Fibroblast Growth Factor-2 Represses Platelet-derived Growth Factor Receptor-α (PDGFR-α) Transcription via ERK1/2-dependent Sp1 Phosphorylation and an Atypical cis-Acting Element in the Proximal PDGFR-α Promoter

Journal of Biological Chemistry

Volumn 279, Issue 4, 2004, Pages 2377-2382

  Bonello, Michelle R ^a   Khachigian, Levon M ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ELECTROPHORESIS; GROWTH KINETICS; MUTAGENESIS; NITROGEN; PROTEINS; RNA;

GROWTH FACTORS; SURFACE RECEPTORS;

BIOCHEMISTRY;

CIS ACTING ELEMENT; FIBROBLAST GROWTH FACTOR 2; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; PLATELET DERIVED GROWTH FACTOR A; PLATELET DERIVED GROWTH FACTOR RECEPTOR; TRANSCRIPTION FACTOR SP1;

ANIMAL CELL; ARTICLE; COMPLEX FORMATION; DIMERIZATION; DISULFIDE BOND; ELECTROPHORETIC MOBILITY; GENE REPRESSION; LIGAND BINDING; MULTIGENE FAMILY; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; RECEPTOR AFFINITY; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; VASCULAR SMOOTH MUSCLE;

ANIMALS; CELLS, CULTURED; ENHANCER ELEMENTS (GENETICS); FIBROBLAST GROWTH FACTOR 2; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MUSCLE, SMOOTH, VASCULAR; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); RATS; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA; REGULATORY SEQUENCES, NUCLEIC ACID; SIGNAL TRANSDUCTION; SP1 TRANSCRIPTION FACTOR; TRANSCRIPTION, GENETIC;

ANIMALIA;

EID: 1642535446     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M308254200     Document Type: Article

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