Isoproterenol and cAMP block ERK phosphorylation and enhance [Ca 2+]i increases and oxygen consumption by muscarinic receptor stimulation in rat parotid and submandibular acinar cells

Journal of Biological Chemistry

Volumn 285, Issue 18, 2010, Pages 13337-13348

  Soltoff, Stephen P ^a   Hedden, Lee ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACINAR CELLS; ADRENERGIC RECEPTORS; CARBACHOL; CELL LINES; DIACYLGLYCEROL; EPIDERMAL GROWTH FACTOR RECEPTORS; EXCHANGE PROTEINS; EXTRACELLULAR SIGNALS; FORSKOLIN; INHIBITORY EFFECT; INHIBITORY SITES; ISOPROTERENOL; MIMETICS; MUSCARINIC LIGANDS; MUSCARINIC RECEPTOR; OXYGEN CONSUMPTION; PHORBOL 12 MYRISTATE 13 ACETATES; PROTEIN KINASE; PROTEIN KINASE A; PROTEIN KINASE C; RAT PAROTID; SALIVARY GLANDS; SECOND MESSENGER; SIGNALING PATHWAYS;

ACTIVATION ANALYSIS; CALCIUM; CELL CULTURE; GLYCEROL; LEAKAGE (FLUID); LIGANDS; OXYGEN; PHOSPHORYLATION; PROTEINS; STEEL METALLOGRAPHY; SUGARS;

FETAL MONITORING;

6 N BENZOYL CYCLIC AMP; 8 (4 CHLOROPHENYLTHIO) CYCLIC AMP; BUCLADESINE; CALCIUM ION; CARBACHOL; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; DIACYLGLYCEROL; ENZYME ACTIVATOR; EPIDERMAL GROWTH FACTOR RECEPTOR; EXCHANGE PROTEINS DIRECTLY ACTIVATED BY CYCLIC AMP ACTIVATOR; FORSKOLIN; INOSITOL TRISPHOSPHATE; ISOPRENALINE; MITOGEN ACTIVATED PROTEIN KINASE; MUSCARINIC RECEPTOR; PHORBOL 13 ACETATE 12 MYRISTATE; PURINERGIC P2X7 RECEPTOR; RAF PROTEIN; UNCLASSIFIED DRUG;

ACINAR CELL; ANIMAL CELL; ARTICLE; CELL LINE; CELL TYPE; CONTROLLED STUDY; DOWNSTREAM PROCESSING; DRUG MECHANISM; ENZYME INHIBITION; MALE; NONHUMAN; OXYGEN CONSUMPTION; PAROTID GLAND; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SECRETION; SUBMANDIBULAR GLAND;

ADRENERGIC BETA-AGONISTS; ANIMALS; CALCIUM; CARBACHOL; CARCINOGENS; CELL LINE, TRANSFORMED; CELL LINE, TUMOR; CHOLINERGIC AGONISTS; CYCLIC AMP; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FORSKOLIN; GUANINE NUCLEOTIDE EXCHANGE FACTORS; ISOPROTERENOL; MALE; OXYGEN CONSUMPTION; PAROTID GLAND; PHOSPHORYLATION; PROTEIN KINASE C; RAF KINASES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, ADRENERGIC, BETA; RECEPTORS, MUSCARINIC; RECEPTORS, PURINERGIC P2; SECOND MESSENGER SYSTEMS; SUBMANDIBULAR GLAND; TETRADECANOYLPHORBOL ACETATE;

RATTUS;

EID: 77951560145     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.112094     Document Type: Article

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