-
1
-
-
0032544087
-
Flavonoids: A class of modulators with bifunctional interactions at vicinal ATP- And steroid-binding sites on mouse P-glycoprotein
-
DOI 10.1073/pnas.95.17.9831
-
Conseil G, Baubichon-Cortary H, Dayan G, Jault JM, Barron D, Pietro A. Flavonoids: a class of modulators with bifunctional interactions at vicinal ATP-and steroid binding sites on mouse P-glycoprotein. Proc Natl Acad Sci USA 1998; 95: 9831-9836. (Pubitemid 28415255)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.17
, pp. 9831-9836
-
-
Conseil, G.1
Baubichon-Cortay, H.2
Dayan, G.3
Jault, J.-M.4
Barron, D.5
Di Pietro, A.6
-
2
-
-
33749444911
-
The potential of flavonoids to influence drug metabolism and pharmacokinetics by local gastrointestinal mechanisms
-
DOI 10.2174/138920006778520570
-
Cermak R, Wolffram S. The potential of flavonoids to influence drug metabolism and pharmacokinetics by local gastrointestinal mechanisms. Curr Drug Metab 2006; 7: 729-744. (Pubitemid 44509679)
-
(2006)
Current Drug Metabolism
, vol.7
, Issue.7
, pp. 729-744
-
-
Cermak, R.1
Wolffram, S.2
-
3
-
-
0024366081
-
Modulating effect of plant flavonoids on the mutagenicity of N-methyl-N'-nitro-N-nitrosoguanidine
-
Francis AR, Shetty TK, Bhattacharya RK. Modulating effect of plant flavonoids on the mutagenicity of N-methyl-N-nitro-N-nitrosoguanidine. Carcinogenesis 1989; 10: 1953-1955. (Pubitemid 19244876)
-
(1989)
Carcinogenesis
, vol.10
, Issue.10
, pp. 1953-1955
-
-
Francis, A.R.1
Shetty, T.K.2
Bhattacharya, R.K.3
-
4
-
-
0028318752
-
The correlation between active oxygens scavenging and antioxidative effects of flavonoids
-
DOI 10.1016/0891-5849(94)90202-X
-
Hanasaki Y, Ogawa S, Fukui S. The correlation between active oxygens scavenging and antioxidative effects of flavonoids. Free Radic Biol Med 1994; 16: 845-850. (Pubitemid 24193534)
-
(1994)
Free Radical Biology and Medicine
, vol.16
, Issue.6
, pp. 845-850
-
-
Hanasaki, Y.1
Ogawa, S.2
Fukui, S.3
-
5
-
-
0344255791
-
Morin sulfates/glucuronides exert anti-inflammatory activity on activated macrophages and decreased the incidence of septic shock
-
Fang SH, Hou YC, Chang WC, Hsiu SL, Chao PD, Chiang BL. Morin sulfates/glucuronides exert anti-inflammatory activity on activated macrophages and decreased the incidence of septic shock. Life Sci 2003; 74: 743-756.
-
(2003)
Life Sci
, vol.74
, pp. 743-756
-
-
Fang, S.H.1
Hou, Y.C.2
Chang, W.C.3
Hsiu, S.L.4
Chao, P.D.5
Chiang, B.L.6
-
6
-
-
30644465031
-
Effects of morin pretreatment on the pharmacokinetics of diltiazem and its major metabolite, desacetyldiltiazem in rats
-
Choi JS, Han HK. Effects of morin pretreatment on the pharmacokinetics of diltiazem and its major metabolite, desacetyldiltiazem in rats. Arch Pharm Res 2005; 28: 970-976.
-
(2005)
Arch Pharm Res
, vol.28
, pp. 970-976
-
-
Choi, J.S.1
Han, H.K.2
-
7
-
-
85088190889
-
Altered pharmacokinetics of paclitaxel by the concomitant use of morin in rats
-
Choi HJ, Choi JS, Han HK. Altered pharmacokinetics of paclitaxel by the concomitant use of morin in rats. Arch Pharm Res 2005; 28: 970-976.
-
(2005)
Arch Pharm Res
, vol.28
, pp. 970-976
-
-
Choi, H.J.1
Choi, J.S.2
Han, H.K.3
-
8
-
-
34248327577
-
Effects of morin on the pharmacokinetics of etoposide in rats
-
DOI 10.1002/bdd.539
-
Li X, Yun JK, Choi JS. Effects of morin on the pharmacokinetics of etoposide in rats. Biopharm Drug Dispos 2007; 28: 151-156. (Pubitemid 46730923)
-
(2007)
Biopharmaceutics and Drug Disposition
, vol.28
, Issue.3
, pp. 151-156
-
-
Li, X.1
Yun, J.-K.2
Choi, J.-S.3
-
9
-
-
42549117615
-
Effects of morin on the pharmacokinetics of nicardipine after oral and intravenous administration of nicardipine in rats
-
DOI 10.1211/jpp.60.5.0008
-
Piao YJ, Choi JS. Effects of morin on the pharmacokinetics of nicardipine after oral and intravenous administration of nicardipine in rats. J Pharm Pharmacol 2008; 60: 625-629. (Pubitemid 351589050)
-
(2008)
Journal of Pharmacy and Pharmacology
, vol.60
, Issue.5
, pp. 625-629
-
-
Piao, Y.-J.1
Choi, J.-S.2
-
10
-
-
0029028792
-
Overlapping substrate specificities and tissue distribution of cytochrome P450, 3A and P-glycoprotein: Implications for drug delivery in cancer chemotherapy
-
Wacher VJ, Wu CY, Benet LZ. Overlapping substrate specificities and tissue distribution of cytochrome P450, 3A and P-glycoprotein: implications for drug delivery in cancer chemotherapy. Mol Carcinogen 1995; 13: 129-134.
-
(1995)
Mol Carcinogen
, vol.13
, pp. 129-134
-
-
Wacher, V.J.1
Wu, C.Y.2
Benet, L.Z.3
-
11
-
-
0031962002
-
P-glycoprotein transporters and the gastrointestinal tract: Evaluation of the potential in vivo relevance of in vitro data employing talinolol as model compound
-
Spahn-Langguth H, Baktir G, Radschuweit A et al. P-Glycoprotein transporters and the gastrointestinal tract: evaluation of the potential in vivo relevance of in vitro data employing talinolol as model compound. Int J Clin Pharmacol Ther 1998; 36: 16-24. (Pubitemid 28031804)
-
(1998)
International Journal of Clinical Pharmacology and Therapeutics
, vol.36
, Issue.1
, pp. 16-24
-
-
Spahn-Langguth, H.1
Baktir, G.2
Radschuweit, A.3
Okyar, A.4
Terhaag, B.5
Ader, P.6
Hanafy, A.7
Langguth, P.8
-
12
-
-
77951090065
-
Intestinal secretion of talinolol: Competitive and P-gp-antibody-induced inhibition of transport in studies with Caco-2 cells
-
Hilgendorf C, Spahn-Langguth H, Langguth P. Intestinal secretion of talinolol: competitive and P-gp-antibody-induced inhibition of transport in studies with Caco-2 cells. Naunyn Schmiedebergs Arch Pharmacol 1997; 355: R-453.
-
(1997)
Naunyn Schmiedebergs Arch Pharmacol
, vol.355
-
-
Hilgendorf, C.1
Spahn-Langguth, H.2
Langguth, P.3
-
13
-
-
21444438059
-
Regional difference in P-glycoprotein function in rat intestine
-
Iida A, Tomita M, Hayashi M. Regional difference in P-glycoprotein function in rat intestine. Drug Metab Pharmacokinet 2005; 20: 100-106.
-
(2005)
Drug Metab Pharmacokinet
, vol.20
, pp. 100-106
-
-
Iida, A.1
Tomita, M.2
Hayashi, M.3
-
14
-
-
33748931006
-
Altered oral bioavailability and pharmacokinetics of P-glycoprotein substrates by coadministration of biochanin a
-
DOI 10.1002/jps.20664
-
Peng SX, Ritchie DM, Cousineau M, Danser E, Dewire R, Floden J. Altered oral bioavailability and pharmacokinetics of P-glycoprotein substrates by coadministration of biochanin A. J Pharm Sci 2006; 95: 1984-1993. (Pubitemid 44433029)
-
(2006)
Journal of Pharmaceutical Sciences
, vol.95
, Issue.9
, pp. 1984-1993
-
-
Peng, S.X.1
Ritchie, D.M.2
Cousineau, M.3
Danser, E.4
Dewire, R.5
Floden, J.6
-
15
-
-
0032589932
-
2 receptor antagonists cimetidine and ranitidine by P-glycoprotein in rat intestine and the human colonic cell line Caco-2
-
2 receptor antagonists cimetidine and ranitidine by P-glycoprotein in rat intestine and the human colonic cell line Caco-2. J Pharmacol Exp Ther 1999; 288: 171-178.
-
(1999)
J Pharmacol Exp Ther
, vol.288
, pp. 171-178
-
-
Collett, A.1
Higgs, N.B.2
Sims, E.3
Rowland, M.4
Warhurst, G.5
-
16
-
-
0036246888
-
Resolution of P-glycoprotein and non-P-glycoprotein effects on drug permeability using intestinal tissues from mdr1a (-/-) mice
-
Stephens RH, O'Neill CA, Bennett J et al. Resolution of P-glycoprotein and non-P-glycoprotein effects on drug permeability using intestinal tissues from mdr1a (-/-) mice. Br J Pharmacol 2002; 135: 2038-2046. (Pubitemid 34478317)
-
(2002)
British Journal of Pharmacology
, vol.135
, Issue.8
, pp. 2038-2046
-
-
Stephens, R.H.1
O'Neill, C.A.2
Bennett, J.3
Humphrey, M.4
Henry, B.5
Rowland, M.6
Warhurst, G.7
-
17
-
-
0042905800
-
Novel experimental parameters to quantify the modulation of absorptive and secretory transport of compounds by P-glycoprotein in cell culture models of intestinal epithelium
-
Troutman MD, Thakker DR. Novel experimental parameters to quantify the modulation of absorptive and secretory transport of compounds by P-glycoprotein in cell culture models of intestinal epithelium. Pharm Res 2003; 20: 1210-1224.
-
(2003)
Pharm Res
, vol.20
, pp. 1210-1224
-
-
Troutman, M.D.1
Thakker, D.R.2
-
18
-
-
20744446221
-
Prediction of in vivo intestinal absorption enhancement on P-glycoprotein inhibition, from rat in situ permeability
-
DOI 10.1002/jps.20309
-
Varma MV, Panchagnula R. Prediction of in vivo intestinal absorption enhancement on P-glycoprotein inhibition, from rat in situ permeability. J Pharm Sci 2005; 94: 1694-1704. (Pubitemid 41360864)
-
(2005)
Journal of Pharmaceutical Sciences
, vol.94
, Issue.8
, pp. 1694-1704
-
-
Varma, M.V.S.1
Panchagnula, R.2
-
19
-
-
0029855969
-
Comparison between permeability coefficients in rat and human jejunum
-
DOI 10.1023/A:1016065715308
-
Fagerholm U, Johansson M, Lennernas H. Comparison between permeability coefficients in rat and human jejunum. Pharm Res 1996; 13: 1336-1342. (Pubitemid 26344978)
-
(1996)
Pharmaceutical Research
, vol.13
, Issue.9
, pp. 1336-1342
-
-
Fagerholm, U.1
Johansson, M.2
Lennernas, H.3
-
20
-
-
0035108342
-
Pretreatment with potent P-glycoprotein ligands may increase intestinal secretion in rats
-
DOI 10.1016/S0928-0987(00)00195-0, PII S0928098700001950
-
Hanafy A, Langguth P, Spahn-Langguth H. Pretreatment with potent P-glycoprotein ligands may increase intestinal secretion in rats. Eur J Pharm Sci 2001; 12: 405-415. (Pubitemid 32166739)
-
(2001)
European Journal of Pharmaceutical Sciences
, vol.12
, Issue.4
, pp. 405-415
-
-
Hanafy, A.1
Langguth, P.2
Spahn-Langguth, H.3
-
21
-
-
0035134037
-
A good practice guide to the administration of substances and removal of blood, including routes and volumes
-
Heinz Diehl K, Hull D, Morton D, et al. A good practice guide to the administration of substances and removal of blood, including routes and volumes. J Appl Toxicol 2001; 21: 15-23.
-
(2001)
J Appl Toxicol
, vol.21
, pp. 15-23
-
-
Heinz Diehl, K.1
Hull, D.2
Morton, D.3
-
22
-
-
0003484310
-
-
Food and Drug Administration (FDA). Department of Health and Human Services: Rockville, MD
-
Food and Drug Administration (FDA). Guidance for Industry Bioanalytical Method Validation. Department of Health and Human Services: Rockville, MD, 2001.
-
(2001)
Guidance for Industry Bioanalytical Method Validation
-
-
-
23
-
-
0142010611
-
P-Glycoprotein Increases from Proximal to Distal Regions of Human Small Intestine
-
DOI 10.1023/A:1026183200740
-
Mouly S, Paine MF. P-glycoprotein increases from proximal to distal regions of human small intestine. Pharm Res 2003; 20: 1595-1599. (Pubitemid 37268274)
-
(2003)
Pharmaceutical Research
, vol.20
, Issue.10
, pp. 1595-1599
-
-
Mouly, S.1
Paine, M.F.2
-
24
-
-
0037373359
-
Variability of intestinal expression of P-glycoprotein in healthy volunteers as described by absorption of talinolol from four bioequivalent tablets
-
DOI 10.1002/jps.10327
-
Siegmund W, Ludwig K, Engel G, et al. Variability of intestinal expression of P-glycoprotein in healthy volunteers as described by absorption of talinolol from four bioequivalent tablets. J Pharm Sci 2003; 92: 604-610. (Pubitemid 36258975)
-
(2003)
Journal of Pharmaceutical Sciences
, vol.92
, Issue.3
, pp. 604-610
-
-
Siegmund, W.1
Ludwig, K.2
Engel, G.3
Zschiesche, M.4
Franke, G.5
Hoffmann, A.6
Terhaag, B.7
Weitschies, W.8
-
25
-
-
0035119989
-
In vitro substrate identification studies for P-glycoprotein-mediated transport: Species difference and predictability of in vivo results
-
Yamazaki M, Neway WE, Ohe T et al. In vitro substrate identification studies for P-glycoprotein-mediated transport: species difference and predictability of in vivo results. J Pharmacol Exp Ther 2001; 296: 723-735.
-
(2001)
J Pharmacol Exp Ther
, vol.296
, pp. 723-735
-
-
Yamazaki, M.1
Neway, W.E.2
Ohe, T.3
-
26
-
-
60049089374
-
Concentration-dependent effect of naringin on intestinal absorption of β1-adrenoceptor antagonist talinolol mediated by P-glycoprotein and organic anion transporting polypeptide (Oatp)
-
Shirasaka Y, Li Y, Shibue Y, et al. Concentration-dependent effect of naringin on intestinal absorption of β1-adrenoceptor antagonist talinolol mediated by P-glycoprotein and organic anion transporting polypeptide (Oatp). Pharm Res 2009; 26: 560-567.
-
(2009)
Pharm Res
, vol.26
, pp. 560-567
-
-
Shirasaka, Y.1
Li, Y.2
Shibue, Y.3
-
27
-
-
0034111043
-
P-glycoprotein inhibitor erythromycin increases oral bioavailability of talinolol in humans
-
Schwarz UI, Gramatte T, Krappweis J, Oertel R, Kirch W. P-glycoprotein inhibitor erythromycin increases oral bioavailability of talinolol in humans. Int J Clin Pharmacol Ther 2000; 38: 161-167. (Pubitemid 30193611)
-
(2000)
International Journal of Clinical Pharmacology and Therapeutics
, vol.38
, Issue.4
, pp. 161-167
-
-
Schwarz, U.I.1
Gramatte, T.2
Krappweis, J.3
Oertel, R.4
Kirch, W.5
-
28
-
-
66649103351
-
Intestinal perfusion with mesenteric blood sampling in wild-type and knockout mice: Evaluation of a novel tool in biopharmaceutical drug profiling
-
Mols R, Brouwers J, Schinkel AH, Annaert P, Augustijns P. Intestinal perfusion with mesenteric blood sampling in wild-type and knockout mice: evaluation of a novel tool in biopharmaceutical drug profiling. Drug Metab Dispos 2009; 37: 1334-1337.
-
(2009)
Drug Metab Dispos
, vol.37
, pp. 1334-1337
-
-
Mols, R.1
Brouwers, J.2
Schinkel, A.H.3
Annaert, P.4
Augustijns, P.5
|