lee, C. H., Huang, S. H., Sperling, R. A., Zanella, M., Li, J. K., Shen, J. L., Wang, H. H., Yeh, H. I., Parak, W. J., and Chang, W. H., "Synthesis, characterization, and bioconjugation of fluorescent gold nanoclusters toward biological labeling applications," ACS Nano, 3(2), 395-401, (2009).
40. Huang, C. C., Liao, H. Y., Shiang, Y. C., Lin, Z. H., Yang, Z., and Chang, H. T., "Synthesis of wavelength-tunable luminescent gold and gold/silver nanodots," J. Mater. Chem., 19(6), 755-759, (2009).
41. Lin, C.-A. J., Lee, C.-H., Hsieh, J.-T., Wang, H.-H., Li, J. K., Shen, J.-L., Chan, W.-H., Yeh, H.-I., and Chang, W. H., "Synthesis of Fluorescent Metallic Nanoclusters toward Biomedical Application: Recent Progress and Present Challenges," J. Med. Biol. Eng., 29(6), Accepted, (2009).
42. Jana, N. R. and Peng, X. G., "Single-phase and gram-scale routes toward nearly monodisperse Au and other noble metal nanocrystals," J. Am. Chem. Soc., 125(47), 14280-14281, (2003).
43. Sperling, R. A., Liedl, T., Duhr, S., Kudera, S., Zanella, M., Lin, C.-A. J., Chang, W. H., Braun, D., and Parak, W. J., "Size determination of (bio-) conjugated water-soluble colloidal nanoparticles - a comparison of different techniques," J. Phys. Chem. C, 111(31), 11552-11559, (2007). (Pubitemid 47280550)
44. Fee, C. J. and Alstine, J. M. V., "Prediction of the Viscosity Radius and the Size Exclusion Chromatography Behavior of PEGylated Proteins," Bioconjugate Chem., 15(6), 1304-1313, (2004).
45. Lin, C.-A. J., Sperling, R. A., Li, J. K., Yang, T.-Y., Li, P.-Y., Zanella, M., Chang, W. H., and Parak, W. J., "Design of an amphiphilic polymer for nanoparticle coating and functionalization," Small, 4(3), 334-341, (2008). (Pubitemid 351421263)
46. Duan, H. W. and Nie, S. M., "Etching colloidal gold nanocrystals with hyperbranched and multivalent polymers: A new route to fluorescent and water-soluble atomic clusters," J. Am. Chem. Soc., 129(9), 2412-+, (2007).
47. Lin, S. Y., Chen, N. T., Sum, S. P., Lo, L. W., and Yang, C. S., "Ligand exchanged photoluminescent gold quantum dots functionalized with leading peptides for nuclear targeting and intracellular imaging," Chem. Commun., 39, 4762-4764, (2008).