Antinociceptive activities of the methanol extract of the bulbs of Dioscorea bulbifera L. var sativa in mice is dependent of NO-cGMP-ATP-sensitive-K+ channel activation

Journal of Ethnopharmacology

Volumn 128, Issue 3, 2010, Pages 567-574

  Nguelefack, Télesphore B ^a   Dutra, Rafael C ^b   Paszcuk, Ana F ^b   Andrade, Edinéia L ^b   Tapondjou, Léon A ^a   Calixto, João B ^b  

^a UNIVERSITY OF DSCHANG   (Cameroon)

^b FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

Author keywords

Antinociceptive; Dioscorea bulbifera; Inflammatory pain; Neuropathic pain; NO cGMP K+

Indexed keywords

ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; CAPSAZEPINE; CYCLIC GMP; DIOSCOREA BULBIFERA EXTRACT; DIPYRONE; GABAPENTIN; GLIBENCLAMIDE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIOSCOREA BULBIFERA; DRUG MECHANISM; FEMALE; HYPERALGESIA; MALE; MOUSE; NEUROPATHIC PAIN; NOCICEPTION; NONHUMAN; PLANT BULB; SOLVENT EXTRACTION; YAM;

ANIMALS; CYCLIC GMP; FEMALE; FREUND'S ADJUVANT; GLYBURIDE; HYPERALGESIA; INFLAMMATION; KATP CHANNELS; MALE; METHANOL; MICE; NEURALGIA; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; PAIN; PHYTOTHERAPY; PLANT EXTRACTS; PLANT ROOTS;

DIOSCOREA BULBIFERA; MUS;

EID: 77951204545     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2010.01.061     Document Type: Article

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