Inhibitory effect of resveratrol derivative BTM-0512 on high glucose-induced cell senescence involves dimethylaminohydrolase/asymmetric dimethylarginine pathway

Clinical and Experimental Pharmacology and Physiology

Volumn 37, Issue 5-6, 2010, Pages 630-635

  Yuan, Qiong ^a   Peng, Jun ^a   Liu, Si Yu ^a   Wang, Chen Jing ^a   Xiang, Da Xiong ^a   Xiong, Xiao Ming ^a   Hu, Chang Ping ^a   Li, Yuan Jian ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

BTM 0512; Dimethylarginine dimethylaminohydrolase; Hyperglycaemia; Senescence; Sirtuin 1

Indexed keywords

3,5,4' TRIMETHOXYSTILBENE; BETA GALACTOSIDASE; DIMETHYLARGININASE; DIMETHYLARGININE DIMETHYLAMINOHYDROLASE 2; ENZYME INHIBITOR; GLUCOSE; HYDROLASE; MESSENGER RNA; N(G),N(G) DIMETHYLARGININE; NITRIC OXIDE SYNTHASE; RESVERATROL; SIRTUIN 1; SPLIMTOMICIN; STILBENE DERIVATIVE; UNCLASSIFIED DRUG; 3,4',5-TRIMETHOXYSTILBENE; AMIDASE; ANTIOXIDANT; ARGININE; DIMETHYLARGININE; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; SIRT1 PROTEIN, HUMAN;

ARTICLE; CELL AGING; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME REGULATION; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; SENESCENCE; ANALOGS AND DERIVATIVES; BIOSYNTHESIS; CELL LINE; CULTURE TECHNIQUE; DOSE RESPONSE; DRUG EFFECTS; ENZYMOLOGY; GENETICS; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VASCULAR ENDOTHELIUM;

AMIDOHYDROLASES; ANTIOXIDANTS; ARGININE; CELL AGING; CELL CULTURE TECHNIQUES; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; GENE EXPRESSION; GLUCOSE; HUMANS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIRTUIN 1; STILBENES;

EID: 77951127089     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2010.05368.x     Document Type: Article

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