Fragment C of tetanus toxin, more than a carrier. Novel perspectives in non-viral ALS gene therapy

Journal of Molecular Medicine

Volumn 88, Issue 3, 2010, Pages 297-308

  Moreno Igoa, María ^a   Calvo, Ana Cristina ^a   Penas, Clara ^b   Manzano, Raquel ^a   Oliván, Sara ^a   Muñoz, María Jesús ^a   Mancuso, Renzo ^b   Zaragoza, Pilar ^a   Aguilera, José ^c   Navarro, Xavier ^b   Osta Pinzolas, Rosario ^a  

^a UNIVERSITY OF ZARAGOZA   (Spain)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^c INSTITUT DE NEUROCIÈNCIES   (Spain)

Author keywords

Anti apoptotic signalling pathways; C fragment of tetanus toxin; Motor neuron pathology; Neurodegenerative mouse model; Non viral gene therapy

Indexed keywords

CARBOXY TERMINAL FRAGMENT TETANUS TOXIN HEAVY CHAIN; CASPASE 3; COPPER ZINC SUPEROXIDE DISMUTASE; INTERLEUKIN 1BETA CONVERTING ENZYME; NAKED DNA; PROTEIN KINASE B; TETANUS ANTIBODY; UNCLASSIFIED DRUG; VIRUS VECTOR;

AMINO ACID SUBSTITUTION; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL SURVIVAL; CONTROLLED STUDY; DEGENERATIVE DISEASE; DOWN REGULATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; EXPRESSION VECTOR; GENE EXPRESSION; GENETIC VARIABILITY; MOTONEURON; MOUSE; MUSCLE INNERVATION; NEUROMUSCULAR FUNCTION; NONHUMAN; NONVIRAL GENE THERAPY; NUCLEOTIDE SEQUENCE; SIGNAL TRANSDUCTION; SPINAL CORD NERVE CELL; TRANSGENIC MOUSE; VIRAL GENE DELIVERY SYSTEM; WESTERN BLOTTING;

EID: 77951256302     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00109-009-0556-y     Document Type: Article

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