-
1
-
-
59849123764
-
The Plasmodium falciparum-induced anion channel of human erythrocytes is an ATP-release pathway
-
Akkaya C, Shumilina E, Bobballa D, Brand VB, Mahmud H, Lang F, and Huber SM (2009) The Plasmodium falciparum-induced anion channel of human erythrocytes is an ATP-release pathway. Pflugers Arch 457:1035-1047.
-
(2009)
Pflugers Arch
, vol.457
, pp. 1035-1047
-
-
Akkaya, C.1
Shumilina, E.2
Bobballa, D.3
Brand, V.B.4
Mahmud, H.5
Lang, F.6
Huber, S.M.7
-
2
-
-
10244219829
-
Plasmodium falciparum likely encodes the principal anion channel on infected human erythrocytes
-
DOI 10.1182/blood-2004-05-2047
-
Alkhalil A, Cohn JV, Wagner MA, Cabrera JS, Rajapandi T, and Desai SA (2004) Plasmodium falciparum likely encodes the principal anion channel on infected human erythrocytes. Blood 104:4279-4286. (Pubitemid 39620183)
-
(2004)
Blood
, vol.104
, Issue.13
, pp. 4279-4286
-
-
Alkhalil, A.1
Cohn, J.V.2
Wagner, M.A.3
Cabrera, J.S.4
Rajapandi, T.5
Desai, S.A.6
-
3
-
-
66849111134
-
Introduction: Cell-based assays for high-throughput screening
-
An WF and Tolliday NJ (2009) Introduction: cell-based assays for high-throughput screening. Methods Mol Biol 486:1-12.
-
(2009)
Methods Mol Biol
, vol.486
, pp. 1-12
-
-
An, W.F.1
Tolliday, N.J.2
-
4
-
-
20444470318
-
High-throughput screening for potent and selective inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase
-
DOI 10.1074/jbc.M501100200
-
Baldwin J, Michnoff CH, Malmquist NA, White J, Roth MG, Rathod PK, and Phillips MA (2005) High-throughput screening for potent and selective inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase. J Biol Chem 280:21847-21853. (Pubitemid 40827835)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.23
, pp. 21847-21853
-
-
Baldwin, J.1
Michnoff, C.H.2
Malmquist, N.A.3
White, J.4
Roth, M.G.5
Rathod, P.K.6
Phillips, M.A.7
-
5
-
-
57649129179
-
Two distinct mechanisms of transport through the plasmodial surface anion channel
-
Bokhari AA, Solomon T, and Desai SA (2008) Two distinct mechanisms of transport through the plasmodial surface anion channel. J Membr Biol 226:27-34.
-
(2008)
J Membr Biol
, vol.226
, pp. 27-34
-
-
Bokhari, A.A.1
Solomon, T.2
Desai, S.A.3
-
6
-
-
33645283641
-
Three types of spontaneously active anionic channels in malaria-infected human red blood cells
-
Bouyer G, Egée S, and Thomas SL (2006) Three types of spontaneously active anionic channels in malaria-infected human red blood cells. Blood Cells Mol Dis 36:248-254.
-
(2006)
Blood Cells Mol Dis
, vol.36
, pp. 248-254
-
-
Bouyer, G.1
Egée, S.2
Thomas, S.L.3
-
7
-
-
0344826477
-
Dependence of Plasmodium falciparum in vitro growth on the cation permeability of the human host erythrocyte
-
DOI 10.1159/000075122
-
Brand VB, Sandu CD, Duranton C, Tanneur V, Lang KS, Huber SM, and Lang F (2003) Dependence of Plasmodium falciparum in vitro growth on the cation permeability of the human host erythrocyte. Cell Physiol Biochem 13:347-356. (Pubitemid 37465150)
-
(2003)
Cellular Physiology and Biochemistry
, vol.13
, Issue.6
, pp. 347-356
-
-
Brand, V.B.1
Sandu, C.D.2
Duranton, C.3
Tanneur, V.4
Lang, K.S.5
Huber, S.M.6
Lang, F.7
-
9
-
-
29144498242
-
Open and closed states of the plasmodial surface anion channel
-
Desai SA (2005) Open and closed states of the plasmodial surface anion channel. Nanomedicine 1:58-66.
-
(2005)
Nanomedicine
, vol.1
, pp. 58-66
-
-
Desai, S.A.1
-
10
-
-
20444490348
-
Plasmodial surface anion channel-independent phloridzin resistance in Plasmodium falciparum in Plasmodium falciparum
-
Desai SA, Alkhalil A, Kang M, Ashfaq U, and Nguyen ML (2005) Plasmodial surface anion channel-independent phloridzin resistance in Plasmodium falciparum. J Biol Chem 280:16861-16867.
-
(2005)
J Biol Chem
, vol.280
, pp. 16861-16867
-
-
Desai, S.A.1
Alkhalil, A.2
Kang, M.3
Ashfaq, U.4
Nguyen, M.L.5
-
11
-
-
0034739003
-
A voltage-dependent channel involved in nutrient uptake by red blood cells infected with the malaria parasite
-
Desai SA, Bezrukov SM, and Zimmerberg J (2000) A voltage-dependent channel involved in nutrient uptake by red blood cells infected with the malaria parasite. Nature 406:1001-1005.
-
(2000)
Nature
, vol.406
, pp. 1001-1005
-
-
Desai, S.A.1
Bezrukov, S.M.2
Zimmerberg, J.3
-
12
-
-
22544453881
-
The no-observed-adverse-effect-level in drug safety evaluations: Use, issues, and definition(s)
-
Dorato MA and Engelhardt JA (2005) The no-observed-adverse-effect-level in drug safety evaluations: use, issues, and definition(s). Regul Toxicol Pharmacol 42:265-274.
-
(2005)
Regul Toxicol Pharmacol
, vol.42
, pp. 265-274
-
-
Dorato, M.A.1
Engelhardt, J.A.2
-
13
-
-
0033636607
-
Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance
-
Fidock DA, Nomura T, Talley AK, Cooper RA, Dzekunov SM, Ferdig MT, Ursos LM, Sidhu AB, Naudé B, Deitsch KW, et al. (2000) Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance. Mol Cell 6:861-871.
-
(2000)
Mol Cell
, vol.6
, pp. 861-871
-
-
Fidock, D.A.1
Nomura, T.2
Talley, A.K.3
Cooper, R.A.4
Dzekunov, S.M.5
Ferdig, M.T.6
Ursos, L.M.7
Sidhu, A.B.8
Naudé, B.9
Deitsch, K.W.10
-
14
-
-
34548480189
-
X-ray structural analysis of Plasmodium falciparum enoyl acyl carrier protein reductase as a pathway toward the optimization of triclosan antimalarial efficacy
-
DOI 10.1074/jbc.M701813200
-
Freundlich JS, Wang F, Tsai HC, Kuo M, Shieh HM, Anderson JW, Nkrumah LJ, Valderramos JC, Yu M, Kumar TR, Valderramos SG, Jacobs WR, Jr., Schiehser GA, Jacobus DP, Fidock DA, and Sacchettini JC (2007) X-ray structural analysis of Plasmodium falciparum enoyl acyl carrier protein reductase as a pathway toward the optimization of triclosan antimalarial efficacy. J Biol Chem 282:25436-25444. (Pubitemid 47372790)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.35
, pp. 25436-25444
-
-
Freundlich, J.S.1
Wang, F.2
Tsai, H.-C.3
Kuo, M.4
Shieh, H.-M.5
Anderson, J.W.6
Nkrumah, L.J.7
Valderramos, J.-C.8
Yu, M.9
Kumar, T.R.S.10
Valderramos, S.G.11
Jacobs Jr., W.R.12
Schiehser, G.A.13
Jacobus, D.P.14
Fidock, D.A.15
Sacchettini, J.C.16
-
15
-
-
13944258184
-
How many functional transport pathways does Plasmodium falciparum induce in the membrane of its host erythrocyte?
-
Ginsburg H and Stein WD (2005) How many functional transport pathways does Plasmodium falciparum induce in the membrane of its host erythrocyte? Trends Parasitol 21:118-121.
-
(2005)
Trends Parasitol
, vol.21
, pp. 118-121
-
-
Ginsburg, H.1
Stein, W.D.2
-
16
-
-
22344431880
-
Malaria parasites are rapidly killed by dantrolene derivatives specific for the plasmodial surface anion channel
-
DOI 10.1124/mol.104.010553
-
Kang M, Lisk G, Hollingworth S, Baylor SM, and Desai SA (2005) Malaria parasites are rapidly killed by dantrolene derivatives specific for the plasmodial surface anion channel. Mol Pharmacol 68:34-40. (Pubitemid 41002942)
-
(2005)
Molecular Pharmacology
, vol.68
, Issue.1
, pp. 34-40
-
-
Kang, M.1
Lisk, G.2
Hollingworth, S.3
Baylor, S.M.4
Desai, S.A.5
-
17
-
-
33751356224
-
Systems biology, metabolic modelling and metabolomics in drug discovery and development
-
DOI 10.1016/j.drudis.2006.10.004, PII S1359644606004181
-
Kell DB (2006) Systems biology, metabolic modelling and metabolomics in drug discovery and development. Drug Discov Today 11:1085-1092. (Pubitemid 44810914)
-
(2006)
Drug Discovery Today
, vol.11
, Issue.23-24
, pp. 1085-1092
-
-
Kell, D.B.1
-
18
-
-
0023145791
-
On the mode of action of phlorizin as an antimalarial agent in in vitro cultures of Plasmodium falciparum
-
Kutner S, Breuer WV, Ginsburg H, and Cabantchik ZI (1987) On the mode of action of phlorizin as an antimalarial agent in in vitro cultures of Plasmodium falciparum. Biochem Pharmacol 36:123-129.
-
(1987)
Biochem Pharmacol
, vol.36
, pp. 123-129
-
-
Kutner, S.1
Breuer, W.V.2
Ginsburg, H.3
Cabantchik, Z.I.4
-
19
-
-
16544376141
-
Channel-induced apoptosis of infected host cells - The case of malaria
-
DOI 10.1007/s00424-004-1254-9
-
Lang F, Lang PA, Lang KS, Brand V, Tanneur V, Duranton C, Wieder T, and Huber SM (2004) Channel-induced apoptosis of infected host cells-the case of malaria. Pflugers Arch 448:319-324. (Pubitemid 40895601)
-
(2004)
Pflugers Archiv European Journal of Physiology
, vol.448
, Issue.3
, pp. 319-324
-
-
Lang, F.1
Lang, P.A.2
Lang, K.S.3
Brand, V.4
Tanneur, V.5
Duranton, C.6
Wieder, T.7
Huber, S.M.8
-
20
-
-
0035289779
-
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
-
DOI 10.1016/S0169-409X(00)00129-0, PII S0169409X00001290
-
Lipinski CA, Lombardo F, Dominy BW, and Feeney PJ (2001) Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv Drug Deliv Rev 46:3-26. (Pubitemid 33653411)
-
(2000)
Advanced Drug Delivery Reviews
, vol.46
, Issue.1-3
, pp. 3-26
-
-
Lipinski, C.A.1
Lombardo, F.2
Dominy, B.W.3
Feeney, P.J.4
-
21
-
-
29144503753
-
The plasmodial surface anion channel is functionally conserved in divergent malaria parasites
-
DOI 10.1128/EC.4.12.2153-2159.2005
-
Lisk G and Desai SA (2005) The plasmodial surface anion channel is functionally conserved in divergent malaria parasites. Eukaryot Cell 4:2153-2159. (Pubitemid 41798320)
-
(2005)
Eukaryotic Cell
, vol.4
, Issue.12
, pp. 2153-2159
-
-
Lisk, G.1
Desai, S.A.2
-
22
-
-
33751167863
-
Specific inhibition of the plasmodial surface anion channel by dantrolene
-
Lisk G, Kang M, Cohn JV, and Desai SA (2006) Specific inhibition of the plasmodial surface anion channel by dantrolene. Eukaryot Cell 5:1882-1893.
-
(2006)
Eukaryot Cell
, vol.5
, pp. 1882-1893
-
-
Lisk, G.1
Kang, M.2
Cohn, J.V.3
Desai, S.A.4
-
23
-
-
34247503700
-
Solute-inhibitor interactions in the plasmodial surface anion channel reveal complexities in the transport process
-
DOI 10.1124/mol.106.030734
-
Lisk G, Scott S, Solomon T, Pillai AD, and Desai SA (2007) Solute-inhibitor interactions in the plasmodial surface anion channel reveal complexities in the transport process. Mol Pharmacol 71:1241-1250. (Pubitemid 46658677)
-
(2007)
Molecular Pharmacology
, vol.71
, Issue.5
, pp. 1241-1250
-
-
Lisk, G.1
Scott, S.2
Solomon, T.3
Pillai, A.D.4
Desai, S.A.5
-
24
-
-
33745041171
-
Plasmodium falciparum ensures its amino acid supply with multiple acquisition pathways and redundant proteolytic enzyme systems
-
DOI 10.1073/pnas.0601876103
-
Liu J, Istvan ES, Gluzman IY, Gross J, and Goldberg DE (2006) Plasmodium falciparum ensures its amino acid supply with multiple acquisition pathways and redundant proteolytic enzyme systems. Proc Natl Acad Sci U S A 103:8840-8845. (Pubitemid 43878106)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.23
, pp. 8840-8845
-
-
Liu, J.1
Istvan, E.S.2
Gluzman, I.Y.3
Gross, J.4
Goldberg, D.E.5
-
25
-
-
33847413750
-
Transport of the essential nutrient isoleucine in human erythrocytes infected with the malaria parasite Plasmodium falciparum
-
Martin RE and Kirk K (2007) Transport of the essential nutrient isoleucine in human erythrocytes infected with the malaria parasite Plasmodium falciparum. Blood 109:2217-2224.
-
(2007)
Blood
, vol.109
, pp. 2217-2224
-
-
Martin, R.E.1
Kirk, K.2
-
26
-
-
65349150510
-
The homeostasis of Plasmodium falciparum-infected red blood cells
-
Mauritz JM, Esposito A, Ginsburg H, Kaminski CF, Tiffert T, and Lew VL (2009) The homeostasis of Plasmodium falciparum-infected red blood cells. PLoS Comput Biol 5:e1000339.
-
(2009)
PLoS Comput Biol
, vol.5
-
-
Mauritz, J.M.1
Esposito, A.2
Ginsburg, H.3
Kaminski, C.F.4
Tiffert, T.5
Lew, V.L.6
-
27
-
-
0036887187
-
Effect of community-wide use of insecticide-treated nets for 3-4 years on malarial morbidity in Tanzania
-
DOI 10.1046/j.1365-3156.2002.00966.x
-
Maxwell CA, Msuya E, Sudi M, Njunwa KJ, Carneiro IA, and Curtis CF (2002) Effect of community-wide use of insecticide-treated nets for 3-4 years on malarial morbidity in Tanzania. Trop Med Int Health 7:1003-1008. (Pubitemid 36960247)
-
(2002)
Tropical Medicine and International Health
, vol.7
, Issue.12
, pp. 1003-1008
-
-
Maxwell, C.A.1
Msuya, E.2
Sudi, M.3
Njunwa, K.J.4
Carneiro, I.A.5
Curtis, C.F.6
-
29
-
-
0025719869
-
Antimalarial effects of peptide inhibitors of a Plasmodium falciparum cysteine proteinase
-
Rosenthal PJ, Wollish WS, Palmer JT, and Rasnick D (1991) Antimalarial effects of peptide inhibitors of a Plasmodium falciparum cysteine proteinase. J Clin Invest 88:1467-1472.
-
(1991)
J Clin Invest
, vol.88
, pp. 1467-1472
-
-
Rosenthal, P.J.1
Wollish, W.S.2
Palmer, J.T.3
Rasnick, D.4
-
30
-
-
0032562763
-
Transport and metabolism of the essential vitamin pantothenic acid in human erythrocytes infected with the malaria parasite Plasmodium falciparum
-
Saliba KJ, Horner HA, and Kirk K (1998) Transport and metabolism of the essential vitamin pantothenic acid in human erythrocytes infected with the malaria parasite Plasmodium falciparum. J Biol Chem 273:10190-10195.
-
(1998)
J Biol Chem
, vol.273
, pp. 10190-10195
-
-
Saliba, K.J.1
Horner, H.A.2
Kirk, K.3
-
31
-
-
54249123267
-
Polymorphisms within PfMDR1 alter the substrate specificity for anti-malarial drugs in Plasmodium falciparum
-
Sanchez CP, Rotmann A, Stein WD, and Lanzer M (2008) Polymorphisms within PfMDR1 alter the substrate specificity for anti-malarial drugs in Plasmodium falciparum. Mol Microbiol 70:786-798.
-
(2008)
Mol Microbiol
, vol.70
, pp. 786-798
-
-
Sanchez, C.P.1
Rotmann, A.2
Stein, W.D.3
Lanzer, M.4
-
32
-
-
38549121773
-
ChemBank: A small-molecule screening and cheminformatics resource database
-
DOI 10.1093/nar/gkm843
-
Seiler KP, George GA, Happ MP, Bodycombe NE, Carrinski HA, Norton S, Brudz S, Sullivan JP, Muhlich J, Serrano M, et al. (2008) ChemBank: a small-molecule screening and cheminformatics resource database. Nucleic Acids Res 36:D351-D359. (Pubitemid 351149748)
-
(2008)
Nucleic Acids Research
, vol.36
, Issue.SUPPL. 1
-
-
Seiler, K.P.1
George, G.A.2
Happ, M.P.3
Bodycombe, N.E.4
Carrinski, H.A.5
Norton, S.6
Brudz, S.7
Sullivan, J.P.8
Muhlich, J.9
Serrano, M.10
Ferraiolo, P.11
Tolliday, N.J.12
Schreiber, S.L.13
Clemons, P.A.14
-
33
-
-
0023478292
-
Data transformations for improved display and fitting of single-channel dwell time histograms
-
Sigworth FJ and Sine SM (1987) Data transformations for improved display and fitting of single-channel dwell time histograms. Biophys J 52:1047-1054.
-
(1987)
Biophys J
, vol.52
, pp. 1047-1054
-
-
Sigworth, F.J.1
Sine, S.M.2
-
34
-
-
33947158084
-
Electrophysiological studies of malaria parasite-infected erythrocytes: Current status
-
DOI 10.1016/j.ijpara.2006.12.013, PII S0020751907000021
-
Staines HM, Alkhalil A, Allen RJ, De Jonge HR, Derbyshire E, Egée S, Ginsburg H, Hill DA, Huber SM, Kirk K, et al. (2007) Electrophysiological studies of malaria parasite-infected erythrocytes: current status. Int J Parasitol 37:475-482. (Pubitemid 46399711)
-
(2007)
International Journal for Parasitology
, vol.37
, Issue.5
, pp. 475-482
-
-
Staines, H.M.1
Alkhalil, A.2
Allen, R.J.3
De Jonge, H.R.4
Derbyshire, E.5
Egee, S.6
Ginsburg, H.7
Hill, D.A.8
Huber, S.M.9
Kirk, K.10
Lang, F.11
Lisk, G.12
Oteng, E.13
Pillai, A.D.14
Rayavara, K.15
Rouhani, S.16
Saliba, K.J.17
Shen, C.18
Solomon, T.19
Thomas, S.L.Y.20
Verloo, P.21
Desai, S.A.22
more..
-
35
-
-
0347418183
-
Furosemide analogues as potent inhibitors of the new permeability pathways of Plasmodium falciparum-infected human erythrocytes
-
DOI 10.1016/j.molbiopara.2003.10.009
-
Staines HM, Dee BC, O'Brien M, Lang HJ, Englert H, Horner HA, Ellory JC, and Kirk K (2004) Furosemide analogues as potent inhibitors of the new permeability pathways of Plasmodium falciparum-infected human erythrocytes. Mol Biochem Parasitol 133:315-318. (Pubitemid 38032879)
-
(2004)
Molecular and Biochemical Parasitology
, vol.133
, Issue.2
, pp. 315-318
-
-
Staines, H.M.1
Dee, B.C.2
O'Brien, M.3
Lang, H.-J.4
Englert, H.5
Horner, H.A.6
Ellory, J.C.7
Kirk, K.8
-
36
-
-
33749499483
-
Small molecules, big players: The National Cancer Institute's Initiative for Chemical Genetics
-
DOI 10.1158/0008-5472.CAN-06-2552
-
Tolliday N, Clemons PA, Ferraiolo P, Koehler AN, Lewis TA, Li X, Schreiber SL, Gerhard DS, and Eliasof S (2006) Small molecules, big players: the National Cancer Institute's Initiative for Chemical Genetics. Cancer Res 66:8935-8942. (Pubitemid 44521107)
-
(2006)
Cancer Research
, vol.66
, Issue.18
, pp. 8935-8942
-
-
Tolliday, N.1
Clemons, P.A.2
Ferraiolo, P.3
Koehler, A.N.4
Lewis, T.A.5
Li, X.6
Schreiber, S.L.7
Gerhard, D.S.8
Eliasof, S.9
-
37
-
-
0037214509
-
A two-compartment model of osmotic lysis in Plasmodium falciparum-infected erythrocytes
-
Wagner MA, Andemariam B, and Desai SA (2003) A two-compartment model of osmotic lysis in Plasmodium falciparum-infected erythrocytes. Biophys J 84:116-123. (Pubitemid 36026384)
-
(2003)
Biophysical Journal
, vol.84
, Issue.1
, pp. 116-123
-
-
Wagner, M.A.1
Andemariam, B.2
Desai, S.A.3
-
38
-
-
0033003760
-
A simple statistical parameter for use in evaluation and validation of high throughput screening assays
-
Zhang JH, Chung TD, and Oldenburg KR (1999) A simple statistical parameter for use in evaluation and validation of high throughput screening assays. J Biomol Screen 4:67-73.
-
(1999)
J Biomol Screen
, vol.4
, pp. 67-73
-
-
Zhang, J.H.1
Chung, T.D.2
Oldenburg, K.R.3
-
39
-
-
33846694819
-
Scaffold selection and scaffold hopping in lead generation: A medicinal chemistry perspective
-
Zhao H (2007) Scaffold selection and scaffold hopping in lead generation: a medicinal chemistry perspective. Drug Discov Today 12:149-155.
-
(2007)
Drug Discov Today
, vol.12
, pp. 149-155
-
-
Zhao, H.1
|