Urotensin-II receptor ligands. From agonist to antagonist activity

Journal of Medicinal Chemistry

Volumn 48, Issue 23, 2005, Pages 7290-7297

  Grieco, Paolo ^a   Carotenuto, Alfonso ^a   Campiglia, Pietro ^a   Marinelli, Luciana ^a   Lama, Teresa ^a   Patacchini, Riccardo ^c   Santicioli, Paolo ^d   Maggi, Carlo A ^d   Rovero, Paolo ^b   Novellino, Ettore ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

^c CHIESI FARMACEUTICI S P A   (Italy)

^d Via Rismondo 12/A ^*  (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DODECYL SULFATE SODIUM; G PROTEIN COUPLED RECEPTOR; LIGAND; LYSINE; P5U; TRYPTOPHAN; TYROSINE; UNCLASSIFIED DRUG; URANTIDE; UROTENSIN 2 RECEPTOR AGONIST; UROTENSIN 2 RECEPTOR ANTAGONIST; UROTENSIN II RECEPTOR; VASOCONSTRICTOR AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANISOTROPY; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DISULFIDE BOND; DRUG POTENCY; DRUG STRUCTURE; LIGAND BINDING; MALE; MATHEMATICAL COMPUTING; NONHUMAN; RAT; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; VASOCONSTRICTION;

ANIMALS; AORTA, THORACIC; CHO CELLS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRICETINAE; CRICETULUS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MICELLES; MODELS, MOLECULAR; MUSCLE RELAXATION; MUSCLE, SMOOTH, VASCULAR; PEPTIDES, CYCLIC; PROTEIN STRUCTURE, SECONDARY; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; RECEPTORS, G-PROTEIN-COUPLED; SODIUM DODECYL SULFATE; STRUCTURE-ACTIVITY RELATIONSHIP; UROTENSINS;

EID: 28544431577     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm058043j     Document Type: Article

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