Virtual screening for the identification of novel nonsteroidal glucocorticoid modulators

Journal of Medicinal Chemistry

Volumn 53, Issue 8, 2010, Pages 3065-3074

  Onnis, Valeria ^a   Kinsella, Gemma K ^a   Carta, Giorgio ^a   Jagoe, William N ^a   Price, Trevor ^a   Williams, D Clive ^a   Fayne, Darren ^a   Lloyd, David G ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; GLUCOCORTICOID RECEPTOR; INTERLEUKIN 1; INTERLEUKIN 6; LIGAND; MDG 169; UNCLASSIFIED DRUG;

ARTICLE; BINDING COMPETITION; CYTOKINE PRODUCTION; DRUG DESIGN; FLUORESCENCE POLARIZATION IMMUNOASSAY; HUMAN; HUMAN CELL; MATHEMATICAL MODEL; PHARMACOPHORE;

BINDING SITES; BINDING, COMPETITIVE; CELL LINE; COMPUTER SIMULATION; DATABASES, FACTUAL; DEXAMETHASONE; DIBENZAZEPINES; DRUG DESIGN; DRUG SYNERGISM; FLUORESCENCE POLARIZATION; HETEROCYCLIC COMPOUNDS, 3-RING; HUMANS; INTERLEUKIN-1; INTERLEUKIN-6; LIGANDS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RECEPTORS, GLUCOCORTICOID;

EID: 77951141381     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm901452y     Document Type: Article

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