메뉴 건너뛰기




Volumn 382, Issue 1, 2010, Pages 1-31

A rat brain atlas of urotensin-II receptor expression and a review of central urotensin-II effects

Author keywords

Behavioral control; Cardiovascular control; Central nervous system; Urotensin II; UT receptor

Indexed keywords

GSK 248451; LIGAND; PALOSURAN; UFP 803; UNCLASSIFIED DRUG; URANTIDE; UROTENSIN II; G PROTEIN COUPLED RECEPTOR; UROTENSIN; UTS2R PROTEIN, RAT;

EID: 77951100875     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-010-0503-z     Document Type: Review
Times cited : (12)

References (42)
  • 2
    • 33747051728 scopus 로고    scopus 로고
    • Renal and vascular actions of urotensin II
    • DOI 10.1038/sj.ki.5001621, PII 5001621
    • N Ashton 2006 Renal and vascular actions of urotensin II Kidney Int 70 4 624 629 5001621 [pii] 10.1038/sj.ki.5001621 10.1038/sj.ki.5001621 1:CAS:528:DC%2BD28XnvVyltL0%3D 16807543 (Pubitemid 44215334)
    • (2006) Kidney International , vol.70 , Issue.4 , pp. 624-629
    • Ashton, N.1
  • 3
    • 33745024110 scopus 로고    scopus 로고
    • The peptidic urotensin-II receptor ligand GSK248451 possesses less intrinsic activity than the low-efficacy partial agonists SB-710411 and urantide in native mammalian tissues and recombinant cell systems
    • 0706716 [pii] 10.1038/sj.bjp. 0706716 10.1038/sj.bjp.0706716 1:CAS:528:DC%2BD28XksFSgurk%3D 16547525
    • DJ Behm G Stankus, et al. 2006 The peptidic urotensin-II receptor ligand GSK248451 possesses less intrinsic activity than the low-efficacy partial agonists SB-710411 and urantide in native mammalian tissues and recombinant cell systems Br J Pharmacol 148 2 173 190 0706716 [pii] 10.1038/sj.bjp. 0706716 10.1038/sj.bjp.0706716 1:CAS:528:DC%2BD28XksFSgurk%3D 16547525
    • (2006) Br J Pharmacol , vol.148 , Issue.2 , pp. 173-190
    • Behm, D.J.1    Stankus, G.2
  • 4
    • 33751582536 scopus 로고    scopus 로고
    • Urotensin-II and cardiovascular diseases
    • DOI 10.1007/s11906-006-0026-7
    • N Bousette A Giaid 2006 Urotensin-II and cardiovascular diseases Curr Hypertens Rep 8 6 479 483 10.1007/s11906-006-0026-7 1:CAS:528:DC%2BD28XhtlansrvE 17139807 (Pubitemid 44842774)
    • (2006) Current Hypertension Reports , vol.8 , Issue.6 , pp. 479-483
    • Bousette, N.1    Giaid, A.2
  • 5
    • 0041430625 scopus 로고    scopus 로고
    • Functional and binding characterizations of urotensin II-related peptides in human and rat urotensin II-receptor assay
    • 10.1124/jpet.103.052415. jpet.103.052415 [pii] 10.1124/jpet.103.052415 1:CAS:528:DC%2BD3sXmvVehtbk%3D 12807997
    • A Brkovic A Hattenberger, et al. 2003 Functional and binding characterizations of urotensin II-related peptides in human and rat urotensin II-receptor assay J Pharmacol Exp Ther 306 3 1200 1209 10.1124/jpet.103.052415. jpet.103.052415 [pii] 10.1124/jpet.103.052415 1:CAS:528:DC%2BD3sXmvVehtbk%3D 12807997
    • (2003) J Pharmacol Exp Ther , vol.306 , Issue.3 , pp. 1200-1209
    • Brkovic, A.1    Hattenberger, A.2
  • 6
    • 0036791620 scopus 로고    scopus 로고
    • A new ligand for the urotensin II receptor
    • 10.1038/sj.bjp. 0704895 10.1038/sj.bjp.0704895 1:CAS:528: DC%2BD38Xns1Ciuro%3D 12237249
    • V Camarda R Guerrini, et al. 2002 A new ligand for the urotensin II receptor Br J Pharmacol 137 3 311 314 10.1038/sj.bjp. 0704895 10.1038/sj.bjp.0704895 1:CAS:528:DC%2BD38Xns1Ciuro%3D 12237249
    • (2002) Br J Pharmacol , vol.137 , Issue.3 , pp. 311-314
    • Camarda, V.1    Guerrini, R.2
  • 7
    • 30344465324 scopus 로고    scopus 로고
    • In vitro and in vivo pharmacological characterization of the novel UT receptor ligand [Pen5, DTrp7, Dab8]urotensin II(4-11) (UFP-803)
    • 0706438 [pii]. 10.1038/sj.bjp. 0706438 10.1038/sj.bjp.0706438 1:CAS:528:DC%2BD28XitVSltA%3D%3D 16273120
    • V Camarda M Spagnol, et al. 2006 In vitro and in vivo pharmacological characterization of the novel UT receptor ligand [Pen5, DTrp7, Dab8]urotensin II(4-11) (UFP-803) Br J Pharmacol 147 1 92 100 0706438 [pii]. 10.1038/sj.bjp. 0706438 10.1038/sj.bjp.0706438 1:CAS:528:DC%2BD28XitVSltA%3D%3D 16273120
    • (2006) Br J Pharmacol , vol.147 , Issue.1 , pp. 92-100
    • Camarda, V.1    Spagnol, M.2
  • 8
    • 3843128483 scopus 로고    scopus 로고
    • Urotensin-II receptor peptide agonists
    • DOI 10.1002/med.20001
    • A Carotenuto P Grieco, et al. 2004 Urotensin-II receptor peptide agonists Med Res Rev 24 5 577 588 10.1002/med.20001 10.1002/med.20001 1:CAS:528:DC%2BD2MXht1WitLbK 15224381 (Pubitemid 39038229)
    • (2004) Medicinal Research Reviews , vol.24 , Issue.5 , pp. 577-588
    • Carotenuto, A.1    Grieco, P.2    Novellino, E.3    Rovero, P.4
  • 10
    • 0035960874 scopus 로고    scopus 로고
    • The urotensin II receptor is expressed in the cholinergic mesopontine tegmentum of the rat
    • DOI 10.1016/S0006-8993(01)03208-5, PII S0006899301032085
    • SD Clark HP Nothacker, et al. 2001 The urotensin II receptor is expressed in the cholinergic mesopontine tegmentum of the rat Brain Res 923 1-2 120 127 S0006-8993(01)03208-5 [pii] 10.1016/S0006-8993(01)03208-5 1:CAS:528: DC%2BD3MXovF2jsLY%3D 11743979 (Pubitemid 34024943)
    • (2001) Brain Research , vol.923 , Issue.1-2 , pp. 120-127
    • Clark, S.D.1    Nothacker, H.-P.2    Wang, Z.3    Saito, Y.4    Leslie, F.M.5    Civelli, O.6
  • 11
    • 4644332005 scopus 로고    scopus 로고
    • Pharmacology of the urotensin-II receptor antagonist palosuran (ACT-058362; 1-[2-(4-benzyl-4-hydroxy-piperidin-1-yl)-ethyl]-3-(2-methyl- quinolin-4-yl)-urea sulfate salt): First demonstration of a pathophysiological role of the urotensin system
    • 10.1124/jpet.104.068320. jpet.104.068320 [pii] 10.1124/jpet.104.068320 1:CAS:528:DC%2BD2cXosVKrt70%3D 15146030
    • M Clozel C Binkert, et al. 2004 Pharmacology of the urotensin-II receptor antagonist palosuran (ACT-058362; 1-[2-(4-benzyl-4-hydroxy-piperidin-1-yl)- ethyl]-3-(2-methyl-quinolin-4-yl)-urea sulfate salt): first demonstration of a pathophysiological role of the urotensin system J Pharmacol Exp Ther 311 1 204 212 10.1124/jpet.104.068320. jpet.104.068320 [pii] 10.1124/jpet.104.068320 1:CAS:528:DC%2BD2cXosVKrt70%3D 15146030
    • (2004) J Pharmacol Exp Ther , vol.311 , Issue.1 , pp. 204-212
    • Clozel, M.1    Binkert, C.2
  • 14
    • 42049112557 scopus 로고    scopus 로고
    • Behavioral actions of urotensin-II
    • S0196-9781(08)00005-3 [pii] 10.1016/j.peptides.2007.12.016 10.1016/j.peptides.2007.12.016 1:CAS:528:DC%2BD1cXkvVOltbo%3D 18294732
    • JC Do Rego J Leprince, et al. 2008 Behavioral actions of urotensin-II Peptides 29 5 838 844 S0196-9781(08)00005-3 [pii] 10.1016/j.peptides.2007.12.016 10.1016/j.peptides.2007.12.016 1:CAS:528:DC%2BD1cXkvVOltbo%3D 18294732
    • (2008) Peptides , vol.29 , Issue.5 , pp. 838-844
    • Do Rego, J.C.1    Leprince, J.2
  • 15
    • 53149138960 scopus 로고    scopus 로고
    • Characterization of urotensin II, distribution of urotensin II, urotensin II-related peptide and UT receptor mRNAs in mouse: Evidence of urotensin II at the neuromuscular junction
    • JNC5624 [pii] 10.1111/j.1471-4159.2008.05624.x 10.1111/j.1471-4159.2008. 05624.x 1:CAS:528:DC%2BD1cXhtlajtb3F 18710417
    • C Dubessy D Cartier, et al. 2008 Characterization of urotensin II, distribution of urotensin II, urotensin II-related peptide and UT receptor mRNAs in mouse: evidence of urotensin II at the neuromuscular junction J Neurochem 107 2 361 374 JNC5624 [pii] 10.1111/j.1471-4159.2008.05624.x 10.1111/j.1471-4159.2008.05624.x 1:CAS:528:DC%2BD1cXhtlajtb3F 18710417
    • (2008) J Neurochem , vol.107 , Issue.2 , pp. 361-374
    • Dubessy, C.1    Cartier, D.2
  • 16
    • 0037171726 scopus 로고    scopus 로고
    • Identification of nonpeptidic urotensin II receptor antagonists by virtual screening based on a pharmacophore model derived from structure-activity relationships and nuclear magnetic resonance studies on urotensin II
    • DOI 10.1021/jm0111043
    • S Flohr M Kurz, et al. 2002 Identification of nonpeptidic urotensin II receptor antagonists by virtual screening based on a pharmacophore model derived from structure-activity relationships and nuclear magnetic resonance studies on urotensin II J Med Chem 45 9 1799 1805 jm0111043 [pii] 10.1021/jm0111043 1:CAS:528:DC%2BD38XitVOjurs%3D 11960491 (Pubitemid 34415375)
    • (2002) Journal of Medicinal Chemistry , vol.45 , Issue.9 , pp. 1799-1805
    • Flohr, S.1    Kurz, M.2    Kostenis, E.3    Brkovich, A.4    Fournier, A.5    Klabunde, T.6
  • 18
    • 0037179641 scopus 로고    scopus 로고
    • A new, potent urotensin II receptor peptide agonist containing a Pen residue at the disulfide bridge
    • jm025549i [pii] 10.1021/jm025549i 1:CAS:528:DC%2BD38Xms1CksbY%3D 12238917
    • P Grieco A Carotenuto, et al. 2002 A new, potent urotensin II receptor peptide agonist containing a Pen residue at the disulfide bridge J Med Chem 45 20 4391 4394 jm025549i [pii] 10.1021/jm025549i 1:CAS:528:DC%2BD38Xms1CksbY%3D 12238917
    • (2002) J Med Chem , vol.45 , Issue.20 , pp. 4391-4394
    • Grieco, P.1    Carotenuto, A.2
  • 22
    • 63849273731 scopus 로고    scopus 로고
    • The effects of benzodiazepines on urotensin II-stimulated norepinephrine release from rat cerebrocortical slices
    • 108/4/1177 [pii] 10.1213/ane.0b013e3181981faa 10.1213/ane. 0b013e3181981faa 1:CAS:528:DC%2BD1MXjtlOqtrk%3D 19299782
    • Y Kawaguchi T Ono, et al. 2009 The effects of benzodiazepines on urotensin II-stimulated norepinephrine release from rat cerebrocortical slices Anesth Analg 108 4 1177 1181 108/4/1177 [pii] 10.1213/ane.0b013e3181981faa 10.1213/ane.0b013e3181981faa 1:CAS:528:DC%2BD1MXjtlOqtrk%3D 19299782
    • (2009) Anesth Analg , vol.108 , Issue.4 , pp. 1177-1181
    • Kawaguchi, Y.1    Ono, T.2
  • 23
    • 42149083241 scopus 로고    scopus 로고
    • Central and peripheral cardiovascular, ventilatory, and motor effects of trout urotensin-II in the trout
    • DOI 10.1016/j.peptides.2007.06.020, PII S0196978107002197
    • JC Le Mevel F Lancien, et al. 2008 Central and peripheral cardiovascular, ventilatory, and motor effects of trout urotensin-II in the trout Peptides 29 5 830 837 S0196-9781(07)00219-7 [pii] 10.1016/j.peptides.2007.06.020 10.1016/j.peptides.2007.06.020 17681644 (Pubitemid 351540832)
    • (2008) Peptides , vol.29 , Issue.5 , pp. 830-837
    • Le Mevel, J.-C.1    Lancien, F.2    Mimassi, N.3    Leprince, J.4    Conlon, J.M.5    Vaudry, H.6
  • 25
    • 0037251222 scopus 로고    scopus 로고
    • Central cardiovascular action of urotensin II in conscious rats
    • 10.1097/01.hjh.0000045518.21915.ec 10.1097/00004872-200301000-00026 1:CAS:528:DC%2BD3sXlsV2iuw%3D%3D 12544448
    • Y Lin T Tsuchihashi, et al. 2003 Central cardiovascular action of urotensin II in conscious rats J Hypertens 21 1 159 165 10.1097/01.hjh. 0000045518.21915.ec 10.1097/00004872-200301000-00026 1:CAS:528: DC%2BD3sXlsV2iuw%3D%3D 12544448
    • (2003) J Hypertens , vol.21 , Issue.1 , pp. 159-165
    • Lin, Y.1    Tsuchihashi, T.2
  • 26
    • 0242441544 scopus 로고    scopus 로고
    • Central cardiovascular action of urotensin II in spontaneously hypertensive rats
    • DOI 10.1291/hypres.26.839
    • Y Lin T Tsuchihashi, et al. 2003 Central cardiovascular action of urotensin II in spontaneously hypertensive rats Hypertens Res 26 10 839 845 10.1291/hypres.26.839 1:CAS:528:DC%2BD2cXis1KhtA%3D%3D 14621188 (Pubitemid 37406953)
    • (2003) Hypertension Research , vol.26 , Issue.10 , pp. 839-845
    • Lin, Y.1    Tsuchihashi, T.2    Matsumura, K.3    Fukuhara, M.4    Ohya, Y.5    Fujii, K.6    Iida, M.7
  • 27
    • 0036710537 scopus 로고    scopus 로고
    • Cardiovascular effects of urotensin II in different brain areas
    • DOI 10.1016/S0196-9781(02)00104-3, PII S0196978102001043
    • Y Lu CJ Zou, et al. 2002 Cardiovascular effects of urotensin II in different brain areas Peptides 23 9 1631 1635 S0196978102001043 [pii] 10.1016/S0196-9781(02)00104-3 1:CAS:528:DC%2BD38Xms12gsbY%3D 12217424 (Pubitemid 35246283)
    • (2002) Peptides , vol.23 , Issue.9 , pp. 1631-1635
    • Lu, Y.1    Zou, C.-J.2    Huang, D.-W.3    Tang, C.-S.4
  • 28
    • 0033776533 scopus 로고    scopus 로고
    • Orphan-receptor ligand human urotensin II: Receptor localization in human tissues and comparison of vasoconstrictor responses with endothelin-1
    • 10.1038/sj.bjp. 0703601 10.1038/sj.bjp.0703601 1:CAS:528: DC%2BD3cXnsVygt7g%3D 11015293
    • JJ Maguire RE Kuc, et al. 2000 Orphan-receptor ligand human urotensin II: receptor localization in human tissues and comparison of vasoconstrictor responses with endothelin-1 Br J Pharmacol 131 3 441 446 10.1038/sj.bjp. 0703601 10.1038/sj.bjp.0703601 1:CAS:528:DC%2BD3cXnsVygt7g%3D 11015293
    • (2000) Br J Pharmacol , vol.131 , Issue.3 , pp. 441-446
    • Maguire, J.J.1    Kuc, R.E.2
  • 30
    • 34547870172 scopus 로고    scopus 로고
    • Role of urotensin II and its receptor in health and disease
    • DOI 10.1007/s00540-007-0524-z
    • J McDonald M Batuwangala, et al. 2007 Role of urotensin II and its receptor in health and disease J Anesth 21 3 378 389 10.1007/s00540-007-0524-z 10.1007/s00540-007-0524-z 17680191 (Pubitemid 47261270)
    • (2007) Journal of Anesthesia , vol.21 , Issue.3 , pp. 378-389
    • McDonald, J.1    Batuwangala, M.2    Lambert, D.G.3
  • 31
    • 45849086109 scopus 로고    scopus 로고
    • Urotensin II evokes neurotransmitter release from rat cerebrocortical slices
    • S0304-3940(08)00771-4 [pii] 10.1016/j.neulet.2008.05.096 10.1016/j.neulet.2008.05.096 1:CAS:528:DC%2BD1cXnvVOgsbY%3D 18572318
    • T Ono Y Kawaguchi, et al. 2008 Urotensin II evokes neurotransmitter release from rat cerebrocortical slices Neurosci Lett 440 3 275 279 S0304-3940(08)00771-4 [pii] 10.1016/j.neulet.2008.05.096 10.1016/j.neulet.2008. 05.096 1:CAS:528:DC%2BD1cXnvVOgsbY%3D 18572318
    • (2008) Neurosci Lett , vol.440 , Issue.3 , pp. 275-279
    • Ono, T.1    Kawaguchi, Y.2
  • 32
    • 42049112735 scopus 로고    scopus 로고
    • Urotensin-II and cardiovascular remodeling
    • DOI 10.1016/j.peptides.2007.09.012, PII S0196978107003919
    • P Papadopoulos N Bousette, et al. 2008 Urotensin-II and cardiovascular remodeling Peptides 29 5 764 769 S0196-9781(07)00391-9 [pii] 10.1016/j.peptides.2007.09.012 10.1016/j.peptides.2007.09.012 1:CAS:528:DC%2BD1cXkvVOltLo%3D 17988761 (Pubitemid 351522368)
    • (2008) Peptides , vol.29 , Issue.5 , pp. 764-769
    • Papadopoulos, P.1    Bousette, N.2    Giaid, A.3
  • 33
    • 1642368204 scopus 로고    scopus 로고
    • Urantide: An ultrapotent urotensin II antagonist peptide in the rat aorta
    • 10.1038/sj.bjp. 0705555 140/7/1155 [pii] 10.1038/sj.bjp.0705555 1:CAS:528:DC%2BD2cXpvV2ntQ%3D%3D 14645137
    • R Patacchini P Santicioli, et al. 2003 Urantide: an ultrapotent urotensin II antagonist peptide in the rat aorta Br J Pharmacol 140 7 1155 1158 10.1038/sj.bjp. 0705555 140/7/1155 [pii] 10.1038/sj.bjp.0705555 1:CAS:528:DC%2BD2cXpvV2ntQ%3D%3D 14645137
    • (2003) Br J Pharmacol , vol.140 , Issue.7 , pp. 1155-1158
    • Patacchini, R.1    Santicioli, P.2
  • 35
    • 5144234214 scopus 로고    scopus 로고
    • Urotensin II in the cardiovascular system
    • DOI 10.1016/j.peptides.2004.04.017, PII S0196978104003341
    • AM Richards C Charles 2004 Urotensin II in the cardiovascular system Peptides 25 10 1795 1802 S0196-9781(04)00334-1 [pii] 10.1016/j.peptides.2004.04. 017 10.1016/j.peptides.2004.04.017 1:CAS:528:DC%2BD2cXotlWgtLg%3D 15476948 (Pubitemid 39346223)
    • (2004) Peptides , vol.25 , Issue.10 SPEC. ISS. , pp. 1795-1802
    • Richards, A.M.1    Charles, C.2
  • 36
    • 4644306988 scopus 로고    scopus 로고
    • Emerging roles of urotensin-II in cardiovascular disease
    • DOI 10.1016/j.pharmthera.2004.07.004, PII S0163725804001019
    • FD Russell 2004 Emerging roles of urotensin-II in cardiovascular disease Pharmacol Ther 103 3 223 243 S0163-7258(04)00101-9 [pii] 10.1016/j.pharmthera. 2004.07.004 10.1016/j.pharmthera.2004.07.004 1:CAS:528:DC%2BD2cXotFCls7s%3D 15464591 (Pubitemid 39298465)
    • (2004) Pharmacology and Therapeutics , vol.103 , Issue.3 , pp. 223-243
    • Russell, F.D.1
  • 38
    • 0028943373 scopus 로고
    • A novel putative neuropeptide receptor expressed in neural tissue, including sensory epithelia
    • S0006-291X(85)71563-X [pii] 10.1006/bbrc.1995.1563 10.1006/bbrc.1995.1563 1:CAS:528:DyaK2MXltVGktL8%3D 7733947
    • M Tal DA Ammar, et al. 1995 A novel putative neuropeptide receptor expressed in neural tissue, including sensory epithelia Biochem Biophys Res Commun 209 2 752 759 S0006-291X(85)71563-X [pii] 10.1006/bbrc.1995.1563 10.1006/bbrc.1995.1563 1:CAS:528:DyaK2MXltVGktL8%3D 7733947
    • (1995) Biochem Biophys Res Commun , vol.209 , Issue.2 , pp. 752-759
    • Tal, M.1    Ammar, D.A.2
  • 39
    • 0035828410 scopus 로고    scopus 로고
    • Role of urotensin II in patients on dialysis
    • DOI 10.1016/S0140-6736(01)06002-0
    • K Totsune K Takahashi, et al. 2001 Role of urotensin II in patients on dialysis Lancet 358 9284 810 811 S0140-6736(01)06002-0 [pii] 10.1016/S0140-6736(01)06002-0 10.1016/S0140-6736(01)06002-0 1:CAS:528: DC%2BD3MXmvVKmsbg%3D 11564491 (Pubitemid 32868735)
    • (2001) Lancet , vol.358 , Issue.9284 , pp. 810-811
    • Totsune, K.1    Takahashi, K.2    Arihara, Z.3    Sone, M.4    Satoh, F.5    Ito, S.6    Kimura, Y.7    Sasano, H.8    Murakami, O.9
  • 41
    • 0041331762 scopus 로고    scopus 로고
    • Urotensin II acts centrally to increase epinephrine and ACTH release and cause potent inotropic and chronotropic actions
    • DOI 10.1161/01.HYP.0000084633.85427.E6
    • AM Watson GW Lambert, et al. 2003 Urotensin II acts centrally to increase epinephrine and ACTH release and cause potent inotropic and chronotropic actions Hypertension 42 3 373 379 10.1161/01.HYP.0000084633.85427.E6 01.HYP.0000084633.85427.E6 [pii] 10.1161/01.HYP.0000084633.85427.E6 1:CAS:528:DC%2BD3sXmslSjurk%3D 12885791 (Pubitemid 37093488)
    • (2003) Hypertension , vol.42 , Issue.3 , pp. 373-379
    • Watson, A.M.D.1    Lambert, G.W.2    Smith, K.J.3    May, C.N.4
  • 42
    • 5144220950 scopus 로고    scopus 로고
    • Urotensin II, a novel peptide in central and peripheral cardiovascular control
    • DOI 10.1016/j.peptides.2004.04.016, PII S0196978104003298
    • AM Watson CN May 2004 Urotensin II, a novel peptide in central and peripheral cardiovascular control Peptides 25 10 1759 1766 S0196-9781(04)00329-8 [pii] 10.1016/j.peptides.2004.04.016 10.1016/j.peptides.2004.04.016 1:CAS:528:DC%2BD2cXotlWgtL8%3D 15476943 (Pubitemid 39346218)
    • (2004) Peptides , vol.25 , Issue.10 SPEC. ISS. , pp. 1759-1766
    • Watson, A.M.D.1    May, C.N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.