-
1
-
-
0038398622
-
The insulin-like growth factor system and cancer
-
LeRoith D, Roberts CT Jr. The insulin-like growth factor system and cancer. Cancer Lett 2003; 195: 127-137
-
(2003)
Cancer Lett
, vol.195
, pp. 127-137
-
-
Leroith, D.1
Roberts Jr., C.T.2
-
2
-
-
33846874575
-
The role of the IGF system in cancer growth and metastasis: Overview and recent insights
-
Samani AA, Yakar S, LeRoith D, Brodt P. The role of the IGF system in cancer growth and metastasis: overview and recent insights. Endocr Rev 2007; 28: 20-47
-
(2007)
Endocr Rev
, vol.28
, pp. 20-47
-
-
Samani, A.A.1
Yakar, S.2
Leroith, D.3
Brodt, P.4
-
3
-
-
0028997487
-
Insulin-like growth factor I overexpression in human pancreatic cancer: Evidence for autocrine and paracrine roles
-
Bergmann U, Funatomi H, Yokoyama M, Beger HG, Korc M. Insulin-like growth factor I overexpression in human pancreatic cancer: evidence for autocrine and paracrine roles. Cancer Res 1995; 55: 2007-2011
-
(1995)
Cancer Res
, vol.55
, pp. 2007-2011
-
-
Bergmann, U.1
Funatomi, H.2
Yokoyama, M.3
Beger, H.G.4
Korc, M.5
-
4
-
-
0036820322
-
Serum and tissue level of insulin-like growth factor-I (IGF-I) and IGF-I binding proteins as an index of pancreatitis and pancreatic cancer
-
Karna E, Surazynski A, Orłowski K, Łaszkiewicz J, Puchalski Z, Nawrat P, Pałka J. Serum and tissue level of insulin-like growth factor-I (IGF-I) and IGF-I binding proteins as an index of pancreatitis and pancreatic cancer. Int J Exp Pathol 2002; 83: 239-245
-
(2002)
Int J Exp Pathol
, vol.83
, pp. 239-245
-
-
Karna, E.1
Surazynski, A.2
Orłowski, K.3
Laszkiewicz, J.4
Puchalski, Z.5
Nawrat, P.6
Pałka, J.7
-
5
-
-
0042889104
-
Expression and distribution of insulin-like growth factor-1 receptor in human carcinomas
-
Ouban A, Muraca P, Yeatman T, Coppola D. Expression and distribution of insulin-like growth factor-1 receptor in human carcinomas. Hum Pathol 2003; 34: 803-808
-
(2003)
Hum Pathol
, vol.34
, pp. 803-808
-
-
Ouban, A.1
Muraca, P.2
Yeatman, T.3
Coppola, D.4
-
6
-
-
0042926509
-
Regulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and angiogenesis by an insulin-like growth factor-I receptor autocrine loop in human pancreatic cancer
-
Stoeltzing O, Liu W, Reinmuth N, Fan F, Parikh AA, Bucana CD, Evans DB, Semenza GL, Ellis LM. Regulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and angiogenesis by an insulin-like growth factor-I receptor autocrine loop in human pancreatic cancer. Am J Pathol 2003; 163: 1001-1011
-
(2003)
Am J Pathol
, vol.163
, pp. 1001-1011
-
-
Stoeltzing, O.1
Liu, W.2
Reinmuth, N.3
Fan, F.4
Parikh, A.A.5
Bucana, C.D.6
Evans, D.B.7
Semenza, G.L.8
Ellis, L.M.9
-
8
-
-
0032988428
-
Activation of MAP kinases in growth responsive pancreatic cancer cells
-
Douziech N, Calvo E, Lainé J, Morisset J. Activation of MAP kinases in growth responsive pancreatic cancer cells. Cell Signal 1999; 11: 591-602
-
(1999)
Cell Signal
, vol.11
, pp. 591-602
-
-
Douziech, N.1
Calvo, E.2
Lainé, J.3
Morisset, J.4
-
9
-
-
0035177036
-
Growth factors and their receptors in pancreatic cancer
-
Ozawa F, Friess H, Tempia-Caliera A, Kleeff J, Büchler MW. Growth factors and their receptors in pancreatic cancer. Teratog Carcinog Mutagen 2001; 21: 27-44
-
(2001)
Teratog Carcinog Mutagen
, vol.21
, pp. 27-44
-
-
Ozawa, F.1
Friess, H.2
Tempia-Caliera, A.3
Kleeff, J.4
Büchler, M.W.5
-
10
-
-
0034738796
-
Establishment of a new human pancreatic cancer cell line, NOR-P1, with high angiogenic activity and metastatic potential
-
Sato N, Mizumoto K, Beppu K, Maehara N, Kusumoto M, Nabae T, Morisaki T, Katano M, Tanaka M. Establishment of a new human pancreatic cancer cell line, NOR-P1, with high angiogenic activity and metastatic potential. Cancer Lett 2000; 155: 153-161
-
(2000)
Cancer Lett
, vol.155
, pp. 153-161
-
-
Sato, N.1
Mizumoto, K.2
Beppu, K.3
Maehara, N.4
Kusumoto, M.5
Nabae, T.6
Morisaki, T.7
Katano, M.8
Tanaka, M.9
-
11
-
-
33751001327
-
Signaling pathway of insulin-like growth factor-II as a target of molecular therapy for hepatoblastoma
-
Tomizawa M, Saisho H. Signaling pathway of insulin-like growth factor-II as a target of molecular therapy for hepatoblastoma. World J Gastroenterol 2006; 12: 6531-6535
-
(2006)
World J Gastroenterol
, vol.12
, pp. 6531-6535
-
-
Tomizawa, M.1
Saisho, H.2
-
12
-
-
0037112511
-
Reduced expression of insulin-like growth factor I receptors in MCF-7 breast cancer cells leads to a more metastatic phenotype
-
Pennisi PA, Barr V, Nunez NP, Stannard B, Le Roith D. Reduced expression of insulin-like growth factor I receptors in MCF-7 breast cancer cells leads to a more metastatic phenotype. Cancer Res 2002; 62: 6529-6537
-
(2002)
Cancer Res
, vol.62
, pp. 6529-6537
-
-
Pennisi, P.A.1
Barr, V.2
Nunez, N.P.3
Stannard, B.4
le Roith, D.5
-
13
-
-
0035857042
-
Aberrant expression and activation of insulin-like growth factor-1 receptor (IGF-1R) are mediated by an induction of IGF-1R promoter activity and stabilization of IGF-1R mRNA and contributes to growth factor independence and increased survival of the pancreatic cancer cell line MIA PaCa-2
-
Nair PN, De Armond DT, Adamo ML, Strodel WE, Freeman JW. Aberrant expression and activation of insulin-like growth factor-1 receptor (IGF-1R) are mediated by an induction of IGF-1R promoter activity and stabilization of IGF-1R mRNA and contributes to growth factor independence and increased survival of the pancreatic cancer cell line MIA PaCa-2. Oncogene 2001; 20: 8203-8214
-
(2001)
Oncogene
, vol.20
, pp. 8203-8214
-
-
Nair, P.N.1
de Armond, D.T.2
Adamo, M.L.3
Strodel, W.E.4
Freeman, J.W.5
-
14
-
-
58149241090
-
Enhanced therapeutic effects for human pancreatic cancer by application K-ras and IGF-IR antisense oligodeoxynucleotides
-
Shen YM, Yang XC, Yang C, Shen JK. Enhanced therapeutic effects for human pancreatic cancer by application K-ras and IGF-IR antisense oligodeoxynucleotides. World J Gastroenterol 2008; 14: 5176-5185
-
(2008)
World J Gastroenterol
, vol.14
, pp. 5176-5185
-
-
Shen, Y.M.1
Yang, X.C.2
Yang, C.3
Shen, J.K.4
-
15
-
-
46049100584
-
Inhibition of insulin-like growth factor-I receptor (IGF-IR) using NVP-AEW541, a small molecule kinase inhibitor, reduces orthotopic pancreatic cancer growth and angiogenesis
-
Moser C, Schachtschneider P, Lang SA, Gaumann A, Mori A, Zimmermann J, Schlitt HJ, Geissler EK, Stoeltzing O. Inhibition of insulin-like growth factor-I receptor (IGF-IR) using NVP-AEW541, a small molecule kinase inhibitor, reduces orthotopic pancreatic cancer growth and angiogenesis. Eur J Cancer 2008; 44: 1577-1586
-
(2008)
Eur J Cancer
, vol.44
, pp. 1577-1586
-
-
Moser, C.1
Schachtschneider, P.2
Lang, S.A.3
Gaumann, A.4
Mori, A.5
Zimmermann, J.6
Schlitt, H.J.7
Geissler, E.K.8
Stoeltzing, O.9
-
16
-
-
1642494838
-
Cyclolignans as inhibitors of the insulin-like growth factor-1 receptor and malignant cell growth
-
Girnita A, Girnita L, del Prete F, Bartolazzi A, Larsson O, Axelson M. Cyclolignans as inhibitors of the insulin-like growth factor-1 receptor and malignant cell growth. Cancer Res 2004; 64: 236-242
-
(2004)
Cancer Res
, vol.64
, pp. 236-242
-
-
Girnita, A.1
Girnita, L.2
del Prete, F.3
Bartolazzi, A.4
Larsson, O.5
Axelson, M.6
-
17
-
-
1842430485
-
Role of the phosphatidylinositol 3'-kinase-Akt signal pathway in the proliferation of human pancreatic ductal carcinoma cell lines
-
Takeda A, Osaki M, Adachi K, Honjo S, Ito H. Role of the phosphatidylinositol 3'-kinase-Akt signal pathway in the proliferation of human pancreatic ductal carcinoma cell lines. Pancreas 2004; 28: 353-358
-
(2004)
Pancreas
, vol.28
, pp. 353-358
-
-
Takeda, A.1
Osaki, M.2
Adachi, K.3
Honjo, S.4
Ito, H.5
-
18
-
-
0034618369
-
MEK/ERK signaling pathway regulates the expression of Bcl-2, Bcl-X(L), and Mcl-1 and promotes survival of human pancreatic cancer cells
-
Boucher MJ, Morisset J, Vachon PH, Reed JC, Lainé J, Rivard N. MEK/ERK signaling pathway regulates the expression of Bcl-2, Bcl-X(L), and Mcl-1 and promotes survival of human pancreatic cancer cells. J Cell Biochem 2000; 79: 355-369
-
(2000)
J Cell Biochem
, vol.79
, pp. 355-369
-
-
Boucher, M.J.1
Morisset, J.2
Vachon, P.H.3
Reed, J.C.4
Lainé, J.5
Rivard, N.6
-
19
-
-
0028793568
-
Increased tumorigenicity in the human pancreatic cell line MIA PaCa-2 is associated with an aberrant regulation of an IGF-1 autocrine loop and lack of expression of the TGF-beta type RII receptor
-
Freeman JW, Mattingly CA, Strodel WE. Increased tumorigenicity in the human pancreatic cell line MIA PaCa-2 is associated with an aberrant regulation of an IGF-1 autocrine loop and lack of expression of the TGF-beta type RII receptor. J Cell Physiol 1995; 165: 155-163
-
(1995)
J Cell Physiol
, vol.165
, pp. 155-163
-
-
Freeman, J.W.1
Mattingly, C.A.2
Strodel, W.E.3
-
20
-
-
19944372755
-
Inhibition of different intracellular signal cascades in human pancreatic cancer cells
-
Axelson J, Lindell M, Hörlin K, Ohlsson B. Inhibition of different intracellular signal cascades in human pancreatic cancer cells. Pancreatology 2005; 5: 251-258
-
(2005)
Pancreatology
, vol.5
, pp. 251-258
-
-
Axelson, J.1
Lindell, M.2
Hörlin, K.3
Ohlsson, B.4
-
21
-
-
0034817112
-
MEK/ERK-mediated proliferation is negatively regulated by P38 map kinase in the human pancreatic cancer cell line, PANC-1
-
Ding XZ, Adrian TE. MEK/ERK-mediated proliferation is negatively regulated by P38 map kinase in the human pancreatic cancer cell line, PANC-1. Biochem Biophys Res Commun 2001; 282: 447-453
-
(2001)
Biochem Biophys Res Commun
, vol.282
, pp. 447-453
-
-
Ding, X.Z.1
Adrian, T.E.2
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