-
1
-
-
44349142294
-
Common variants near MC4R are associated with fat mass, weight and risk of obesity
-
DOI 10.1038/ng.140, PII NG140
-
Loos RJ, Lindgren CM, Li S, et al: Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet 2008; 40: 768-775. (Pubitemid 351748863)
-
(2008)
Nature Genetics
, vol.40
, Issue.6
, pp. 768-775
-
-
Loos, R.J.F.1
Lindgren, C.M.2
Li, S.3
-
2
-
-
58149163142
-
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
-
Willer CJ, Speliotes EK, Loos RJ, et al: Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet 2009; 41: 25-34.
-
(2009)
Nat Genet
, vol.41
, pp. 25-34
-
-
Willer, C.J.1
Speliotes, E.K.2
Loos, R.J.3
-
3
-
-
0031668219
-
A frameshift mutation in MC4R associated with dominantly inherited human obesity [1]
-
DOI 10.1038/2404
-
Yeo GS, Farooqi IS, Aminian S, Halsall DJ, Stanhope RG, O'Rahilly S: A frameshift mutation in MC4R associated with dominantly inherited human obesity. Nat Genet 1998; 20: 111-112. (Pubitemid 28455438)
-
(1998)
Nature Genetics
, vol.20
, Issue.2
, pp. 111-112
-
-
Yeo, G.S.H.1
Farooqi, I.S.2
Aminian, S.3
Halsall, D.J.4
Stanhope, R.G.5
O'Rahilly, S.6
-
4
-
-
0031662163
-
A frameshift mutation in human MC4R is associated with a dominant form of obesity [2]
-
DOI 10.1038/2407
-
Vaisse C, Clement K, Guy-Grand B, Froguel P: A frameshift mutation in human MC4R is associated with a dominant form of obesity. Nat Genet 1998; 20: 113-114. (Pubitemid 28455439)
-
(1998)
Nature Genetics
, vol.20
, Issue.2
, pp. 113-114
-
-
Vaisse, C.1
Clement, K.2
Guy-Grand, B.3
Froguel, P.4
-
5
-
-
0037456768
-
Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene
-
DOI 10.1056/NEJMoa022050
-
Farooqi IS, Keogh JM, Yeo GS, Lank EJ, Cheetham T, O'Rahilly S: Clinical spectrum of obesity and mutations in the melanocortin-receptor gene. N Engl J Med 2003; 348: 1085-1095. (Pubitemid 36337319)
-
(2003)
New England Journal of Medicine
, vol.348
, Issue.12
, pp. 1085-1095
-
-
Farooqi, I.S.1
Keogh, J.M.2
Yeo, G.S.H.3
Lank, E.J.4
Cheetham, T.5
O'Rahilly, S.6
-
6
-
-
62349130691
-
Common genetic variation near MC4R is associated with eating behaviour patterns in European populations
-
Stutzmann F, Cauchi S, Durand E, Calvacanti-Proença C, Pigeyre M, Hartikainen AL, Sovio U, Tichet J, Marre M, Weill J, Balkau B, Potoczna N, Laitinen J, Elliott P, Järvelin MR, Horber F, Meyre D, Froguel P: Common genetic variation near MC4R is associated with eating behaviour patterns in European populations. Int J Obes (Lond) 2009; 33: 373-378.
-
(2009)
Int J Obes (Lond)
, vol.33
, pp. 373-378
-
-
Stutzmann, F.1
Cauchi, S.2
Durand, E.3
Calvacanti-Proença, C.4
Pigeyre, M.5
Hartikainen, A.L.6
Sovio, U.7
Tichet, J.8
Marre, M.9
Weill, J.10
Balkau, B.11
Potoczna, N.12
Laitinen, J.13
Elliott, P.14
Järvelin, M.R.15
Horber, F.16
Meyre, D.17
Froguel, P.18
-
7
-
-
51449116347
-
Non-replication of genomewide-based associations between common variants in INSIG2 and PFKP and obesity in studies of 18,014 Danes
-
Andreasen CH, Mogensen MS, Borch-Johnsen K, Sandbæk A, Lauritzen T, Sørensen TI, Hansen L, Almind K, Jørgensen T, Pedersen O, Hansen T: Non-replication of genomewide-based associations between common variants in INSIG2 and PFKP and obesity in studies of 18,014 Danes. PLoS ONE 2008; 3: e2872.
-
(2008)
PLoS ONE
, vol.3
-
-
Andreasen, C.H.1
Mogensen, M.S.2
Borch-Johnsen, K.3
Sandbæk, A.4
Lauritzen, T.5
Sørensen, T.I.6
Hansen, L.7
Almind, K.8
Jørgensen, T.9
Pedersen, O.10
Hansen, T.11
-
9
-
-
23044444928
-
Heritability of body composition measured by DXA in the diabetes heart study
-
Hsu FC, Lenchik L, Nicklas BJ, Lohman K, Register TC, Mychaleckyj J, Langefeld CD, Freedman BI, Bowden DW, Carr JJ: Heritability of body composition measured by DXA in the diabetes heart study. Obes Res 2005; 13: 312-319.
-
(2005)
Obes Res
, vol.13
, pp. 312-319
-
-
Hsu, F.C.1
Lenchik, L.2
Nicklas, B.J.3
Lohman, K.4
Register, T.C.5
Mychaleckyj, J.6
Langefeld, C.D.7
Freedman, B.I.8
Bowden, D.W.9
Carr, J.J.10
-
10
-
-
65549170326
-
Effect of birth size and proportionality on BMI and skinfold thickness in early adolescence: Prospective birth cohort study
-
Araújo CL, Hallal PC, Nader GA, Neutzling MB, Defátima Vieira M, Menezes AM, Victora CG: Effect of birth size and proportionality on BMI and skinfold thickness in early adolescence: prospective birth cohort study. Eur J Clin Nutr 2009; 63: 634-639.
-
(2009)
Eur J Clin Nutr
, vol.63
, pp. 634-639
-
-
Araújo, C.L.1
Hallal, P.C.2
Nader, G.A.3
Neutzling, M.B.4
Defátima Vieira, M.5
Menezes, A.M.6
Victora, C.G.7
-
11
-
-
0034620969
-
Association between postnatal catch-up growth and obesity in childhood: Prospective cohort study
-
Ong KK, Ahmed ML, Emmett PM, Preece MA, Dunger DB: Association between postnatal catch-up growth and obesity in childhood: prospective cohort study. BMJ 2000; 320: 967-971.
-
(2000)
BMJ
, vol.320
, pp. 967-971
-
-
Ong, K.K.1
Ahmed, M.L.2
Emmett, P.M.3
Preece, M.A.4
Dunger, D.B.5
-
12
-
-
34248594090
-
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
-
Frayling TM, Timpson NJ, Weedon MN, et al: A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 2007; 316: 889-894.
-
(2007)
Science
, vol.316
, pp. 889-894
-
-
Frayling, T.M.1
Timpson, N.J.2
Weedon, M.N.3
-
13
-
-
34249777814
-
Variation in FTO contributes to childhood obesity and severe adult obesity
-
DOI 10.1038/ng2048, PII NG2048
-
Dina C, Meyre D, Gallina S, Durand E, Körner A, Jacobson P, Carlsson LM, Kiess W, Vatin V, Lecoeur C, Delplanque J, Vaillant E, Pattou F, Ruiz J, Weill J, Levy-Marchal C, Horber F, Potoczna N, Hercberg S, Le Stunff C, Bougnères P, Kovacs P, Marre M, Balkau B, Cauchi S, Chèvre JC, Froguel P: Variation in FTO contributes to childhood obesity and severe adult obesity. Nat Genet 2007; 39: 724-726. (Pubitemid 46848595)
-
(2007)
Nature Genetics
, vol.39
, Issue.6
, pp. 724-726
-
-
Dina, C.1
Meyre, D.2
Gallina, S.3
Durand, E.4
Korner, A.5
Jacobson, P.6
Carlsson, L.M.S.7
Kiess, W.8
Vatin, V.9
Lecoeur, C.10
Delplanque, J.11
Vaillant, E.12
Pattou, F.13
Ruiz, J.14
Weill, J.15
Levy-Marchal, C.16
Horber, F.17
Potoczna, N.18
Hercberg, S.19
Le Stunff, C.20
Bougneres, P.21
Kovacs, P.22
Marre, M.23
Balkau, B.24
Cauchi, S.25
Chevre, J.-C.26
Froguel, P.27
more..
-
14
-
-
34547625955
-
Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits
-
DOI 10.1371/journal.pgen.0030115
-
Scuteri A, Sanna S, Chen WM, Uda M, Albai G, Strait J, Najjar S, Nagaraja R, Orrú M, Usala G, Dei M, Lai S, Maschio A, Busonero F, Mulas A, Ehret GB, Fink AA, Weder AB, Cooper RS, Galan P, Chakravarti A, Schlessinger D, Cao A, Lakatta E, Abecasis GR: Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS Genet 2007; 3: e115. (Pubitemid 47203970)
-
(2007)
PLoS Genetics
, vol.3
, Issue.7
, pp. 1200-1210
-
-
Scuteri, A.1
Sanna, S.2
Chen, W.-M.3
Uda, M.4
Albai, G.5
Strait, J.6
Najjar, S.7
Nagaraja, R.8
Orru, M.9
Usala, G.10
Dei, M.11
Lai, S.12
Maschio, A.13
Busonero, F.14
Mulas, A.15
Ehret, G.B.16
Fink, A.A.17
Weder, A.B.18
Cooper, R.S.19
Galan, P.20
Chakravarti, A.21
Schlessinger, D.22
Cao, A.23
Lakatta, E.24
Abecasis, G.R.25
more..
-
15
-
-
42049117134
-
The association between the FTO gene and fat mass in humans develops by the postnatal age of two weeks
-
DOI 10.1210/jc.2007-2343
-
López-Bermejo A, Petry CJ, Díaz M, Sebastiani G, de Zegher F, Dunger DB, Ibáñez L: The association between the FTO gene and fat mass in humans develops by the postnatal age of two weeks. J Clin Endocrinol Metab 2008; 93: 1501-1505. (Pubitemid 351519755)
-
(2008)
Journal of Clinical Endocrinology and Metabolism
, vol.93
, Issue.4
, pp. 1501-1505
-
-
Lopez-Bermejo, A.1
Petry, C.J.2
Diaz, M.3
Sebastiani, G.4
De Zegher, F.5
Dunger, D.B.6
Ibanez, L.7
-
16
-
-
36949017061
-
Cord serum visfatin at term birth: Maternal smoking unmasks the relation to foetal growth
-
DOI 10.1111/j.1365-2265.2007.03002.x
-
López-Bermejo A, de Zegher F, Díaz-Silva M, Vicente MP, Valls C, Ibáñez L: Cord serum visfatin at term birth: maternal smoking unmasks the relation to foetal growth. Clin Endocrinol (Oxf) 2008; 68: 77-81. (Pubitemid 350243485)
-
(2008)
Clinical Endocrinology
, vol.68
, Issue.1
, pp. 77-81
-
-
Lopez-Bermejo, A.1
De Zegher, F.2
Diaz-Silva, M.3
Vicente, M.P.4
Valls, C.5
Ibanez, L.6
-
17
-
-
33744952660
-
Early development of adiposity and insulin resistance after catch-up weight gain in small-for-gestational-age children
-
DOI 10.1210/jc.2005-2778
-
Ibáñez L, Valls C, Ong K, Dunger D, de Zegher F: Early development of adiposity and insulin resistance following catch-up weight gain in low birth weight children. J Clin Endocrinol Metab 2006; 91: 2153-2158. (Pubitemid 43854998)
-
(2006)
Journal of Clinical Endocrinology and Metabolism
, vol.91
, Issue.6
, pp. 2153-2158
-
-
Ibanez, L.1
Ong, K.2
Dunger, D.B.3
De Zegher, F.4
-
18
-
-
0034051912
-
Measurement precision of body composition variables using the lunar DPX-L densitometer
-
Kiebzak GM, Leamy LJ, Pierson LM, Nord RH, Zhang ZY: Measurement precision of body composition variables using the lunar DPX-L densitometer. J Clin Densitom 2000; 3: 35-41.
-
(2000)
J Clin Densitom
, vol.3
, pp. 35-41
-
-
Kiebzak, G.M.1
Leamy, L.J.2
Pierson, L.M.3
Nord, R.H.4
Zhang, Z.Y.5
-
19
-
-
0036794478
-
SNPkit: An efficient approach to systematic evaluation of candidate single nucleotide polymorphisms in public databases
-
Hao K, Niu T, Sangokoya C, Li J, Xu X: SNPkit: an efficient approach to systematic evaluation of candidate single nucleotide polymorphisms in public databases. Biotechniques 2002; 33: 822-828. (Pubitemid 35168067)
-
(2002)
BioTechniques
, vol.33
, Issue.4
, pp. 822-830
-
-
Hao, K.1
Niu, T.2
Sangokoya, C.3
Li, J.4
Xu, X.5
-
20
-
-
51649128621
-
Obesity-associated genetic variation in FTO is associated with diminished satiety
-
Wardle J, Carnell S, Haworth CM, Farooqi IS, O'Rahilly S, Plomin R: Obesity-associated genetic variation in FTO is associated with diminished satiety. J Clin Endocrinol Metab 2008; 93: 3640-3643.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, pp. 3640-3643
-
-
Wardle, J.1
Carnell, S.2
Haworth, C.M.3
Farooqi, I.S.4
O'Rahilly, S.5
Plomin, R.6
-
21
-
-
0242515957
-
The detection of gene-environment interaction for continuous traits: Should we deal with measurement error by bigger studies or better measurement?
-
Wong MY, Day NE, Luan JA, Chan KP, Wareham NJ: The detection of gene-environment interaction for continuous traits: should we deal with measurement error by bigger studies or better measurement? Int J Epidemiol 2003; 32: 51-57.
-
(2003)
Int J Epidemiol
, vol.32
, pp. 51-57
-
-
Wong, M.Y.1
Day, N.E.2
Luan, J.A.3
Chan, K.P.4
Wareham, N.J.5
-
22
-
-
64549158008
-
Replication and extension of genomewide association study results for obesity in 4923 adults from northern Sweden
-
Renström F, Payne F, Nordström A, Brito EC, Rolandsson O, Hallmans G, Barroso I, Nordström P, Franks PW, GIANT Consortium: Replication and extension of genomewide association study results for obesity in 4923 adults from northern Sweden. Hum Mol Genet 2009; 18: 1489-1496.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 1489-1496
-
-
Renström, F.1
Payne, F.2
Nordström, A.3
Brito, E.C.4
Rolandsson, O.5
Hallmans, G.6
Barroso, I.7
Nordström, P.8
Franks, P.W.9
Consortium, G.10
-
23
-
-
62749100569
-
Variants near MC4R are associated with obesity and influence obesity-related quantitative traits in a population of middle-aged people: Studies of 14,940 Danes
-
Zobel DP, Andreasen CH, Grarup N, Eiberg H, Sørensen TI, Sandbaek A, Lauritzen T, Borch-Johnsen K, Jørgensen T, Pedersen O, Hansen T: Variants near MC4R are associated with obesity and influence obesity-related quantitative traits in a population of middle-aged people: studies of 14,940 Danes. Diabetes 2009; 58: 757-764.
-
(2009)
Diabetes
, vol.58
, pp. 757-764
-
-
Zobel, D.P.1
Andreasen, C.H.2
Grarup, N.3
Eiberg, H.4
Sørensen, T.I.5
Sandbaek, A.6
Lauritzen, T.7
Borch-Johnsen, K.8
Jørgensen, T.9
Pedersen, O.10
Hansen, T.11
-
24
-
-
67349103704
-
Combined effects of MC4R and FTO common genetic variants on obesity in European general populations
-
Cauchi S, Stutzmann F, Cavalcanti-Proença C, Durand E, Pouta A, Hartikainen AL, Marre M, Vol S, Tammelin T, Laitinen J, Gonzalez-Izquierdo A, Blakemore AI, Elliott P, Meyre D, Balkau B, Järvelin MR, Froguel P: Combined effects of MC4R and FTO common genetic variants on obesity in European general populations. J Mol Med 2009; 87: 537-546.
-
(2009)
J Mol Med
, vol.87
, pp. 537-546
-
-
Cauchi, S.1
Stutzmann, F.2
Cavalcanti-Proença, C.3
Durand, E.4
Pouta, A.5
Hartikainen, A.L.6
Marre, M.7
Vol, S.8
Tammelin, T.9
Laitinen, J.10
Gonzalez-Izquierdo, A.11
Blakemore, A.I.12
Elliott, P.13
Meyre, D.14
Balkau, B.15
Järvelin, M.R.16
Froguel, P.17
-
25
-
-
67649744249
-
Investigation of the locus near MC4R with childhood obesity in Americans of European and African ancestry
-
Grant SF, Bradfield JP, Zhang H, Wang K, Kim CE, Annaiah K, Santa E, Glessner JT, Thomas K, Garris M, Frackelton EC, Otieno FG, Shaner JL, Smith RM, Imielinski M, Chiavacci RM, Li M, Berkowitz RI, Hakonarson H: Investigation of the locus near MC4R with childhood obesity in Americans of European and African ancestry. Obesity (Silver Spring) 2009; 17: 1461-1465.
-
(2009)
Obesity (Silver Spring)
, vol.17
, pp. 1461-1465
-
-
Grant, S.F.1
Bradfield, J.P.2
Zhang, H.3
Wang, K.4
Kim, C.E.5
Annaiah, K.6
Santa, E.7
Glessner, J.T.8
Thomas, K.9
Garris, M.10
Frackelton, E.C.11
Otieno, F.G.12
Shaner, J.L.13
Smith, R.M.14
Imielinski, M.15
Chiavacci, R.M.16
Li, M.17
Berkowitz, R.I.18
Hakonarson, H.19
-
26
-
-
0025031812
-
No adjustments are needed for multiple comparisons
-
Rothman KJ: No adjustments are needed for multiple comparisons. Epidemiology 1990; 1: 43-46.
-
(1990)
Epidemiology
, vol.1
, pp. 43-46
-
-
Rothman, K.J.1
|