Skin microvascular reactivity in trained adolescents

European Journal of Applied Physiology

Volumn 108, Issue 6, 2010, Pages 1201-1208

  Roche, Denise M ^a   Rowland, T W ^b   Garrard, M ^a   Marwood, S ^a   Unnithan, V B ^a  

^a LIVERPOOL HOPE UNIVERSITY   (United Kingdom)

^b BAYSTATE MEDICAL CENTER   (United States)

Author keywords

Adolescents; Cutaneous vascular conductance; Endothelium; Exercise training; Post occlusive reactive hyperaemia; Skin blood flow

Indexed keywords

ADOLESCENT; ARTICLE; EXERCISE; FITNESS; FUNCTIONS OF THE SKIN AND ITS APPENDAGES; HUMAN; MALE; MICROCIRCULATION; PHYSIOLOGY; SKIN; VASCULARIZATION; VASODILATATION;

ADOLESCENT; EXERCISE; HUMANS; MALE; MICROCIRCULATION; PHYSICAL EXERTION; PHYSICAL FITNESS; SKIN; SKIN PHYSIOLOGICAL PHENOMENA; VASODILATION;

EID: 77951093044     PISSN: 14396319     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00421-009-1328-7     Document Type: Article

References (45)

1. RA Abbott MA Harkness PS Davies 2002 Correlation of habitual physical activity levels with flow-mediated dilation of the brachial artery in 5-10 year old children Atherosclerosis 160 233 239 10.1016/S0021-9150(01)00566-4 1:CAS:528:DC%2BD38Xit1al 11755942 (Pubitemid 34076659)
2. MA Black DJ Green NT Cable 2008 Exercise prevents age-related decline in nitric-oxide-mediated vasodilator function in cutaneous microvessels J Physiol 586 3511 3524 10.1113/jphysiol.2008.153742 1:CAS:528:DC%2BD1cXptlanur8%3D 18483071 (Pubitemid 352003880)
3. Y Boegli G Gremion S Golay S Kubli L Liaudet PF Leyvraz B Waeber F Feihl 2003 Endurance training enhances vasodilation induced by nitric oxide in human skin J Invest Dermatol 121 1197 1204 10.1046/j.1523-1747.2003.12518.x 1:CAS:528:DC%2BD3sXpsVChsro%3D 14708626 (Pubitemid 37430993)
4. L Bungum K Kvernebo P ∅ian JM Maltau 1996 Laser doppler-recorded reactive hyperaemia in the forearm skin during the menstrual cycle Br J Obstet Gynaecol 103 70 75 1:STN:280:DyaK287ptl2msA%3D%3D 8608101
5. DS Celermajer KE Sorensen C Bull J Robinson JE Deanfield 1994 Endothelium-dependent dilation in the systemic arteries of asymptomatic subjects relates to coronary risk factors and their interaction J Am Coll Cardiol 24 1468 1474 1:STN:280:DyaK2M%2FhsFGjsg%3D%3D 7930277
6. N Charkoudian 2003 Skin blood flow in adult human thermoregulation: how it works, when it does not, and why Mayo Clin Proc 78 603 612 10.4065/78.5.603 12744548
7. P Clarkson HE Montgomery MJ Mullen AE Donald AJ Powe T Bull M Jubb M World JE Deanfield 1999 Exercise training enhances endothelial function in young men J Am Coll Cardiol 33 1379 1385 10.1016/S0735-1097(99)00036-4 1:STN:280:DyaK1M3gvVSrtw%3D%3D 10193742
8. JL Cracowski CT Minson M Salvat-Melis JR Halliwill 2006 Methodological issues in the assessment of skin microvascular endothelial function in humans Trends Pharmacol Sci 27 503 508 10.1016/j.tips.2006.07.008 1:CAS:528: DC%2BD28XotlGktrs%3D 16876881 (Pubitemid 44233694)
9. CA DeSouza LF Shapiro CM Clevenger FA Dinenno KD Monahan H Tanaka DR Seals 2000 Regular aerobic exercise prevents and restores age-related declines in endothelium-dependent vasodilation in healthy men Circulation 102 1351 1357 1:STN:280:DC%2BD3cvks1WgtQ%3D%3D 10993851
10. Esper RJ, Nordaby RA, Vilariño JO, Paragano A, Cacharrón JL, Muchado RA (2006) Endothelial dysfunction: a comprehensive appraisal. Cardiovasc Diabetol 5:4. Available via http://www.cardiab.com/content/5/1/4. doi: 10.1186/1475-2840-5-4. Accessed January 14 2009
11. F Franzoni F Galetta C Morizzo V Lubrano C Palombo G Santoro E Ferrannini A Quiñones-Galvan 2004 Effects of age and physical fitness on microcirculatory function Clin Sci 106 329 335 10.1042/CS20030229 14588072 (Pubitemid 38365841)
12. C Goto Y Higashi M Kimura K Noma K Hara K Nakagawa M Kawamura K Chayama M Yoshizumi I Nara 2003 Effect of different intensities of exercise on endothelium-dependent vasodilation in humans. Role of endothelium-dependent nitric oxide and oxidative stress Circulation 108 530 535 10.1161/01.CIR. 0000080893.55729.28 12874192 (Pubitemid 36961165)
13. DJ Green DT Fowler JG O'Driscoll BA Blanksby RR Taylor 1996 Endothelium-derived nitric oxide activity in forearm vessels of tennis players J Appl Physiol 81 943 948 1:CAS:528:DyaK28XlvVGqtLo%3D 8872666
14. DJ Green A Maiorana G O'Driscoll R Taylor 2004 Effect of exercise training on endothelium-derived nitric oxide function in humans J Physiol 561 1 25 10.1113/jphysiol.2004.068197 1:CAS:528:DC%2BD2cXhtVehurbL 15375191 (Pubitemid 39549463)
15. R Hambrecht E Fiehn C Weigl S Gielen C Hamann R Kaiser J Yu V Adams J Niebauer G Schuler 1998 Regular physical exercise corrects endothelial dysfunction and improves exercise capacity in patients with chronic heart failure Circulation 98 2709 2715 1:CAS:528:DyaK1MXitFaqtw%3D%3D 9851957
16. R Hambrecht V Adams S Erbs, et al. 2003 Regular physical activity improves endothelial function in patients with coronary artery disease by increasing phosphorylation of endothelial nitric oxide synthase Circulation 107 3152 3158 10.1161/01.CIR.0000074229.93804.5C 1:CAS:528:DC%2BD3sXkslKgtrk%3D 12810615 (Pubitemid 36793084)
17. O Hamdy S Ledbury C Mullooly C Jarema S Porter K Ovalle A Moussa A Caselli AE Caballero PA Economides A Veves ES Horton 2003 Lifestyle modification improves endothelial function in obese subjects with the insulin resistance syndrome Diabetes Care 26 2119 2125 10.2337/diacare.26.7.2119 12832323 (Pubitemid 41184262)
18. E Heylen B Simon F Guerrero JP Elkaïm B Saïag J Mansourati 2005 Reactive hyperaemia in the forearm skin of highly trained windsurfers Int J Sports Med 26 822 826 10.1055/s-2005-837452 1:STN:280:DC%2BD2MnjvVaqtA%3D%3D 16320164 (Pubitemid 41807739)
19. LA Holowatz CS Thompson CT Minson WL Kenney 2005 Mechanisms of acetylcholine-mediated vasodilation in young and aged human skin J Physiol 563 965 973 10.1113/jphysiol.2004.080952 1:CAS:528:DC%2BD2MXivVGhtbc%3D 15661816 (Pubitemid 40425609)
20. LL Ji 2008 Modulation of skeletal muscle antioxidant defense by exercise: role of redox signaling Free Radic Biol Med 44 142 152 10.1016/j.freeradbiomed. 2007.02.031 1:CAS:528:DC%2BD1cXlvVygtg%3D%3D 18191750
21. DL Kellogg Jr Y Liu IF Kosiba D O'Donnell 1999 Role of nitric oxide in the vascular effects of local warming of the skin in humans J Appl Physiol 86 1185 1190 1:CAS:528:DyaK1MXivVGlsbw%3D 10194201
22. DL Kellogg Jr JL Zhao U Coey JV Green 2005 Acetylcholine-induced vasodilation is mediated by nitric oxide and prostaglandins in human skin J Appl Physiol 98 629 632 10.1152/japplphysiol.00728.2004 1:CAS:528: DC%2BD2MXhsVKmtb4%3D 15649880 (Pubitemid 40129975)
23. AS Kelly RJ Wetzsteon DR Kaiser J Steinberger AJ Bank DR Dengel 2004 Inflammation, insulin, and endothelial function in overweight children and adolescents: the role of exercise J Pediatr 145 731 736 10.1016/j.jpeds.2004.08. 004 1:CAS:528:DC%2BD2cXhtVCls7zL 15580192 (Pubitemid 39586608)
24. F Khan FC Green JS Forsyth SA Greene AD Morris JJ Belch 2003 Impaired microvascular function in normal children: effects of adiposity and poor glucose handling J Physiol 551 705 711 10.1113/jphysiol.2003.045351 1:CAS:528:DC%2BD3sXosFCrt7k%3D 12824443 (Pubitemid 37121725)
25. BA Kingwell B Sherrard GL Jennings AM Dart 1997 Four weeks of cycle training increases basal production of nitric oxide from the forearm Am J Physiol 272 H1070 H1077 1:CAS:528:DyaK2sXit1Srs74%3D 9087577 (Pubitemid 27146723)
26. HD Kvernmo A Stefanovska KA Kirkebøen B ∅sterud K Kvernebo 1998 Enhanced endothelium-dependent vasodilation in human skin vasculature induced by physical conditioning E J Appl Physiol Occup Physiol 79 30 36 10.1007/s004210050469 1:CAS:528:DyaK1cXntlygtbs%3D (Pubitemid 29041369)
27. H Lenasi M Strucl 2004 Effect of regular physical training on cutaneous microvascular reactivity Med Sci Sports Exerc 36 606 612 10.1249/01.MSS. 0000121948.86377.51 15064588 (Pubitemid 38452033)
28. A Maiorana G O'Driscoll C Cheetham L Dembo K Stanton C Goodman R Taylor D Green 2001 The effect of combined aerobic and resistance exercise training on vascular function in type 2 diabetes J Am Coll Cardiol 38 860 866 10.1016/S0735-1097(01)01439-5 1:STN:280:DC%2BD3MvosFymug%3D%3D 11527646 (Pubitemid 32835765)
29. T Mano T Masuyama K Yamamoto, et al. 1996 Endothelial dysfunction in the early stage of atherosclerosis precedes appearance of intimal lesions assessable with intravascular ultrasound Am Heart J 131 231 238 10.1016/S0002-8703(96) 90346-4 1:STN:280:DyaK287msFWmtw%3D%3D 8579013 (Pubitemid 26043378)
30. MF Meyer D Lieps H Schatz M Pfohl 2008 Impaired flow-mediated vasodilation in type 2 diabetes: lack of relation to microvascular dysfunction Microvasc Res 76 61 65 10.1016/j.mvr.2008.03.001 1:CAS:528:DC%2BD1cXns1agsLc%3D 18448131
31. F Morales R Graff AJ Smit S Bertuglia AL Petoukhova W Steenbergen P Leger G Rakhorst 2005 How to assess post-occlusive reactive hyperaemia by means of laser Doppler perfusion monitoring: application of a standardised protocol to patients with peripheral arterial obstructive disease Microvasc Res 69 17 23 10.1016/j.mvr.2005.01.006 15797256 (Pubitemid 40410464)
32. GE Nilsson T Tenland PA Orberg 1980 Evaluation of a laser Doppler flowmeter for measurement of tissue blood flow IEEE Trans Biomed Eng 27 597 604 10.1109/TBME.1980.326582 1:STN:280:DyaL3M%2FmvVersQ%3D%3D 6449469 (Pubitemid 11442084)
33. K Pahkala OJ Heinonen H Lagström P Hakala O Simell JS Viikari T Rönnemaa M Hernelahti L Sillanmäki OT Raitakari 2008 Vascular endothelial function and leisure-time physical activity in adolescents Circulation 118 2353 2359 10.1161/CIRCULATIONAHA.108.791988 1:CAS:528: DC%2BD1cXhsVaisb%2FP 19015403
34. DM Roche S Edmunds T Cable M Didi G Stratton 2008 Skin microvascular reactivity in children and adolescents with type 1 diabetes in relation to levels of physical activity and aerobic fitness Pediatr Exerc Sci 20 426 438 19168919
35. R Ross 1993 The pathogenesis of atherosclerosis: a perspective for the 1990s Nature 362 801 809 10.1038/362801a0 1:CAS:528:DyaK3sXktVGqu7c%3D 8479518 (Pubitemid 23132154)
36. M Roustit GH Simmons JP Baguet P Carpentier JL Cracowski 2008 Discrepancy between simultaneous digital skin microvascular and brachial artery macrovascular post-occlusive hyperemia in systemic sclerosis J Rheumatol 35 1576 1583 18597404
37. WC Sessa K Pritchard N Seyedi J Wang TH Hintze 1994 Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression Circ Res 74 349 353 1:CAS:528: DyaK2cXhvVyjurw%3D 7507417 (Pubitemid 24029168)
38. HC Stary 1989 Evolution and progression of atherosclerotic lesions in coronary arteries of children and young adults Arteriosclerosis 9 Suppl 1 I19 I32 1:STN:280:DyaL1M7gsVyhsQ%3D%3D 2912430
39. S Taddei F Galetta A Virdis L Ghiadoni G Salvetti F Franzoni C Giusti A Salvetti 2000 Physical activity prevents age-related impairment in nitric oxide availability in elderly athletes Circulation 101 2896 2901 1:CAS:528: DC%2BD3cXkvFWlsbw%3D 10869260 (Pubitemid 30415878)
40. A Veves R Saouaf VM Donaghue CA Mullooly JA Kistler JM Giurini ES Horton RA Fielding 1997 Aerobic exercise capacity remains normal despite impaired endothelial function in the micro- and macrocirculation of physically active IDDM patients Diabetes 46 1846 1852 10.2337/diabetes.46.11.1846 1:CAS:528:DyaK2sXntVKitL8%3D 9356035 (Pubitemid 27456420)
41. JS Wang C Lan SY Chen MK Wong 2002 Tai Chi Chuan training is associated with enhanced endothelium-dependent dilation in skin vasculature of healthy older men J Am Geriatr Soc 50 1024 1030 10.1046/j.1532-5415.2002.50256.x 12110061 (Pubitemid 34666307)
42. K Watts P Beye A Siafarikas EA Davis TW Jones G O'Driscoll DJ Green 2004 Exercise training normalizes vascular dysfunction and improves central adiposity in obese adolescents J Am Coll Cardiol 43 1823 1827 10.1016/j.jacc.2004.01.032 15145107 (Pubitemid 38622522)
43. BJ Wong BW Wilkins LA Holowatz CT Minson 2003 Nitric oxide synthase inhibition does not alter the reactive hyperemic response in the cutaneous circulation J Appl Physiol 95 504 510 1:CAS:528:DC%2BD3sXmsF2hurk%3D 12692141
44. X Zhang SP Zhao XP Li M Gao QC Zhou 2000 Endothelium-dependent and -independent functions are impaired in patients with coronary heart disease Atherosclerosis 149 19 24 10.1016/S0021-9150(99)00288-9 1:CAS:528: DC%2BD3cXhsVagur8%3D 10704610 (Pubitemid 30125967)
45. JL Zhao PE Pergola LJ Roman DL Kellogg Jr 2004 Bioactive nitric oxide concentration does not increase during reactive hyperemia in human skin J Appl Physiol 96 628 632 10.1152/japplphysiol.00639.2003 1:CAS:528: DC%2BD2cXhsVyjsL0%3D 14715681 (Pubitemid 38140165)