Developmental silencing of human ζ-globin gene expression is mediated by the transcriptional repressor RREB1

Journal of Biological Chemistry

Volumn 285, Issue 14, 2010, Pages 10189-10197

  Chen, Ruei Lin ^a,b   Chou, Yu Chi ^b   Lan, Yii Jenq ^c,d   Huang, Ting Shuo ^c,d   Shen, C K James ^a,b  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b INSTITUTE OF MOLECULAR BIOLOGY   (Taiwan)

^c CHANG GUNG UNIVERSITY   (Taiwan)

^d CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

COOPERATIVE WORKS; EMBRYONIC STAGES; ERYTHROID CELLS; GLOBIN GENE; HEMOGLOBINOPATHIES; K562 CELLS; PROMOTER ACTIVITIES; PROTEIN-BINDING MOTIFS; PROTEIN-PROTEIN COMPLEXES; RNA INTERFERENCE; SITE DIRECTED MUTAGENESIS; TRANSCRIPTIONAL REPRESSORS; TRANSGENIC MICE; UP-REGULATION; ZINC FINGER;

CELL CULTURE; FUNCTIONAL POLYMERS; HEMOGLOBIN; HYDRAULIC STRUCTURES; MAMMALS; RNA; TRANSCRIPTION; ZINC;

GENE EXPRESSION REGULATION;

TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR ZF2; UNCLASSIFIED DRUG; ZETA GLOBIN; ZINC FINGER PROTEIN; ZINC FINGER PROTEIN RREB1;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL CULTURE; CONTROLLED STUDY; ERYTHROID CELL; GEL MOBILITY SHIFT ASSAY; GENE REPRESSION; GENE SILENCING; GENETIC TRANSCRIPTION; GENOTYPE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN MOTIF; RNA INTERFERENCE; SITE DIRECTED MUTAGENESIS;

ANIMALS; BASE SEQUENCE; BINDING SITES; BLOTTING, WESTERN; CHROMATIN IMMUNOPRECIPITATION; DNA-BINDING PROTEINS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE SILENCING; HUMANS; K562 CELLS; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROMOTER REGIONS, GENETIC; REGULATORY SEQUENCES, NUCLEIC ACID; REPRESSOR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; TRANSCRIPTION FACTORS; ZETA-GLOBINS;

MAMMALIA; MUS MUSCULUS;

EID: 77951210677     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.049130     Document Type: Article

References (44)

1. Stamatoyannopoulos, G., and Grosveld, F. (2001) in The Molecular Basis of Blood Diseases (Stamatoyannopoulos, G., Majerus, P., Perlmutter, R., and Varmus, H. eds) 3rd Ed., W. B. Saunders, Philadelphia
2. Tanimoto, K., and Engel, J. D. (2000) Trends Cardiovasc. Med. 10, 15-19
3. Palstra, R. J., de Laat, W., and Grosveld, F. (2008) Adv. Genet. 61, 107-142
4. Higgs, D. R., Vernimmen, D., and Wood, B. (2008) Adv. Genet. 61, 143-173
5. Orkin, S. H. (1992) Blood 80, 575-581
6. Kobayashi, M., and Yamamoto, M. (2007) J. Biochem. 142, 1-10
7. Bulger, M., Sawado, T., Schübeler, D., and Groudine, M. (2002) Curr. Opin. Genet. Dev. 12, 170-177
8. Shyu, Y. C., Lee, T. L., Ting, C. Y., Wen, S. C., Hsieh, L. J., Li, Y. C., Hwang, J. L., Lin, C. C., and Shen, C. K. (2005) Mol. Cell Biol. 25, 10365-10378
9. Bieker, J. J. (2005) Mt. Sinai J. Med. 72, 333-338
10. Shyu, Y. C., Lee, T. L., Wen, S. C., Chen, H., Hsiao, W. Y., Chen, X., Hwang, J., and Shen, C. K. (2007) Mol. Cell Biol. 27, 2309-2323
11. Raich, N., Clegg, C. H., Grofti, J., Roméo, P. H., and Stamatoyannopoulos, G. (1995) EMBO J. 14, 801-809
12. Tanabe, O., McPhee, D., Kobayashi, S., Shen, Y., Brandt, W., Jiang, X., Campbell, A. D., Chen, Y. T., Chang, C., Yamamoto, M., Tanimoto, K., and Engel, J. D. (2007) EMBO J. 26, 2295-2306
13. Zhou, W., Clouston, D. R., Wang, X., Cerruti, L., Cunningham, J. M., and Jane, S. M. (2000) Mol. Cell Biol. 20, 7662-7672
14. Sankaran, V. G., Menne, T. F., Xu, J., Akie, T. E., Lettre, G., Van Handel, B., Mikkola, H. K., Hirschhorn, J. N., Cantor, A. B., and Orkin, S. H. (2008) Science 322, 1839-1842
15. Gong, Q. H., Stern, J., and Dean, A. (1991) Mol. Cell Biol. 11, 2558-2566
16. Li, Q., Clegg, C., Peterson, K., Shaw, S., Raich, N., and Stamatoyannopoulos, G. (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 2444-2448
17. Tanabe, O., Katsuoka, F., Campbell, A. D., Song, W., Yamamoto, M., Tanimoto, K., and Engel, J. D. (2002) EMBO J. 21, 3434-3442
18. Zhao, Q., Zhou, W., Rank, G., Sutton, R., Wang, X., Cumming, H., Cerruti, L., Cunningham, J. M., and Jane, S. M. (2006) Blood 107, 2138-2145
19. Chen, Z., Luo, H. Y., Steinberg, M. H., and Chui, D. H. (2009) Blood Cells Mol. Dis. 42, 144-149
20. Higgs, D. R., Wood, W. G., Jarman, A. P., Sharpe, J., Lida, J., Pretorius, I. M., and Ayyub, H. (1990) Genes Dev. 4, 1588-1601
21. Zhang, Q., Reddy, P. M., Yu, C. Y., Bastiani, C., Higgs, D., Stamatoyannopoulos, G., Papayannopoulou, T., and Shen, C. K. (1993) Mol. Cell. Biol. 13, 2298-2308
22. Strauss, E. C., Andrews, N. C., Higgs, D. R., and Orkin, S. H. (1992) Mol. Cell. Biol. 12, 2135-2142
23. Huang, B. L., Fan-Chiang, I. R., Wen, S. C., Koo, H. C., Kao, W. Y., Gavva, N. R., and Shen, C. K. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 14669-14674
24. Yu, C. Y., Chen, J., Lin, L. I., Tam, M., and Shen, C. K. (1990) Mol. Cell. Biol. 10, 282-294
25. Zhang, Q., Rombel, I., Reddy, G., and Shen, C. K. (1995) in Molecular Biology of Hemoglobin Switch (Stamatoyannopoulos, G., ed) Intercept Ltd., Andover, UK
26. Stein, B., Rahmsdorf, H. J., Steffen, A., Litfin, M., and Herrlich, P. (1989) Mol. Cell. Biol. 9, 5169-5181
27. Wen, S. C., Roder, K., Hu, K. Y., Rombel, I., Gavva, N. R., Daftari, P., Kuo, Y. Y., Wang, C., and Shen, C. K. (2000) Mol. Cell. Biol. 20, 1993-2003
28. Moffat, J., Grueneberg, D. A., Yang, X., Kim, S. Y., Kloepfer, A. M., Hinkle, G., Piqani, B., Eisenhaure, T. M., Luo, B., Grenier, J. K., Carpenter, A. E., Foo, S. Y., Stewart, S. A., Stockwell, B. R., Hacohen, N., Hahn, W. C., Lander, E. S., Sabatini, D. M., and Root, D. E. (2006) Cell 124, 1283-1298
29. Fibach, E., and Prus, E. (2005) Current Protocols 69, 22F.7.1-22F.7.2
30. Wall, L., deBoer, E., and Grosveld, F. (1988) Genes Dev. 2, 1089-1100
31. Thiagalingam, A., De Bustros, A., Borges, M., Jasti, R., Compton, D., Diamond, L., Mabry, M., Ball, D. W., Baylin, S. B., and Nelkin, B. D. (1996) Mol. Cell. Biol. 16, 5335-5345
32. Benz, E. J., Jr., Murnane, M. J., Tonkonow, B. L., Berman, B. W., Mazur, E. M., Cavallesco, C., Jenko, T., Snyder, E. L., Forget, B. G., and Hoffman, R. (1980) Proc. Natl. Acad. Sci. U.S.A. 77, 3509-3513
33. Rutherford, T., Clegg, J. B., Higgs, D. R., Jones, R. W., Thompson, J., and Weatherall, D. J. (1981) Proc. Natl. Acad. Sci. U.S.A. 78, 348-352
34. Brown, B. A., Padgett, R. W., Hardies, S. C., Hutchison, C. A., 3rd, and Edgell, M. H. (1982) Proc. Natl. Acad. Sci. U.S.A. 79, 2753-2757
35. Charnay, P., and Maniatis, T. (1983) Science 220, 1281-1283
36. Fraser, P. J., and Curtis, P. J. (1987) Genes Dev. 1, 855-861
37. Macleod, K., and Plumb, M. (1991) Mol. Cell. Biol. 11, 4324-4332
38. Leder, A., Kuo, A., Shen, M. M., and Leder, P. (1992) Development 116, 1041-1049
39. Palis, J., and Yoder, M. C. (2001) Exp. Hematol. 29, 927-936
40. Kingsley, P. D., Malik, J., Emerson, R. L., Bushnell, T. P., McGrath, K. E., Bloedorn, L. A., Bulger, M., and Palis, J. (2006) Blood 107, 1665-1672
41. Trimborn, T., Gribnau, J., Grosveld, F., and Fraser, P. (1999) Genes Dev. 13, 112-124
42. Zhang, S., Qian, X., Redman, C., Bliskovski, V., Ramsay, E. S., Lowy, D. R., and Mock, B. A. (2003) Oncogene 22, 2285-2295
43. Mukhopadhyay, N. K., Cinar, B., Mukhopadhyay, L., Lutchman, M., Ferdinand, A. S., Kim, J., Chung, L. W., Adam, R. M., Ray, S. K., Leiter, A. B., Richie, J. P., Liu, B. C., and Freeman, M. R. (2007) Mol. Endocrinol. 21, 2056-2070
44. Shi, Y., Sawada, J., Sui, G., Affar el, B., Whetstine, J. R., Lan, F., Ogawa, H., Luke, M. P., Nakatani, Y., and Shi, Y. (2003) Nature 422, 735-738