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Volumn 7, Issue 2, 2010, Pages 107-113

Cachexia - An intrinsic factor in wound healing

Author keywords

Cachexia; Collagen deposition; Inflammation; Reepithelialisation; Wound healing

Indexed keywords

COLLAGEN; GELATINASE A; INTERLEUKIN 6; NITRIC OXIDE SYNTHASE; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

EID: 77951217905     PISSN: 17424801     EISSN: 1742481X     Source Type: Journal    
DOI: 10.1111/j.1742-481X.2010.00663.x     Document Type: Review
Times cited : (12)

References (55)
  • 2
    • 0027155669 scopus 로고
    • Chronic wounds: Pathophysiologic and experimental considerations
    • Falanga V. Chronic wounds: pathophysiologic and experimental considerations. J Invest Dermatol 1993 100 : 721 725. (Pubitemid 23128373)
    • (1993) Journal of Investigative Dermatology , vol.100 , Issue.5 , pp. 721-725
    • Falanga, V.1
  • 3
    • 33744898953 scopus 로고    scopus 로고
    • Pathophysiology of wound healing
    • Halloran CM, Slavin JP. Pathophysiology of wound healing. Surgery 2002 20 : i v.
    • (2002) Surgery , vol.20
    • Halloran, C.M.1    Slavin, J.P.2
  • 4
  • 7
    • 33845287214 scopus 로고    scopus 로고
    • Basic science of wound healing
    • Enoch S, Leaper DJ. Basic science of wound healing. Surgery 2005 23 : 37 42. (Pubitemid 40435388)
    • (2005) Surgery , vol.23 , Issue.2 , pp. 37-42
    • Enoch, S.1    Leaper, D.J.2
  • 8
    • 0036598961 scopus 로고    scopus 로고
    • Inflammation. 1: Its role in the healing of acute wounds.
    • Hart J. Inflammation. 1: its role in the healing of acute wounds. J Wound Care 2002 11 : 205 209.
    • (2002) J Wound Care , vol.11 , pp. 205-209
    • Hart, J.1
  • 10
    • 77951245748 scopus 로고    scopus 로고
    • NCBI. [online]. Entrez Gene. 13 August 2009. Available at. [accessed on 16 August 2009]
    • NCBI IL6 interleukin 6 (interferon, beta 2) [Homo sapiens] [online]. Entrez Gene. 13 August 2009. Available at: http://www.ncbi.nlm.nih.gov/sites/ entrez?Db=gene&Cmd=retrieve&dopt=full-report&list-uids= 3569&log$=genesensor4&logdbfrom=pubmed [accessed on 16 August 2009].
    • IL6 Interleukin 6 (Interferon, Beta 2) [Homo Sapiens]
  • 12
    • 34447104560 scopus 로고    scopus 로고
    • Interleukin-6 (IL-6) modulates migration and matrix metalloproteinase function in dermal fibroblasts from IL-6KO mice
    • Luckett LR, Gallucci RM. Interleukin-6 (IL-6) modulates migration and matrix metalloproteinase function in dermal fibroblasts from IL-6KO mice. Br J Dermatol 2007 156 : 1163 1171.
    • (2007) Br J Dermatol , vol.156 , pp. 1163-1171
    • Luckett, L.R.1    Gallucci, R.M.2
  • 14
    • 0036833427 scopus 로고    scopus 로고
    • Early postoperative compensatory anti-inflammatory response syndrome is associated with septic complications after major surgical trauma in patients with cancer
    • Mokart D, Capo C, Blache JL, Delpero JR, Houvenaeghel G, Martin C, Mege JL. Early postoperative compensatory anti-inflammatory response syndrome is associated with septic complications after major surgical trauma in patients with cancer. Br J Surg 2002 89 : 1450 1456.
    • (2002) Br J Surg , vol.89 , pp. 1450-1456
    • Mokart, D.1    Capo, C.2    Blache, J.L.3    Delpero, J.R.4    Houvenaeghel, G.5    Martin, C.6    Mege, J.L.7
  • 15
    • 33847691159 scopus 로고    scopus 로고
    • Study on the relationship of APACHE III and levels of cytokines in patients with systemic inflammatory response syndrome after coronary artery bypass grafting
    • DOI 10.1248/bpb.30.410
    • Mei YQ, Ji Q, Liu H, Wang X, Feng J, Long C, Cheng B, Xing Y, Li J, Hu D. Study on the relationship of APACHE III and levels of cytokines in patients with systemic inflammatory response syndrome after coronary artery bypass grafting. Biol Pharm Bull 2007 30 : 410 414. (Pubitemid 46355912)
    • (2007) Biological and Pharmaceutical Bulletin , vol.30 , Issue.3 , pp. 410-414
    • Mei, Y.Q.1    Ji, Q.2    Liu, H.3    Wang, X.4    Feng, J.5    Long, C.6    Cheng, B.7    Xing, Y.8    Li, J.9    Hu, D.10
  • 16
    • 0030945563 scopus 로고    scopus 로고
    • Wound healing and wound infection. What surgeons and anesthesiologists can do.
    • Hunt TK, Hopf HW. Wound healing and wound infection. What surgeons and anesthesiologists can do. Surg Clin North Am 1997 77 : 587 606.
    • (1997) Surg Clin North Am , vol.77 , pp. 587-606
    • Hunt, T.K.1    Hopf, H.W.2
  • 18
    • 3042794583 scopus 로고    scopus 로고
    • Adiponectin and the systemic inflammatory response in weight-losing patients with non-small cell lung cancer
    • Jamieson NB, Brown DJ, Michael Wallace A, McMillan DC. Adiponectin and the systemic inflammatory response in weight-losing patients with non-small cell lung cancer. Cytokine 2004 27 : 90 2.
    • (2004) Cytokine , vol.27 , pp. 90-2
    • Jamieson, N.B.1    Brown, D.J.2    Michael Wallace, A.3    McMillan, D.C.4
  • 19
    • 36348976492 scopus 로고    scopus 로고
    • Impact of weight loss on circulating IL-1, IL-6, IL-8, TNF-α, VEGF-A, VEGF-C and midkine in gastroesophageal cancer patients
    • DOI 10.1016/j.clinbiochem.2007.07.013, PII S0009912007002986
    • Krzystek-Korpacka M, Matusiewicz M, Diakowska D, Grabowski K, Blachut K, Kustrzeba-Wojcicka I, Banas T. Impact of weight loss on circulating IL-1, IL-6, IL-8, TNF-alpha, VEGF-A, VEGF-C and midkine in gastroesophageal cancer patients. Clin Biochem 2007 40 : 1353 1360. (Pubitemid 350151421)
    • (2007) Clinical Biochemistry , vol.40 , Issue.18 , pp. 1353-1360
    • Krzystek-Korpacka, M.1    Matusiewicz, M.2    Diakowska, D.3    Grabowski, K.4    Blachut, K.5    Kustrzeba-Wojcicka, I.6    Banas, T.7
  • 21
    • 52949109129 scopus 로고    scopus 로고
    • Fibrinogen synthesis is increased in cachectic patients with chronic heart failure
    • Witte KK, Ford SJ, Preston T, Parker JD, Clark AL. Fibrinogen synthesis is increased in cachectic patients with chronic heart failure. Int J Cardiol 2008 129 : 363 367.
    • (2008) Int J Cardiol , vol.129 , pp. 363-367
    • Witte, K.K.1    Ford, S.J.2    Preston, T.3    Parker, J.D.4    Clark, A.L.5
  • 23
    • 49749135154 scopus 로고    scopus 로고
    • Cachexia and neuropeptide y
    • Morley JE, Farr SA. Cachexia and neuropeptide Y. Nutrition 2008 24 : 815 819.
    • (2008) Nutrition , vol.24 , pp. 815-819
    • Morley, J.E.1    Farr, S.A.2
  • 26
    • 34548564150 scopus 로고    scopus 로고
    • Skin wound healing in the SKH-1 female mouse following inducible nitric oxide synthase inhibition
    • Bell RR, Dunstan RW, Khan NK. Skin wound healing in the SKH-1 female mouse following inducible nitric oxide synthase inhibition. Br J Dermatol 2007 157 : 656 661.
    • (2007) Br J Dermatol , vol.157 , pp. 656-661
    • Bell, R.R.1    Dunstan, R.W.2    Khan, N.K.3
  • 28
    • 37549031652 scopus 로고    scopus 로고
    • Persistent epithelial defects due to neurotrophic keratopathy treated with a substance P-derived peptide and insulin-like growth factor 1
    • Nishida T, Chikama T, Morishige N, Yanai R, Yamada N, Saito J. Persistent epithelial defects due to neurotrophic keratopathy treated with a substance P-derived peptide and insulin-like growth factor 1. Jpn J Ophthalmol 2007 51 : 442 447.
    • (2007) Jpn J Ophthalmol , vol.51 , pp. 442-447
    • Nishida, T.1    Chikama, T.2    Morishige, N.3    Yanai, R.4    Yamada, N.5    Saito, J.6
  • 29
    • 47149099393 scopus 로고    scopus 로고
    • Estrogen, not intrinsic aging, is the major regulator of delayed human wound healing in the elderly
    • [Online] Available at. [Accessed on 29 April 2009]
    • Hardman MJ, Ashcroft GS. Estrogen, not intrinsic aging, is the major regulator of delayed human wound healing in the elderly. Genome Biology 2008 9 : R80 [Online] Available at: http://www.pubmedcentral.nih.gov/articlerender.fcgi? artid=2441466 [Accessed on 29 April 2009].
    • (2008) Genome Biology , vol.9 , pp. 80
    • Hardman, M.J.1    Ashcroft, G.S.2
  • 30
    • 21844436308 scopus 로고    scopus 로고
    • Megestrol acetate for the treatment of anorexia-cachexia syndrome
    • Berenstein EG, Ortiz Z. Megestrol acetate for the treatment of anorexia-cachexia syndrome. Cochrane Database Syst Rev 2005 2 : CD004310.
    • (2005) Cochrane Database Syst Rev , vol.2 , pp. 004310
    • Berenstein, E.G.1    Ortiz, Z.2
  • 31
    • 0029921173 scopus 로고    scopus 로고
    • Muscle wasting and dedifferentiation induced by oxidative stress in a murine model of cachexia is prevented by inhibitors of nitric oxide synthesis and antioxidants
    • Buck M, Chojkier M. Muscle wasting and dedifferentiation induced by oxidative stress in a murine model of cachexia is prevented by inhibitors of nitric oxide synthesis and antioxidants. EMBO J 1996 15 : 1753 1765. (Pubitemid 26119211)
    • (1996) EMBO Journal , vol.15 , Issue.8 , pp. 1753-1765
    • Buck, M.1    Chojkier, M.2
  • 32
    • 17044432198 scopus 로고    scopus 로고
    • NOS isoenzyme content in brain nuclei as related to food intake in experimental cancer cachexia
    • DOI 10.1016/j.molbrainres.2004.10.038
    • Wang W, Svanberg E, Delbro D, Lundholm K. NOS isoenzyme content in brain nuclei as related to food intake in experimental cancer cachexia. Brain Res Mol Brain Res 2005 134 : 205 214. (Pubitemid 40504137)
    • (2005) Molecular Brain Research , vol.134 , Issue.2 , pp. 205-214
    • Wang, W.1    Svanberg, E.2    Delbro, D.3    Lundholm, K.4
  • 33
    • 54049126864 scopus 로고    scopus 로고
    • The 3R principle and the use of non-human primates in the study of neurodegenerative diseases: The case of Parkinson's disease
    • Vitale A, Manciocco A, Alleva E. The 3R principle and the use of non-human primates in the study of neurodegenerative diseases: the case of Parkinson's disease. Neurosci Biobehav Rev 2009 33 : 33 47.
    • (2009) Neurosci Biobehav Rev , vol.33 , pp. 33-47
    • Vitale, A.1    Manciocco, A.2    Alleva, E.3
  • 34
    • 0022371461 scopus 로고
    • Identity of tumour necrosis factor and the macrophage-secreted factor cachectin
    • DOI 10.1038/316552a0
    • Beutler B, Greenwald D, Hulmes JD, Chang M, Pan YC, Mathison J, Ulevitch R, Cerami A. Identity of tumour necrosis factor and the macrophage-secreted factor cachectin. Nature 1985 316 : 552 554. (Pubitemid 16239366)
    • (1985) Nature , vol.316 , Issue.6028 , pp. 552-554
    • Beutler, B.1    Greenwald, D.2    Hulmes, J.D.3
  • 35
    • 0025152119 scopus 로고
    • Tumor necrosis factor-α and interferon-α suppress the activation of human type I collagen gene expression by transforming growth factor-β1. Evidence for two distinct mechanisms of inhibition at the transcriptional and posttranscriptional levels
    • Kähäri VM, Chen YQ, Su MW, Ramirez F, Uitto J. Tumor necrosis factor-α and interferon-γ suppress the activation of human type I collagen gene expression by transforming growth factor-β1. Evidence for two distinct mechanisms of inhibition at the transcriptional and posttranscriptional levels. J Clin Invest 1990 86 : 1489 1495. (Pubitemid 20372595)
    • (1990) Journal of Clinical Investigation , vol.86 , Issue.5 , pp. 1489-1495
    • Kahari, V.-M.1    Chen, Y.Q.2    Su, M.W.3    Ramirez, F.4    Uitto, J.5
  • 37
    • 0021087552 scopus 로고
    • Specifically decreased collagen biosynthesis in scurvy dissociated from an effect on proline hydroxylation and correlated with body weight loss. In vitro studies in guinea pig calvarial bones
    • Chojkier M, Spanheimer R, Peterkofsky B. Specifically decreased collagen biosynthesis in scurvy dissociated from an effect on proline hydroxylation and correlated with body weight loss. In vitro studies in guinea pig calvarial bones. J Clin Invest 1983 72 : 826 835. (Pubitemid 14211392)
    • (1983) Journal of Clinical Investigation , vol.72 , Issue.3 , pp. 826-835
    • Chojkier, M.1    Spanheimer, R.2    Peterkofsky, B.3
  • 39
    • 0030011283 scopus 로고    scopus 로고
    • Tumor necrosis factor-α inhibits collagen α1(I) gene expression and wound healing in a murine model of cachexia
    • Buck M, Houglum K, Chojkier M. Tumour necrosis factor-α inhibits collagen α1(I) gene expression and wound healing in a murine model of cachexia. Am J Pathol 1996 149 : 195 204. (Pubitemid 26230991)
    • (1996) American Journal of Pathology , vol.149 , Issue.1 , pp. 195-204
    • Buck, M.1    Houglum, K.2    Chojkier, M.3
  • 40
    • 33747609329 scopus 로고    scopus 로고
    • Etanercept decreases tumor necrosis factor-α activity in chronic wound fluid
    • DOI 10.1111/j.1743-6109.2006.00141.x
    • Cowin AJ, Hatzirodos N, Rigden J, Fitridge R, Belford DA. Etanercept decreases tumor necrosis factor-α activity in chronic wound fluid. Wound Repair Regen 2006 14 : 421 426. (Pubitemid 44266598)
    • (2006) Wound Repair and Regeneration , vol.14 , Issue.4 , pp. 421-426
    • Cowin, A.J.1    Hatzirodos, N.2    Rigden, J.3    Fitridge, R.4    Belford, D.A.5
  • 41
    • 3543047947 scopus 로고    scopus 로고
    • Effects of tumor necrosis factor-α (TNFα) in epidermal keratinocytes revealed using global transcriptional profiling
    • DOI 10.1074/jbc.M400642200
    • Banno T, Gazel A, Blumenberg M. Effects of tumor necrosis factor-α (TNF-α) in epidermal keratinocytes revealed using global transcriptional profiling. J Biol Chem 2004 279 : 32633 32642. (Pubitemid 39014721)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.31 , pp. 32633-32642
    • Banno, T.1    Gazel, A.2    Blumenberg, M.3
  • 42
    • 34447134805 scopus 로고    scopus 로고
    • Safety of etanercept therapy in rheumatoid patients undergoing surgery: Preliminary report
    • DOI 10.1007/s10067-007-0534-0
    • Corrao S, Pistone G, Arnone S, Calvo L, Scaglione R, Licata G. Safety of etanercept therapy in rheumatoid patients undergoing surgery: preliminary report. Clin Rheumatol 2007 26 : 1513 1515. (Pubitemid 47193569)
    • (2007) Clinical Rheumatology , vol.26 , Issue.9 , pp. 1513-1515
    • Corrao, S.1    Pistone, G.2    Arnone, S.3    Calvo, L.4    Scaglione, R.5    Licata, G.6
  • 43
    • 0030786935 scopus 로고    scopus 로고
    • How to read a paper: Getting your bearings (deciding what the paper is about)
    • Greenhalgh T. How to read a paper. Getting your bearings (deciding what the paper is about). BMJ 1997 315 : 243 246. (Pubitemid 27326334)
    • (1997) British Medical Journal , vol.315 , Issue.7102 , pp. 243-246
    • Greenhalgh, T.1
  • 45
    • 33845491244 scopus 로고    scopus 로고
    • Randomized phase 2 trial of anti-tumor necrosis factor therapy for cachexia in patients with early rheumatoid arthritis
    • Marcora SM, Chester KR, Mittal G, Lemmey AB, Maddison PJ. Randomized phase 2 trial of anti-tumor necrosis factor therapy for cachexia in patients with early rheumatoid arthritis. Am J Clin Nutr 2006 84 : 1463 1472. (Pubitemid 44912832)
    • (2006) American Journal of Clinical Nutrition , vol.84 , Issue.6 , pp. 1463-1472
    • Marcora, S.M.1    Chester, K.R.2    Mittal, G.3    Lemmey, A.B.4    Maddison, P.J.5
  • 46
    • 43449104499 scopus 로고    scopus 로고
    • Cancer cachexia: Developing multimodal therapy for a multidimensional problem
    • Fearon KC. Cancer cachexia: developing multimodal therapy for a multidimensional problem. Eur J Cancer 2008 44 : 1124 1132.
    • (2008) Eur J Cancer , vol.44 , pp. 1124-1132
    • Fearon, K.C.1
  • 47
    • 33847676783 scopus 로고    scopus 로고
    • Fibroblasts and myofibroblasts: Their source, function and role in disease
    • McAnulty RJ. Fibroblasts and myofibroblasts: their source, function and role in disease. Int J Biochem Cell Biol 2007 39 : 666 671.
    • (2007) Int J Biochem Cell Biol , vol.39 , pp. 666-671
    • McAnulty, R.J.1
  • 48
    • 13544259736 scopus 로고    scopus 로고
    • Cellular and molecular facets of keratinocyte reepithelization during wound healing
    • DOI 10.1016/j.yexcr.2004.10.033
    • Santoro MM, Gaudino G. Cellular and molecular facets of keratinocyte reepithelization during wound healing. Exp Cell Res 2005 304 : 274 286. (Pubitemid 40222094)
    • (2005) Experimental Cell Research , vol.304 , Issue.1 , pp. 274-286
    • Santoro, M.M.1    Gaudino, G.2
  • 49
    • 13944271697 scopus 로고    scopus 로고
    • Antagonists of activin signalling: Mechanisms and potential biological applications
    • Harrison CA, Gray PC, Vale WW, Robertson DM. Antagonists of activin signalling: mechanisms and potential biological applications. Trends Endocrinol Metab 2005 16 : 73 8.
    • (2005) Trends Endocrinol Metab , vol.16 , pp. 73-8
    • Harrison, C.A.1    Gray, P.C.2    Vale, W.W.3    Robertson, D.M.4
  • 50
    • 0342902626 scopus 로고    scopus 로고
    • Strong induction of activin expression after injury suggests an important role of activin in wound repair
    • DOI 10.1006/dbio.1996.0042
    • Hubner G, Hu Q, Smola H, Werner S. Strong induction of activin expression after injury suggests an important role of activin in wound repair. Dev Biol 1996 173 : 490 498. (Pubitemid 26064869)
    • (1996) Developmental Biology , vol.173 , Issue.2 , pp. 490-498
    • Hubner, G.1    Qianjin, H.2    Smola, H.3    Werner, S.4
  • 51
    • 0033214191 scopus 로고    scopus 로고
    • Overexpression of activin A in the skin of transgenic mice reveals new activities of activin in epidermal morphogenesis, dermal fibrosis and wound repair
    • DOI 10.1093/emboj/18.19.5205
    • Munz B, Smola H, Engelhardt F, Bleuel K, Brauchle M, Lein I, Evans LW, Huylebroeck D, Balling R, Werne S. Overexpression of activin A in the skin of transgenic mice reveals new activities of activin in epidermal morphogenesis, dermal fibrosis and wound repair. EMBO J 1999 18 : 5205 5215. (Pubitemid 29465571)
    • (1999) EMBO Journal , vol.18 , Issue.19 , pp. 5205-5215
    • Munz, B.1    Smola, H.2    Engelhardt, F.3    Bleuel, K.4    Brauchle, M.5    Lein, I.6    Evans, L.W.7    Huylebroeck, D.8    Balling, R.9    Werner, S.10
  • 52
    • 0035477312 scopus 로고    scopus 로고
    • Impaired wound healing in transgenic mice overexpressing the activin antagonist follistatin in the epidermis
    • DOI 10.1093/emboj/20.19.5361
    • Wankell M, Munz B, Hubner G, Hans W, Wolf E, Goppelt A, Werner S. Impaired would healing in transgenic mice overexpressing the activin antagonist follistatin in the epidermis. EMBO J 2001 20 : 5361 5372. (Pubitemid 32959456)
    • (2001) EMBO Journal , vol.20 , Issue.19 , pp. 5361-5372
    • Wankell, M.1    Munz, B.2    Hubner, G.3    Hans, W.4    Wolf, E.5    Goppelt, A.6    Werner, S.7
  • 54
    • 34548388339 scopus 로고    scopus 로고
    • Prevention of cachexia-like syndrome development and reduction of tumor progression in inhibin-deficient mice following administration of a chimeric activin receptor type II-murine Fc protein
    • DOI 10.1093/molehr/gam055
    • Li Q, Kumar R, Underwood K, O'Connor AE, Loveland KL, Seehra JS, Matzuk MM. Prevention of cachexia-like syndrome development and reduction of tumor progression in inhibin-deficient mice following administration of a chimeric activin receptor type II-murine Fc protein. Mol Hum Reprod 2007 13 : 675 683. (Pubitemid 47354915)
    • (2007) Molecular Human Reproduction , vol.13 , Issue.9 , pp. 675-683
    • Li, Q.1    Kumar, R.2    Underwood, K.3    O'Connor, A.E.4    Loveland, K.L.5    Seehra, J.S.6    Matzuk, M.M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.