Single-cell enzyme concentrations, kinetics, and inhibition analysis using high-density hydrodynamic cell isolation arrays

Analytical Chemistry

Volumn 78, Issue 14, 2006, Pages 4925-4930

  Di Carlo, Dino ^a   Aghdam, Nima ^a   Lee, Luke P ^a  

^a University of California at Berkeley   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INCUBATION; INHIBITION ANALYSIS; NORDIHYDROGUAIARETIC ACID (NDGA); ON-CHIP SAMPLE PREPARATION;

CELLS; CENTRIFUGATION; ESTERS; HYDRODYNAMICS; IMAGE PROCESSING; MICROSCOPIC EXAMINATION; PROBLEM SOLVING; ROBUSTNESS (CONTROL SYSTEMS);

ENZYMES;

CARBOXYLASE; CELL ENZYME; DIMETICONE; ENZYME INHIBITOR; FLUORESCENT DYE; NORDIHYDROGUAIARETIC ACID; REAGENT;

ARTICLE; CELL COUNT; CELL FUNCTION; CELL ISOLATION; CELL TYPE; CENTRIFUGATION; CHEMICAL ANALYSIS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EMBRYO; ENZYME ANALYSIS; ENZYME ASSAY; ENZYME KINETICS; FLUOROMETRY; HUMAN; HUMAN CELL; HYDRODYNAMICS; IMAGE PROCESSING; MICROARRAY ANALYSIS; MICROFLUIDIC ANALYSIS; MICROSCOPY; PROCESS DESIGN; QUANTITATIVE ANALYSIS; RESPONSE VARIABLE; SYSTEMS BIOLOGY; TECHNIQUE; TIME;

CARBOXYLESTERASE; CELL LINE; CELL SEPARATION; HUMANS; KINETICS; MICROARRAY ANALYSIS; MOLECULAR STRUCTURE; NORDIHYDROGUAIARETIC ACID;

EID: 33746263955     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac060541s     Document Type: Article

References (35)

1. Rao, C. V.; Wolf, D. M.; Arkin, A. P. Nature 2002, 420, 231-237.
2. Kuang, Y.; Biran, I.; Walt, D. R. Anal. Chem. 2004, 76, 6282-6286.
3. Lidstrom, M. E.; Meldrum, D. R. Nat. Rev. Microbiol. 2003, 1, 158-164.
4. Martin, J. C.; Swartzendruber, D. E. Science 1980, 207, 199-201.
5. Nolan, J. P.; Sklar, L. A. Nat. Biotechnol. 1998, 16, 633-638.
6. Griffin, S.; Taggart, C. C.; Greene, C. M.; O'Neill, S.; McElvaney, N. G. FEBS Lett. 2003, 546, 233-236.
7. Perlman, Z. E.; Slack, M. D.; Feng, Y.; Mitchison, T. J.; Wu, L. F.; Altschuler, S. J. Science 2004, 306, 1194-1198.
8. Wheeler, A. R.; Throndset, W. R.; Whelan, R. J.; Leach, A. M.; Zare, R. N.; Liao, Y. H.; Farrell, K.; Manger, I. D.; Daridon, A. Anal. Chem. 2003, 75, 3581-3586.
9. Yang, M. S.; Li, C. W.; Yang, J. Anal. Chem. 2002, 74, 3991-4001.
10. Voldman, J.; Gray, M. L.; Toner, M.; Schmidt, M. A. Anal. Chem. 2002, 74, 3984-3990.
11. Peng, X. Y.; Li, P. C. H. Anal. Chem. 2004, 76, 5273-5281.
12. Seger, U.; Gawad, S.; Johann, R.; Bertsch, A.; Renaud, P. Lab Chip 2004, 4, 148-151.
13. Wu, H. K.; Wheeler, A.; Zare, R. N. Proc. Natl. Acad. Sci. U.S.A. 2004, 101, 12809-12813.
14. Li, P. C. H.; de Camprieu, L.; Cai, J.; Sangar, M. Lab Chip 2004, 4, 174-180.
15. Li, X. J.; Li, P. C. H. Anal. Chem. 2005, 77, 4315-4322.
16. Tanase, M.; Felton, E. J.; Gray, D. S.; Hultgren, A.; Chen, C. S.; Reich, D. H. Lab Chip 2005, 5, 598-605.
17. Rettig, J. R.; Folch, A. Anal. Chem. 2005, 77, 5628-5634.
18. Chin, V. I.; Taupin, P.; Sanga, S.; Scheel, J.; Gage, F. H.; Bhatia, S. N. Biotechnol. Bioeng. 2004, 88, 399-415.
19. Revzin, A.; Sekine, K.; Sin, A.; Tompkins, R. G.; Toner, M. Lab Chip 2005, 5, 30-37.
20. Taff, B. M.; Voldman, J. Anal. Chem. 2005, 77, 7976-7983.
21. Neuman, K. C.; Chadd, E. H.; Liou, G. F.; Bergman, K.; Block, S. M. Biophys. J. 1999, 77, 2856-2863.
22. Satoh, T.; Hosokawa, M. Annu. Rev. Pharmacol. Toxicol. 1998, 38, 257-288.
23. Schegg, K. M.; Welch, W. Biochim. Biophys. Acta 1984, 788, 167-180.
24. Soriano, A. F.; Helfrich, B.; Chan, D. C.; Heasley, L. E.; Bunn, P. A.; Chou, T. C. Cancer Res. 1999, 59, 6178-6184.
25. Gnabre, J. N.; Brady, J. N.; Clanton, D. J.; Ito, Y.; Dittmer, J.; Bates, R. B.; Huang, R. C. C. Proc. Natl. Acad. Sci. U.S.A. 1995, 92, 11239-11243.
26. van Puijenbroek, A. A. F. L.; Wissink, S.; van der Saag, P. T.; Peppelenbosch, M. P. Cytokine 1999, 11, 104-110.
27. Hofmann, J.; Sernetz, M. Anal. Biochem. 1983, 22, 180-186.
28. Breeuwer, P.; Drocourt, J. L.; Bunschoten, N.; Zwietering, M. H.; Rombouts, F. M.; Abee, T. Appl. Environ.l Microbiol. 1995, 61, 1614-1619.
29. Naoum, H.; Van Nes, J. J.; Kappert, H. J.; Beynen, A. C. J. Anim. Physiol. Anim. Nutr. 2002, 86, 105-110.
30. Scheppach, W.; Pomare, E. W.; Elia, M.; Cummings, J. H. Clin. Sci. 1991, 80, 177-182.
31. Wolfe, A. J. Microbiol. Mol. Biol. Rev. 2005, 69, 12.
32. Fiedler, F.; Hinz, H. Eur. J. Biochem. 1994, 33, 75-81.
33. Boonacker, E.; Van Noorden, C. J. F. J. Histochem. Cytochem. 2001, 49, 1473-1486.
34. Urano, Y.; Kamiya, M.; Kanda, K.; Ueno, T.; Hirose, K.; Nagano, T. J. Am. Chem. Soc. 2005, 127, 4888-4894.
35. Bencharit, S.; Morton, C. L.; Howard-Williams, E. L.; Danks, M. K.; Potter, P. M.; Redinbo, M. R. Nat. Struct. Biol. 2002, 9, 337-342.