Antinociceptive properties of the hydroalcoholic extract and preliminary study of a xanthone isolated from Polygala cyparissias (Polygalaceae)

Life Sciences

Volumn 61, Issue 16, 1997, Pages 1619-1630

  De Campos, Rafael O P ^a   Santos, Adair R S ^a   Vaz, Zulma R ^a   Pinheiro, Tania R ^a   Pizzolatti, Moacir G ^a   Filho, Valdir Cechinel ^c   Monache, Franco Delle ^b   Yunes, Rosendo A ^a   Calixto, João B ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^b CATHOLIC UNIVERSITY   (Italy)

^c NONE

Author keywords

1,7 dihydroxy 2,3 dimethoxy xanthone; Antinociception; Bradykinin; Capsaicin; Formalin; Hyperalgesia; Mice; Polygala cyparissias; Substance P

Indexed keywords

ACETYLSALICYLIC ACID; MORPHINE; NALOXONE; PLANT EXTRACT; XANTHONE DERIVATIVE;

ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG ISOLATION; EDEMA; INTRAPERITONEAL DRUG ADMINISTRATION; LICKING; MALE; MOTOR COORDINATION; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; TRADITIONAL MEDICINE; ULTRAVIOLET SPECTROPHOTOMETRY; VEGETATION; WRITHING TEST;

ABDOMINAL PAIN; ACETIC ACID; ANALGESIA; ANALGESICS; ANIMALS; ASPIRIN; BRADYKININ; CAPSAICIN; ETHANOL; HEAT; MALE; PAIN; PAIN MEASUREMENT; PLANT EXTRACTS; PLANTS, MEDICINAL; RATS; RATS, WISTAR; SUBSTANCE P; WATER; XANTHENES; XANTHONES;

ANIMALIA; POLYGALA; POLYGALA CYPARISSIAS; POLYGALACEAE;

EID: 0030772643     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(97)00741-8     Document Type: Article

References (37)

1. R. WASICKY. Anais da Faculdade de Farmácia de Odontologia da Universidade de São Paula. 4 189-217, Universidade de São Paulo, São Paulo (1945).
2. Y. ZHANG, K. TAKASHINA, H. SAITO, N. NISHIYAMA, Biol. Pharm. Bull. 17 866-868 (1994).
3. J.J. HOFFMANN, R.M. WIEDHOPF, J.R.COLE, J. Pharm. Sci. 66 586-587 (1977).
4. R. STEVENSON, J. V. WEBER, J. Nat. Prod. 54 310-314.
5. D. ZHANG, T. MIYASE, M. KUROYANAGI, K. UMEHARA, A UENO, Chem Pharm Bull 43 115-120(1995).
6. M. YOSHIKAWA, T. MURAKAMI, T. UENO, M. KADOYA, H. MATSUDA, J YAMAHARA, N. MURAKAMI, Chem. Pharm. Bull 43 350-352 (1995).
7. T. MIYASE, H. SAITOH, K. SHIOKAWA, A. UENO, Chem. Pharm. Bull 43 466-472 (1995)
8. D. ZHANG, T. MIYASE, M. KUROYANAGI, K. UMEHARA, A. UENO, Chem. Pharm. Bull 43 966-970 (1995).
9. H. SAITOH, T. MIYASE, A. UENO, K. ATARASHI, Y. SAIKI, Chem. Pharm. Bull 42 641-645 (1994).
10. C.H. ANDRADE, R.B. FO, O.R. GOTTLIEB, E.R. SILVEIRA, Lloydia 40 344-346 (1977).
11. Y. IKEDA, K. SUGAMA, M. MARUNO, Chem. Pharm. Bull 42 2305-2308 (1994).
12. S. GHOSAL, S. BANERJEE, R.B. CHAUHAN, R.S. SRIVASTAVA, J. Chem. Soc. 7 740-743 (1977).
13. XORGE A. DOMINGUEZ S., M. GLADY SOSA U., CLAUDIO ORTIZ, J. JAKUPOVIC, Planta Med. 56 126-127 (1990).
14. D.L. DREYER, J.H. BOURELL, Phytochemistry 20 493-495 (1981).
15. M. ZIMMERMANN, Pain 16 109-110 (1983).
16. A.R.S. SANTOS, V. CECHINEL FILHO, R. NIERO, A.M. VIANA, F.N. MORENO, M.M. CAMPOS, R.A. YUNES, J.B. CALIXTO, J. Pharm. Pharmacol. 46 755-759 (1994).
17. C.R. CORRÊA, J.B. CALIXTO, Br. J. Pharmacol. 110 193-198 (1993).
18. C.R. CORRÊA, D.J. KYLE, S. CHAKRAVARTY, J.B. CALIXTO, Br. J. Pharmacol. 117 552-558 (1996).
19. S. HUNSKAAR, O. FARMER, K. HOLE, J. Neurosci. Meth. 14 69-76 (1985).
20. T. SAKURADA, K. KATSUMATA, K. TAN-NO, S. SAKURADA, K. KISARA, Neuropharmacology 31 1279-1285 (1992).
21. Z.R. VAZ, V. CECHINEL FILHO, R.A. YUNES, J.B. CALIXTO, J. Pharmacol. Exp. Ther. 278 304-312 (1996).
22. N.B. EDDY, D. LEIMBACK, J. Pharmacol. Exp. Ther. 107 385-393 (1953).
23. N.W. DUHAM, T.S. MIYA, J. Am. Pharm. Assoc. 46 208-209 (1957).
24. R.O.P. DE CAMPOS, R.V. ALVES, D.J. KYLE, S. CHAKRAVARTY, B.J. MAVUNKEL, J.B. CALIXTO, Eur. J. Pharmacol. 316 277-286 (1996).
25. L.O. RANDALL, J.J. SELLITO, Arch. Int. Pharmacodyn. Ther. 111 409-419 (1957).
26. AB. MALMBERG, T.L. YAKSH, J. Pharmacol. Exp. Ther. 263 136-146 (1992).
27. L. SEGUIN, S. LE MAROUILLE-GIRARDON, M.J. MILLAN, Pain 61 325-343 (1995).
28. M. SHIBATA, T. OHKUBO, H. TAKAHASHI, R. INOKI, Pain 38 347-352 (1989).
29. A.R. SANTOS, J.B. CALIXTO, Tachykinins' 95 (From Basic Science to Clinical Applications) p. 163 (1995).
30. A.B. MALMBERG, T.L. YAKSH, J. Neurosci. 15 2768-2776 (1995).
31. F. GORSKI, C.R. CORRÊA, V.CECHINEL FILHO, R.A. YUNES, J.B. CALIXTO, J. Pharm. Pharmacol. 45 1046-1049 (1993).
32. K.S.TRATSK, M.M. CAMPOS, A.R.S. SANTOS, T.R. PINHEIRO, M.G. PIZZOLATTI, R.A. YUNES, V. CECHINEL FILHO, J.B. CALIXTO, XIV Simpósio de Plantas Medicinais do Brasil. p. 102 (1996).
33. A.H. COSTELLO, K.M. HARGREAVES, Eur. J. Pharmacol. 171 259-263 (1989).
34. A.J. DAVIS, M.N. PERKINS, Br. J. Pharmacol. 113 63-68 (1994).
35. A.J. DAVIS, M.N. PERKINS, Br. J. Pharmacol. 118 2206-2212 (1996).
36. C.A. MAGGI, Gen. Pharmacol. 26 911-944 (1995).
37. D. REGOLI, A. BOUDON, J.L. FAUCHERE, Pharmacol. Rev. 46 551-599 (1994).