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Volumn 84, Issue 10, 2010, Pages 5032-5042

Anti-gp41 antibodies cloned from HIV-infected patients with broadly neutralizing serologic activity

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY GP41; NEUTRALIZING ANTIBODY; UNCLASSIFIED DRUG; VIRUS FUSION PROTEIN;

EID: 77951480441     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.00154-10     Document Type: Article
Times cited : (50)

References (60)
  • 2
    • 0021924655 scopus 로고
    • Virus envelope protein of HTLV-III represents major target antigen for antibodies in AIDS patients
    • Barin, F., M. F. McLane, J. S. Allan, T. H. Lee, J. E. Groopman, and M. Essex. 1985. Virus envelope protein of HTLV-III represents major target antigen for antibodies in AIDS patients. Science 228:1094-1096. (Pubitemid 15227369)
    • (1985) Science , vol.228 , Issue.4703 , pp. 1094-1096
    • Barin, F.1    McLane, M.F.2    Allan, J.S.3
  • 4
    • 0029957873 scopus 로고    scopus 로고
    • Human antibody responses to HIV type 1 glycoprotein 41 cloned in phage display libraries suggest three major epitopes are recognized and give evidence for conserved antibody motifs in antigen binding
    • Binley, J. M., H. J. Ditzel, C. F. Barbas, N. Sullivan, J. Sodroski, P. W. Parren, and D. R. Burton. 1996. Human antibody responses to HIV type 1 glycoprotein 41 cloned in phage display libraries suggest three major epitopes are recognized and give evidence for conserved antibody motifs in antigen binding. AIDS Res. Hum. Retroviruses 12:911-924.
    • (1996) AIDS Res. Hum. Retroviruses , vol.12 , pp. 911-924
    • Binley, J.M.1    Ditzel, H.J.2    Barbas, C.F.3    Sullivan, N.4    Sodroski, J.5    Parren, P.W.6    Burton, D.R.7
  • 5
    • 0028028425 scopus 로고
    • Antigenic implications of human immunodeficiency virus type 1 envelope quaternary structure: Oligomer-specific and -sensitive monoclonal antibodies
    • Broder, C. C., P. L. Earl, D. Long, S. T. Abedon, B. Moss, and R. W. Doms. 1994. Antigenic implications of human immunodeficiency virus type 1 envelope quaternary structure: oligomer-specific and -sensitive monoclonal antibodies. Proc. Natl. Acad. Sci. U. S. A. 91:11699-11703.
    • (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , pp. 11699-11703
    • Broder, C.C.1    Earl, P.L.2    Long, D.3    Abedon, S.T.4    Moss, B.5    Doms, R.W.6
  • 8
    • 0030970693 scopus 로고    scopus 로고
    • Core structure of gp41 from the HIV envelope glycoprotein
    • Chan, D. C., D. Fass, J. M. Berger, and P. S. Kim. 1997. Core structure of gp41 from the HIV envelope glycoprotein. Cell 89:263-273.
    • (1997) Cell , vol.89 , pp. 263-273
    • Chan, D.C.1    Fass, D.2    Berger, J.M.3    Kim, P.S.4
  • 11
    • 0028355456 scopus 로고
    • Native oligomeric human immunodeficiency virus type 1 envelope glycoprotein elicits diverse monoclonal antibody reactivities
    • Earl, P. L., C. C. Broder, D. Long, S. A. Lee, J. Peterson, S. Chakrabarti, R. W. Doms, and B. Moss. 1994. Native oligomeric human immunodeficiency virus type 1 envelope glycoprotein elicits diverse monoclonal antibody reactivities. J. Virol. 68:3015-3026. (Pubitemid 24129751)
    • (1994) Journal of Virology , vol.68 , Issue.5 , pp. 3015-3026
    • Earl, P.L.1    Broder, C.C.2    Long, D.3    Lee, S.A.4    Peterson, J.5    Chakrabarti, S.6    Doms, R.W.7    Moss, B.8
  • 12
    • 0030997127 scopus 로고    scopus 로고
    • Epitope map of human immunodeficiency virus type 1 gp41 derived from 47 monoclonal antibodies produced by immunization with oligomeric envelope protein
    • Earl, P. L., C. C. Broder, R. W. Doms, and B. Moss. 1997. Epitope map of human immunodeficiency virus type 1 gp41 derived from 47 monoclonal antibodies produced by immunization with oligomeric envelope protein. J. Virol. 71:2674-2684.
    • (1997) J. Virol. , vol.71 , pp. 2674-2684
    • Earl, P.L.1    Broder, C.C.2    Doms, R.W.3    Moss, B.4
  • 13
    • 0036889127 scopus 로고    scopus 로고
    • Antigenic properties of the human immunodeficiency virus transmembrane glycoprotein during cell-cell fusion
    • DOI 10.1128/JVI.76.23.12123-12134.2002
    • Finnegan, C. M., W. Berg, G. K. Lewis, and A. L. DeVico. 2002. Antigenic properties of the human immunodeficiency virus transmembrane glycoprotein during cell-cell fusion. J. Virol. 76:12123-12134. (Pubitemid 35304311)
    • (2002) Journal of Virology , vol.76 , Issue.23 , pp. 12123-12134
    • Finnegan, C.M.1    Berg, W.2    Lewis, G.K.3    Devico, A.L.4
  • 14
    • 0023669119 scopus 로고
    • Detection of a fusion peptide sequence in the transmembrane protein of human immunodeficiency virus
    • Gallaher, W. R. 1987. Detection of a fusion peptide sequence in the transmembrane protein of human immunodeficiency virus. Cell 50:327-328.
    • (1987) Cell , vol.50 , pp. 327-328
    • Gallaher, W.R.1
  • 15
    • 0023260942 scopus 로고
    • Diagnosis of AIDS by using a 12-amino acid peptide representing an immunodominant epitope of the human immunodeficiency virus
    • Gnann, J. W., Jr., P. L. Schwimmbeck, J. A. Nelson, A. B. Truax, and M. B. Oldstone. 1987. Diagnosis of AIDS by using a 12-amino acid peptide representing an immunodominant epitope of the human immunodeficiency virus. J. Infect. Dis. 156:261-267.
    • (1987) J. Infect. Dis. , vol.156 , pp. 261-267
    • Gnann Jr., J.W.1    Schwimmbeck, P.L.2    Nelson, J.A.3    Truax, A.B.4    Oldstone, M.B.5
  • 16
    • 0023196107 scopus 로고
    • Fine mapping of an immunodominant domain in the transmembrane glycoprotein of human immunodeficiency virus
    • Gnann, J. W., Jr., J. A. Nelson, and M. B. Oldstone. 1987. Fine mapping of an immunodominant domain in the transmembrane glycoprotein of human immunodeficiency virus. J. Virol. 61:2639-2641.
    • (1987) J. Virol. , vol.61 , pp. 2639-2641
    • Gnann Jr., J.W.1    Nelson, J.A.2    Oldstone, M.B.3
  • 17
    • 70350320582 scopus 로고    scopus 로고
    • Broad neutralization of human immunodeficiency virus type 1 mediated by plasma antibodies against the gp41 membrane proximal external region
    • Gray, E. S., M. C. Madiga, M. L. Moore, K. Mlisana, S. S. A. Karim, J. M. Binley, G. M. Shaw, J. R. Mascola, and L. Morris. 2009. Broad neutralization of human immunodeficiency virus type 1 mediated by plasma antibodies against the gp41 membrane proximal external region. J. Virol. 83:11265-11274.
    • (2009) J. Virol. , vol.83 , pp. 11265-11274
    • Gray, E.S.1    Madiga, M.C.2    Moore, M.L.3    Mlisana, K.4    Karim, S.S.A.5    Binley, J.M.6    Shaw, G.M.7    Mascola, J.R.8    Morris, L.9
  • 19
    • 33746763724 scopus 로고    scopus 로고
    • Aiming to induce broadly reactive neutralizing antibody responses with HIV-1 vaccine candidates
    • DOI 10.1586/14760584.5.4.579
    • Haynes, B. F., and D. C. Montefiori. 2006. Aiming to induce broadly reactive neutralizing antibody responses with HIV-1 vaccine candidates. Expert Rev. Vaccines 5:579-595. (Pubitemid 44627888)
    • (2006) Expert Review of Vaccines , vol.5 , Issue.4 , pp. 579-595
    • Haynes, B.F.1    Montefiori, D.C.2
  • 20
    • 35348926466 scopus 로고    scopus 로고
    • Amino acid conservation in the gp41 transmembrane protein and natural polymorphisms associated with enfuvirtide resistance across HIV-1 variants
    • Holguín, A., E. R. De Arellano, and V. Soriano. 2007. Amino acid conservation in the gp41 transmembrane protein and natural polymorphisms associated with enfuvirtide resistance across HIV-1 variants. AIDS Res. Hum. Retroviruses 23:1067-1074.
    • (2007) AIDS Res. Hum. Retroviruses , vol.23 , pp. 1067-1074
    • Holguín, A.1    De Arellano, E.R.2    Soriano, V.3
  • 21
    • 0035163480 scopus 로고    scopus 로고
    • Conserved, N-linked carbohydrates of human immunodeficiency virus type 1 gp41 are largely dispensable for viral replication
    • Johnson, W. E., J. M. Sauvron, and R. C. Desrosiers. 2001. Conserved, N-linked carbohydrates of human immunodeficiency virus type 1 gp41 are largely dispensable for viral replication. J. Virol. 75:11426-11436.
    • (2001) J. Virol. , vol.75 , pp. 11426-11436
    • Johnson, W.E.1    Sauvron, J.M.2    Desrosiers, R.C.3
  • 22
    • 0031962175 scopus 로고    scopus 로고
    • Conformational changes in cell surface HIV-1 envelope glycoproteins are triggered by cooperation between cell surface CD4 and co-receptors
    • Jones, P. L., T. Korte, and R. Blumenthal. 1998. Conformational changes in cell surface HIV-1 envelope glycoproteins are triggered by cooperation between cell surface CD4 and co-receptors. J. Biol. Chem. 273:404-409.
    • (1998) J. Biol. Chem. , vol.273 , pp. 404-409
    • Jones, P.L.1    Korte, T.2    Blumenthal, R.3
  • 24
    • 0028834461 scopus 로고
    • A trimeric structural domain of the HIV-1 transmembrane glycoprotein
    • Lu, M., S. C. Blacklow, and P. S. Kim. 1995. A trimeric structural domain of the HIV-1 transmembrane glycoprotein. Nat. Struct. Biol. 2:1075-1082.
    • (1995) Nat. Struct. Biol. , vol.2 , pp. 1075-1082
    • Lu, M.1    Blacklow, S.C.2    Kim, P.S.3
  • 25
    • 77649337650 scopus 로고    scopus 로고
    • Neutralizing antibodies induced by liposomal HIV-1 glycoprotein 41 peptide simultaneously bind to both the 2F5 or 4e10 epitope and lipid epitopes
    • Matyas, G. R., L. Wieczorek, Z. Beck, C. Ochsenbauer-Jambor, J. C. Kappes, N. L. Michael, V. R. Polonis, and C. R. Alving. 2009. Neutralizing antibodies induced by liposomal HIV-1 glycoprotein 41 peptide simultaneously bind to both the 2F5 or 4e10 epitope and lipid epitopes. AIDS 23:2069-2077.
    • (2009) AIDS , vol.23 , pp. 2069-2077
    • Matyas, G.R.1    Wieczorek, L.2    Beck, Z.3    Ochsenbauer-Jambor, C.4    Kappes, J.C.5    Michael, N.L.6    Polonis, V.R.7    Alving, C.R.8
  • 28
    • 7044231888 scopus 로고    scopus 로고
    • Conserved residues in the coiled-coil pocket of human immunodeficiency virus type 1 gp41 are essential for viral replication and interhelical interaction
    • Mo, H., A. K. Konstantinidis, K. D. Stewart, T. Dekhtyar, T. Ng, K. Swift, E. D. Matayoshi, W. Kati, W. Kohlbrenner, and A. Molla. 2004. Conserved residues in the coiled-coil pocket of human immunodeficiency virus type 1 gp41 are essential for viral replication and interhelical interaction. Virology 329:319-327.
    • (2004) Virology , vol.329 , pp. 319-327
    • Mo, H.1    Konstantinidis, A.K.2    Stewart, K.D.3    Dekhtyar, T.4    Ng, T.5    Swift, K.6    Matayoshi, E.D.7    Kati, W.8    Kohlbrenner, W.9    Molla, A.10
  • 29
    • 45849125030 scopus 로고    scopus 로고
    • Evaluating neutralizing antibodies against HIV, SIV, and SHIV in luciferase reporter gene assays
    • Unit 12.11. doi:10.1002/0471142735.im1211s64
    • Montefiori, D. 2005. Evaluating neutralizing antibodies against HIV, SIV, and SHIV in luciferase reporter gene assays. Curr. Protoc. Immunol. Unit 12.11. doi:10.1002/0471142735.im1211s64.
    • (2005) Curr. Protoc. Immunol.
    • Montefiori, D.1
  • 30
    • 40849136223 scopus 로고    scopus 로고
    • The membrane-proximal external region of the human immunodeficiency virus type 1 envelope: Dominant site of antibody neutralization and target for vaccine design
    • Montero, M., N. E. van Houten, X. Wang, and J. K. Scott. 2008. The membrane-proximal external region of the human immunodeficiency virus type 1 envelope: dominant site of antibody neutralization and target for vaccine design. Microbiol. Mol. Biol. Rev. 72:54-84.
    • (2008) Microbiol. Mol. Biol. Rev. , vol.72 , pp. 54-84
    • Montero, M.1    Van Houten, N.E.2    Wang, X.3    Scott, J.K.4
  • 31
    • 0025572710 scopus 로고
    • Dissociation of gp120 from HIV-1 virions induced by soluble CD4
    • Moore, J. P., J. A. McKeating, R. A. Weiss, and Q. J. Sattentau. 1990. Dissociation of gp120 from HIV-1 virions induced by soluble CD4. Science 250:1139-1142.
    • (1990) Science , vol.250 , pp. 1139-1142
    • Moore, J.P.1    McKeating, J.A.2    Weiss, R.A.3    Sattentau, Q.J.4
  • 32
    • 33750350280 scopus 로고    scopus 로고
    • A truncated alternative spliced isoform of human desmoglein 1 contains a specific T-cell epitope binding to the pemphigus foliaceus-associated HLA class II DR1*0102 molecule
    • Mouquet, H., S. Farci, P. Joly, B. Maillère, J. Leblond, L. Drouot, J. Leprince, M. C. Tonon, P. Loiseau, D. Charron, F. Tron, and D. Gilbert. 2006. A truncated alternative spliced isoform of human desmoglein 1 contains a specific T-cell epitope binding to the pemphigus foliaceus-associated HLA class II DR1*0102 molecule. J. Immunol. 177:6517-6526.
    • (2006) J. Immunol. , vol.177 , pp. 6517-6526
    • Mouquet, H.1    Farci, S.2    Joly, P.3    Maillère, B.4    Leblond, J.5    Drouot, L.6    Leprince, J.7    Tonon, M.C.8    Loiseau, P.9    Charron, D.10    Tron, F.11    Gilbert, D.12
  • 34
    • 0033942757 scopus 로고    scopus 로고
    • Conserved and exposed epitopes on intact, native, primary human immunodeficiency virus type 1 virions of group M
    • Nyambi, P. N., H. A. Mbah, S. Burda, C. Williams, M. K. Gorny, A. Nádas, and S. Zolla-Pazner. 2000. Conserved and exposed epitopes on intact, native, primary human immunodeficiency virus type 1 virions of group M. J. Virol. 74:7096-7107.
    • (2000) J. Virol. , vol.74 , pp. 7096-7107
    • Nyambi, P.N.1    Mbah, H.A.2    Burda, S.3    Williams, C.4    Gorny, M.K.5    Nádas, A.6    Zolla-Pazner, S.7
  • 36
    • 0025861673 scopus 로고
    • Two immunodominant domains of gp41 bind antibodies which enhance human immunodeficiency virus type 1 infection in vitro
    • Robinson, W. E. J., M. K. Gorny, J. Y. Xu, W. M. Mitchell, and S. Zolla-Pazner. 1991. Two immunodominant domains of gp41 bind antibodies which enhance human immunodeficiency virus type 1 infection in vitro. J. Virol. 65:4169-4176.
    • (1991) J. Virol. , vol.65 , pp. 4169-4176
    • Robinson, W.E.J.1    Gorny, M.K.2    Xu, J.Y.3    Mitchell, W.M.4    Zolla-Pazner, S.5
  • 38
    • 0032980413 scopus 로고    scopus 로고
    • A conserved tryptophan-rich motif in the membrane-proximal region of the human immunodeficiency virus type 1 gp41 ectodomain is important for Env- Mediated fusion and virus infectivity
    • Salzwedel, K., J. T. West, and E. Hunter. 1999. A conserved tryptophan-rich motif in the membrane-proximal region of the human immunodeficiency virus type 1 gp41 ectodomain is important for Env-mediated fusion and virus infectivity. J. Virol. 73:2469-2480. (Pubitemid 29098154)
    • (1999) Journal of Virology , vol.73 , Issue.3 , pp. 2469-2480
    • Salzwedel, K.1    West, J.T.2    Hunter, E.3
  • 40
    • 0025866185 scopus 로고
    • Conformational changes induced in the human immunodeficiency virus envelope glycoprotein by soluble CD4 binding
    • Sattentau, Q. J., and J. P. Moore. 1991. Conformational changes induced in the human immunodeficiency virus envelope glycoprotein by soluble CD4 binding. J. Exp. Med. 174:407-415.
    • (1991) J. Exp. Med. , vol.174 , pp. 407-415
    • Sattentau, Q.J.1    Moore, J.P.2
  • 41
    • 0028801450 scopus 로고
    • Epitope exposure on functional, oligomeric HIV-1 gp41 molecules
    • Sattentau, Q. J., S. Zolla-Pazner, and P. Poignard. 1995. Epitope exposure on functional, oligomeric HIV-1 gp41 molecules. Virology 206:713-717.
    • (1995) Virology , vol.206 , pp. 713-717
    • Sattentau, Q.J.1    Zolla-Pazner, S.2    Poignard, P.3
  • 42
    • 18244422922 scopus 로고    scopus 로고
    • The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of α1→2 mannose residues on the outer face of gp120
    • Scanlan, C. N., P. R., M. R. Wormald, E. O. Saphire, R. Stanfield, I. A. Wilson, H. Katinger, R. A. Dwek, P. M. Rudd, and D. R. Burton. 2002. The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of α1→2 mannose residues on the outer face of gp120. J. Virol. 76:7306-7321.
    • (2002) J. Virol. , vol.76 , pp. 7306-7321
    • Scanlan, C.N.1    R, P.2    Wormald, M.R.3    Saphire, E.O.4    Stanfield, R.5    Wilson, I.A.6    Katinger, H.7    Dwek, R.A.8    Rudd, P.M.9    Burton, D.R.10
  • 44
    • 37849000389 scopus 로고    scopus 로고
    • HIV-1 broadly neutralizing antibody extracts its epitope from a kinked gp41 ectodomain region on the viral membrane
    • Sun, Z. Y., K. J. Oh, M. Kim, J. Yu, V. Brusic, L. Song, Z. Qiao, J. H. Wang, G. Wagner, and E. L. Reinherz. 2008. HIV-1 broadly neutralizing antibody extracts its epitope from a kinked gp41 ectodomain region on the viral membrane. Immunity 28:52-63.
    • (2008) Immunity , vol.28 , pp. 52-63
    • Sun, Z.Y.1    Oh, K.J.2    Kim, M.3    Yu, J.4    Brusic, V.5    Song, L.6    Qiao, Z.7    Wang, J.H.8    Wagner, G.9    Reinherz, E.L.10
  • 45
    • 0025996335 scopus 로고
    • Role of conserved gp41 cysteine residues in the processing of human immunodeficiency virus envelope precursor and viral infectivity
    • Syu, W. J., W. R. Lee, B. Du, Q. C. Yu, M. Essex, and T. H. Lee. 1991. Role of conserved gp41 cysteine residues in the processing of human immunodeficiency virus envelope precursor and viral infectivity. J. Virol. 65:6349-6352.
    • (1991) J. Virol. , vol.65 , pp. 6349-6352
    • Syu, W.J.1    Lee, W.R.2    Du, B.3    Yu, Q.C.4    Essex, M.5    Lee, T.H.6
  • 46
    • 36849031722 scopus 로고    scopus 로고
    • Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning
    • DOI 10.1016/j.jim.2007.09.017, PII S0022175907003122
    • Tiller, T., E. Meffre, S. Yurasov, M. Tsuiji, M. C. Nussenzweig, and H. Wardemann. 2008. Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning. J. Immunol. Methods 329:112-124. (Pubitemid 350235462)
    • (2008) Journal of Immunological Methods , vol.329 , Issue.1-2 , pp. 112-124
    • Tiller, T.1    Meffre, E.2    Yurasov, S.3    Tsuiji, M.4    Nussenzweig, M.C.5    Wardemann, H.6
  • 47
    • 69549097604 scopus 로고    scopus 로고
    • HIV-1-specific antibody responses during acute and chronic HIV-1 infection
    • Tomaras, G. D., and B. F. Haynes. 2009. HIV-1-specific antibody responses during acute and chronic HIV-1 infection. Curr. Opin. HIV AIDS 4:373-379.
    • (2009) Curr. Opin. HIV AIDS , vol.4 , pp. 373-379
    • Tomaras, G.D.1    Haynes, B.F.2
  • 49
    • 0028865465 scopus 로고
    • Cross-clade neutralization of primary isolates of human immunodeficiency virus type 1 by human monoclonal antibodies and tetrameric CD4-IgG
    • Trkola, A., A. B. Pomales, H. Yuan, B. Korber, P. J. Maddon, G. P. Allaway, H. Katinge, C. F. Barbas, D. R Burton, D. D. Ho, et al. 1995. Cross-clade neutralization of primary isolates of human immunodeficiency virus type 1 by human monoclonal antibodies and tetrameric CD4-IgG. J. Virol. 69:6609-6617.
    • (1995) J. Virol. , vol.69 , pp. 6609-6617
    • Trkola, A.1    Pomales, A.B.2    Yuan, H.3    Korber, B.4    Maddon, P.J.5    Allaway, G.P.6    Katinge, H.7    Barbas, C.F.8    Burton, D.R.9    Ho, D.D.10
  • 52
    • 0030962291 scopus 로고    scopus 로고
    • Atomic structure of the ectodomain from HIV-1 gp41
    • DOI 10.1038/387426a0
    • Weissenhorn, W., A. Dessen, S. C. Harrison, J. J. Skehel, and D. C. Wiley. 1997. Atomic structure of the ectodomain from HIV-1 gp41. Nature 387:426-430. (Pubitemid 27227210)
    • (1997) Nature , vol.387 , Issue.6631 , pp. 426-430
    • Weissenhorn, W.1    Dessen, A.2    Harrison, S.C.3    Skehel, J.J.4    Wiley, D.C.5
  • 53
    • 0026055421 scopus 로고
    • Epitope mapping of two immunodominant domains of gp41, the transmembrane protein of human immunodeficiency virus type 1, using ten human monoclonal antibodies
    • Xu, J. Y., M. K. Gorny, T. Palker, S. Karwowska, and S. Zolla-Pazner. 1991. Epitope mapping of two immunodominant domains of gp41, the transmembrane protein of human immunodeficiency virus type 1, using ten human monoclonal antibodies. J. Virol. 65:4832-4838.
    • (1991) J. Virol. , vol.65 , pp. 4832-4838
    • Xu, J.Y.1    Gorny, M.K.2    Palker, T.3    Karwowska, S.4    Zolla-Pazner, S.5
  • 54
    • 0034087050 scopus 로고    scopus 로고
    • Characterization of stable, soluble trimers containing complete ectodomains of human immunodeficiency virus type 1 envelope glycoproteins
    • DOI 10.1128/JVI.74.12.5716-5725.2000
    • Yang, X., M. Farzan, R. Wyatt, and J. Sodroski. 2000. Characterization of stable, soluble trimers containing complete ectodomains of human immunodeficiency virus type 1 envelope glycoproteins. J. Virol. 74:5716-5725. (Pubitemid 30346608)
    • (2000) Journal of Virology , vol.74 , Issue.12 , pp. 5716-5725
    • Yang, X.1    Farzan, M.2    Wyatt, R.3    Sodroski, J.4
  • 55
    • 4544373403 scopus 로고    scopus 로고
    • Role of Hydrophobic Residues in the Central Ectodomain of gp41 in Maintaining the Association between Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Subunits gp120 and gp41
    • DOI 10.1128/JVI.78.9.4921-4926.2004
    • York, J., and J. H. Nunberg. 2004. Role of hydrophobic residues in the central ectodomain of gp41 in maintaining the association between human immunodeficiency virus type 1 envelope glycoprotein subunits gp120 and gp41. J. Virol. 78:4921-4926. (Pubitemid 38501114)
    • (2004) Journal of Virology , vol.78 , Issue.9 , pp. 4921-4926
    • York, J.1    Nunberg, J.H.2
  • 56
    • 33644752818 scopus 로고    scopus 로고
    • Simian immunodeficiency virus engrafted with human immunodeficiency virus type 1 (HIV-1)-specific epitopes: Replication, neutralization, and survey of HIV-1-positive plasma
    • Yuste, E., H. B. Sanford, J. Carmody, J. Bixby, S. Little, M. B. Zwick, T. Greenough, D. R. Burton, D. D. Richman, R. C. Desrosiers, and W. E. Johnson. 2006. Simian immunodeficiency virus engrafted with human immunodeficiency virus type 1 (HIV-1)-specific epitopes: replication, neutralization, and survey of HIV-1-positive plasma. J. Virol. 80:3030-3041.
    • (2006) J. Virol. , vol.80 , pp. 3030-3041
    • Yuste, E.1    Sanford, H.B.2    Carmody, J.3    Bixby, J.4    Little, S.5    Zwick, M.B.6    Greenough, T.7    Burton, D.R.8    Richman, D.D.9    Desrosiers, R.C.10    Johnson, W.E.11
  • 58
    • 58249100316 scopus 로고    scopus 로고
    • Cross-reactive HIV-1-neutralizing activity of serum IgG from a rabbit immunized with gp41 fused to IgG1 Fc: Possible role of the prolonged half-life of the immunogen
    • Zhang, M. Y., Y. Wang, M. K. Mankowski, R. G. Ptak, and D. S. Dimitrov. 2009. Cross-reactive HIV-1-neutralizing activity of serum IgG from a rabbit immunized with gp41 fused to IgG1 Fc: possible role of the prolonged half-life of the immunogen. Vaccine 27:857-863.
    • (2009) Vaccine , vol.27 , pp. 857-863
    • Zhang, M.Y.1    Wang, Y.2    Mankowski, M.K.3    Ptak, R.G.4    Dimitrov, D.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.