메뉴 건너뛰기




Volumn 51, Issue 5, 2010, Pages 1538-1546

Hepatitis B virus activates deoxynucleotide synthesis in nondividing hepatocytes by targeting the R2 gene

Author keywords

[No Author keywords available]

Indexed keywords

BROXURIDINE; DEOXYRIBONUCLEOTIDE; DEOXYRIBONUCLEOTIDE TRIPHOSPHATE; GENOMIC DNA; GENOMIC RNA; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; RIBONUCLEOTIDE REDUCTASE; UNCLASSIFIED DRUG; VIRUS PROTEIN;

EID: 77951481786     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.23519     Document Type: Article
Times cited : (39)

References (36)
  • 1
    • 1542316127 scopus 로고    scopus 로고
    • Hepatitis B Virus Infection - Natural History and Clinical Consequences
    • DOI 10.1056/NEJMra031087
    • Ganem D, Prince AM. Hepatitis B virus infection - natural history and clinical consequences. N Engl J Med 2004;350:1118-1129. (Pubitemid 38298992)
    • (2004) New England Journal of Medicine , vol.350 , Issue.11 , pp. 1118-1129
    • Ganem, D.1    Prince, A.M.2
  • 2
    • 0023080494 scopus 로고
    • The molecular biology of the hepatitis B viruses
    • Ganem D, Varmus HE. The molecular biology of the hepatitis B viruses. Annu Rev Biochem 1987;56:651-693.
    • (1987) Annu Rev Biochem , vol.56 , pp. 651-693
    • Ganem, D.1    Varmus, H.E.2
  • 3
    • 9444275911 scopus 로고    scopus 로고
    • Effects of cell cycle on telomerase activity and on hepatitis B virus replication in HepG2 2.2.15 cells
    • Huang YQ, Wang LW, Yan SN, Gong ZJ. Effects of cell cycle on telomerase activity and on hepatitis B virus replication in HepG2 2.2.15 cells. Hepatobiliary Pancreat Dis Int 2004;3:543-547.
    • (2004) Hepatobiliary Pancreat Dis Int , vol.3 , pp. 543-547
    • Huang, Y.Q.1    Wang, L.W.2    Yan, S.N.3    Gong, Z.J.4
  • 4
    • 0024464828 scopus 로고
    • Deoxyribonucleoside triphosphate pools in regenerating rat liver: Effect of hydroxyurea and exogenous deoxypyrimidines
    • DOI 10.1016/0304-4165(89)90095-0
    • Rottgen V, Rabes HM. Deoxyribonucleoside triphosphate pools in regenerating rat liver: effect of hydroxyurea and exogenous deoxypyrimidines. Biochim Biophys Acta 1989;992:349-354. (Pubitemid 19220897)
    • (1989) Biochimica et Biophysica Acta - General Subjects , vol.992 , Issue.3 , pp. 349-354
    • Rottgen, V.1    Rabes, H.M.2
  • 7
    • 22644445475 scopus 로고    scopus 로고
    • Analysis of mammalian cell cytoplasm with electrophoresis in nanometer inner diameter capillaries
    • DOI 10.1002/elan.200403240
    • Woods LA, Powell PR, Paxon TL, Ewing AG. Analysis of mammalian cell cytoplasm with electrophoresis in nanometer inner diameter capillaries. Electroanalysis 2005;17:1192-1197. (Pubitemid 41024947)
    • (2005) Electroanalysis , vol.17 , Issue.13 , pp. 1192-1197
    • Woods, L.A.1    Powell, P.R.2    Paxon, T.L.3    Ewing, A.G.4
  • 8
    • 0030782535 scopus 로고    scopus 로고
    • Natural history of chronic hepatitis B virus infection: An immunopathological study
    • Chu CM, Liaw YF. Natural history of chronic hepatitis B virus infection: an immunopathological study. J Gastroenterol Hepatol 1997;12: S218-S222. (Pubitemid 27504895)
    • (1997) Journal of Gastroenterology and Hepatology , vol.12 , Issue.9-10
    • Chu, C.-M.1    Liaw, Y.-F.2
  • 11
    • 27944488330 scopus 로고    scopus 로고
    • Autorepression of Rfx1 gene expression: Functional conservation from yeast to humans in response to DNA replication arrest
    • DOI 10.1128/MCB.25.23.10665-10673.2005
    • Lubelsky Y, Reuven N, Shaul Y. Autorepression of rfx1 gene expression: functional conservation from yeast to humans in response to DNA replication arrest. Mol Cell Biol 2005;25:10665-10673. (Pubitemid 41681985)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.23 , pp. 10665-10673
    • Lubelsky, Y.1    Reuven, N.2    Shaul, Y.3
  • 12
    • 0037565188 scopus 로고    scopus 로고
    • A long HBV transcript encoding pX is inefficiently exported from the nucleus
    • DOI 10.1016/S0042-6822(03)00156-9
    • Doitsh G, Shaul Y. A long HBV transcript encoding pX is inefficiently exported from the nucleus. Virology 2003;309:339-349. (Pubitemid 36579227)
    • (2003) Virology , vol.309 , Issue.2 , pp. 339-349
    • Doitsh, G.1    Shaul, Y.2
  • 13
    • 0035881827 scopus 로고    scopus 로고
    • HBV infection of cell culture: Evidence for multivalent and cooperative attachment
    • DOI 10.1093/emboj/20.16.4443
    • Paran N, Geiger B, Shaul Y. HBV infection of cell culture: evidence for multivalent and cooperative attachment. EMBO J 2001;20: 4443-4453. (Pubitemid 32772039)
    • (2001) EMBO Journal , vol.20 , Issue.16 , pp. 4443-4453
    • Paran, N.1    Geiger, B.2    Shaul, Y.3
  • 16
    • 0141706664 scopus 로고    scopus 로고
    • C-Abl Tyrosine Kinase Selectively Regulates p73 Nuclear Matrix Association
    • DOI 10.1074/jbc.M301051200
    • Ben-Yehoyada M, Ben-Dor I, Shaul Y. c-Abl tyrosine kinase selectively regulates p73 nuclear matrix association. J Biol Chem 2003;278:34475-34482. (Pubitemid 37553295)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.36 , pp. 34475-34482
    • Ben-Yehoyada, M.1    Ben-Dor, I.2    Shaul, Y.3
  • 17
    • 0023103125 scopus 로고
    • An improved immunocytochemical procedure for high-sensitivity detection of incorporated bromodeoxyuridine
    • Beisker W, Dolbeare F, Gray JW. An improved immunocytochemical procedure for high-sensitivity detection of incorporated bromodeoxyuridine. Cytometry 1987;8:235-239. (Pubitemid 17046495)
    • (1987) Cytometry , vol.8 , Issue.2 , pp. 235-239
    • Beisker, W.1    Dolbeare, F.2    Gray, J.W.3
  • 18
    • 0029996147 scopus 로고    scopus 로고
    • In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
    • Naldini L, Blomer U, Gallay P, Ory D, Mulligan R, Gage FH, et al. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 1996;272:263-267.
    • (1996) Science , vol.272 , pp. 263-267
    • Naldini, L.1    Blomer, U.2    Gallay, P.3    Ory, D.4    Mulligan, R.5    Gage, F.H.6
  • 20
    • 0024402491 scopus 로고
    • Enzymatic assay for deoxyribonucleoside triphosphates using synthetic oligonucleotides as template primers
    • Sherman PA, Fyfe JA. Enzymatic assay for deoxyribonucleoside triphosphates using synthetic oligonucleotides as template primers. Anal Biochem 1989;180:222-226.
    • (1989) Anal Biochem , vol.180 , pp. 222-226
    • Sherman, P.A.1    Fyfe, J.A.2
  • 21
    • 0023371479 scopus 로고
    • Hepatitis B virus produced by transfected Hep G2 cells causes hepatitis in chimpanzees
    • Acs G, Sells MA, Purcell RH, Price P, Engle R, Shapiro M, et al. Hepatitis B virus produced by transfected Hep G2 cells causes hepatitis in chimpanzees. Proc Natl Acad Sci USA 1987;84:4641-4644.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 4641-4644
    • Acs, G.1    Sells, M.A.2    Purcell, R.H.3    Price, P.4    Engle, R.5    Shapiro, M.6
  • 22
    • 0026769877 scopus 로고
    • The mechanism of inhibition of hepatitis B virus replication by the carbocyclic analog of 2′-deoxyguanosine
    • Price PM, Banerjee R, Jeffrey AM, Acs G. The mechanism of inhibition of hepatitis B virus replication by the carbocyclic analog of 2′- deoxyguanosine. HEPATOLOGY 1992;16:8-12.
    • (1992) HEPATOLOGY , vol.16 , pp. 8-12
    • Price, P.M.1    Banerjee, R.2    Jeffrey, A.M.3    Acs, G.4
  • 23
    • 0022254166 scopus 로고
    • The inhibition of ribonucleoside diphosphate reductase by hydroxyurea, guanazole and pyrazoloimidazole (IMPY)
    • Moore EC, Hurlbert RB. The inhibition of ribonucleoside diphosphate reductase by hydroxyurea, guanazole and pyrazoloimidazole (IMPY). Pharmacol Ther 1985;27:167-196.
    • (1985) Pharmacol Ther , vol.27 , pp. 167-196
    • Moore, E.C.1    Hurlbert, R.B.2
  • 24
    • 33646359442 scopus 로고    scopus 로고
    • Regulation of mammalian ribonucleotide reduction and dNTP pools after DNA damage and in resting cells
    • DOI 10.1074/jbc.M512894200
    • Hakansson P, Hofer A, Thelander L. Regulation of mammalian ribonucleotide reduction and dNTP pools after DNA damage and in resting cells. J Biol Chem 2006;281:7834-7841. (Pubitemid 43847398)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.12 , pp. 7834-7841
    • Hakansson, P.1    Hofer, A.2    Thelander, L.3
  • 25
    • 34447118849 scopus 로고    scopus 로고
    • P53R2-dependent ribonucleotide reduction provides deoxyribonucleotides in quiescent human fibroblasts in the absence of induced DNA damage
    • DOI 10.1074/jbc.M701310200
    • Pontarin G, Ferraro P, Hakansson P, Thelander L, Reichard P, Bianchi V. p53R2-dependent ribonucleotide reduction provides deoxyribonucleotides in quiescent human fibroblasts in the absence of induced DNA damage. J Biol Chem 2007;282:16820-16828. (Pubitemid 47093192)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.23 , pp. 16820-16828
    • Pontarin, G.1    Ferraro, P.2    Hakansson, P.3    Thelander, L.4    Reichard, P.5    Bianchi, V.6
  • 27
    • 0023925454 scopus 로고
    • Interactions between deoxyribonucleotide and DNA synthesis
    • Reichard P. Interactions between deoxyribonucleotide and DNA synthesis. Annu Rev Biochem 1988;57:349-374.
    • (1988) Annu Rev Biochem , vol.57 , pp. 349-374
    • Reichard, P.1
  • 28
    • 33748288087 scopus 로고    scopus 로고
    • Molecular functions and biological roles of hepatitis B virus x protein
    • DOI 10.1111/j.1349-7006.2006.00299.x
    • Tang H, Oishi N, Kaneko S, Murakami S. Molecular functions and biological roles of hepatitis B virus x protein. Cancer Sci 2006;97: 977-983. (Pubitemid 44322542)
    • (2006) Cancer Science , vol.97 , Issue.10 , pp. 977-983
    • Tang, H.1    Oishi, N.2    Kaneko, S.3    Murakami, S.4
  • 29
    • 0032483576 scopus 로고    scopus 로고
    • The DNA replication and damage checkpoint pathways induce transcription by inhibition of the Crt1 repressor
    • DOI 10.1016/S0092-8674(00)81601-3
    • Huang M, Zhou Z, Elledge SJ. The DNA replication and damage checkpoint pathways induce transcription by inhibition of the Crt1 repressor. Cell 1998;94:595-605. (Pubitemid 28427578)
    • (1998) Cell , vol.94 , Issue.5 , pp. 595-605
    • Huang, M.1    Zhou, Z.2    Elledge, S.J.3
  • 30
    • 0028905281 scopus 로고
    • Interaction of EF-C/RFX-1 with the inverted repeat of viral enhancer regions is required for transactivation
    • David E, Garcia AD, Hearing P. Interaction of EF-C/RFX-1 with the inverted repeat of viral enhancer regions is required for transactivation. J Biol Chem 1995;270:8353-8360.
    • (1995) J Biol Chem , vol.270 , pp. 8353-8360
    • David, E.1    Garcia, A.D.2    Hearing, P.3
  • 31
    • 0030843563 scopus 로고    scopus 로고
    • The transcriptional activation and repression domains of RFX1, a context-dependent regulator, can mutually neutralize their activities
    • DOI 10.1093/nar/25.18.3621
    • Katan Y, Agami R, Shaul Y. The transcriptional activation and repression domains of RFX1, a context-dependent regulator, can mutually neutralize their activities. Nucleic Acids Res 1997;25: 3621-3628. (Pubitemid 27390180)
    • (1997) Nucleic Acids Research , vol.25 , Issue.18 , pp. 3621-3628
    • Katan, Y.1    Agami, R.2    Shaul, Y.3
  • 32
    • 34047210411 scopus 로고    scopus 로고
    • TP53 mutations and hepatocellular carcinoma: Insights into the etiology and pathogenesis of liver cancer
    • DOI 10.1038/sj.onc.1210279, PII 1210279
    • Hussain SP, Schwank J, Staib F, Wang XW, Harris CC. TP53 mutations and hepatocellular carcinoma: insights into the etiology and pathogenesis of liver cancer. Oncogene 2007;26:2166-2176. (Pubitemid 46536641)
    • (2007) Oncogene , vol.26 , Issue.15 , pp. 2166-2176
    • Hussain, S.P.1    Schwank, J.2    Staib, F.3    Wang, X.W.4    Harris, C.C.5
  • 33
    • 1842588435 scopus 로고    scopus 로고
    • The Ribonucleotide Reductase R1 Homolog of Murine Cytomegalovirus Is Not a Functional Enzyme Subunit but Is Required for Pathogenesis?
    • DOI 10.1128/JVI.78.8.4278-4288.2004
    • Lembo D, Donalisio M, Hofer A, Cornaglia M, Brune W, Koszinowski U, et al. The ribonucleotide reductase R1 homolog of murine cytomegalovirus is not a functional enzyme subunit but is required for pathogenesis. J Virol 2004;78:4278-4288. (Pubitemid 38437231)
    • (2004) Journal of Virology , vol.78 , Issue.8 , pp. 4278-4288
    • Lembo, D.1    Donalisio, M.2    Hofer, A.3    Cornaglia, M.4    Brune, W.5    Koszinowski, U.6    Thelander, L.7    Landolfo, S.8
  • 35
    • 33947396752 scopus 로고    scopus 로고
    • The mimivirus genome encodes a mitochondrial carrier that transports dATP and dTTP
    • DOI 10.1128/JVI.02386-06
    • Monne M, Robinson AJ, Boes C, Harbour ME, Fearnley IM, Kunji ER. The mimivirus genome encodes a mitochondrial carrier that transports dATP and dTTP. J Virol 2007;81:3181-3186. (Pubitemid 46456627)
    • (2007) Journal of Virology , vol.81 , Issue.7 , pp. 3181-3186
    • Monne, M.1    Robinson, A.J.2    Boes, C.3    Harbour, M.E.4    Fearnley, I.M.5    Kunji, E.R.S.6
  • 36
    • 33745246534 scopus 로고    scopus 로고
    • Intracellular Nucleotides Act as Critical Prosurvival Factors by Binding to Cytochrome C and Inhibiting Apoptosome
    • DOI 10.1016/j.cell.2006.05.026, PII S0092867406006684
    • Chandra D, Bratton SB, Person MD, Tian Y, Martin AG, Ayres M, et al. Intracellular nucleotides act as critical prosurvival factors by binding to cytochrome C and inhibiting apoptosome. Cell 2006;125:1333-1346. (Pubitemid 43929090)
    • (2006) Cell , vol.125 , Issue.7 , pp. 1333-1346
    • Chandra, D.1    Bratton, S.B.2    Person, M.D.3    Tian, Y.4    Martin, A.G.5    Ayres, M.6    Fearnhead, H.O.7    Gandhi, V.8    Tang, D.G.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.